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Ophtho/Derm/Rheum-Pharm
Anti-Histamines
8
Pharmacology
Graduate
12/06/2010

Additional Pharmacology Flashcards

 


 

Cards

Term
what are the adverse effects of First generation H1 blockers
Definition
Sedative, Anticholinergic(dryMouth), alpha block(lightheaded)
Term
What are the adverse effects of the 2nd generation anti-histamines
Definition
Tremors, Headaches
Term

What are the first generation anti-histamines

And which are associated with anticholinergic, sedative properties, and used in motion sickness

Definition

Diphenhydramine: chol, sed, motion

Dimenhydrinate: chol, sed, motion

Tripelenamine: Sedative

Hydroxyzine: Sedative

Meclizine: Motion

Chlorpheniramine

Promethazine

Term
What are the Second Generation Anti-histamines and what are their advantages
Definition

Loratadine

Fexofenadine

Cetirizine

Terfenadine

Less side effects and last 12 hrs

Term
What is the half life of the first generation Anti-histamines
Definition
2-4 hrs
Term
What organs have H2 receptors
Definition

Blood Vessels

Heart

Myocardium

Secretory Tissues

Term
What organs have H1 receptors, H3
Definition

Blood vessels

Capillaries

Brochioles

Uterus

Nerve

H3 brain

Term
Drugs that cause histamine release
Definition
Morphines, Penicillin, NSAID, Polymyxins, Tubocuraine
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