Term
| What is the most common tumor found in bone |
|
Definition
Malignant Metastasis
Then Hematopoeitic malignancies |
|
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Term
What are the most common Primary bone Malignancies found in the following age groups
0-10, 10-20, 20-40,40-60 |
|
Definition
0-10: Ewing's
10-20: Osteosarcoma, Ewing's
20-40: Chondrosarcoma
40-60: Mets |
|
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Term
| What are the radiological Indicators of benign versus malignant |
|
Definition
Benign: Sharp Margin
Sclerotic
Malignant: Onion Skining(Ewing's)
Codman's Triangle(Osteosarcoma)
Spiculated
Osteoid Deposition |
|
|
Term
| What information is typically used to diagnose a bone tumor |
|
Definition
Clinical
Radiologic
Histology |
|
|
Term
| Classify the bone tumors by origin |
|
Definition
Epiphysis: Giant Cell
Chondroblastoma
Upper Metaphysis: Osteosarcoma
Osteoblastoma
Enchondroma
Diaphysis: Ewing's
Lymphoma/Myeloma |
|
|
Term
| What are the indications of a sclerotic verses a ratty/fuzzy margin of a bone tumor |
|
Definition
Sclerotic: Benign
Fuzzy: malignant |
|
|
Term
| What circumstance would you suspect a metastatic lesion over and primary bone tumor |
|
Definition
Older Patient
Multiple Foci
Axial or Proximal limb location |
|
|
Term
| What is a Non-ossifying Fibroma and who is most likely to get it |
|
Definition
Kids
Most likely a metaphyseal fibrous defect which can lead to pathological fracture
Reddish Brown |
|
|
Term
| What is fibrous dysplasia and who is most likely to get it |
|
Definition
Young Adults
Chinese characters formed by bony spicules |
|
|
Term
| What is Albright's (McCune's) Syndrome |
|
Definition
Polystotis Fibrous dysplasia
Cutaneous Pigments(Cafe au Lait)
Endocrine Disturbances(Early Puberty) |
|
|
Term
| What is Osteochondroma and who is likely to get it |
|
Definition
M>F
Epiphyseal defect leading to bone growth out and toward metaphysis (Benign) |
|
|
Term
| What is Multiple Heriditary Exostasis |
|
Definition
| Autosomal dominant disease with multiple Osteochondromas |
|
|
Term
| What is Osteoid Osteoma and who is likely to get it and how is it treated |
|
Definition
M>F, Teens-20's
Prostaglandin Porducing Tumor-NSAID Relief
Looks like Osteogenic Sarcoma
Rx: Remove Surgically |
|
|
Term
| What is Osteoblastoma and who does it affect |
|
Definition
Teens-20s
Large Version of Osteoid Osteoma occuring primarily in Axial skeleton |
|
|
Term
| What is an osteosarcoma and who does it typically affect |
|
Definition
M>F Elderly with History of previous bone disease or Teenagers
Fuzzy irregular, Codman's Triangle, Malignant osteoid(Pink Amorphous) |
|
|
Term
| Where do osteosarcomas typically metastasize |
|
Definition
|
|
Term
| What is an Enchodroma, who do they affect and when can they be malignant |
|
Definition
20-40 yrs old
Soap Bubble islands of epiphyseal cartilage left behind
Malignant in:
Olier's Disease-Multifocal Enchondromas
Marfucci's Syndrome- Olier's with Hemangiomas |
|
|
Term
| What are some indicators that a cartilagentous tumor is malignant |
|
Definition
> 1 Cell per lacunae
Necrosis
Mitotic Figures |
|
|
Term
| What are the features of a chondroblastoma and who does it affect |
|
Definition
10-20 yrs old
Epiphyseal tumor with sclerotic margin |
|
|
Term
| Who does Chondosarcoma typically affect |
|
Definition
| >50 typically in metaphysis |
|
|
Term
| What patients typically get Giant cell bone tumor and what should you know about it |
|
Definition
20-50
Transform, recur in epiphyseal |
|
|
Term
| What's is Ewing's Sarcoma |
|
Definition
Primative Neuroectodermal Tumor is diaphysis
Caused by 11;22 Translocation |
|
|
Term
| What is Jaffe-Campanaci Syndrome? |
|
Definition
| Cafe Au Lait Spots and Multiple Fibromas |
|
|
Term
| Most common sight of bone tumors in the body |
|
Definition
| Distal Femur and Proximal Tibia |
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