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OPC Study Design
KYCOM Block 2
41
Medical
Graduate
09/18/2012

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Cards

Term
what questions should you ask in a study design check list
Definition
is the study relivent
does the study add anything new
what type of research question is beiing asked
was the study design appropirate
did the study methods address the most important potential sources of bias
was the study performed according to the origional protocol
does the study test a stated hypothesis
were the statistical analyses performed correctly
do the data justify the conclusions
are there any conflicts of interest
Term
what are the two primary concerns for a study
Definition
is the study question relivant
does the study add anything new
Term
what three things do you look at to see if a study is relivent
Definition
correlation, association, causation
Term
what is the relationship between correlation and association
Definition
correlation does not imply association
Term
what is association
Definition
a logical connection
Term
what is power
Definition
the probability the test will reject the null hypothesis
Term
list the steps in human study heirarchy begining at the bottom
Definition
case report/study, controlled case study, cohort study, randomized study, practice guidelines, systematic review, meta analysis
Term
what does a systematic review lack
Definition
does not analyze the statistics
Term
what is a parallel study
Definition
people are put into two or more groups randomly and given different treatmet
Term
what is a cross over study
Definition
group gets a drug for some time then the next group does
Term
what is a cohort study
Definition
group a has a disease, group b does not
Term
what is a controlled case study
Definition
off labaled drug use on a patient
Term
what studies have to do with raw data collection
Definition
randomized, cohort, controlled case, case report
Term
what studies have to do with reviews
Definition
meta analysis, systematic review, practice guidelines
Term
what studies are weighted by power
Definition
pilot and full
Term
what are the components of a descriptive study
Definition
population and outcome
Term
what is a descriptive study
Definition
identifies characteristics of the group without collecting scientific data, a raw data collection
Term
what are the types of descriptive studies
Definition
survey and qualitative
Term
what is an analytic study
Definition
doing something with the data, gather data and check it, fact controlled
Term
what are the types of analytic studies
Definition
experimental and observational
Term
what are the experimental studies
Definition
randomized parallel group, randomized crossover
Term
what are the observational studies
Definition
cohort studies, cross sectional (analytic), case controlled
Term
what studies have to do with correlation
Definition
descriptive and ovservational (analytic branch)
Term
what studies have to do with causation
Definition
analytical branch experimental
Term
what is a hypothesis
Definition
does x do y
Term
what is a null hypothesis
Definition
what are the chances your wrong, x does not do y
Term
what type of data in regards to a hypothesis is suspicious
Definition
data irrelivent to the hypothesis
Term
name the 14 steps of experimental design
Definition
1. select a problem
2. determine the dependent variables
3. determine the independent variable
4. determine the number of levels of independent variables
5. determine the possible combinations
6. determine the number of observations
7. redesign if necessary
8. randomize participants
9. meet ethical and legal requirements
10. mathematical model
11. data collection
12. data reduction
13. data verification (outliers)
14. data interpertation
Term
what is a dependent variable
Definition
what you will measure
Term
what is the independent variable
Definition
not manipulated in the experiment
Term
what are examples of independent variables
Definition
age, sex, vision, education, work experience
Term
what is the first experiment design called
Definition
pilot study
Term
what can bias cause in regards to chance
Definition
sampline errors, random error
Term
what is random error
Definition
reduces percision, error multiplies every time you make one not adds
Term
what is sampling error
Definition
can bias results one way or another
Term
what are the systematic errors caused by bias
Definition
choice of participants, which data to collect, conformity of bias (twisting data), technological
Term
what are examples of sampling bias
Definition
socioecnomic bias, genetic bias, age bias, nutritional bias, sex bias, disease bias
Term
what is data collection bias
Definition
only collecting supporting data, equipment not capable of collecting differences
Term
what is survey bias
Definition
interviewer bias (non verbal cues), subject bias (norality, please interviewer)
Term
what is the relationship between effect and sample size
Definition
the bigger the effect, the less you have to sample
Term
what is the correlation between sample size and power
Definition
sample size = power
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