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Ondansetron (Zofran)
n/a
8
Pharmacology
Undergraduate 1
02/15/2012

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Cards

Term
CLASS
Definition
-Non-sedative anti-emetic
-Selective serotonin 5HT3-receptor antagonist
Term
ACTIONS
Definition
-Precise mode of action as anti-emetic is not clear
-Blocks the initiation of the reflex that releases 5HT3-receptors
Term
INDICATIONS
Definition
-Prevention and control of uncomplicated nausea and vomiting
Term
DOSAGE/ROUTE
Definition
8mg oral tablet or 4mg slow IVP (over 2 minutes) or IM
Term
SIDE EFFECTS
Definition
-headache or dizziness
-Body aches, agitation, dysuria, hypotension and rash
-Shivers
Term
CONTRAINDICATIONS
Definition
Known hypersensitivity to the drug
Term
SPECIAL INFO
Definition
-Use with caution in pts with bowel obstruction
-May precipitate if mixed with alkaline solutions
Term
PEDIATRIC NOTE
Definition
-See pediatric drug guide
-4mg oral tab for ages 2-12 yrs
-0.1mg/kg slow IVP (over 2 minutes) or IM
-Max dose 4 mg
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