Term
Ibuprofen
A: Reversibly inhibits COX
B: Analgesic and antipyritic effects
C: Highly protein bound
D: Chronic use inhibits renal PG production |
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Definition
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Term
What TNF drug can be given for JRA if methotrexate and hydroxychloroquine don;t work? |
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Definition
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Term
Aspirin triad includes aspirin intolerance and what other 2 symptoms? |
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Definition
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Term
A child overdosed on aspirin what are the treatments?
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Definition
Alkilization of the urine
Activated charcoal |
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Term
Chronic use of NSAIDS may result in. |
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Definition
Acute renal insufficiency |
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Term
To prevent bleeding problems during surgery, aspirin should be discontinued __ before surgery |
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Definition
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Term
Which of the following regarding inflixinab is true?
- It is a chimeric monoclonal antibody
- It neutralizes TNF α
- It is used for RA
- Human antichimeric AB can limit it's use
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Definition
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Term
NSAIDS are counter indicated for patients that have
- Allergy to sulfonamides
- Allergy to NSAIDS
- The aspirin triad
- Methemoglobinemia
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Definition
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Term
Treatment of osteoarthritis include
- Ibuprofen
- Ketorolac
- Celebrex
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Definition
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Term
Which of the following statements regarding aspirin are correct?
- As an antipyritic it is more effective than tylenol
- It is less likely than tylenol to cause GI irritation
- The late stage of overdose includes respiratory and metabolic acidosis
- NAC is the antidote
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Definition
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Term
The glucocorticoid hormones produce which of the following effects?
- Decrease fat deposition
- Inhibit release and synthesis of thromboxone and leukotrienes
- Increase protein synthesis in most tissue
- Lower plasma glucose levels
- An increase in the number of WBC
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Definition
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Term
Accepted use for celebrex include
- Osteoarthritis
- RA
- Famelial adenomatious polyps
- MS
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Definition
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Term
A patient is treated with a horse derivative Ab, and is experiencing hypersensitivity, what should be used? |
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Definition
Lymphocyte Immunoglobulin (Atgam) |
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Term
Renal impairment resulting from chronic NSAID use include
- AKI
- Intestinal nephritis
- papillary necrosis
- inhibition of renal PG production
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Definition
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Term
Which hypersensitivity involves the Penias? |
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Definition
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Term
In a recent study, short term use of recombinant __ reduced the risk of serious infection in CGD patients |
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Definition
Interferon gamma (actimmune) |
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Term
Which of the following are steroids not used for?
- RA
- eczima
- conjunctivitis
- glomerularnephritis
- lupus
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Definition
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Term
Signs seen in children OD on ASA
- Hyperthermia
- respiratory & metabolic acidosis at late stage
- Tinnitus
- respiratory alkilosis during early stage
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Definition
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Term
long term administration of Dexamethasone would include all except
- Osteoporosis
- Hypoglycemia
- Peptic ulcer
- Cataracts
- Adrenal cortical suppression
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Definition
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Term
how should a patient with a goiter and normal T3 and T4 be treated |
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Definition
subtotal thyroidectamy and T4 |
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Term
administration of lugol's solution will result in |
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Definition
decreased T4 and T3 in the blood |
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Term
Alternating therapy should not be done to treat a patient with |
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Definition
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Term
The principle MOA of fosamax is to |
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Definition
inhibit osteoclast mediated bone resorption |
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Term
Which antiinflamatory steroid should not be given IV?
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Definition
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Term
Which drug can causes TB? |
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Definition
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Term
glucocorticoid produces what effect |
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Definition
inhibit synthesis and release of thromboxone and leukotrienes |
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Term
a high 17-OH and cortisol in the urine means |
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Definition
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Term
synthetic antiinflammatory steroids can induce synthesis of lipocortisin which decreases synthesis of proinflammatory |
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Definition
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Term
Calcitriol, the active form of vit D can treat osteoporosis because it |
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Definition
raises serum Ca, and lowers PTH |
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