Term
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Definition
| abnormal increase in intertsitial fluids within tissues |
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Term
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Definition
60% body weight ,2/3 intracellular .
bu most of ECF in interstitium
<5% in blood plasma |
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Term
| Function of the opposing effect of vascular hydrostatic pressure vs plasma colloid pressure ? |
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Definition
| controls movement of water +low molecular weight salts btw intravascular +interstitial spaces |
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Term
| equilibrium btw capillary hydrostatic +osmotic forces ensures ? |
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Definition
| no net loss or gain of fluid across capillary bed |
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Term
| Causes of accumulation of extravascular fluid |
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Definition
1. increased hydrostatic pressure
2. diminished plasma osmotic pressure
3. movement of water into tissues exceeds lymphatic drainage . |
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Term
| fluid collections in different cavities |
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Definition
| hydrothorax ,hydropericardium ,hydroperitonium/ascites |
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Term
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Definition
| Abnormal accumulatrion of fluid in the peritoneal cavity |
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Term
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Definition
| servere +generalized edema with widespread subcutaneous tissue swelling |
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Term
| Transudate in edema is characterized by? |
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Definition
| increased hydrostatic pressure or reduced plasma proteins |
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Term
| Exudate Edema characterized by ? |
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Definition
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Term
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Definition
1. heart failure
2. hepatic failure
3.malnutrition |
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Term
| Mechanism of heart failure casing edema |
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Definition
| ↓cardiac output → RAAS→ increase in Na +water retention→↑transudation . edema |
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Term
| mechanism of malnutrition causing edema |
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Definition
| ↓hepatic synthesis of proteins,nephrotic syndrome →plasma oncotic pressure . |
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Term
| Causes of Increased hydrostatic pressure |
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Definition
1. impaired venous return (congestive heart failure,constrictive pericarditis,ascites(liver cirhos)venous obstruction)
2. Arteriolar dilation(heat , neurohumoral dysregulation ) |
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Term
| A focal impairment in venous return can result in ? |
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Definition
| regional increases in hydrostatic pressure |
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Term
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Definition
| caused by deep venous thrombosis in lower extremities |
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Term
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Definition
| caused by a generalised increase in venous pressure which is caused by cngestive heart failure |
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Term
| causes of decreased plasma osmotic pressure /hypoproteinemia |
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Definition
| inadequate synthesis or the loss of from circulation of albumin . |
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Term
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Definition
| increased vascular permeability . characterised by exudate |
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Term
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Definition
| typically localized impairment in lymphatic drainage |
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Term
| Causes of impaired lymphatic drainage |
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Definition
1. neoplastic (radiotherapy to the breast → arm edema)
2.inflammatory (filariasis causing elaphantiasis ) |
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Term
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Definition
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Term
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Definition
| legs when standing +sacrum when recumbent |
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Term
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Definition
| finger pressure over substantially oedematous subcutaneous tissue displaces the interstitial fluid and leaves finger print depression |
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Term
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Definition
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Term
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Definition
| setting of left ventricular failure →also seen in renal failure ,pulmonary infections +hypersensitivity reactions |
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Term
| pulmonary edema characterized by |
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Definition
| lungs 2-3X normal weight ,frothy,blood tinged on cut surface |
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Term
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Definition
localized due to neoplasm of abscess , Generalised as in encephalitis, hypertensive crisis or cerebral venous
outflow obstruction. |
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Term
| cerebral edema marcroscopic characteristics |
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Definition
| grossly swollen brain , generalized oedema with distended gyri,narrow sulci with flattening against unyielding skull |
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