Term
| What are the non-sporeforming anaerobes? sporeforming? |
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Definition
non-sporeforming: bacterioides- gram (-), actinomyces
sporeforming: clostridium |
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Term
| Where is bacterioides found? |
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Definition
| normal flora of vagina and colon |
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Term
| What is the clinical picture of bacterioides infection? |
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Definition
intraabdominal infections: peritonitis, local abscesses
metastatic abscesses from hematogenous spread
lung abscess from aspiration |
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Term
| What is the virulence of bacterioides? |
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Definition
antiphagocytic capsule that is abscess promoting
enzymes: lipases, proteases, neuraminidase>promote abscess formation
catalase and SOD
endotoxin w/unusually low endotoxicity |
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Term
| What class of protein synthesis inhibitors is bacterioides resistant to? |
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Definition
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Term
| What is the Tx of choice for all non-sporeforming anaerobes (excluding bacteroides)? |
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Definition
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Term
| What is the morphology of actinomyces? |
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Definition
| gram (+) rod, opportunist, filmaentous (resembles fungi), facultative IC, facultative or obligate anaerobe |
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Term
| Where are actinomyces found? |
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Definition
soil
normal flora of mouth & GI |
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Term
| Which anaerobic organism is associated w/granulomas and pyogenic lesions? |
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Definition
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Term
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Definition
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Term
| Which anaerobic organism has an affinity for the brain? |
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Definition
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Term
| What organism causes chronic suppurative destruction of CT? |
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Definition
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Term
| What organism presents as yellow sulfur granules in the sputum? |
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Definition
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Term
| What organism uses thioglycolate broth or brain heart infusion blood agar? |
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Definition
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Term
| Where is clostridium perfringens found? |
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Definition
| soil, water, sewage, normal flora of GI tract and female genital tract |
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Term
| What anaerobic organism presents w/pain, edema, cellulitis, and crepitation? |
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Definition
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Term
| What does c. perfringens cause? |
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Definition
pain, edema, cellulitis
crepitation
severe necrotizing disease of intestines |
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Term
| What anaerobic organism has alpha toxin (a lecithinase) and other degrading enzymes that promote invasiveness? |
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Definition
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Term
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Definition
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