Term
| What does a dermatofibroma look like microscopically? |
|
Definition
storiform pattern
fibroblasts and collagen
hyperplasia of overlying epidermis |
|
|
Term
|
Definition
single or multiple slow growing, painless, firm skin nodules
gross: redddish-brown
hyerplasia overlying the epidermis |
|
|
Term
|
Definition
may start as nevis > > skin tag
fibrous tissue and mature fat |
|
|
Term
|
Definition
non-metastasizing fibroblastic tumors that invade locally and recur
fibroblasts and myofibroblasts
superficial & deep |
|
|
Term
| What are the superficial fibromatoses? |
|
Definition
palmar (dupytren) and plantar
stiffening of the skin |
|
|
Term
| What are the deep fibromatoses? |
|
Definition
desmoid tumors = BAD
will keep growing
intra-abdominal: treat like malignancy |
|
|
Term
|
Definition
A deep fibromatosis
has a high recurrence
treat like a malignant tumor |
|
|
Term
| What fibrous tissue tumor has a herring-bone pattern? |
|
Definition
|
|
Term
| What is seen in a dermatus fibrosarcoma protuberans? |
|
Definition
nodular, polyploid lesion
dermis & invasion of subcutaneous tissue
slow growing
storiform pattern
trunk/extremities |
|
|
Term
| When do you see palmar or plantar stiffening of the skin? |
|
Definition
|
|
Term
| Are dermatofibromas painful? |
|
Definition
|
|
Term
| Where is a fibrosarcoma most common on the body? |
|
Definition
|
|
Term
|
Definition
most common on extremities
arises from deep CT
has a herring-bone pattern
malignant |
|
|
Term
| What are the 2 types of reactive pseudosarcomas? |
|
Definition
nodular fascitis
myositis ossificans |
|
|
Term
| What should you assume about deep tumors? |
|
Definition
| malignant until proven otherwise |
|
|
Term
|
Definition
|
|
Term
| What is the most common sarcoma of adults? |
|
Definition
malignant fibrohistiocytoma (MFH)
unknown cell of origin
histiocytes & fibroblasts
storiform pattern |
|
|
Term
| What is the most common soft tissue tumor of adults, and when does it typically occur? |
|
Definition
lipoma
4th-6th decades of life |
|
|
Term
|
Definition
soft, solitary, freely movable, painless
well-defined (encapsulated)
grows slowly from 1-5cm
lobules of MATURE adipost tissue |
|
|
Term
| Where do you typically find spindle cell lipomas? |
|
Definition
| subcutaneous tissue of neck and back of men ages 45-60 |
|
|
Term
| Where do you see bipolar spindle cells? |
|
Definition
|
|
Term
| Where are angiolipomas typically seen? |
|
Definition
| in the subcutaneous layer of the forearm of young adults |
|
|
Term
| Why can angiolipomas be painful? |
|
Definition
| they can form microthrombi |
|
|
Term
| Where do you see a pleiomorphic (atypoid) lipoma? |
|
Definition
|
|
Term
| In what age group do you see lipoblastomas? |
|
Definition
| a BENIGN tumor exclusively children under age 6 |
|
|
Term
|
Definition
| painless, deposits of fat beneat skin of neck, upper trunk, arms/legs |
|
|
Term
|
Definition
arises from brown fat
benign
seen in infants and adults |
|
|
Term
| What are the types of liposarcomas? |
|
Definition
well-differentiated (lipoma-like and sclerosing)
round cell
myxoid
pleimorphic |
|
|
Term
| What is the most common type of liposarcoma? |
|
Definition
|
|
Term
| Describe well-differentiated liposarcomas. |
|
Definition
occur in ages 50-70
chicken-wire vessels
lipoma-like or sclerosing |
|
|
Term
| What is the prognosis for each type of liposarcoma? |
|
Definition
well-diff & myxoid = excellent
round cell & pleimorphic = poor |
|
|
Term
| Where are smooth muscle tumors most frequently found? |
|
Definition
|
|
Term
| Where do leiomyomas arise from? |
|
Definition
arector pili muscles
nipple erector muscles
tunica dartos & media |
|
|
Term
| What condition is associted w/rhabdomyosarcoma of the heart? |
|
Definition
|
|
Term
|
Definition
|
|
Term
| What is the most common soft tissue sasrcoma of childhood and adolescence? |
|
Definition
|
|
Term
| What are the age groups associated w/each type of rhabdomyosarcoma? |
|
Definition
embryonal: < 10yo
alveolar: 10-25yo
pleiomorphic: adults |
|
|
Term
| Which type of rhabdomyosarcoma has a polyploid/grape-like mass when under a mucosal membrane? |
|
Definition
|
|
Term
| Where are pleiomorphic rhabdomyosarcomas most commonly seen? |
|
Definition
the thigh of adults
it grows rapidly, 30% 5 year survival |
|
|
Term
| What are the malignant vascular tumors and the characteristics of each? |
|
Definition
angiosarcoma: head/neck of adults
lymphangiosarcomas: older people; in extremities subjected to longstanding lymphedema; assoc w/post-mastectomy lymphedema
kaposi's: assoc w/AIDS; slit-like vasc spaces w/RBCs, reddish nodules, cutaneous nodules of distal leg |
|
|
Term
| what diseases are assoc w/multiple fibromas? |
|
Definition
Neurofibromatosis
Multiple Endocrine Adenoma Syndrome |
|
|
Term
| What age group is most commonly affected by synovial tumors? |
|
Definition
|
|
Term
|
Definition
|
|
Term
| What are the types of fibromas? |
|
Definition
| dermatofibroma, recurrent infantile digital fibroma, acquired digital fibrokeratoma, fibroma molle |
|
|
Term
| lobules of mature adipose tissue, encapsulated |
|
Definition
|
|
Term
| Where do spindle cell lipomas usually occur? |
|
Definition
| neck/back of men ages 45-60 |
|
|
Term
| Where are pleimorphic rhabdomyosarcomas seen? |
|
Definition
|
|
Term
| Which tumors are commonly found in the neck? |
|
Definition
| spindle cell lipoma, pleiomorphic lipoma, embryonal rhabdo, hemangioma , |
|
|
