Term
| osteophytes and Heberden's nodes |
|
Definition
|
|
Term
| deterioration and loss of cartilage over eyars; weight bearing joints |
|
Definition
|
|
Term
| systemic, relapsing, chronic, destructive synovitis |
|
Definition
|
|
Term
| Does RA affect women or men more? |
|
Definition
|
|
Term
| What is the genetic association w/RA? |
|
Definition
| HLA DR4 & DR1 class II MHC |
|
|
Term
| What are the characteristics of hands w/RA? |
|
Definition
claw-like hand w/ulnar deviation
swan neck deformity: flex DIP, extend PIP
Boutinniere: oppsoite |
|
|
Term
| In what condition do you see swan neck deformity? |
|
Definition
|
|
Term
| What do you see clinically/microscopically w/RA? |
|
Definition
lymphocytic infiltrate
pannus formation
ankylosis
synovium invades joint space
subcutaneous nodules w/necrotic center and pallisading macrophages |
|
|
Term
| What are complications of RA? |
|
Definition
| glaucoma, pleuritis, skin nodules, sjogren's, pericarditis, splenomegaly, lymphadenopathy, reynaud's, cardiac, pulm & vasc involvement, shortened life expectancy and QOL |
|
|
Term
| What are the secondary causes of gout? |
|
Definition
| decreased excretion: glomuerular or tubular defect, drugs, PB poisoning of kidneys |
|
|
Term
| What gene is assoc w/ankylosing spondylitis? |
|
Definition
|
|
Term
| Who is most affected by ankylosing spondylitis, and what joints? |
|
Definition
adolescent males
sacroiliac joints |
|
|
Term
| What causes reactive arthritis, and what is the triad ? |
|
Definition
Autoimmune reaction to genitourinary or GI infection
triad: arthritis
conjuctivitis
non-gonococc urethritis or cervicitis |
|
|
Term
| In what condition do you see sausage fingers/toes? |
|
Definition
|
|
Term
| What joints are affected in psoriatic arthritis? |
|
Definition
DIP of hands & feet
large joints |
|
|
Term
| What is the most common mass that develops in the hands? |
|
Definition
| ganlgion: fluid filled lesion in joint capsule |
|
|
Term
|
Definition
occurs in mid-life
highly malignant
in leg as painful, deep, bulky tumor
biphasic pattern w/hemorrhage, necrosis, calcification |
|
|
