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Odontogenic Cysts
path exam 1
87
Pathology
Graduate
02/12/2017

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Cards

Term
Most common odontogenic cyst
Definition
periapical cyst
Term
Describe radiographic features of PA cysts
Definition
Unilocular radiolucency

Long-standing cysts; root resorption
Term
Clinical features of PA cysts
Definition
3rd to 6th decades
Maxilla-anterior teeth
Mandible-posterior teeth
Asymptomatic
Nonvital tooth
Term
Are PA cysts symptomatic or asymptomatic?
Definition
asymptomatic
Term
Where are PA cysts in maxilla and mandible?
Definition
Anterior maxilla, posterior mandible
Term
What are the microscopic features of PA cyst?
Definition
Cyst lined by a stratified squamous epithelium
Term
When thinking of PA cysts, what is included in the differential diagnosis?
Definition
PA granuloma, PA scar, PA cemento-osseous dysplasia (early stage), odontogenic tumors, central giant lesion, traumatic bone cyst, metastatic lesion
Term
What are treatments for PA cysts?
Definition
Endodontic therapy if the tooth is restorable, extraction if the tooth is not restorable, curettage of the apical zone, residual cyst may develop if the cyst was incompletely removed
Term
What is the second most common odontogenic cyst?
Definition
dentigerous cyst
Term
Clinical features of dentigerous cysts
Definition
2nd to 3rd decades
Slight male predilection
Impacted teeth--mandibular third molars and maxillary canines
Asymptomatic
Term
Are dentigerous cysts symptomatic or asymptomatic?
Definition
asymptomatic
Term
Describe radiographic features of dentigerous cysts
Definition
Well-defined unilocular or occasionally multilocular.

Radiolucency associated with crown of impacted tooth.

Reposition of roots of adjacent erupted teeth
Term
What are the microscopic features of dentigerous cysts?
Definition
Cyst lined by a nonkeratinized stratified squamous epithelium
Term
When thinking of dentigerous cysts, what is included in the differential diagnosis?
Definition
Enlarged dental follicle, ameloblastoma, OKC, AOT
Term
What are treatments for dentigerous cysts?
Definition
Removal of the associated tooth and surgical enucelation
Term
Clinical features of lateral periodontal cysts
Definition
5th to 7th decades
Male predilection
Along the lateral root surface of a vital tooth/between the roots of vital teeth
Asymptomatic
75% to 80% mandibular premolar-canine-lateral incisor area
Term
Are lateral periodontal cysts associated with vital or non-vital teeth?
Definition
Vital
Term
Describe radiographic features of lateral periodontal cysts
Definition
Well-defined radiolucency (less than 1.0 cm in greatest diameter)

"Tear-drop" shaped

Occasionally multiolocular radiolucency-botryoid odontogenic cyst
Term
What are the microscopic features of a lateral periodontal cyst?
Definition
Cyst lined by a thin, nonkeratinized epithelium

Clusters of glycogen-rich, clear epithelial cells forming focal nodular thickenings of the cyst lining
Term
When thinking of PA cysts, what is included in the differential diagnosis if unilocular?
Definition
Lateral radicular cyst, OKC, odontogenic tumor (ameloblastoma, squamous odontogenic tumor)
Term
When thinking of PA cysts, what is included in the differential diagnosis if multilocular?
Definition
OKC, ameloblastoma, central giant cell lesion
Term
How do you treat lateral periodontal cysts?
Definition
conservative enucleation
Term
Clinical features of odontogenic keratocysts
Definition
any age – peak incidence within 2nd and 3rd decades
Slight male predilection
Mandible: posterior portion of the body and the ramus region
Asymptomatic
Large lesions may be associated with pain,
swelling and drainage
Term
Where do you see odontogenic keratocysts?
Definition
Mandible: posterior portion of the body and the ramus region
Term
Describe radiographic features of odontogenic keratocysts
Definition
Well- defined unilocular or multilocular radiolucency

40% associated with an unerupted tooth

Multiple cysts- Nevoid basal cell carcinoma syndrome (Gorlin syndrome)
Term
What are the microscopic features of odontogenic keratocysts?
Definition
Cyst lined by parakeratinized stratified squamous epithelium

6 to 10 cell layers cells thick

Hyperchromatic and palisaded basal cell layer

Corrugated parakeratotic surface

Keratin filled lumen

Satellite cysts
Term
When thinking of odontogenic keratocysts, what is included in the differential diagnosis if unilocular/multilocular associated with a tooth?
Definition
Dentigerous cyst, ameloblastoma, odontogenic myxoma, AOT and ameloblastic fibroma
Term
When thinking of odontogenic keratocysts, what is included in the differential diagnosis if unilocular/multilocular non-associated with a tooth?
Definition
Central giant cell lesion, traumatic bone cyst and aneurismal bone cyst
Term
How do you treat a odontogenic keratocyst that is a small lesion?
Definition
surgical enucleation
Term
How do you treat a odontogenic keratocyst that is a large lesion?
Definition
More extensive surgical resection, marsupialization
Term
What is the recurrence rate of odontogenic keratocysts?
Definition
High recurrence rate: 10%-30%
Term
Clinical features of orthokeratinized odontogenic cysts
Definition
Age: Young adults
Male predilection (2:1)
Mandible – posterior areas
Asymptomatic
Term
Where do you find orthokeratinized odontogenic cysts?
Definition
Posterior areas of mandible
Term
Radiographic features of orthokeratinized odontogenic cysts
Definition
Well-defined unilocular radiolucency, occasionally multilocular

Commonly associated with an unerupted mandibular third molar
Term
What are the microscopic features of orthokeratinized odontogenic cysts?
Definition
Cyst lined by a orthokeratinized stratified squamous epithelium
Term
When thinking of orthokeratinized odontogenic cysts, what is included in the differential diagnosis?
Definition
Dentigerous cyst, OKC, ameloblastic fibroma, ameloblastoma
Term
What are treatments for orthokeratinized odontogenic cysts?
Definition
Removal of the associated tooth, enucleation and curettage
Term
Clinical features of orthokeratinized odontogenic cysts
Definition
Age: Young adults
Male predilection (2:1)
Mandible – posterior areas
Asymptomatic
Term
Where do you find orthokeratinized odontogenic cysts?
Definition
Posterior areas of mandible
Term
Radiographic features of orthokeratinized odontogenic cysts
Definition
Well-defined unilocular radiolucency, occasionally multilocular

Commonly associated with an unerupted mandibular third molar
Term
What are the microscopic features of orthokeratinized odontogenic cysts?
Definition
Cyst lined by a orthokeratinized stratified squamous epithelium
Term
When thinking of orthokeratinized odontogenic cysts, what is included in the differential diagnosis?
Definition
Dentigerous cyst, OKC, ameloblastic fibroma, ameloblastoma
Term
What are treatments for orthokeratinized odontogenic cysts?
Definition
Removal of the associated tooth, enucleation and curettage
Term
Clinical features of granular odontogenic cysts
Definition
Age: Wide age range – 2nd to 9th
decades
M=F
80% to 85% - anterior mandible
Jaw expansion – locally aggressive
It tends to cross the midline.
Term
Where do you find odontogenic cysts?
Definition
anterior mandible (80% to 85%)
Term
Odontogenic cyst associated with jaw expansion
Definition
granular odontogenic cyst
Term
Describe radiographic features of granular odontogenic cysts
Definition
Well-defined multilocular radiolucency, occasional unilocular
Term
What are the microscopic features of granular odontogenic cysts?
Definition
Cyst lined by a nonkeratinized squamous epithelium. Focal mucous cells, pseudocysts. Occasionally, cilia may be noted
Term
When thinking of granular odontogenic cysts, what is included in the differential diagnosis?
Definition
central giant cell lesion, ameloblastoma
Term
What are treatments for granular odontogenic cysts?
Definition
Enucleation and curettage en bloc resection

30% recurrence rate
Term
What is the recurrence rate of granular odontogenic cysts?
Definition
30%
Term
Clinical features of calcifying odontogenic cysts?
Definition
Age: 2nd to 3rd decades
Some authors mention female predilection
Some authors mention 70% of COCs are
seen in the maxilla
65% - in the incisor and canine areas
It may be associated with cortical expansion
13% to 30% of cases are peripheral (extraosseous)
Term
What is another name for calcifying odontogenic cysts?
Definition
Gorlin's cyst
Term
Which odontogenic cyst has a potential female predilection?
Definition
Calcifying odontogenic cyst (Gorlin's cyst)
Term
Where in the mouth do you find calcifying odontogenic cysts?
Definition
incisor and canine areas (65%)

maxilla (70%)
Term
Radiographic features of calcifying odontogenic cysts?
Definition
Well-defined unilocular or multilocular radiolucency
Within the radiolucency there may be scattered, irregular radiopacities
1/3 of the cases are associated with an unerupted tooth
May cause tooth resorption or divergence of
adjacent teeth
Term
What are the microscopic features of calcifying odontogenic cysts?
Definition
Cyst lined by ameloblastic-like epithelial cells, basal cell palisading, ghost cells, dysplastic dentin
Term
What is the differential diagnosis of calcifying odontogenic cysts if there is a radiolucent lesion?
Definition
Dentigerous cyst, OKC, ameloblastoma
Term
What is the differential diagnosis of calcifying odontogenic cysts if there is a mixed radiolucent/radiopaque lesion?
Definition
AOT, CEOT, odontoma, ameloblastic fibroma
Term
How do you treat calcifying odontogenic cysts?
Definition
Enucleation, removal of the associated tooth (cases associated with an unerupted tooth)
Term
Clinical features of eruption cysts
Definition
Age: Children younger that age 10
Translucent swelling in the gingival mucosa overlying the crown of an erupting deciduous or permanent tooth
Purplish-brown color – eruption hematoma
Molar and maxillary incisors
Term
Where do you find eruption cysts in the oral cavity?
Definition
molar and maxillary incisors
Term
Describe radiographic features of eruption cysts
Definition
no radiographic finding
Term
Microscopic features of eruption cysts
Definition
Cyst lined by a thin layer of nonkeratinizing squamous epithelium
Term
Differential diagnosis of eruption cyst
Definition
diagnostic clinical appearance
Term
Treatment of eruption cysts
Definition
Not treatment; some cases may need simple excision of the roof of the cyst to permit eruption of the tooth
Term
Clinical features of gingival cyst of the newborn
Definition
Age: Newborn
Multiple whitish nodules along the alveolar ridge
Maxilla more affected than mandible
May occur along the midline of the palate (Epstein’s pearls)
Asymptomatic
Term
What is another name for gingival cyst of the newborn?
Definition
Bohn's nodules
Term
Where do you find gingival cyst of the newborn?
Definition
maxilla, along midline of the palate (Epstein's pearls)
Term
Describe radiographic features of gingival cyst of the newborn
Definition
no radiographic finding
Term
Microscopic features of gingival cyst of the newborn
Definition
Cyst lined by a thin, flattened epithelium with a parakeratotic surface. The lumen contains keratinaceous debris
Term
Treatment of gingival cyst of the newborn
Definition
no treatment
Term
Clinical features of gingival cyst of the adult
Definition
Age: 5th to 6th decades
60% to 75% - Mandibular canine and premolar area
Facial gingival or alveolar mucosa
Painless, bluish or bluish–gray domelike swelling usually less than 0.5 cm in diameter
Term
Where do you find gingival cyst of the adult in the oral cavity?
Definition
mandibular canine and premolar area; facial gingiva or alveolar mucosa
Term
Radiographic findings of gingival cyst of the adult
Definition
no radiographic findings
Term
Microscopic features of the gingival cyst of the adult
Definition
Cyst lined by a thin, flattened epithelium. With or without focal plaques that contain clear cells
Term
What is included in the differential diagnosis of the gingival cyst of the adult?
Definition
Mucocele, parulis, peripheral odontogenic tumor
Term
What is the treatment for the gingival cyst of the adult?
Definition
simple surgical excision
Term
Cyst(s) lined by a stratified squamous epithelium
Definition
periapical cyst
Term
Cyst(s) lined by a nonkeratinized stratified squamous epithelium
Definition
dentigerous cyst, granular odontogenic cyst, eruption cyst
Term
Cyst(s) lined by a thin, nonkeratinized epithelium
Definition
lateral periodontal cyst
Term
Cyst(s) that have clusters of glycogen-rich, clear epithelial cells forming focal nodular thickenings of the cyst lining
Definition
lateral periodontal cyst
Term
Cyst(s) lined by a orthokeratinized stratified squamous epithelium
Definition
orthokeratinized odontogenic cyst
Term
Cyst(s) lined by ameloblastic-like epithelial cells
Definition
calcifying odontogenic cyst (Gorlin's cyst)
Term
Cyst(s) lined by a thin, flattened epithelium with a parakeratotic surface
Definition
gingival cyst of the newborn (Bohn's nodules)
Term
Cyst(s) lined by a thin, flattened epithelium
Definition
gingival cyst of the adult
Term
Cyst(s) with no radiographic findings
Definition
eruption cyst, gingival cyst of the newborn (Bohn's nodules)< gingival cyst of the adult
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