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Ocular Physiology Test 1
Eyelid structure and function Part 2
76
Physiology
Professional
09/22/2007

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Term
Is the palpebral or orbital orbicularis more excitable?
Definition
Palpebral
Term
What part of the orbicularis is involved in rapid blinks, reflex, spontaneous blinks and basic blinks?
Definition
Palpebral
Term
What part of the orbicularis is involved in forced closure blinks?
Definition
Orbital
Term
The levator palpebrae superioris elevates what part of the lid?
Definition
Upper lid
Term
Are the right and left levator palpebrae superioris yoked?
Definition
Yes - they receive equal innervation
Term
What muscle is responsible for the tonic lid position?
Definition
Tarsal muscle of Meuller
Term
The superior tarsal muscle of Meuller runs from the levator palpebrae superioris connective tissue sheath, under the levator palpebrae superioris itself, and finally to where?
Definition
Superior tarsal plate
Term
The inferior tarsal muscle or Mueller runs from where to the inferior tarsal plate?
Definition
IR/IO connective tissue sheath
Term
What is the only muscle that depresses the lower lid?
Definition
Tarsal muscle of Meuller
Term
The Meuller muscle receives what type of nervous system innervation?
Definition
Sympathetic Nervous system
Term
What is Bell's phenomenon?
Definition
It is the upward and outward rotation of the globe that happens with forced closure and sleeping. It is a normal protective response
Term
The Bell's phenomenon signals an intact what in an unconscious patient?
Definition
Intact midbrain
Term
When will Bell's phenomenon disappear?
Definition
If you have a brainstem lesion above the pons
Term
Are Bell's phenomenon and Bell's Palsy the same thing?
Definition
NO - Bell's palsy involves twitching, weakness, or paralysis of the face due to irritation of the facial nerve (CN 7)
Term
How does the lid receive its sensory innervation?
Definition
Through the ophthalmic branch (V1) of the Trigeminal nerve (CN 5)
Term
The sensory plexus for the lid is deep to the palpebral fibers of the orbicularis oculi so it requires what for anestheses?
Definition
Deep penetration
Term
Is a hordeolum or a chalazion painful?
Definition
A hordeolum
Term
What is preseptal cellulitis?
Definition
An infection of the preseptal region of the eyelid. It can start as a hordeolum
Term
What is the eyelid disorder that is marked by cholesterol deposits on the upper medial eyelid margin?
Definition
Xanthelasma
Term
In spastic entropion this portion of the orbicularis oculi is overeactive and causes override of the tarsal portion.
Definition
Septal portion
Term
What is atonic ectropion of the lower lid?
Definition
It is a loss of orbicularis oculi tonus
Term
Paralytic ectropion of the lower lid is caused by what?
Definition
Flaccid paresis of CN 7
Term
Ankyloblepharon is characterized by what?
Definition
Adhesions of the upper and lower lid
Term
What is blepharophimosis?
Definition
Inverted epicanthal folds
Leads to reduced fissure
Term
What is cryptophthalmos?
Definition
It is where there is no lid opening at all - lids are fused
Ankyloblepharon totale
Term
What causes a coloboma?
Definition
Failed closure of the fetal fissure
Term
What is blepharochalasis?
Definition
It is a loss of orbital septum allowing a fat prolapse - saggy lids
Term
Are the elderly the only people to get blepharochalasis?
Definition
NO - Young people can get the condition following chronic edema
Term
Is blepharochalasis a ptosis?
Definition
NO - The input and tonus of the levator is normal but the tissues are drooping. It is a Psuedotosis
Term
What can cause a blepharospasm? What does it look like?
Definition
An irritated CN 7 can cause it.
The eyelids will not unclamp
Term
What is a myokymia? What causes it?
Definition
It is an eyelid twitch.
It can be caused by stress, lack of sleep, or idiopathic reasons
Term
In Bell's palsy, are emotional or voluntary actions affected?
Definition
Not as affected
It is mainly your voluntary actions that are affected
Term
What are some symptoms of Bell's palsy? Is it usually bilateral or unilateral? What percentage usually recovers?
Definition
Lagophthalmos and widened palpebral fissure, facial twitching, etc
Usually unilateral
86% recover completley
Term
The restinf lid position depends upon the resting tonus of what two muscles?
Definition
The levator palpebrae superioris and Mueller's muscle
Term
The resting lid position can vary with what state?
Definition
Your arousal state (serum level of catecholamines)
Term
If there is asymmetry between your two vertical palpebral fissures is this a problem?
Definition
YES - It has pathological significance
Term
In congenital ptosis, with downgaze the normal lid moves where?
Definition
Lower
Term
What causes a Psuedo-Grafe?
Definition
Abberant regeneration of CN 3
Term
What are some signs and symptoms of a Pseuo-Grafe?
Definition
It is a mix-up of what should normally happen with the eyelids.
Ptosis, lid elevation with downgaze or adduction. You may have a pupil that is non-reactive to light but that constricts with adduction.
Term
In Marcus-Gunn Phenomenon what happens because of bad wiring between the brain, jaw and lid?
Definition
“Jaw winking” – lid retraction with mouth open or lateral jaw movement
Term
What is Collier’s sign? Signs and symptoms?
Definition
Symmetric upper lid retraction – 2nd most common cause of lid retraction
Characteristic stare (staring all the time) and commonly upgaze paresis
Term
What causes Collier’s sign?
Definition
Pretectal/dorsal midbrain lesion
Term
What is the most common cause of lid retraction?
Definition
Hyperthyroidism – Grave’s Disease
Term
What is Dalrymple’s Sign?
Definition
Widening of the palpebral fissure due to excessive tonus of Muller muscle or excessive tonus of the levator palpebrae
Term
Widening of the palpebral fissure due to retraction of the upper eyelids is responsible for the apparent exophthalmos seen in what?
Definition
Thyrotoxicosis – Complication associated with Grave’s disease
Term
The principal reason for the prominent appearance of the eye is what?
Definition
Lid retraction
Term
With Von Graefe’s Sign, the patient manifests a “lid-lag” because of a mismatch of signals between the globe and lid. In downgaze, what can be seen in these patients?
Definition
Inability of the upper lid to follow the movements of the globe
Term
What is a blepharospasm?
Definition
Bilateral, involuntary intermittent or persistent spasmodic closure of the eyelids with active contraction of the orbicularis oculi and the procerus and corrugator muscles.
Term
What is blepharoptosis?
Definition
Drooping of the upper eyelid due to paralysis of the occulomotor nerve (CN3) or sympathetic nerve or by excessive weight of the upper eyelids
Term
What is blepharoclonus?
Definition
Exaggerated reflex blinking
Term
What is blepharophimosis?
Definition
Decreased size of the palpebral fissure, often due to increased distance between the inner canthui (telecanthus) or drooping upper eyelid (blepharoptosis)
Term
The eyelids close in a zipper fashion. What moves where?
Definition
Upper eyelid moves down and nasal, the lower lid moves nasally (depressed momentarily when contracted by upper lid), the lateral canthus moves nasally and the medial canthus stays stationary
Term
Of the three types of blinking, spontaneous, reflex, and voluntary, which is the most common yet the mechanism is the least understood?
Definition
Spontaneous
Term
Reflex blinking can be elicited by what kind of stimulation?
Definition
Sensory – touch, auditory, light, irritation
Term
Voluntary blinking is accomplished by what two parts of the orbicularis oculi?
Definition
Preseptal and pretarsal
Term
Spontaneous (basic) blinking is elicited by what muscle?
Definition
Palpebral orbicularis oculi
Term
Are basic blinks (spontaneous) 100% complete?
Definition
NO – 75% complete under ideal conditions. They can be even less complete when attending to something or doing activities (ie computer).
Term
How many spontaneous blinks does an adult average per minute? Newborn?
Definition
Adult – 12-15x/min
Newborn – less than 3x/min
Term
Although the reflex stimulus that initiates a spontaneous blink is largely unknown, what do some believe it is do to?
Definition
The tear film becomes hypertonic with increased exposure to the air. This is then detected by nerve endings (eyelid? eye?) which then stimulate the lid to come down
Term
Can your number of basic blinks vary?
Definition
YES – Can vary with stimuli, conditions, or emotion
Term
Blinking data shows that you can _______ your eye twice as fast as you can ______ it.
Definition
Close; open
Term
In a protective tactile reflex blink, what are the afferent and efferent pathways?
Definition
Afferent – CN5 to Gasserian ganglion to midbrain
Efferent – CN 7 nucleus to orbicularis oculi
Term
Does a tactile reflex blink require cortical input? Can it be reduced with CL wear?
Definition
YES – absence most commonly due to CN 5 damage
YES
Term
How do you quantify a tactile reflex blink?
Definition
An aesthesiometer or cotton wisp
Term
You receive a visual reflex that suprises you or dazzles you. What are the afferent and efferent pathways? Is it cortically dependent?
Definition
Afferent – CN 2 to superior colliculus and supraoptic nuclei
Efferent – CN 7 nucleus to orbicularis oculi
It is not cortically dependent – it is entirely brainstem mediated
Term
How can this dazzle reflex blink be lost?
Definition
With a mesencephalic lesion
Term
You receive a visual reflex that appears to be menacing. What are the afferent and efferent pathways? Is it cortically dependant? Is it a learned reflex?
Definition
Afferent – CN 2 to LGN to primary visual cortex and associated fibers to Rolandic area
Efferent – CN 7 nucleus to orbicularis oculi
It is cortically dependent – requires input from occipital lobe and parietal and frontal lobes mediate your visual attention
It may be a learned reflex (after age 2-4 months)
Term
A book drops on the floor unexpectedly and elicits a auditory (stapedius) reflex blink. What are the afferent and efferent pathways?
Definition
Afferent – CN 8 to auditory nucleus
Efferent – CN 7 nucleus to orbicularis oculi
Term
The cortical control of an elevating lid movement occurs where?
Definition
Frontal cortex (oculogyric center)
Term
The cortical control of a closure lid movement occurs where?
Definition
Motor cortex (precentral gyrus)
Term
The eyelids move with similar speed and conjugacy to what EOM’s?
Definition
Vertical
Term
In downgaze, the upper lid depresses due to the relaxation of what muscle and the tonus of what other muscle? This is an example of what law?
Definition
Relaxation of the levator palpebrae superioris and tonus of orbicularis oculi
Sherrington’s Law
Term
The upper eyelid elevates with upgaze synergistically with what muscle? Why does this occur?
Definition
Superior rectus; they share a common facial sheath
Term
Is there an association of ptosis and superior rectus palsy?
Definition
YES
Term
Both levator palpebrae superiori are under the control of what nucleus of CN3?
Definition
Central caudate nucleus
Term
In the midbrain, what nucleus inhibits the central caudate nucleus?
Definition
Nucleus of posterior commisure
Example – In downgaze the nucleus of posterior commisure fires and inhibits the central caudate nucleus allowing eyelid relaxation
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