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OCTC License Practical Nursing
Pharmacology Test 4
54
Nursing
Professional
02/18/2013

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Cards

Term
slow or retart the multoplication of bacteria
Definition
bacteriostatic
Term
destroy bacteria
Definition
bactericidal
Term
destroy large # of different types of bacteria from the same strain
Definition
broad spectrum
Term
specific to particular bacteria
Definition
narrow spectrum
Term
ability of bacteria to produce substances that inactivate or destroy the antibiotic
Definition
bacterial resistance
Term
drug that has bacteriostatic-inhibit activity of folic acid in bacterial cell metabolism
Definition
sulfonamides/sulfa drugs
Term
used to treat UTI's and otitis media
Definition
sulfa drugs
Term
drugs that can cause adverse reactions of hematologic changes
Definition
sulfa drugs
Term
decreased platelets
Definition
thrombocytopenia
Term
anemia due to deficient RBC production in the bone marrow
Definition
aplastic anemia
Term
decreased WBC
Definition
leukopenia
Term
S/S of Stevens-Johnson Syndrome
Definition
lesions,fever
Term
help prevent bacteria from attaching to the walls of the urinary tract
Definition
cranberries
Term
what are the 3 groups of penicillians?
Definition

-natural

-semisynthetic

-extended-spectrum

Term
enzyme that inactivates penicillin
Definition
penicillinase
Term
ex of aminopenicillins/Broad Spectrum
Definition
amoxicillin,ampicillin
Term
bind with penicillin to protect from destruction
Definition
beta-lactamase inhibitors
Term
used to destroy bacteria such as Pseudomonas
Definition
extended spectrum penicillins
Term
used to dermine if a specific type of bacteria is sensitive to penicillin
Definition
culture and sensitivity test
Term
bacteria that respond to penicillin therapy?
Definition
pneumococci,group A beta-hemplytic streptococci
Term
can be used as prevention against potential secondary bacterial infections in a pt with a viral infection
Definition
PCN
Term
there is a decreased effectiveness of oral contraceptives with  the use of?
Definition
PCN
Term
inflammation of tongue
Definition
glossitis
Term
inflammation of mouth;dry mouth
Definition
stomatits
Term
adverse reactions of PCN
Definition
glossitis,stomatitis,anemia,thrombocytopenia,leukopenia
Term
S/S of hypersensitivity to PCN
Definition
angioedema,hypotension
Term
person allergic to PCN have a higher chance of allergy to what?
Definition
cephalosporins
Term
allergy to drugs in the same or related groups
Definition
cross sensitivity/cross allergenicity
Term
destruction of lg #s of nonpathogenic bacteria by the antibiotic alters the chemical environment,allowing for uncontrolled growth of bacteria or fungal microorganisms which are not affected by the antibiotic being given
Definition
superinfections
Term
type of superinfection that occurs in the bowel
Definition
bacterial
Term
type of superinfection that occurs in the mouth,vagina, anal/ genital areas
Definition
fungal
Term
s/s of pseudomembranous colitis
Definition
severe diarrhea with blood & mucous,fever,abdominal cramps
Term
clients must wait how long after injection of PCN?
Definition
30 min
Term
oral PCN can result in?
Definition
fungal superinfection of the oral cavity
Term
what can pts do to reduce the risk of fungal superinfection?
Definition
eat yogurt,buttermilk,or acidophilus capsules
Term
effective in tx of infections with all strains of bacteria affected by PCN and some strains that are resistant
Definition
Cephalosporins
Term
drug that has a beta-lactam ring and target the bacterial cell wall, making it defective and unstable;bactericidal
Definition
cephalosporins
Term
used for resp infections,otitis media,bone/joint infections,genitourinary tract infections
Definition
cephalosporins
Term
what are the adverse reactions of cephalosporins?
Definition
malaise,nephrotoxicity,aplastic anemia,toxic epidermal necrolysis,disulfiram
Term

drug that inhibit bacterial protein synthesis

-bacteriostatic

Definition
tetracyclines
Term
used in tx of infections caused by a wide range of gram neg and gram pos microorg.; used when allergic to PCN or cephalosporin
Definition
tetracyclines
Term
tetracyclines are not given to children under the age of what?
Definition
9
Term
why arent tetracyclines given to children?
Definition
permanent yellow-gray-brown dicoloration of the teeth
Term
drug used in bactericidal-block step in protein synthesis,disrupt function of bacterial cell wall,causing cell death
Definition
aminoglycosides
Term
used to treat infections by gram neg microorg.,reduce bacteria in the bowel for pts. having abdominal surgery or those in hepatic coma
Definition
aminoglycosides
Term
what meds are given before surgery to reduce intestinal bacteria,which reduces the possibility of an abdominal infection?
Definition
kantrex,neomycin
Term
adverse reaction of aminoglycosides?
Definition
nephrotoxicity,ototoxicity,neurotoxicity,neuromuscualr blockade
Term
drugs used prophylaxis before dental or other procedures in pts allergic to PCN
Definition
macrolides
Term

drugs that are bacteriostatic or bactericidal

-cause changes in protein function & synthesis

Definition
macrolides
Term
high potential for toxicity
Definition
Lincosamides
Term

used to treat from gram - or gram + microorg.

-used for serious infections in which PCN or Erythromycin are not effective

Definition
Lincosamides
Term
bactericidal-interfere with synthesis or bacterial DNA, preventing cell reproduction
Definition
Fluoroquinolones
Term
drugs that is effective against gram - & + microorg.,lower resp infections,bone and joint infections, UTIs, skin infections, and STD
Definition
Fluroquinolones
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