Term
system that consist of bone marrow,blood and blood components |
|
Definition
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|
Term
system that contains lymoh nodes and nodules that destroy pathogens and lymph vessels that return lymph back to the blood |
|
Definition
|
|
Term
what is the function of blood? |
|
Definition
transport of O2,nutrients and cell waste products;regulation of body temp,pH,& fluid balance;production of cells for protection. |
|
|
Term
How many liters of blood does the human body hold? |
|
Definition
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|
Term
Blood cells consist of what? |
|
Definition
|
|
Term
where are all blood cells produced?
|
|
Definition
|
|
Term
where are blood cells found? |
|
Definition
flat bones,irregular bones,long bones |
|
|
Term
liquid portion of blood,transporting medium,important in maintaining body temp. |
|
Definition
|
|
Term
biconcave disks which carry O2 bonded to iron in Hgb,live for 120 days |
|
Definition
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|
Term
lack of iron,Hgb,or RBC's can cause? |
|
Definition
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|
Term
rate of RBC production is most influenced by? |
|
Definition
|
|
Term
what are the 2 most important blood type categories? |
|
Definition
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|
Term
larger than RBC's,involved in immunity or inflammatory response to injury |
|
Definition
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|
Term
formed in the red bone marrow,involved with clotting |
|
Definition
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|
Term
returns tissue fluid to maintain blood volume and protect the body against pathogens and other foreign materials |
|
Definition
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|
Term
masses of lymphatic tissue along the pathways of lymph vessels |
|
Definition
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|
Term
found superficially and deep within the body |
|
Definition
|
|
Term
what are the major paired groups of nodes? |
|
Definition
cervical,inguinal,axillary |
|
|
Term
|
Definition
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|
Term
stores up to 1/3 of the bodys platelets,
not considered a vital organ but if removed a person is more susceptible to certain bacterial infections |
|
Definition
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|
Term
atrophies with increasing age,contains T lymphocytes or T cells |
|
Definition
|
|
Term
What do you assess if pts with hematological disorders? |
|
Definition
abnormal bleeding,petechia,ecchymoses,purpura,fatigue,weakness,
SOB,fever |
|
|
Term
small purplish hemorrhagic spots under the skin |
|
Definition
|
|
Term
larger areas of discoloration from hemmorrhage under the skin |
|
Definition
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|
Term
hemorrhage into the skin,mucous membranes,organs |
|
Definition
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|
Term
what is the nurses role in obtaining a bx? |
|
Definition
-coordinate btw lab & DR
-gather supplies
-admin. analgesic prior to procedure,help pt maintain proper position
-after procedure,observe aspiration site for bleeding and infection
-provide emotional support |
|
|
Term
removal of bone marrow with a needle to be viewed under a microscope |
|
Definition
|
|
Term
what are some common sites used for removal during a bone marrow bx? |
|
Definition
sternum,spinous process of vertebrae,anterior or posterior iliac crest. |
|
|
Term
what are bone marrow bx used to diagnose? |
|
Definition
hematologic disorders,monitor tx,discover tumors,infectious diseases,isolate bacteria/pathogens by culture |
|
|
Term
what are the lab studies that are routinely done for pts with hematologic disorders? |
|
Definition
CBC,total hemoglobin concentration(hgb)hematocrit level(Hct) and platelet level |
|
|
Term
What does coagulation test consists of? |
|
Definition
bleeding times,PT,INR,PTT |
|
|
Term
injection of dye into the lymphatic vessels of the hand or foot.
-X-rays are taken & examined to determine lymph flow or blockages and lymph node involvement |
|
Definition
|
|
Term
needle aspiration or surgical incision to see if enlarged node is caused by infection or malignancy(cancer) |
|
Definition
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|
Term
What are the complications that can occur with blood administration? |
|
Definition
febrile reaction,hypersensitivities,hemolytic reactions (incompatible blood),anaphylactic shock,circulatory overload(rapid transfusion in a short period), death |
|
|
Term
with blood administration in the state of SC, LPNs can only do what? |
|
Definition
assist with proper identification procedures,monitor VS |
|
|
Term
unit of blood should not hang longer than? |
|
Definition
|
|
Term
what size gauge catheter is used with blood administration? |
|
Definition
|
|
Term
during blood administration, only use ___________ to flush line |
|
Definition
|
|
Term
|
Definition
|
|
Term
Decrease in RBC's is due to? |
|
Definition
1. imparied production of RBC's
2. Increased destruction of RBC's
3. Massive or chronic blood loss |
|
|
Term
what is essential for the production of RBCs |
|
Definition
|
|
Term
hereditary anemia in persons from Southeast Asia,Africa,Italy, & Mediterranean islands in which hemoglobin is not synthesized normally |
|
Definition
|
|
Term
|
Definition
red meat,dark green leafy veg.,dried fruits,enriched,fortified, or whole grain products |
|
|
Term
most common nutrient deficiency in the world |
|
Definition
|
|
Term
What are the causes of Iron deficiency Anemia? |
|
Definition
insufficient intake of iron
-excessive blood loss
-lack of stomach acid |
|
|
Term
who is at risk for iron deficiency anemia |
|
Definition
young children,women of childbearing age |
|
|
Term
what can you do to enhance absorption of iron from nonmeat sources? |
|
Definition
consume food rich in Vit C along with iron-rich foods
-stew acidic foods such as tomatoes in iron cookware |
|
|
Term
should be used for several months to help body rebuild iron stores,even if hgb/hct levels return to normal |
|
Definition
|
|
Term
folic acid or vitamin B12 deficiency anemia |
|
Definition
|
|
Term
good food sources of folic acid? |
|
Definition
liver,green leafy veg.,legumes,enriched grain products |
|
|
Term
good food sources of vit B12? |
|
Definition
meat,fish & shellfish,poultry,milk |
|
|
Term
essential for the manufacture of RBC's and for the synthesis and maintenance of myelin |
|
Definition
|
|
Term
continued lack of vit b12 can cause? |
|
Definition
|
|
Term
pts being evaluated for dementia should be checked for? |
|
Definition
|
|
Term
chronic disease that requires Vit B12 injections for life? |
|
Definition
|
|
Term
what are the S&S of anemia? |
|
Definition
pallor,tachycardia,tachypnea,irritability,fatigue,SOB |
|
|
Term
symptoms of anemia occur b/c? |
|
Definition
reduced # of functioning RBC's with reduced ability to carry O2 to tissues |
|
|
Term
What are the symptoms of pernicious anemia? |
|
Definition
numbness of hands & feet;weakness;sore,beefy red tongue |
|
|
Term
symptoms of iron deficiency anemia? |
|
Definition
fissures @ corner of mouth,inflamed tongue(glossitis),spoon-shaped fingernails |
|
|
Term
What are the Diagnostic Test that are done for anemia? |
|
Definition
CBC,Hgb & Hct,serum iron,ferritin,total iron-binding capacity measurements,serum folate,bone marrow bx & analysis |
|
|
Term
causes of aplastic anemia? |
|
Definition
congenital,exposure to toxins,chemo meds,use of cardiopulmonary bypass during surgery,certain viral/bacterial infections,autoimmune diseases |
|
|
Term
bone marrow becomes fatty and incapable of production of necessary #'s of RBC's
-RBC's normal in size & shape, not enough to sustain life
-fatal if untreated |
|
Definition
|
|
Term
what are the S&S of aplastic anemia? |
|
Definition
weakness,fatigue,pallor,SOB,HA,tachycardia,heart failure,ecchymoses,petechiae,oozing blood,bleeding into vital organs, infection |
|
|
Term
dignostic test for Aplastic Anemia |
|
Definition
CBC, bone marrow bx,total iron-binding capacity,serum iron level |
|
|
Term
|
Definition
most effective = bone marrow transplant,
-steroids to stimulate production of cells,hormones,colony-stimulating factors |
|
|
Term
inherited anemia where RBC's have a specific mutation that make Hgb very sensitive to O2 changes
-cells change from round to sickle or crescent shaped
-abnormal shape causes the cells to become tangled in BV and organs,resulting in cong.,clumping and clotting |
|
Definition
|
|
Term
how long do sickled cells usually live |
|
Definition
|
|
Term
S&S of sicke cell crisis? |
|
Definition
severe pain,swelling in joints,abdominal pain,hypoxia,priapism in males,renal failure
-repeated crisis may lead to hand-foot syndrome |
|
|
Term
Diagnostic test for sickle cell anemia? |
|
Definition
blood smear,sickledex test,hemoglobin electrophoresis |
|
|
Term
|
Definition
|
|
Term
cause unknown;
overproduction of RBC's,WBC's and platelets.Organs become congested,skin becomes dark,flushed from build up of red cells,can cause thrombosis & occlusion of vessels.
-found in pts over 50 |
|
Definition
polycythemia vera(primary) |
|
|
Term
results of long term hypoxia
-body makes more red cells in response to low O2
-not an actual disorder |
|
Definition
|
|
Term
blood becomes thick with overabundance of RBC's therefore blood can't circulate easily |
|
Definition
|
|
Term
|
Definition
HTN,visual changes,HA,tinnitus,dizziness,panmyelosis (increases RBC,WBC,platelets), bleeding,chest pain,intense itching,abdominal pain due to enlarged spleen & liver, dark flushed complexion |
|
|
Term
diagnostic test for Polycythemia? |
|
Definition
CBC,bone marrow aspiration |
|
|
Term
|
Definition
therapeutic phlebotomy,low dose aspirin,chemo or radiation therapy,encourage activity to prevent thrombus formation, monitor for bleeding, hypovolemia,encourage 3L of H2O,avoid tight clothing,elevating feet to prevent impairment of circulation ,support hose,anti coagulants,anti platelets |
|
|
Term
catastrophic accelerated clotting throughout peripheral BV,clots can no longer be formed, progresses rapidly
-not a disease but a syndrome
-high mortality rate
-can develop after body sustains major trauma |
|
Definition
DIC (disseminated intravascular coagulation) |
|
|
Term
|
Definition
abnormal bleeding,petechiae,ecchymoses,pain & enlargement of joints,N/V,dyspnea,coma,shock,major organ system failure,sever muscle,back & abdominal pain |
|
|
Term
|
Definition
Prolonged PT,PTT
-decreased Hgb & platelet count
-increases fibrin degredation products,BUN, & creatinine levels |
|
|
Term
What are the interventions/care for DIC? |
|
Definition
admin of blood,plasma,platelets,vit K, & clotting factors
-observe for & report signs of bleeding
-avoid trauma
-tx is aimed @ correcting the cause |
|
|
Term
|
Definition
easy bruising of skin,petechiae,blood in urine,black tarry stools,bleeding from nose or gums,increase in vaginal bleeding,new onset of painful joints |
|
|
Term
results for increased platelet destruction by the immune system which increases the risk for bleeding.
-occurs after an acute viral illness
-can be drug induced or assoc. with pregnancy |
|
Definition
Idiopathic Thrombocytopenic Purpura(ITP) |
|
|
Term
|
Definition
thrombocytopenia(petechiae,eechymoses,bleeding from mouth,nose,GI tract,vital organs such as the brain |
|
|
Term
|
Definition
acute ITP usually resovles on its own
-steroids to prolong life of platelets,chemo,removal of spleen,transfusions of blood,platelets,& vit K |
|
|
Term
group of herediatary bleeding disorders resulting from a severe lack of specific clotting factors |
|
Definition
|
|
Term
|
Definition
bleeding results from injury,hemarthrosis(common bleeding into muscle and joints)
repeated episodes cause joint deformities, esp in elbows, knees and ankles which decreases the pts ROM & ability to walk |
|
|
Term
diagnostic test for hemophilia? |
|
Definition
|
|
Term
interventions for hemophilia? |
|
Definition
freq. need to replace clotting factors & blood products
-no cure,pts can live a normal life
-mild hemophilia A can be treated with injection or nasal inhalation of desmopressin
|
|
|
Term
malignant disease of WBC's that affects all ages? |
|
Definition
|
|
Term
immature WBC's are produced explosively in bone marrow,lymoh tissue,& spleen.
-abnormal & unable to fight infection
-Anemia and bleeding become a problem
-UNTREATED = FATAL |
|
Definition
|
|
Term
What are the types of leukemia? |
|
Definition
acute lymphocytic leukemia (ALL)
-acute myelogenous leukemia (AML)
-Chronic lymphocytic leukemia (CLL)
-Chronic myelogenous leukemia(CML) |
|
|
Term
affects children under 15 years-most common cancer in children |
|
Definition
Acute lymphocytic leukemia (ALL) |
|
|
Term
affects pts over 60 years
-poor prognosis |
|
Definition
acute myelogenous leukemia (AML) |
|
|
Term
usually present with sudden onset with high fever, abnormal bleeding from mucous membranes,petechiae , ecchymosis,and easy bruising |
|
Definition
|
|
Term
|
Definition
|
|
Term
affects B & T lymphocytes, occurs in adults over 40 years of age |
|
Definition
Chronic Lymohocytic leukemia (CLL) |
|
|
Term
characterized by the Philadelphia chromosome, affects ages 40-45/older adults |
|
Definition
chronic myelogenous leukemia (CML) |
|
|
Term
|
Definition
low grade fever,weakness,SOB,malaise,fatigue, tachycardia,palpitations,abd pain,sternal pain/rib tenderness,confusion,HAs,personality changes |
|
|
Term
diagnostic test for leukemia? |
|
Definition
CBC but only bone marrow aspiration can confirm diagnosis |
|
|
Term
interventions for leukemia? |
|
Definition
chemo,radiation,bone marrow transplant |
|
|
Term
deadly cancer of plasma cells in bone marrow
-bony destruction & pathological fx
-silent & deadly
often affects men 50-70
-cause unknown-poor prognosis |
|
Definition
|
|
Term
|
Definition
Skeletal pain-common complaint
-severe back & rib pain,achiness of long bones,joint swelling & tenderness,risk of hypercalcemia,susceptible to infection,anemia,kidney failure |
|
|
Term
diagnostic test for multiple myeloma |
|
Definition
CBC,X-rays,urine studies,bone marrow bx,IVP |
|
|
Term
|
Definition
steroids,chemotherapy,thalidomide,aredia,velcade,external beam irradiation,laminectomy,dialysis,combo of high dose chemo. & stem cell transplantation,keep mobile(physical therapy) |
|
|
Term
lymphoma or cancer of the lymph system
-distinguishing factor-presence of Reed-Sterberg cell
-most prevalen in men-young adult ages 15-40
-most curable type of lymphoma |
|
Definition
|
|
Term
what confirms the dianosis of hodgkin's disease? |
|
Definition
bx of enlarged nodes for Reed-Sternberg cell |
|
|
Term
S&S of hodgkin's disease? |
|
Definition
painless swelling of lymph nodes,pruritis,alcohol-induced pain,persistent low-grade fever,night sweats,fatigue,wt loss |
|
|
Term
diagnostic test for hodgkins disease? |
|
Definition
lymph node,bone marrow,liver & spleen bx,CXR,abd CT scan,CBC, Management of symptoms |
|
|
Term
therapeutic measures/management for hodgkins disease? |
|
Definition
|
|
Term
all other types of lymphomas with absence of Reed-Sternberg cell
-arise from B cells & T cells |
|
Definition
|
|
Term
S&S of non-hodgkins lymphomas |
|
Definition
enlarged,painless,rubbery nodes,similar symptoms to HD |
|
|
Term
diagnostic test for Non Hodgkins lymphoma
|
|
Definition
bx of lymph nodes,various scans,CXR,CBC,liver function studies |
|
|
Term
therapeutic measures/management for non hodgkins lymphomas? |
|
Definition
chemo,radiation,stem cell transplant,interferon therapy to boost immune system to fight the cancer,monoclonal antibodies to targe tand destroy cancer cells,manage symptoms |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
removal of the spleen makes a person more? |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
strong membranes that enclose individual muscles |
|
Definition
|
|
Term
|
Definition
|
|
Term
break down & reabsorb bone when calcium is needed in blood;reshape bone after fxs |
|
Definition
|
|
Term
fluid filled sac--permits easy sliding as the joint moves |
|
Definition
|
|
Term
grating sound as a joint or bone moves |
|
Definition
|
|
Term
swollen synovial tissue within the joint |
|
Definition
|
|
Term
needed for the absorption of calcium and phosphorus from food? |
|
Definition
|
|
Term
released by parathyroid gland-increases the removal of Ca and phosphate from bones |
|
Definition
|
|
Term
produced by thyroid gland-promotes retention of calcium in bones |
|
Definition
|
|
Term
important for retention of calcium in adult bones |
|
Definition
|
|
Term
when nerve impulses arrive @ the neuromuscular junction, what is released? |
|
Definition
|
|
Term
binds to receptors on sarcolemma;electrical impulse is generated;muscle fiber shorten,muscle contracts |
|
Definition
|
|
Term
What happens to calcium & phosphorus levels in a Thyroid or Parathyroid gland disorder? |
|
Definition
either Ca increases & phosphorun decreases
-or Ca decreases & Phosphorun increases |
|
|
Term
what happens to Alkaline Phosphatase (ALP) levels when a bone is damaged or has an abnormality? |
|
Definition
|
|
Term
What cardiovascular condition might be diagnosed by an increase in Myoglobin-a protein found in skeletal and cardiac muscle that causes red color of the muscle? |
|
Definition
|
|
Term
what happens to muscle enzyme levels when muscle is damaged? |
|
Definition
going to be elevated when damage to muscle |
|
|
Term
serious fatal condition assoc. w/ muscle distruction due to fever,injury,convulsions,or prolonged muscle compressions |
|
Definition
|
|
Term
grating sound as a joint or bone moves |
|
Definition
|
|
Term
excessive stretching of ligaments |
|
Definition
|
|
Term
ends of the bones(joints) are forced from their normal position |
|
Definition
|
|
Term
occurs when a muscle or tendon is excessively stretched |
|
Definition
|
|
Term
inflammation of bone,especially the marrow,caused by a pathoenic organism |
|
Definition
|
|
Term
swollen synovial tissue within the joint |
|
Definition
|
|
Term
condition in which bone tissue dies as a result of impaired blood supply |
|
Definition
|
|
Term
what is the tx of bone & soft tissue disorders |
|
Definition
RICE(rest,ice,compression,elevate) |
|
|
Term
how is carpal tunnel syndrome diagnosed? |
|
Definition
its diagnosed by a positive Phalen's test |
|
|
Term
tx of carpal tunnel syndrome |
|
Definition
splints,NSAIDS,cortisone injection,surgery |
|
|
Term
|
Definition
|
|
Term
fx that does not break skin? |
|
Definition
|
|
Term
fx where bone in 2 pieces,can cut blood vessels and nerves |
|
Definition
|
|
Term
What are complications of fx? |
|
Definition
impaired neurovascular status,hemorrhage,infection & thromboembolitic (fat embolism) |
|
|
Term
|
Definition
increase calcium,fall prevention |
|
|
Term
what happens if a cast is too tight? |
|
Definition
can interfere with skin integrity & cause compartment syndrome |
|
|
Term
How does the Dr loosen the cast? |
|
Definition
bivalve the cast with a cast cutter to relieve pressure & prevent pressure necrosis of the underlying skin |
|
|
Term
how do you handle a wet cast? |
|
Definition
palm of the hands to prevent making indentations in the plaster that could become pressure points |
|
|
Term
rounding the edges of the cast to ensure that all the rough edges are properly covered |
|
Definition
|
|
Term
what should you teach a pt about cast care? |
|
Definition
instruct pt not to cover cast while it is drying (24-72 hrs).
-make sure pt knows to keep cast dry when bathing
-never place an object inside the cast |
|
|
Term
what are the components of a neurovascular assessment? |
|
Definition
color,temp,pain,movement,sensation,pulses,capillary refill |
|
|
Term
sheaths of fibrous tissue that support & partition nerves,muscles,& BV,primarily in the extremities
-pressure within one or more extremity compartments increases,causing massive circulation impairment to the area.
- cast or bulky dressings can increase the pressure |
|
Definition
ACS-acute compartment syndrome |
|
|
Term
S&S of acute compartment syndrome |
|
Definition
severe increasing pain that is not relieved with narcotics & occurs more on active movement than passive movement |
|
|
Term
what would you teach a pt who has osteoporosis? |
|
Definition
increase calcium intake,weight bearing exercise |
|
|
Term
what would you teach a pt with systemic lupus erythematosus? |
|
Definition
skin care,exercise,immunizations against specific infections |
|
|
Term
what would you teach a pt with RA? |
|
Definition
help pt plan a daily schedule that balanced rest & exercises |
|
|
Term
what would you teach a pt who has osteoarthritis? |
|
Definition
needs to avoid exposure to the cold and person with infections.
-Movement makes worse |
|
|
Term
what would you teach a pt who has gout? |
|
Definition
should avoid all forms of aspirin & diuretics b/c they can trigger attacks.
-increase daily fluid intake to prevent kidney stones,avoid alcohol,should avoidhigh purine(protein) foods such as organ meats,shellfish,and oily fish |
|
|
Term
what should you teach a pt with paget's disease? |
|
Definition
teach pt about the disease,medication and other therapies |
|
|
Term
chronic,progressive,systemic inflammatory disease.
-destroys synovial joints & other connective tissues.
-includes major organs.
affects women 3x more than men |
|
Definition
|
|
Term
|
Definition
bilateral,symmetrical joint inflammation,stiffen after resting,activity decreases pain & stiffness,low grade fever,weakness,fatigue,anorexia |
|
|
Term
|
Definition
joint deformity,secondary osteoporosis |
|
|
Term
|
Definition
unknown,genetic predisposition,environmental,autoimmune response-antibodies(called Rheumatoid Factor)
local and systemic inflammation |
|
|
Term
what makes the condition of RA better? |
|
Definition
activity decreases pain
-heat/cold
-balanced rest & activity
-surgery-total joint replacement |
|
|
Term
also known as degenerative joint disease
-articular cartilarge/joints bone ends deteriorate
-joint space narrows
-wt bearing joints affected so obesity worsens it |
|
Definition
|
|
Term
|
Definition
joint pain,intensifies after physical activity,stiffness,heberden's & bouchard's nodes,bony nodes on joints of fingers |
|
|
Term
what makes osteoarthritis better? |
|
Definition
NSAIDs,rest,activities scheduled when pain is low,heat or cold,wt control,complementary therapies,imagery,music therapy,acupressure,acupuncture,surgery,total joint replacement,topical capsaicin cream |
|
|
Term
skin traction.
-indicated for pts with hip fxs and is frequently applied to prevent further trauma while the pt is waiting for surgery
-used for the releif of painful muscle spasm |
|
Definition
|
|
Term
balanced suspension traction
-skeletal traction
-aligns bones |
|
Definition
balanced skeletal traction |
|
|
Term
what is important to teach a pt who is having a Total hip replacement? |
|
Definition
keep leg abducted with pillows
-bending @ the waist cant be greater than 90 degrees
-getting up from a sitting position requires pushing straight up off of the chair or bed without leaning fwd
-walkers can be used to assist walking
-physiotherapy and occupational therapy can provide equp. that aids in putting on socks & shoes |
|
|
Term
what should be assessed post op after a hip replacement? |
|
Definition
monitor pt positioning,skin breakdown, |
|
|
Term
how should you care for a traumatically amputated body part? |
|
Definition
wrap it in a cool slightly moist cloth & place it in a sealed bag
-the bag may be submerged in cold water until the body part is transported to the hospital |
|
|
Term
what is important in caring for an amputee in the first 24 hrs? |
|
Definition
assess for hemorrhage,infection,dcheck for mobility & ambulation
-elevate to reduce swelling but not greater than 24 hrs due to risk of flexion contracture of hip: no sitting with hip felxed for long periods |
|
|
Term
how should a stump dsg be applied? |
|
Definition
wrapped at least every 8 hrs using an elastic wrap in a figure eight fashion. |
|
|
Term
why is a figure 8 stump dsg importnat? |
|
Definition
helps to mold the stump for prosthesis |
|
|
Term
skeletal muscle fibers degenerate & atrophy & are replaced by connective tissues |
|
Definition
|
|
Term
build up of uric acid in the body
-attack causes severe pain and inflammation in one or more small joints |
|
Definition
|
|
Term
autoimmune disease-body attacks itself with abnormal antibodies that form immune complexes that lodge in blood & organs & affect the body's connective tissue |
|
Definition
systemic luput erythematosus |
|
|
Term
S&S of systemic lupus erythematosus |
|
Definition
butterfly rash,photosensitive |
|
|
Term
caused by an autoimmune response in which inflammation develops into fibrosis (scarring) & sclerosis(hardening) of tissues |
|
Definition
|
|
Term
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Definition
arthritis,fatigue,pitting edema,tightening,hardening,thickening of skin tissue,loss of ROM,contractures,internally can affect kidneys,lungs,heart,GI tract |
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