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Oct. 13 Lecture
part 2
30
Nursing
Graduate
10/15/2014

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Term
IS THE PRESSURE-VOLUME LOOP SUPERIMPOSED WITHIN THE ACTIVE AND PASSIVE TENSION CURVE OF CARDIAC MUSCLE?
Definition
YES
Term
IN PHASE 1 OF THE PRESSURE VOLUME LOOP WE HAVE AN INCREASE IN VOLUME, BUT A SMALL INCREASE IN PASSIVE LEFT VENTRICULAR PRESSURE. WHAT PHASE IS THIS CALLED?
Definition
DIASTOLE
Term
AN INCREASE IN LEFT VENTRICULAR PRESSURE WITH NO CHANGE IN LEFT VENTRICULAR VOLUME IS KNOWN AS WHAT PHASE?
Definition
PHASE 2. THE ISOMETRIC CONTRACTION
Term
WHAT OCCURS BETWEEN PHASE 1 AND PHASE 2?
Definition
CLOSURE OF AV VALVES
Term
ON THE X AXIS, THE MAXIMUM AMOUNT OF VOLUME THAT THE VENTRICLE IS FILLED WITH AT THE END OF DIASTOLE IS KNOWN AS WHAT?
Definition
THE PRELOAD.
Term
WHAT OCCURS AT THE END OF THE ISOMETRIC CONTRACTION PHASE? IN OTHER WORDS WHAT VALVE OPENS?
Definition
AORTIC VALVE OPENS
Term
IF VOLUME IS THE X AXIS WHAT IS THE Y AXIS?
Definition
PRESSURE WHICH IS AFTERLOAD
Term
WHY IS EJECTION NOT AN ISOTONIC CONTRACTION?
Definition
THE PRESSURE IS INCREASING AND THE VOLUME IS DECREASED. WE CALL THIS SYSTOLE
Term
WHAT IS THE PEAK AT THE TOP OF PHASE 3?
Definition
MAXIMAL SYSTOLIC PRESSURE.
Term
WHY IS DICROTIC NOTCH NOT PRESSURE ON THE PRESSURE VOLUME LOOP?
Definition
BECASUE IT'S IN THE VENTRICLE, NOT THE AORTA.
Term
WHAT IS HAPPENING DURING ISOVOLUMETRIC RELAXATION IN RELATION TO PRESSURE AND VOLUME?
Definition
DECREASE IN LVP AND NO CHANGE IN LV VOLUME.
Term
HOW IS SYSTOLE AND DIASTOLE DEFINE?
Definition
AS CHANGES IN VENTRICULAR VOLUME WHICH MEANS THAT THE ISOVOLUMETRIC PHASES ARE NEITHER SYSTOLIC NOR DIASTOLIC BECAUSE THE VOLUME IS NOT CHANGING.
Term
WHAT IS THE DIFFERENCE FROM A LEFT VENTRICULAR AND RIGHT VENTRICULAR PRESSURE VOLUME LOOP?
Definition
THE VOLUMES ARE THE SAME BUT THE PRESSURE DIFFER.
Term
BETWEEN WHAT PHASES IS LVESV MEASURED?
Definition
EITHER AT THE END OF PHASE 3 TO THE BEGINNING OG PHASE I. THE VOLUME IS THE SAME FOR THESE.
Term
WHAT ARE 2 WAYS TO INCREASE STROKE VOLUME?
Definition
INCREASE IN LVEDV (PRELOAD) OR DECREASE IN LVESV (AFTERLOAD)
Term
WHAT IS THE LIMITATION WITH THE VOLUME PRESSURE LOOP MODEL?
Definition
HR IS NOT PRESENT. IT IS ALSO HARD TO DETECT CONTRACTILITY.
Term
WHAT IS THE TERM FOR ANY MECHANISM THAT, AT CONSTANT MUSCLE LENGTH (CONSTANT PRELOAD), SHIFTS THE FORCE VELOCITY CURVE TO THE RIGHT?
Definition
CONTRACTILITY (+DP/DT). IF THE MUSCLE LENGTH CHANGES THE PRELOAD CHANGES, THAT IS IMPORTANT.
Term
WHAT IS THE TERM FOR THE INTRINSIC ABILITY OF MYOCARDIAL CELLS TO DEVELOP FORCE AT A GIVEN CELL LENTH (INDEPENDENT OF ANS)?
Definition
PRELOAD. ITS THE AMOUNT OF ACTIN AND MYOSIN OVERLAP. PRELOAD- THE STARTING LENGTH DETERMIENS THE FORCE OF CONTRACTION. THAT'S FRANK-STARLING.
Term
WHAT IS ANOTHER NAME FOR CONTRACTILITY?
Definition
INOTROPY
Term
HOW IS THE CHRONOTROPHY EFFECTS?
Definition
BY THE SA NODE
Term
WHAT IS DRONOTROPHY?
Definition
CONDUCTION OF NERVE IMPULSES
Term
WHAT IS LUSITROPHY?
Definition
HOW FAST DOES THE VENTRICULE LOSES PRESSURE, OR HOW FAST IT RELAXES.
Term
IF PRELOAD IS INCREASED WHAT HAPPENS TO THE VELOCITY OF CONTRACTION?
Definition
IT INCREASES
Term
AT ANY GIVEN AFTERLOAD, IF I INCREASE THE PRELOAD, THE VELOCITY OF SHORTENING WITH DO WHAT?
Definition
INCREASE. IT WILL SHORTEN MORE QUICKLY.
Term
DOES AN INCREASE IN PRELOAD INCREASE IN VMAX?
Definition
NO. PRELOAD INCREASES VELOCITY OF CONTRACTION, BUT PRELOAD DOES NOT INCREASE V-MAX.
Term
WHAT DOES CONTRACTILITY DO TO VMAX?
Definition
IT INCREASES IT!
Term
WHAT TYPES OF DYSFUNCTION IS A PATIENT WHO HAD AN MI GOING TO DEVELOP?
Definition
SYSTOLIC AND DIASTOLIC
Term
WHAT IS THE PROBLEM WITH SCAR TISSUE?
Definition
IT IS NON-COMPLIANT. IT DOESN'T CONTRACT ON IT'S OWN.
Term
HOW WOULD YOU DESCRIBE SYSTOLIC DYSFUNCTION?
Definition
SCAR TISSUE ON THE VENTRICLES POST MI THAT ISN'T ABLE TO GET BLOOD OUT BECAUSE THE SCAR TISSUE ISN'T COMPLIANT AND DOESN'T CONTRACT ON IT'S OWN.
Term
HOW WOULD YOU DESCRIBE DIASTOLIC DYSFUNCTION?
Definition
NOT ABLE TO GET THE BLOOD INTO THE VENTRICLE DUE TO SCAR TISSUE.
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