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agout-protein; neuropeptide Y |
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effects on MC1R receptor, decreases food intake and increases energy expenditure |
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antihistamines, antiepileptics, antihypertensives, antidepressants, corticosteroids, diabetic, antipsychotics |
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Definition
Associated with weight gain |
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exercise: 30-45 minutes, 3-5 days per week |
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exercise: 30 or more minutes, most, if not all days of the week |
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Inhibits fat absorption from intestines, inhibitor of pancreatic enzyme, lipase |
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5-HT2C receptor agonist: anorexigenic (decreases food consumption and promotes satiety) |
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AE include nausea, dry mouth, nausea, dizzness, headache, vomiting, fatigue, urinary tract infections |
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FDA approved for long-term use |
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Orlistat (Xenical) and Phentermine-topiramate (Qsymia) |
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Lack of long term efficacy; hypertension, toxicity |
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Stimulants (ex. Phentermine) |
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Addresses obsessive impulsive aspect of eating disorders- |
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suppresses appetite via 5HT2C antagonistic properties |
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also may be used in obesity |
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Metformin, Anticonvulsants |
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synthetic peptide hormone; modulates gastric emptying, prevents postprandial risk in plasma glucagan = satiety; being tested for obesity |
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CB1 Receptor antagonist thought to suppress appetite; withdrawn NDA for weight management; suicide ideation and other psychiatric symptoms |
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complications include infection, DVT, wound deshicense, anastomotic leaks... irritable bowel syndrome can lead to rectal problems |
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