Term
| white, flat skin lesion of vagina with hydropic basal cells and epidermal thinning |
|
Definition
|
|
Term
| white, flat skin lesion of vagina with epidermal thickening and hyperkeratosis |
|
Definition
| squamous cell hyperplasia |
|
|
Term
| which leukoplakia increases risk for squamous cell carcinoma? |
|
Definition
|
|
Term
| multinucleated giant cells; red papules that become vesicles and then ulcers; dx? |
|
Definition
|
|
Term
| koilocytes and verrucous lesions on vulva; dx? |
|
Definition
|
|
Term
| which HPV strains cause warts? which ones cause cervical cancer? |
|
Definition
| warts: 6, 11. cancer: 16, 18 |
|
|
Term
| VIN, CIN, and VAIN are all graded similarly, I-III. What are I, II, and III characterized by? |
|
Definition
| I. lower third shows atypia. II. middle third shows atypia. III. full thickness atypia. |
|
|
Term
1. classic VIN gives rise to...
2. differentiated VIN gives rise to... |
|
Definition
1. classic -> invasive basaloid or warty carcinoma
2. differentiated -> invasive keratinizing squamous cell carcinoma |
|
|
Term
| atypia of only basal layer; classic or differentiated VIN? |
|
Definition
|
|
Term
| vaginal squamous cell carcinoma is associated with classic VIN/differentiated VIN/both |
|
Definition
| both: 70% associated with differentiated VIN; 30% associated with classic VIN |
|
|
Term
| vulva shows red, crusty lesion with irregular margins; large tumor cells with a clear halo of mucin; dx? |
|
Definition
| extramammary Paget's disease |
|
|
Term
| T/F: extramammary Paget's disease is associated with an underlying carcinoma |
|
Definition
| False. (Paget's disease of the *breast* is associated with underlying carcinoma.) |
|
|
Term
|
Definition
|
|
Term
| how do you diagnose VAIN? |
|
Definition
| colposcopic exam with 5% acetic acid |
|
|
Term
| what is the most common cancer of the vagina? |
|
Definition
|
|
Term
| vaginal biopsy shows Cambium layer, clear zone; dx? |
|
Definition
| embryonal rhabdomyosarcoma |
|
|
Term
| vaginal biopsy shows cells with cytoplasmic tails and striations; grape-like masses fill endometrial cavity; dx? |
|
Definition
| vagina: embryonal rhabdosarcomyoma |
|
|
Term
| at what age does embryonal rhabdomyosarcoma present? |
|
Definition
|
|
Term
|
Definition
| young age at first sexual intercourse, multiple partners, promiscuity of male partner, unprotected intercourse |
|
|
Term
| what cells does HPV infect? what cells does HPV multiply in? |
|
Definition
| infects immature cells of squamou-columnar junction; multiplies in mature cells |
|
|
Term
| Pap shows large cells but few; which CIN grade is this? |
|
Definition
|
|
Term
| post-coital or abnormal bleeding with foul smelling vaginal discharge; dx? |
|
Definition
| cervical squamous cell carcinoma |
|
|
Term
|
Definition
| cervical adenocarcinoma (malignant glandular tissue) |
|
|
Term
[image]
what phase of menstrual cycle is this? |
|
Definition
|
|
Term
[image]
what phase of the menstrual cycle is this? |
|
Definition
|
|
Term
[image]
what phase of the menstrual cycle is this? |
|
Definition
|
|
Term
| common site of endometriosis that causes infertility |
|
Definition
| ovaries or Fallopian tube |
|
|
Term
|
Definition
| endometriosis in ovaries (chocolate cyst) |
|
|
Term
| what theories are proposed for the pathogenesis of endometriosis? |
|
Definition
| retrograde menstruation (metastatic), peritoneal metaplasia to endometrial tissue, or vessels/lymphatics deposit endometrial tissue to ectopic sites |
|
|
Term
| enlarged, globular uterus; pt presents with pelvic pain, dysmenorrhea, menorrhagia; dx? |
|
Definition
|
|
Term
1. stroma and glands outside the uterus
2. stroma and glands in myometrium |
|
Definition
1. endometriosis
2. adenomyosis |
|
|
Term
1. increased glands:stroma ratio; cystically dilated; dx?
2. increased gland:stroma ratio; glandular crowding; dx? |
|
Definition
1. simple endometrial hyperplasia
2. complex endometrial hyperplasia |
|
|
Term
| preceded by endometrial hyperplasia; pt is obese, infertile, late menopause; pathogenesis involves high estrogen stimulation; dx? |
|
Definition
| endometrial adenocarcinoma type I |
|
|
Term
| preceded by endometrial atrophy; biopsy shows papillae and psammoma bodies; dx? |
|
Definition
| endometrial adenocarcinoma type II |
|
|
Term
1. which endometrial adenocarcinoma is more aggressive?
2. presents earlier?
3. more common? |
|
Definition
1. type II
2. type I
3. type I |
|
|
Term
| what is the most common subtype of endometrial adenocarcinoma type II? |
|
Definition
|
|
Term
| biopsy shows a sea of many small cells; these can form tumors with "pushing" or "infiltrating" margins; dx? |
|
Definition
| endometrial stromal tumors |
|
|
Term
| diagnostic criteria for a MMMT |
|
Definition
| MMMT = Malignant Mixed Mullerian Tumor = carcinosarcoma; requires both atypia of epithelia and stroma. |
|
|
Term
|
Definition
heterologous: with extra-uterine tissue
homologous: uterine tissue only |
|
|
Term
| which leiomyoma subtype can present with bleeding? |
|
Definition
|
|
Term
| well-circumscribed, pearly white tumors with whorled fascicles of smooth muscle; dx? |
|
Definition
|
|
Term
| biopsy shows zonal coagulative necrosis; can spread to lungs; 5y survival rate is 40%; dx? |
|
Definition
|
|
