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OB Exam 3 Final
Final OB exam
219
Nursing
Undergraduate 4
04/08/2012

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Term
Magnesium Sulfate
Definition
Used for the treatment of preeclampsia

Bolus of 6g magnesium sulfate is administered IV over 20-30 minutes to prevent seizure

Ad additional bolus of 2g of magnesium over 5-10 minutes can be given
Term
Antidote to Magnesium Sulfate
Definition
Calcium Gluconate
Term
Side effects of Loading dose of Magnesium Sulfate
Definition
Warmth, headache, nystagmus, nausea, dry mouth, dizziness, lethargy, risk of pulmonary edema
Term
Fetal Side effects of Magnesium Sulfate
Definition
Hypotonia, lethargy, hypoglycemia, hypocalcemia
Term
Management of Magnesium Sulfate
Definition
Monitor serum levels as ordered, monitor respirations (should not be below 12/min), monitor BP, assess DTR, monotor Urine output (no less than 30 mls an hour)
Monitor fetal heart tones continously
Monitor neuro status
Term
Abortion
Definition
pregnancy termination priorto 20 weeks or with a fetus weighing less than 500 grams. Abortion can be spontaneous or induced. Miscarriage is another term for a spontaneous abortion.
Term
Threatened abortion
Definition
Unexplained bleeding cramping, backache that indicates that the fetus may be in jeopardy.
Term
Imminent abortion
Definition
Bleeding or cramping increases and the internal cervical os dilates or membranes may rupture.
Term
Complete abortion
Definition
All the products of conception are expelled.
Term
Missed Abortion
Definition
The fetus dies in the utero but is not expelled- give methergine or methotextrate for induction
Term
Treatment for spontaneous abortion
Definition
Bed rest, abstinence from coitus, D&C or suction evacuation, Rh immune globulin because don't want Inti D antigen to attack next pregnancy.
Term
Spontaneous abortion nursing care
Definition
Assess the amount and appearance of any vaginal bleeding, monitor vital signs and degree of discomfort, assess need for RH immune globulin, assess fetal heart rate, assess the responses and coping of the woman and her family
Term
Post abortion education
Definition
Bleeding due to placenta detaching from the wall, cramping for 1-2 weeks, vaginl rest for 1 week, monitor temp. BID 100.4 too high, follow up in 2 weeks
Term
Premature dilation of the cervix
Definition
Painless dilation before pregnancy comes to term leading to early expulsion of fetus, congenital, acquired, biockemical, hormonal, DES, anatomical.
S&S- advanced cervical dilation, low abd pressure, bloody show, urinary frequency, fetus could have some lightening
Term
Cervical Incompetence Treatment
Definition
Serial cervical ultrasound assessments, bed rest, progesterone supplementations (inhibits myometrial contractions), antibiotics, anti-inflammatory drugs, cerclage procedure
Term
Cerclage
Definition
Suture remaed at term (37 weeks) or may leave in place and have C/S if planning future pregnancies.
Should not have beeding after procedure
Report signs of infection or pain
Term
Ectopic Pregnancy
Definition
Implantation of zygote in other than the endometrial lining of uterus, risk factors: tubal damage, scarring, endometriosis, previous ectopic, IUD, PID, tube anomalies, smoking, ovulation inducing drugs, advanced maternal age, douching
Term
Symptoms of an Ectopic Pregnancy
Definition
Amenorrhea, breast tenderness, nausea, presence of hCG, slowly incresing B-hCG levels, Fainting/Dizziness with rupture, referred right shoulder pain, Low Hct/Hgb, increased leukocytes, no gestational sac on US
Term
Treatment of Ectopic Pregnancy
Definition
Methotrexate may be used if extopic pregnancy is unruptured and of 3.5cm size or less

Methotrexate is a folicacid antagonist
Alternate dose of methotrexate or leucovorin
Surgery (removal of tube may be indicated)
Rh immune globlin
Term
Management of Ectopic Pregnancy
Definition
Assess for signs of shock, increased HR, hypotention, Pallor, decreased Urinary output, Assess vaginal bleeding, pain, I/O, emotional status, post-op care
Term
Gestational Tropoblastic Disease (Hydatiform Mole)
Definition
Complete mole- fetilization of egg with no nucleus- looks like white grapes
Results in nucleus of sperm duplicating itself, or 2 sperm fertilize ovum with no nucleus. No fetus, placenta, amniotic membranes, no placenta to recieve maternal blood so hemorrhage into uterine cavity and bag. bleeding occurs.

Partial mole- 2 sperm fertilize one ovum
Gestational trophoblastic neoplasia- 20% choriocarcinoma--- heta Hcg levels do not fall chemotherapy is required
Term
Gestational trophoblastic disease symptoms
Definition
Vaginal bleeding (looks like prune juice), cramping, passing of hydropic vesicles, uterine enlargement greater than expected for gestational age, uterine enlargement greater than expected for gestational age, absence of fetal heart sounds, higher than anticipated hCG levels, increased nausea and vomiting.
Term
Gestationald Trophoblastic disease treatment
Definition
Immediate evacuation of mole, follow up HCG levels for at least 6 months to detect trophoblastic peoplasia,careful follow up, no pregnancy for one year.
Term
Gestational Trophoblastic disease nursing care
Definition
Monitor vital signs, monitor vaginal bleeding, assess abdominal pain, assess the woman's emotional state and coping ablity, risk for hypovolemic shock
Term
Hyperemesis Gravidarum
Definition
Presents with severe nausea and vomiting such that it affects nutirtional status and hydration (losing weight)
Risks- dehydration, electrolyte imbalance, acidosis, weight loss, ketonuria, and hepatic or renal damage

Prevalence- nulliparous women, adolescents, multiple gestation, increased body weight, gestational trophoblastic disesase.
Term
Hyperemesis Gravidarum Treatment
Definition
Obscure etiology due to high levels of hCG
Treatment- Control vomitting, IV therapy to prevent dehydration (dextrose solution), resotre electrolyte imbalanace, maintain adequate nutrition, eat small meals throughout the day.
Pyridoxine (Vitamin B6) PO 10mg-25mg three times a day
Phenergan IM
Reglan
Zofran
Term
Hypertensive Disorders
Definition
Preeclampsia-eclampsia, Chronic hypertension, chronic hypertension with superimposed preeclampsia, Gestational hypertension
Term
Preeclampsia
Definition
Defined as an increase in blood pressure after 20 weeks gestation, accompaned by proteinuria, occurs in a previously normotensive women
Term
Eclampsia
Definition
The occurrence of a seizure in a woman with preeclampsia who has no other cause for seizure
Term
Preeclampsia Disease Theories
Definition
Impaired trophoblast differentiation and invasion, placental and edotheilial dysfunction, an immune reaction to paternal antigens, exaggerated systemic inflammatory response, may be related to an imbalance between circulating angiogenesis related factors.

The placental plays a central role in the development of the disease and the only known cure isthe birth of the fetus and removal of the placenta.
Term
Characteristics of Preeclampsia
Definition
Maternal vasospasm resulting in decreased perfusion to all organs including the placenta, decrease in plasma volume, activation fot eh coagulation cascade, alteration in glomerular capillary endothelium
Term
Pathophysiology of Preeclampsia
Definition
Maternal vasospasm, decreased perfusion to virtually all organs
Renal- glomerular endotheilial damage, fibrin depsots leading to ischemia leading to decreased GFR. Protein is excreted in the urine, uric acid, creatinine, andcalcium clearance are decreased, Oliguria develops as condition worsens.

Hepatic- increased microvascular fat deposits in the liver, may cause epigastric pain, liver damage may be mild or may leat to HELLP
May have periportal hemorrhagic necrosis which can lead to subscapsular hematoma (RUQ pain)
Term
Pathophysiology of Preeclampsia
Definition
Leakage of serum protein into extracellular spaces and into urine results in creased serum lbumin and tissue edema.
Neurological- endothelial damage to brain results in fibrin deposition, edema, cerebral hemorrhage, may lead to hyperfexia and severe headaches.
Retinal- arteriospasms may cause blurring or double vision, photophobia, or scotoma.
Coagulation- Activated in preeclampsi, thrombocytopenia- 2/2 increased platelet aggergation and deposits at sites of endolthelial damage, activating the clotting cascade
Term
Assessment findings of preeclampsia
Definition
HTN >140/90
Proteinuria 1+ or greater
Brisk DTR, Clonus
HA unrelieved by Tylenol, visual changes, epigastric pain, edema
Term
Management of Severe Preeeclampsia
Definition
Bed Rest, treatment with magnesium sulfate, corticosteroids, fluid and electrolyte replacement, antihypertensive therapy (Hydralizine), Delivery
Term
Home management of preeclampsia
Definition
Monitor for signs and symptoms of worsening condition, fetal movement counts, frequent rest in the left lateral position, monitoring of blood pressure, weight, and urine protein daily, NST, laboratory testing
Term
Signs and Symptoms of eclampsia
Definition
Seizure, severe persistent HA, epigastric pain, N/V, hyperflexia with clonus, restlessness thought to be triggered by cerebral vasospasm, cerebral hemorrhage, cerebral ischemia, cerebral edema
Term
Care during a seizure
Definition
Remain with patient, call for help, safety- assess airway and breathing, lower HOB and turn head to side if possible, anticipate the need to suction, Record time, length, type or seizure activity, notify physician, prevent maternal injury (padded side rails)
Term
Management of eclampsia
Definition
Assess characteristics of seizure, assess status of the fetus, assess for signs of placental abruption, maintain airway and oxygenation, position on side to avoid aspiration, suction to keep the airway clear, administer magnesium sulfate
Term
HELLP syndrome
Definition
Hemolysis, elevated liver enzymes, and low platelet count
Associated with severe preeclampsia
Hypertension and proteinuria may be absent
90% of women present with symptoms before 36 weeks
25% first demonstrate the disease in the PP period
Term
HELLP syndrome pathophysiology
Definition
Microangiopathic hemolytic anemia- RBC are distored or fragmented during passage through small damaged vessels.
Vascular damage is associated with vasospasm and platelets aggregate at sites of camage, resulting in low platelet count.
Elevated liver enzymes occur from blood flow that is obstructed due to fibrin deposits.
Epigastric pain due to the increase in hepatic pressure causes swelling of the liver.
Hyperbilirubinemia and jaundice may occur.
Liver may rupture.
Term
Symptoms of HELLP
Definition
Hemolysis, elevated liver enzymes, low platelets- thrombocytopenia, N/V, epigastric pain
Term
Chronic Hypertension
Definition
Chronic hypertension exists when the blood pressure is 140/90 or higher before pregnancy or before the 20th week of gestation.
Persists 42 days following childbirth
Term
Chronic Hypertension Management
Definition
Nutrition, bed rest, medications, prenatal visits, blood pressure monitoring, fetal surveillance
Term
Gestational Hypertension
Definition
Exitsts when transient elevation of blood pressure occurs for the first time after midpregnancy witout proteinuria or other signs of preeclampsia.
If preeclampsia does not occur and if BP returns to normal 12 weeks PP it is diagnosed to be gestaional hypertension.
Term
RH Alloimmunization
Definition
Rh-negative person is exposed to a Rh-positive blood an antigen-antibody response occurs.
Antibodies are formed, person can be sensitized.
Antigens in the D group are usually involved with incompatiblity between the mother and the fetus.
6 in every 1000 live births is complicated by maternal sensitization to the D red cell antigen.
Screenin for the D antigen is recommended.
Term
RH immune globulin
Definition
Resulted in a marked decrease in prevalence of alloimmunization to the RhD in pregnancy.
During pregnancy small amounts of fetal blood may cross he placenta.
Rh-negative mother whose fetus is Rh-positive my develop anti-D antibodies.
During delivery larger amounts of fetal blood can enter the mom's body.
After exposure to the Rh-positive antigen the primary immune response is the development of immunoglobulin M (IgM) antibodies.
The primary response develops slowly over several weeks with a detectable titer developing over 5 to 16 weeks after the sensitizing event.
IgM antibodies do not cross the placenta.
Once antibodies are developed, the Mom is immunized for life.
Term
Isoimmunization: Rh Negative
Definition
Aslo known as D or Du negative.
Rh (D) negtive mother with D+ baby
In 40% of pregnancies fetal blood passess to maternal.
Mother first forms IgM antibodies, too big to pass to baby.
Then forms IgG can cross placenta, destroys D+ blood.
Antibody formation called maternal sensitization.
"Memore" increases antibody production with next pregnancy.
Term
Rh fetal risks
Definition
Severe anemia from hemolysis, large numbers of immature erythrocytes, erythroblastosis fetalis, hydrops fetalis (cardiac decompensation), hypoxia from anemia, death.
Term
Rh surveillance
Definition
Monder: Indirect coombs- anti-D antibodies are unbound, absorbed only to red cells of fetus, If + identify as IgG and quantify critical titer 1:16 or >
Fetus: direct coombs
Term
Treatment for Neaonate Rh
Definition
Blood type, Rh, Hgb, Direct Coombs
Transfuse for severe anemia and or hyperblirubinemia, itrauterine exchange transfusion o negative blood, crossmatch with mom, early delivery, phototherapy for mild jaundice
Term
Rh sensitization
Definition
Problem possibly- A potential problem exists when and Rh-negative mother and an Rh-positive father conceive a child who is Rh positive.
A mothe rmay become sensitized or produce antibodies to her fetus's Rh-positive blood.
Indirect coombs test doen on the mothers blood to measure the number of Rh-positive antibodies.
Direct coombs test done on the nfants blood to detect antibody coated Rh positive RBCs.
Term
When to give Rhogam in 72 hours
Definition
Indirect coombs test is negative and the infants direct coombs test is negative (sensitization has not occured)
Term
When not to give Rhogam
Definition
Indirect coombs test is positive and Th positive infant has a positive direct coombs test rhogam is not given, the infant should be monitored for hemolytic disease. It is recommended the Rhogam be given at 28 weeks.
Term
Management of Rh incompatibility Prenatal Prevention
Definition
Rhogam at 28 weeks for unsensitized women
Term
Managment of Rh incompatibility Postpartum
Definition
Check direct coombs test
Rhogam to mom if baby is Rh+ within 72 hours of birth
Term
Administration of Rh Immune Globulin
Definition
After birth of an Rh+ infant, After spontaneous or induced abortion, after ectopic pregnancy, after invasive procedures during pregnancy, after maternal trauma, must be within 72 hours.
Term
ABO incompatibility
Definition
Type O mothers with a Type A or B fetus
Group O infants because they have no antigenic sites o the RBCs are never affected regardless of the mothers blood type
Once women becomes pregnanct anti-A and anti-B antibodies cross the placenta and can produce hemolysis of fetal RBCs.
Term
Group B streptococcus Infection
Definition
Group B strep is a bacterial infection found in the lower GI or urogenital tract.
GBS may be transmitted to the fetus in utero during childbirth.
Responsible for maternal morbidity:
pyelonephritis, chorioamnionitis, PP endometritis, sepsis, meningitis
Term
GBS
Definition
may result in still births, transmission from mother when fetus passes through the birth canal.
Risk factors:
Prematurity, maternal intrapartum fever, membranes ruptured for longer than 18 hours, previously infected infant, GBS baceriuria in current pregnancy, young maternal age, african american or hispanic
Term
GBS manifestation in Newborn
Definition
Respiratory distress, pneumonia, apnea, shock, meningitis, neurologic damage
Term
Disorders of Amniotic Fluid
Definition
Polyhydraminos- S/S uterine distention, dyspnea, edema of lower extremities- Treatment therapeutic amniocentesis

Oligohydramnios- Risks- Cord compression, musculoskeletal deformities, pulmonary hypoplasia Treatment- amnioinfusion
Term
Polyhydramnios
Definition
amniotic fluid >2000 mls caused by abnormal or excessive fetal urination; frequently found in pregnancies with maternal diabetes, multiple gestation and isoimmunization. Can result in maternal respiratory compromise, fetal malpresentation and cord prelapse; managed by amniocentesis or amniotomy.
Term
Oligohydramnios
Definition
amniotic fluid <500mls in second or third trimester caused by any conditio the blocks production of urine or from getting it into amniotic sac. Can result in fetal cord compression, intolerance to labor, negative fetal outcomes. Found in pregnancies with fetal anomalies, maternal hypertension and post dates.
Term
Menopause
Definition
Menopause is defined as the absence of menstruation for 1 full year
Occurs around 50 to 51 years of age
Perimenopause-the time before menopause during which the woman moves from ovulatiory cycles to cessation of menses
Perimenopause may last from 2 to 8 years
Term
Physical aspects of menopause
Definition
Anovulation
Reduced fertility
Decreased or increased menstrual flow
Menstrual cycle irregularities
Amenorrhea
(
Term
Osteoporosis
Definition
Decrease in bone strength related to dimished bone desity and bone quality.
Estrogen regulates weight and fat metabolism during menopause.
Fat accumulation may occur in the trunk region.
Term
Osteoporosis risk factors
Definition
Presonal hx of fracture after age 50
Current low bone mass
female
weight less than 127
Family history
anorxia
low lifetime of calcium
vitamin D deficiency
Inactive lifestyle
Deficiency in estrogen
Term
Contraceptives
Definition
Family planning may be acceptable following the churches teaching
All family planning or contraceptive use needs to meet an individuals need
Term
Hormonal Contraceptives
Definition
Progestin only, syntheic form of progesterone, combination of estrogen and progestin, combination of estrogen and progestin is highly successful, inhibit the release of an ovum by creating and atrophic enometrium and by maintaining thick cervical mucus which slows/inhibits the transport of sperm.
Term
Hormonal contraceptives II
Definition
Combined oral contraceptives are on of the most popular options (combined estrogen and progestin)
Safe, highly effective, and rapidly reversible, taken 21 to 28 days, seasonale and seasonique extended use of estrogen and progestin are taken for 84 days and then followed by a blank pill for 7 days. May have bleeding four times a year.
Term
Extended use of Hormonal contraceptives may reduce the following side effects
Definition
Bloating, headache, breast tenderness, cramping, swelling
Term
Progesterone
Definition
A hormone proudced by the avaries that helps prepare the uterus for pregnancy. It is first produced by the corpus luteum in the ovaries and later is maintained by the placenta.
Term
What does progesterone do
Definition
Helps to regulate the menstrual cycle, prepares the lining of the uterus for implantation, keeps the lining of the uterus thick which is necessary for a successful pregnancy, produces a rise in temperature after ovulation which remains until mentruation occurs, creates a nutrient rich environment for the baby by increasing glycogen and arterial blood to the lining of the uterus, keeps the uterus from having contractions, causes the cervix to thicken and create a mucous plug which prevents bacteria from enterin the uterus.
Term
Family planning
Definition
Fertility awareness based methods documenting changes in the women's menstrual cycle. Life san of sperm 2-7 days, ovum 1-3 days, maximum fertility occurs approximately 5 days before ovulation and decreases rapidly the day after, couple abstains from intercourse.
Term
Basal body temperature Method
Definition
Detects fertility due to temperature change, take temperature every morning for 3-4 months of recording cycle, temperature changes may indicate women is fertile, temperature may riske after ovulation and remain elevated due to the increase in progesterone. Women abstains from intercourse day the temperature rises until 3 days later. If the temperature is a straight line, not ovulating.
Term
Situational contraceptives
Definition
abstinence, coitus interupptus, douching
Term
Contraception
Definition
When contraception is used there is lower incidence sexually transmitted diseases including HIV, fewer unwanted pregnancies
Term
Barrier Methods of Contraception
Definition
Male Condom, femal condom, diaphragm, cervical caps, vaginal sponge, intrauterine devices, male condome is the safest means to protect an individual from contracting HIV or other STI.
Term
Diaphragm
Definition
Steel band that forms a rings and is covered with latex or silicone so that when the diaphragm is inserted, the ring lodges high in the vagina with the latex or silicone covering of the cervix.
Term
How to use the diaphragm
Definition
Must be inserted before intercourse with one teaspoon of spermicidal jelly placed around its rim and in the cup. The diaphragm is inserted through the vaginal and covers the cervix. Push the diaphragm under the symphysis pubis, should not cause discomfort. If more than 6 hours lapse, should be reinserted. Should be left in for 6-8 hours after intercourse.
Term
IUD
Definition
Inserted in the uterus, copper may be left for 10 years, mirena left for 5. May be used to prevent the implantation of the ovum, mirena produces thick cervical mucus which inhibits the entry of sperm, releases levonorgestrel on a daily baiss.
Term
Complications of non hormonal IUD
Definition
Increased bleeding, increased cramping, increased of pilvic infection following insertion, abnormal bleeding, dysmenorrhea
Term
Hormonal contraceptive contraindications
Definition
Current pregnancy
Hx of thrombophlebitis
Hx of thromboembolic diesease
Acute or chronic liver disease
Estrogen dependent carcinomas
Undiagnosed uterine bleeding
Heavy smoking
Migraines
Diabetes
Amenorrhea
Term
Hormonal contraceptive indications
Definition
Diminished menstrual cramps
Diminished or decreased menstrual flow
Reduction in the incident of ovarian cancer, ovarian cancer, endometrial cancer, colorectal cancer
Reduction in migraines
May improve bone density
May decrease hot flashes
Term
When taking hormonal contraceptive
Women should contact physician immediately for the following:
Definition
Abdominal pain
Severe chest pain
Shortness of breath
Headache
Dizziness
Severe leg pain!!!!Combination Oral contraceptives may be altered due to Abx, over the counter medications, or herbal supplements
Term
Transdermal hormonal change
Definition
Contraceptive skin patch (Ortho EVera)
Combined hormonal contraception
Applied weekly for 3 weeks
Fourth week it is taken off
Patch is applied the first day of menses
Cannot use if weigh over 198 lbs
Term
Nuva Ring
Definition
Vaginal Contraceptive Ring
Low dose sustained release
Ring is left in place for 21 days and then removed for 7 days
Contraindicated with a previous vaginal prolapse
Term
Progestin contraceptives
Definition
Minipill (progestin only)
Used for breastfeeding Mom’s
Used by women who have a contraindication to the estrogen component such as thrombophlebitis or hypertension
Progestin may cause amenorrhea or irregular bleeding
Term
Adaptations to pregnancy reproductive system- UTERUS
Definition
Physiologic changes- increase levels of estrogen/progesterone, enlargement of the uterus, expanded circulatroy volume leading to increased vascular congestions, Acid pH o f vagina

Clinical signs/symptoms- hypertrophy of uterine wall, softening of vaginal muscle and connective tissue, increased uterine contractility (estrogen) leading to braxton hicks, hypertophy of cervical glands leading to mucous plug, increased vaginal glands leading to increased leukorrhea, cessagtion of menstruation/ ovulation. Increat to 20x that of nonpregnant uterus, weight increases from 70-1000g.
Blood flow to the uterus is 500-600mL at term, goodell's sign-cervical tip softens around 6 weeks. Hegar's sign- softening of the lower uterine segment, chadwick's sign-bluish coloration of cervix, mucosa and vulva.

Inhibits grwoth of bacteria, increased growth of candida albicans, leading to increased risk of candidasis.
Term
Adaptations to pregnancy reproductive system- Breasts
Definition
Physiologic changes- increase of estrogen and progesteron levels,initially produced by corpus luteum then by the placenta.
Increase of prolactin produced in the anterior pituitary.
Clincial S/S
Tenderness, fullness, tingling sensation, increase in weight by 400g, enlargement of breasts, nipples, areola, nipples become more erect, areolae become darker, glandular hyperplasia, and hypertrophy of montgomery tubercles, stria, prominent veins d/t a twofold increase in blood flow, increased growth of mammary glands, increase in lactiferous ducts and alveolar system, production of colorstrum by end of 16th week.
Term
Adaptations to pregnancy- cardiovascular
Definition
Physioloic changes- decrease in peripheral vascular systm, increase in blood volume by 40-50%, Increase in cardiac output by 30-50%, Increase in RBC count by 30%, increase in RBC volume by 17-30%, Increase in WBC cound, increased demand for iron in fetal development, hypercoagulability, growing uterus displaces the heart upward and to the left, decrease in systemic and pulmonary vascular resistance, increased venous pressure and decreased blood flow to extremities 2/2 compression of iliac veins and inferior vena cava.

Clinical s/s- decreased BP, hypervolemia of pregnancy, increased HR 15-20BPM, exchange of nutrients, oxygen and waste products within the placenta, needs of expanded maternal tissue, reserve blood loss at birth, increased stroke volume of 30%, systolic murmurs, increase in heart size.
Physiological anemia of pregnancy, hemodiultion caused by increased plasma volume being relatively larger than the increase in RBC leading to decreased hemoglobin and decreased hematocrit.
Up to 15,000 WBC in the absence of infxn, iron-deficiency anemia: HgB <11g/dL and Hct <33%
Plasma fibrin increase of 40%
Fibrinogen increase of 50%
Decrease in coagulation inhibiting factors
Protective of inevitable blood loss during birth
May see a change in location of heart when auscultating heart sounds
BP does not increase due to the decreased resistance in the bessels
Edema of the lower extremities, varicosities in legs and vulva, hemorrhoids.
Term
Adaptations to Pregnancy- Respiratory
Definition
Physiological changes- Hormones stimulate the respiratory center and act on lung tissue to increase and enhance respiratory function.
Increase of oxygen consumtpion by 20%
Estrogen, progesterone, and prostaglandin cause vascular engorgement and smooth muscle relaxation, upward displacement of diaphragm by englarging uterus
Estrogen causes a relaxation of the ligaments and joints of the ribs

Clinical S/S- Increase in tidal volume by 30-40%, Slight increase in respiratory rate, increase in inspiratory capacity, decrease in expiratoryvolume, slight hyperventilation, slight respiratory alkalosis, dyspnea,
Nasal and sinus congestion, epistaxis,
shift from abdominal to thoracic breathing, chest and thorax expand to accomodate thoracic breathing and upward displacement of the diaphragm.
Slight decrease in lung capacity.
Term
Adaptations to Pregnancy- Renal
Definition
Physiologic changes- Increased progesterone levels leading to relaxations of smooth muscle, pressure of enlargin uterus on renal structures, alterations in CV system lead to increased renal blood flow of 50-80% in 1st trimester then decreases
Decreased renal flow in third trimester
Increased vascularity
Excretion of waste for mom and fetus

Clinical S/S- Dilation of renal pelvis and ureters leading to increased risk of UTI
Ureters become elongated with decreased motility leading to increased risk of UTI.
Decreased bladder tone with increased bladder capacity leading to frequency and incontinence and increased risk of UTI.
Displacement of bladder in 3rd trimester leads to urinary frequency and nocturia.
Increased GFR leads to inreased urinary output.
Increased GFR leads to increased renal excretion of glucose and protein leading to glucosuria and proteinuria.
Dependent edema
Hyperemia of bladder and urethra, increased frequency
Term
Adaptations to pregnancy- Gastrointestinal
Definition
Physiological changes-
Increased levels of hCG and altered carbohydrate metabolism, increased progesterone levels lead to decreased muscle tone and slowing of digestive process
Increased progesterone leads to decreased muscle tone of gallbladder leads to prolonged emptying time
Changes in senses of taste or smell
Displacement of intestines by uterus
Increased levels of estrogen lead to increased vascular congestion of mucosa

Clinical S/S-
Nausea and vomiting in early pregnancy, constipation, straining may lead to hemorrhoids, delayed gastric emptying lead to heartburn (pyrosis)
Increased risk of gallston fotmation and cholestasis, increase or decrease in appetite, retention of bile salts which can lead to itching, nausea, Pica, flatulence, abdominal distention, abdomincal cramping, and pelvic heaviness. Gingitis, bleeding gums, increased risk of periodontal disease.
Term
Adaptations to pregnancy- musculoskeletal
Definition
Physiological changes-
Increased progesteron and relxin levels lead to softening of joints and increased joint mobility leading to widening and increased mobility of scroiliac and symphysis pubis

Distention of abdomen 2/2 to uterus, reduced abdominal tone, increased breast size, increased estrogen and relxin levels lead to increased elasticity and relaxation of ligaments, abdominal muscles stretch due to enlarging uterus, Human Placental Lactogen (HPL) produced by placenta increases insulin resistance by altering glucose metabolism.

Clinical S/S-
Atered gait- waddling, facilitates birthing process, Pelvis tilts forward leading to shifting of center of gravity leading to change in posture and walking style increasing lordosis. Round ligament spasm, increased risk of joint pain and injury, diastasis recti, gestational diabetes.
Term
Adaptations to pregnancy- Integumentary
Definition
Physiological changes- Estrogen and progesterone levels stimulate increased melanin deposition leading to light brown to dark brown pigmentation, Increased blood flow increased BMR, progesterone induced increase in body temperature, and vasomotor instability, increased action of adrenocorticosteroids lead to cutaneous elastic tissues becoming fragile, increased estrogen levels lead to color and vascular changes, increasedandrogens lead to increased in sebaceous glands

Clinical S/S- linea nigra, melasma, darkening of nipples, areola, vulva, scars and moles. Hot flashes, facial flushing, alternating sensations of hot and cold, increased perspiration, stria gravidarum on abdomen, thighs, breasts and buttock, angiomas, plamar erythema, pinking mottling over palms of handes increased oiliness of skin and increase of acne.
Term
Adaptations of pregnancy- Hormones
Decreased follicle stimulating hormone
Definition
Amenorrhea
Term
Increase Progesterone
Definition
Maintains pregnancy by relaxation of smooth muscle
Term
Increased estrogen
Definition
Decreased GI motility
Facilitates uterine and breast development
Facilitates increases in vascularity
Hyperpigmentation
Alters metabolic processes and fluid and electrolyte balance
Term
Increased prolactin
Definition
Facilitates lactation
Term
Increased Oxytocin
Definition
Stimulates uterine contractions
Stimulates the milk let-down reflex in response to breastfeeding
Term
Human Placental lactogen
Definition
Facilitates breast development
Alters carb, protein, and fat metabolism
Faciliatates fetal growth by altering maternal metabolism; acts as an insulin atagonist
Term
Hyperplasia and increased vascularity of thyroid
Definition
Enlargement of thyroid
Heat intolerance and fatigue
Term
Increased human chorionic gonadotropin (hCG)
Definition
Maintenance of corpus luteum until placenta is full functional
Term
Increased BMR related to fetal meatbolic activity
Definition
Depletion of maternal glucose stores leads to increased risk of maternal hypoglycemia, increased production of insulin, increase in maternal resistance to insulin leads to increased risk of hyperglycemia
Term
Which medications are used to induce labor?
Definition
Pitocin/Oxytocin

Cytotec/Misoprostil

Dinoprostone/Prepidil
Term
Used as a tocolytic medicine to slow uterine contractions during preterm labor.

Also used to stop or prevent convulsions of eclampsia.
Definition
Magnesium Sulfate
Term
Antidote for Magnesium Sulfate
Definition
calcium gluconate
Term
Beta agonist used to stop contractions
Definition
Terbutaline
Term
Used to stimulate fetal lung maturation
Definition
Betamethasone
Term
What is the route/routes that Misoprostil (Cytotec) can be given?
Definition
Vaginally (may be 25-200 mcg)

Rectally (800mcg-1000mcg)

Orally
Term
Can Tylenol and Motrin be given at the same time Postpartum?
Definition
YES
Term
What is procardia used for
Definition
Use of nifedipine or procardia for the treatment of preterm labor is an unlabeled use of the drug. Nifedipine, a calcium channel blocker, is more commonly used to treat high blood pressure and heart disease.
Term
Which PPH medication is contraindicated with high blood pressure?
Definition
Methergine
Term
When should Simethicone be given?
Definition
Typically for a c-section patient. After each meal and at bedtime.
Term
Should the infant be left alone in the room when a Mom is given Ambien?
Definition
NO!
Term
What is Lanolin used for and when should it be applied?
Definition
After breastfeedings and do not wipe off in between feedings!
Term
Which products are comfort products for the perineum?
Definition
Tucks
Epifoam
Americaine Spray
Ice pack
Sitz bath
Term
Which medications are used to treat/prevent nausea vomiting?
Definition
Phenergan
Zofran
Reglan
Vistaril
Scopolamine patch
Term
If a patient becomes hypotensive after the placement of an epidural, which medications might be used?
Definition
IV Bolus

Hespan (hetastarch) (volume expander)

Ephedrine (stimulant)
Term
Which medications could be used for a Gravid hypertensive patient?
Definition
Hydralazine

Labetalol HCL

Nifedipine

Methyldopa (wishing to breastfeed)
Term
What medications might be used to treat a PPH?
Definition
Oxytocin

Cytotec (prostaglandin)

Methergine (ergot alkaloids)

Hemabate (prostaglandin)
Term
Can Percocet and Tylenol be given together?
Definition
NO
Term
How soon should Rhogam be given after delivery is the Mom is sensitized?
Definition
72 hours
Term
TORCH Infections
Definition
Infections acquired in utero or during the birth process are a significant cause of fetal and neonatal mortality and an important contributor to early and later childhood morbidity
Term
Five infections of TORCH
Definition
Toxoplasmosis
Other Infections (syphilis)
Rubella
Cytomegalovirus (CMV)
Herpes simplex virus (HSV)
Term
Toxoplasmosis
Definition
Toxoplasmosis is an infection due to the parasite Toxoplasma gondii
Caused by animals (cats, birds), undercooked meat, contaminated soil
Toxoplasmosis in the uterus often have no symptoms at birth, but will later develop serious complications such as mental retardation and blindness. Some may have eye or brain damage at birth.
Bactrim of the abx of choice for treatment
The risks to the baby are the greatest if infection occurs during the first trimester. Infection with toxoplasmosis can also cause miscarriage, intrauterine growth retardation and preterm labor
Detected through a blood test
Term
Syphilis
Definition
Chronic infection caused by the spirochete
Acquired through vaginal, oral, anal intercourse
Transplacental congenital transmission may occur
Incubation period of 10-90 days
Detected through a blood test
Primary stage-chancre (painless ulcer), mild fever, loss of weight
Secondary-skin eruptions called condylomata lata which resemble wart like…may present on the vulva, arthritis, enlargement of the liver and spleen
May be transferred via the placenta, may cause stillbirth, IUGR, preterm birth
Treated with PCN-G
Term
Rubella
Definition
Can have teratogenic effects on the fetus during the first trimester
May cause congenital cataracts, deafness, heart defects, or mental retardation
Infants should be isolated (IgM antibody is found)
Term
Cytomeglovirus
Definition
Cytomegalovirus is related to the viruses that cause chickenpox and herpes simplex
Once you're infected with CMV, the virus remains with you for life, but it's not always active. CMV may cycle through periods during which it lies dormant and then reactivates. If you're healthy, it mainly stays dormant (content provided by the MayoClinic, 2011)
Most babies who are infected before they're born appear healthy at birth, but a few develop signs over time —sometimes not for months or years after birth. The most common of these late-occurring signs is hearing loss. A small number may develop vision impairment as well
Babies with congenital CMV who are affected at birth tend to be very sick. Signs and symptoms include:
Yellow skin and eyes (jaundice)
Purple skin splotches or a rash or both
Small size at birth (or low birth weight)
Enlarged spleen
Enlarged and poorly functioning liver
Pneumonia
Seizures
4/7/201215
Touching your eyes or the inside of your nose or mouthafter coming into contact with the body fluids of an infected person. This is the most common way CMV is spread because it's absorbed through the mucous membranes.
Through sexual contactwith an infected person.
Through the breast milkof an infected mother.
Through organ transplantationor blood transfusions.
Through the placenta,from an infected mother to her unborn child,or during birth.
Treatment is an antiviral…no cure!
No evidenced base therapy exists
Term
HSV
Definition
1 and 6 people between the ages of 14-49 are infected with herpes simplex
HSV-I and HSV-II-can cause painful lesions in the genital area or the cervix
Presence of lesions may effect the fetus
Spontaneous abortion (if in first trimester)
Pre-term labor
IUGR
Sx’s up to 4 weeks after birth include fever, jaundice, seizures, poor feeding
MOC should be treated with acyclovir at 36 weeks or have a C/S
Term
Human Papiloma
Definition
HPV-genital warts is caused by the HPV virus
May be gray like cauliflower lesions
May contribute to cervical dysplasia
Should have frequent pap smears to monitor cervical dysplasia
Term
Hepatitis
Definition
Inflammatory process of the liver caused by an infection of A,B, C, D, E
A, B, C are caused by blood born pathogens
If MOC is Hepatitis B positive HBIG may be given up to 12 hours
It is encouraged that ALL newborns get the Hepatitis B immunization
Term
Amniotic fluid infections
Definition
PROM
Positive Nitrizine Test
Copious fluid leaking into the introitus
Monitor time, color, and smell
Continue to monitor temperature every 4 hours
If ruptured over 24 hours…patient is at risk of infection
Term
Breast exams
Definition
Mammogram is a soft tissue x-ray image of the breast taken without the injection using contrast
It can detect lesions in the breast before they are palpated
Recommended for all women over the age of 40 to do self exams
Self breast exams should be done each month (see page 119-120)
Don’t forget to remind your loved ones (including yourself) to perform this test each month!!!!
Term
Chromosomes
Definition
Chromosomes-composed of deoxyribonucleic acid (DNA) and protein
Chromosome resembles an X (centromere, short arm, and long arm)
Term
Genes
Definition
Regions in DNA strands that contain coded information used to determine the unique characteristics or traits of an individual
Genes in the autosomes determine hair color or blood type
Genes in the sex chromosomes determine gender
Term
Cell Division
Definition
Each human begins life as a single cell called fertilized ovum or zygote
Cells are reproduced by mitosis or meiosis
Term
Mitosis
Definition
Process of cell division that results in daughter cells that are exact copies of the original cell
Term
Meiosis
Definition
Meiosis is the type of cell division which give rise to gametes
When fertilization occurs the normal diploid number is restored
Term
Gamatogenesis
Definition
Meiosis occurs during gametogenesis
Oogenesis is the process that produces the female gamete called the ovum (egg) and the male gamete called the sperm
The ovum and the sperm unite to form the zygote
Term
Oogenesis
Definition
Is the process that produces the female gamete called an ovum (egg)
Ovary gives rise to oogonial cells which develop into oocytes
Meiosis begins and stops before birth.
Cell division resumes at puberty.
Development of Graafian follicle
Term
Spermatogenesis
Definition
Production of sperm
First meiotic division:
Primary spermatocyte replicates and divides.
Second meiotic division:
Secondary spermatocytes replicate and divide.
Produce four spermatids
Term
Fertilization
Definition
When the sperm and Ovum unite.
New cell has 23 chromosomes from the ova and 23 from the sperm returning to diploid number of chromosomes.
Formation of gametes
gametogenesis
Term
After sperm entry
Definition
Zone pellucida blocks additional sperm from entering
Secondary oocyte completes second meiotic division
Forms nucleus of ovum
Nuclei of ovum and sperm unite
Membranes disappear
Chromosomes pair up
Term
Tubal transport of the zygote
Definition
Zygote is formed by the union of the sperm and ovum.
Transported to the Uterus by the fallopian tubes
During transport the zygote undergoes rapid mitotic division or cleavage
Term
Morula
Definition
Enters the uterus on day 3 and floats around for another 2-4 days.
Cells form a cavity and two distinct layers evolve.
Inner layer
Blastocyst
Outer layer
Trophoblast
Term
Blastocyst
Definition
Develops into the embryo and embryonic membranes
Term
Trophoblast
Definition
Develops into an embryonic membrane called the Chorion
Chorionic villi
Amnion
Yolk sac
Term
Implantation
Definition
7-10 days after conception
Trophoblast burrows into the endometrium until the blastocyst is covered
Endometrium is now called decidua
Chorionic Villa develop from the trophoblast and extend into endometrium
These villi obtain oxygen and nutrients and dispose of carbon dioxide
Term
Cell Differentiation
Definition
Chorion
Developed by the trophoblast and envelops the amnion, embryo and yolk sac
Has villi projections that extend into the uterine wall and form the embryonic/fetal portion of the placenta

Amnion
Second thin membrane
Envelops the embryo and protects it
The Chorion and Amnion together form the amniotic sac filled with fluid.
Term
Amniotic sac
Definition
Protection
Maintains an even temperature
Prevents the amniotic sac from adhering to the fetal skin.
Allows symmetrical growth
Provides a positive pressure environment for fetal lung development
Term
Yolk Sac
Definition
9thday the yolk sac develops
Functions only during embryonic life
Initiates the production of red blood cells until about 6 weeks when the liver takes over
The umbilical cord than encompasses the yolk sac and it degenerates
Term
Germ Layer
Definition
After implantation the embryonic disks transforms into three primary germ layers
Ectoderm
Mesoderm
Endoderm
Term
Ectoderm
Definition
Outer layer of skin
Hair follicles
Nails and hair
External sense organs
Mucous membranes
Term
Mesoderm
Definition
True skin
Skeleton
Bone and Cartilage
Connective Tissue
Muscles
Blood and blood vessels
Kidneys and gonads
Term
Endoderm
Definition
Lining of trachea, pharynx, and bronchi
Lining of digestive tract
Lining of bladder and urethra
Term
Placenta
Definition
Metabolic and nutrient exchange
Maternal portion:
Decidua
Fetal portion:
Chorionic villi
Fetal surface covered by amnion
Term
Placental Development
Definition
Chorionic villi form spaces in decidua basalis
Spaces fill with maternal blood.
Chorionic villi differentiate:
Syncytium: outer layer
Cytotrophoblast: inner layer
Anchoring villi form septa
Term
Placental Functions
Definition
Nutrition
Excretion
Fetal respiration
Production of fetal nutrients
Production of hormones
Term
Placental Hormones
Definition
Organ for fetal respiration, nutrition, and excretion
Only temporary organ
Produces four hormones
Progesterone -decreases myometrial activity
Estrogen-increases myometrial activity
Human chorionic gonadotropin (hCG)-maintains corpus luteum
Human placental lactogen (hPL)-promotes fetal growth; regulates glucose availability for the fetus as an insulin antagonist
Term
Umbilical cord
Definition
Body stalk fuses with embryonic portion of the placenta
Provides circulatory pathway from chorionic villi to embryo. Delivers oxygenated blood:
One vein
Delivers deoxygenated blood from fetus:
Two arteries
Develops with the placenta and fetal blood vessels
Two arteries carry blood away from fetus
One vein carries blood to fetus
Normal length is 55 cm
Wharton’s Jelly protects cord
Cord is coiled for protection
Term
Fetal circulation
Definition
After the fourth week of gestation, circulation to the fetus is well established.
Fetus does not breathe oxygen
Liver does not process waste products (placenta does)
Fetus has three shunts to promote circulation
Term
Fetal Shunts
Definition
Foramen ovale
Opening into the left atrium
Mixes with small amount of deozygenated blood returning from the fetal lungs through the pulmonary veins
Ductus venosus
Mixes w/ deoxygentated blood from legs and abdomen on way to right atrium
Ductus arteriosus
Bypasses lungs
Term
Three stages of prenatal development
Definition
Zygote: cell formed by union of sperm and ovum
Embryo: 2nd to 8th week of development
Fetus: 9th week until birth
Term
Fetal development week 6
Definition
Trachea is developed
Liver produces blood cells
Trunk is straighter
Digits develop
Tail begins to recede
Term
Fetal development week 12
Definition
Eyelids are closed
Tooth buds appear
Fetal heart tones can be heard
Genitals are well-differentiated
Urine is produced
Spontaneous movement occurs
Term
Fetal development week 16
Definition
Lanugo begins to develop
Blood vessels are clearly developed
Active movements are present
Fetus makes sucking motions
Swallows amniotic fluid
Produces meconium
Term
Fetal development week 20
Definition
Subcutaneous brown fat appears
Quickening is felt by mother
Nipples appear over mammary glands
Fetal heartbeat is heard by fetoscope
Term
Fetal development week 24
Definition
Eyes are structurally complete
Vernix caseosa covers skin
Alveoli are beginning to form
Term
Fetal development week 28
Definition
Testes begin to descend
Lungs are structurally mature
Term
Fetal development week 32
Definition
Rhythmic breathing movements
Ability to partially control temperature
Bones are fully developed but soft and flexible
Term
Fetal development week 36
Definition
Increase in subcutaneous fat
Lanugo begins to disappear
Term
Fetal development week 38
Definition
Skin appears polished
Lanugo has disappeared except in upper arms and shoulders
Hair is now coarse and approximately 1 inch in length
Fetus is flexed
Term
Factors influencing development
Definition
Quality of sperm or ovum
Genetic code
Adequacy of intrauterine environment
Teratogens
Term
Weight gain
Definition
25-35 lbs for normal weight
15 -20 lbs for overweight
Up to 40lbs for underweight
Term
Diagnosis of pregnancy
Definition
Combination of presumptive, probable, and positive changes/signs of pregnancy. This information is obtained through history, physical, pelvic examination, laboratory, and diagnostic studies.
Term
Signs of pregnancy
Definition
Presumptive/Subjective
Amenorrhea
Nausea and vomiting
Urinary frequency
Quickening
Objective (probable signs:
Hegars sign
McDonald’s sign
Braxton Hicks
Skin hyperpigmentation
Uterine souffle
Striae/pigmentation
Linea Nigrea
Term
Positive changes of pregnancy
Definition
Fetal heartbeat
Fetal movement
Visualization of the fetus
Term
Uterus
Definition
Pre-pregnancy: pear shaped and small (60g)2 ounces
End of pregnancy: greater than 5 times larger (60g)2.5 lbs
Initial changes are stimulated by increased estrogen and progesterone levelsThe circulatory requirement increases as the fetus grows and the placenta develops
Blood increases
Lymphatic vessels within the uterine layers increase
1/6 of maternal blood volume is contained within the vasculature of the uterus

Shape
›Upside down pear at conception
›Becomes more elastic and global
›Grows out of a pelvic cavity organ into the abdominal cavity
Non pregnant size of a plum
7 weeks size of an egg
10 weeks size of an orange
After the 4thmonth contractions can be felt
Placenta perfusion depends on the maternal blood flow to the uterus, blood flow increases as the uterus enlarges
Braxton Hicks
Placenta
Placenta takes up ½ of the uterus (20 weeks)
Placenta-after 20 weeks becomes thicker (not wider)
Term
Cervix
Definition
Nullipara
›Round
Multipara
›Enlongated
Mucous plug
Goodell’s sign
Chadwick’s sign
Term
Ovaries
Definition
Ovaries cease ovum production during pregnancy.
Early pregnancy the human chorionic gonadotropin (hCG) maintains the corpus luteum
Corpus luteum secretes progesterone until the placenta produces enough progesterone to maintain the pregnancy
Term
Vagina and Vulva
Definition
Pregnancy prepares the vagina to stretch
›Walls thicken
›Connective tissue loosens
›Smooth muscle hypertrophies (due to estrogen)
›Vaginal vault elongates
Changes in vagina are estrogen induced
Increase in vaginal secretions to prevent infections
By the end of pregnancy, the vaginal wall and perineal body have become sufficiently relaxed to permit distention and passage of the infant
Term
Breasts
Definition
Estrogen and progesterone induce changes in the mammary glands
Striae
Colosturm
Term
Respiratory
Definition
Pregnancy may produce hyperventilation
Tidal volume may increase (30% to 40% rise)
Oxygen consumption
Vital capacity and inspiratory reserve volume are unchanged
Expiratory reserve volume falls by 20%
The volume of lung is decreased
Diaphragm is elevated and subcostal angle is decreased
Risk for lung disease may increase due to the increased need for oxygen
Rhinitis of pregnancy
Epistaxis
Term
Cardiovascular
Definition
Heart may be pushed upward and to the left
Systolic murmur may be auscultated
Blood volume increases up to 34 weeks
Vena Cava Sydrome
Cardiac output increases
Organs systems receive additional blood flow
Pulse rate may increase during pregnancy
Blood pressure may decrease during
2ndtrimester but increase 3rdtrimester
Pulse may increase
Femoral venous pressure slowly rises
Orthostatic hypotension
›Cardiac output suddenly decreases d/t venous return from the lower body falls
Palpatations
›Increases in thoracic pressure w/ sudden movement
Pseudoanemia
›Fluid part of blood increases more than the erythrocyte component gives a false dilutional anemia
Term
Supine Hypotention/ Vena Cava syndrome
Definition
Weight of the uterus compresses the vena cava, reducing the amount of blood returned to her heart
›Faintness
›Lightheadedness
›Agitation
›Dizziness
Term
GI system
Definition
Nausea and vomiting (first trimester)
Ptyalism
Bleeding gums
Gastric tone and mobility decrease
Pyrosis
Uterus enlarges displacing the stomach and intestines toward the back slowing mobility
Pruritus
Gallstones
Liver function
Term
Mothers response to pregnancy
Definition
Ambivalence
Acceptance
Introversion
Mood swings
Changes in body image
Term
First trimester
Definition
Difficult believing pregnancy
›Unwanted pregnancy
›Unplanned pregnancy
›Difficulty getting pregnant
Conflicting feelings
›Ambivalence
Emotional swings
Term
Second trimester
Definition
Fetus becomes more real
Stable time for the pregnancy
“Tries on” the role of motherhood
Body changes are more evident
Term
Third trimester
Definition
Body changes are more dramatic
Begins to separate herself from the pregnancy, commits to take care of the baby
Minor discomforts become more tiresome
Term
Father
Definition
Fathers go through similar phases
Ambivalence is typical
Development stages
›Announcement
›Adjustment
›Focus
Term
Father's response to pregnancy
Definition
Confused by partner’s mood changes
Feels left out of pregnancy
Resents attention given to the woman
Resents changes in their relationship
Needs to resolve conflicts about fathering
Couvade
Siblings:
›Rivalry
›Fear of changing parent relationships
Grandparents:
›Closer relationship with expectant couple
›Increasing support of couple
Term
Cultural factors
Definition
Identify beliefs, values, and behaviors:
›Ethnic background
›Patterns of decision making
›Religious preferences, language, communication style
›Common etiquette practices
›Expectations of healthcare system
Term
Goals of prenatal care
Definition
Ensure a safe birth for mother and baby by promoting good health habits and reducing risk factors
Teach health habits that may be continued after pregnancy
Educate in self-care for pregnancy
Provide physical care
Prepare patients for the responsibilities of parenthood
Term
Prenatal history
Definition
Assessment of current and past pregnancies
Gynecologic history
Current and past medical history
Family medical history
Religious, cultural, and occupational history
Partner history
Term
Prenatal visits
Definition
Ideally healthcare begins before conception.
Genetic counseling if necessary
Nutritional status
Folic acid
Immunizations
Prenatal visits should begin as soon as a woman suspects she is pregnant
Term
Inital prenatal visit
Definition
History and Physical Assessment
Lab/Diagnostic Studies
Comprehensive health and risk assessment
Current pregnancy history
Complete physical and pelvic exam
Determine EDD
Nutrition assessment including 24 hr diet recall
Psychosocial assessment
Assessment for Intimate Partner Violence
See page 345-351 in your book
•Blood Type and Rh Factor
•Antibody Screen
•CBC
•HIV Screen
•Hepatitis B surface antigen
•RPR, VDRL (syphilis serology)
•Genetic screening based on family history, racial/ethnic background
•Rubella Titer
•PPD
•Urinalysis
•Urine culture and sensitivity
•Pap Smear
•Gonorrhea and Chlamydia cultures
•Ultrasound-depending on gestation
Term
Psychosocial Assessment
Definition
History of emotional or physical abuse
History of emotional problems:
Depression and anxiety in general
Postpartum depression
Support systems
Overuse or underuse of healthcare system
Acceptance of pregnancy, intended or unintended
Personal preferences about the birth
Plans for care of child following birth
Feeding preference for the baby
Term
Factors related to fathers health
Definition
Family history of genetic conditions
Age
Significant health problems
Previous or present alcohol intake
Drug and tobacco use
Blood type and Rh factor
Occupation
Educational level
Methods by which he learns best
Attitude toward the pregnancy
Term
Danger signs of pregnancy
Definition
Gush of fluid from vagina
Vaginal bleeding
Abdominal pain
Fever and chills
Dizziness, blurred vision, spots before eyes
Persistent vomiting
Pretibial Edema
Muscular irritability or convulsions
Epigastric pain (RUQ pain)
Headaches unrelieved by Tylenol
Oliguria
Dysuria
Decrease or absence of fetal movement
Term
Types of Testing
Definition
Ultrasound
Doppler ultrasound flow assessment
Alpha-fetoprotein screening
Chorionic Villus sampling
Amniocentesis
Percutaneous Umbilical blood sampling
Non stress test
Contraction stress test
Biophysical profile
Fetal movement assessment
Triple Screen-Quad Test
Term
Assessment of Fetal Well Being
Definition
Ultrasound
Sonograms
Three dimensional ultrasound
Limited ultrasound
Standard ultrasound
Transabominal ultrasound
Transvaginal ultrasound
Term
Cervical Funneling
Definition
a cone shaped indentation in the cervical osindicating cervical incompetence or risk of preterm labor
Term
3Routine Ultrasound
Definition
Estimation of gestational age
Evaluation of cervical insufficiency
Evaluation of fetal growth
Evaluation of vaginal bleeding
Fetal presentation
Suspected multiple gestation
Hydatidiform mole
Fetal death
Placenta previa
Chromosomal anomalies
Fetal anomolies
Uterine size and clinical dates
Premature rupture of membranes
Ectopic pregnancy
Term
Doppler Ultrasound Blood Flow Assessment
Definition
Description-ultrasound measures rate and volume of blood flow and pressure through placenta and umbilical cord vessels
Purpose-to determine abnormality in the fetal cardiovascular system
Procedure-”Doptone” fetal pulse detector to assess blood flow and flow velocity waveforms available for analysis
Advantages-non invasive
Disadvantages-none
Term
Viability
Definition
Urine test does not determine viability
Bleeding (1 in 4 woman will have bleeding during pregnancy)
Bleeding may indicate an unviable pregnancy
Term
NuchalTranslucency Testing
Definition
A combination of an ultra sound and a maternal serum test that is used to screen fetuses between 11 weeks and 1 day and 13 weeks and 6 days to determine if a fetus is at risk for a chromosomal disorder such as Down syndrome (trisomy 21), trisomy 13, and trisomy 18
Risks-no maternal or fetal risks
Term
Chorionic VilliSampling
Definition
Performed between 8 to 10 weeks gestation
Involves aspirating the chorionic villi from the placenta for prenatal diagnosis of genetic disorders
Procedure-placental tissue sample obtained transabdominally or transcervically and grown out for karyotype
Advantages-quicker results (7-10 days after procedure); can be performed earlier than amniocentesis
Disadvantages and risks-7% fetal loss rate due to bleeding, infection, and ROM; fetal limb abnormalities; tests for metabolic disorders such as Cystic Fibrosis but does not test for NTD’s
Term
Multiple Marker Screening
Definition
Triple marker screening combines 3 chemical markers: AFP, hCG, and estriollevels with maternal age to detect some trisomiesand NTD’s
Quad screen adds inhibinA to increase detection of Trisomy 21 to 80%
Description-screening for fetal protein components; multiple pregnancy
Purpose-detect open neural tube defects-spinabifida, anencephaly: Down Syndrome, Rh disease,
Procedure-sample of maternal blood
Advantages-can detect possibility of open neural tube defects, one marker for Down Syndrome, Trisomy 18 etc.
Limitations-gestational age must be exact; can be falsely elevated for variety of reasons; screening test to be used with other tests such as US
Interpretation-
↓MSAFP and ↓unconjugatedestriollevel suggests abnormality
hCGand inhibin-A levels are twice as high in Trisomy 21
↓estriollevels indicate NTD’s
Term
Fetal Surveillance
Definition
Maternal
Prenatal conditions
Hypertensive disorder
Type 1 diabetes mellitus
Chronic renal disease
Preeclampsia
Decreased fetal movement
IUGR
Previous fetal demise
Known fetal anomaly
Term
AntepartumFetal Surveillance
Definition
Goals-identify risk factors for fetus in third trimester
Methods-fetal movement assessment; non stress test; contraction stress test; biophysical profile
Term
Biophysical Profile
Definition
Description-assessment of FHR accelerations, fetal breathing, fetal movements, fetal tone, amniotic fluid volume
Purpose-useful evaluation of decreased fetal movement, suspected IUGR, preterm labor, gestational diabetes, post term pregnancy, premature rupture of membranes
Procedure-ultrasound NST and amniotic fluid index
Interpretation-normal score for each indices is 2; abnormal score is 0; score 8/10 or 10/10 indicates healthy nonasphyxiated fetus if fluid is adequate; 6/10 indicates possible fetal asphyxia
Advantages-non invasive
Disadvantages-labor intensive and expensive, requires trained examiner with excellent interpretive skills
Term
Non-stress Test
Definition
Description-electronic fetal monitor tracing to observe acceleration of the FHR in relation to fetal movement
Procedure-FHR monitored electronically with accompanied tocodynamometer assessment of fetal movement; monitored for 20 minutes or longer
Interpretation-
Reactive if 2 or more accelerations 15bpmx15seconds in 20 minutes
Non reactive –lacks insufficient FHR accelerations over 40 minute period
Advantages-non invasive; can be repeated serially; reliable indicator of fetal well-being
Term
Maternal Assessment of Fetal Movement
Definition
Description-assessment of indirect fetal central nervous system integrity and function
Procedure-pregnant woman counts daily fetal movements for specified period of time ( 30 in one hour is norm)
Advantages-non invasive, cost effective
Disadvantages-requires good education for mother; increased anxiety; substances such as caffeine, tobacco smoke, drugs, alcohol interfere with fetal movements
Term
Contraction Stress Test
Definition
Purpose-evaluate the respiratory function of the placenta and identify fetus at risk for intrauterine asphyxia by observing the response of the FHR to the stress of uterine contractions
Procedure-stimulation by oxytocin of at least 3 uterine contractions of 40 seconds duration in 10 minutes. FHR monitor is attached as well as uterine contraction monitor (toco). Baseline assessment performed before addition of IV oxytocin or nipple stimulation
Interpretation-absence of late or significant variable decelerations is considered reassuring sign and test is NEGATIVE
the presence of late decelerations following 50% or more uterine contractions, even if fewer than 3 in 10 minutes is a sign of utero/placental insufficiency and is termed POSITIVE and indicates fetus is not obtaining sufficient oxygen
Equivocal or suspicious test –intermittent late decelerations or significant variable decelerations merit follow up testing
Equivocal-hyperstimulatory-decelerations occurring in the presence of UC that occur more frequently than 2 minutes or lasting longer than 90 seconds. Repeat test
Testing done in hospital setting; if POSITIVE CST and nonreactive NST, fetus should be sectioned if greater than 32 weeks
Term
Amniocentesis
Definition
Pregnant women who are 35 years old or greater
Couples who have had a child with a birth defect
Pregnant women with other abnormal test results
Description-fluid component analysis for fetal cells, fetal lung maturity
Purpose-chromosome analysis and AFP follow up; assessment of fetal lung surfactant components (lecithin and spingomyelin)
Procedure-sample of amniotic fluid withdrawn through needle inserted to uterus through the abdominal wall. US done prior to locate fetus and placenta
Advantages-can grow out fetal cells for analysis; can determine fetal lung maturity
Disadvantages-need enough fluid to obtain sample size; done after 14 weeks; 14-20 weeks for fetal diagnosis
Risks-loss of pregnancy 0.5%; Rh sensitization; infection
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