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OB Exam 1
I love You O LORD my strength! Psalm 18:1
399
Nursing
Undergraduate 3
01/13/2012

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Cards

Term
where is the ovum secreted from?
Definition
the ovary
Term
after its secretion from the ovary, how long is the ovum viable for?
Definition
24 hours
Term
after ejaculation how long are sperm viable for?
Definition
24-72 hours
Term
fertilization usually occurs where?
Definition
the ampule of the fallopian tube
Term
where must the fertilized egg travel for implantation?
Definition
through the fallopian tube into the uterus for implantation
Term
when does implantation occur?
Definition
9-11 days after fertilization
Term
when implantation occurs what is the structure of the egg and sperm called?
Definition
the fertilized egg is a 2 cell structure called a zygote
Term
what does the zygote secrete?
Definition
its own human chorionic gonadotropin (hCG, the hormone of pregnancy
Term
what is the hormone of pregnancy?
Definition
human chorionic gonadotropin (hCG)
Term
besides secreting hCG, what does the zygote also do?
Definition
sends messages to the corpus luteum to secrete estrogen and progesterone needed to maintain pregnancy until placenta takes over this function
Term
explain the three stages of fetal development
Definition
1. pre-embryonic (weeks 1-3)
2. embryonic (weeks 4-8) where there is rapid cell differentiation
3. fetal (many milestones occur)
Term
what is IMPERATIVE to explain to patients about weeks 4-8 of pregnancy?
Definition
that exposure to diseases, drugs, viruses, radiation may cause serious anomalies
Term
pre-embryonic period
Definition
-weeks 1-3
-begins with fertilization
-time of rapid cell division
Term
by the 3rd week, the end of the pre-embryonic period, what has formed?
Definition
the endoderm, mesoderm, and ectoderm and formation of the neural tube
Term
by the third week, what is the condition of the neural tube?
Definition
formation has begun, the ends are still open must fuses in the middle
Term
in what type of direction orientation does the baby develop?
Definition
cephalo-caudal or head to toe
and central to peripheral
Term
in the formation of a 3 week embryo what is prominent feature?
Definition
the brain because it forms more rapidly than the lower portions of the body
Term
embyonic period, week 4
Definition
-rapid cell differentiation
-dorsal part of the yolk sac is incorporated into embryo
-primitive gut begins to form
-neural tube closes at week 4
-embryo will exhibit primitive eyes, ears, jaws, and limb buds, kidneys
-day 28 a 2 chamber heart forms that beings to pump blood
-42 somites will develop into vertebral column and muscles
Term
when do women suspect that they are pregnant?
Definition
by the end of week 3, the pre-embryonic stage
Term
when does the neural tube close?
Definition
at week 4 during the embryonic period
Term
what occurs when the neural tube closes?
Definition
it forms the brain and spinal cord
Term
during what period does the embryo exhibit primitive eyes, ears, jaw, and limb buds, kidneys?
Definition
embryonic period (4-8 weeks after fertilization)
Term
in what period does a 2 chamber heart form and begins to pump blood?
Definition
in the 28th day or 4th week, the embryonic period
Term
the 42 somites that are present in the embryonic period will develop into what?
Definition
Term
when does spina bifida occur and why?
Definition
during the 4th week, in the embryonic period because this is when the neural tube closes
Term
embryonic period, week 5
Definition
-brain is larger than rest of body
-brain has 5 distinct areas and 10 pairs of cranial nerves
-cephalo-caudal growth continues
Term
embryonic period, week 6
Definition
-limb buds are extending
-MS developing
-heart has 4 chambers and are visible on real time ultrasound scan
-liver beging to form blood
-ears begin to appear
-trachea, bronchi, and lung buds developing
-upper lip and oral and nasal passages are developing
-it is at this time that cleft lip will occur it is will
Term
at what period does cleft lip occur if it will?
Definition
embryonic period, week 6
Term
embryonic period, week 7
Definition
-ultrasound heart is visible
-face formed with tongue and palate folds
-optic nerve formed
-fused eyelids are visible
-diaphragm is complete
-internal productive organs are beginning to diffrentiate
-gender cannot be told
-begin to take on human appearance
-very small only seen under a microscope
-brain and head are still larger and more developed than the rest of body
Term
embryonic period, week 8
Definition
-fingers and toes are forming
-ear structure is formed but embryo cannot hear until week 22
-heart function and fetal circulation are fully functioning
-organ cells are differentiated
Term
when will the embryo be able to hear?
Definition
week 22
Term
what is the major milestone for embryonic period, week 8?
Definition
last week of embryonic period
ALL structures are full differentiated even though they are not all functional and are very primitive
Term
during the process of diffrentiation which is complete by week 8 of the embryonic period, what is the embryo susceptible to?
Definition
teratogens
Term
teratogens
Definition
environmental factors that can cause birth defects
Term
65% birth defects occur during this period
Definition
embryonic period, week 8
Term
by week 8, the end of the embryonic period, many women may not be aware that they are pregnant. why is this dangerous?
Definition
they should be in prenatal care to stop smoking, ETOH, and drugs
Term
when does fetal circulation begin?
Definition
4 week into gestation
Term
describe the circulatory path from the mother to the fetus?
Definition
from the placenta in the mother to the umbilical cord to the fetus
Term
lifeline between the fetus and placenta
Definition
umbilical cord
Term
three structures within the umbilical cord
Definition
1. umbilical vein
2. 2 umbilical arteries
Term
umbilical vein
Definition
carries oxygenated blood from the placenta of the mother to the fetus
Term
umbilical arteries
Definition
there are 2 of them; carry deoxygenated blood and wastes to the placenta in the mother
Term
what is so significant about the arteries and vein of the umbilical cord?
Definition
they carry the opposite kinds of blood that adult vessels carry, the vein carries the O2 blood while the two arteries carry the deO2 blood and wastes
Term
what are the 3 structures within the fetus that perform circulation within the fetus?
Definition
ductus venosus
ductus arteriosis
foramen ovale
Term
ductus venosus
Definition
helps bypass the fetal liver
Term
in the fetus does detoxification take place in the liver?
Definition
no, in the maternal placenta
Term
ductus arteriosus
Definition
bypasses around the pulmonary vessels
Term
does the fetus ever use respiration in utero?
Definition
no, only practices
Term
foramen ovale
Definition
a hole b/t the left and right atrium
after birth it will shut
Term
in the fetus, which side of the heart has more atrial pressure?
Definition
the right
Term
how do we increase the left atrial pressure of the babies heart after birth?
Definition
by clamping the cord
Term
the ductus venosus, ductus arteriosis
and foramen ovale are what type of structures?
Definition
temporary and designed only to work during the fetal period, after birth when they are no longer needed, they will close
Term
at what time would you expect male and female genitalia to become apparent?
Definition
weeks 9-12
Term
weeks 9-12
Definition
-male and female genitalia become apparent but no well defined
-heart sounds can be heard around week 10
-bone and tooth formation
-fingers and toes are distinguishable
-kidneys produce urine as practice urine that becomes part of the amniotic fluid, the kidneys are NOT filtering, the other portion of the amniotic fluid comes from mother
Term
weeks 13-19
Definition
-RAPID fetal growth
-digestive system produces meconium
-sucking and swallowing reflexes
-quickening movement
-arms and legs becoming larger
-more symmetry
-very large head
Term
can hear fetal heart tones with Doppler ultrasound
Definition
weeks 10-12
Term
meconium
Definition
black, tarry substance that grows in between the intestines to make sure that they do not collapse on each other and grow together
Term
when does quickening occur for the fetus?
Definition
week 16
Term
quickening movement
Definition
first fluttering of fetal movement, often missed because it is so light
Term
weeks 17-23
Definition
-begins to lay down lanugo
-develops vernix
-hearing around week 22
-fetal movement detectment
-alveoli of the lungs are complete
-swallows amniotic fluid
-brown fat starts to deposit
Term
lanugo
Definition
fine downy hair
Term
vernix
Definition
cheese like substance that protects baby from the fluid that he floats around in
Term
without vernix and lanugo what would happen?
Definition
the pruny effect of staying in fluid to long
Term
when are the fetal alveoli complete?
Definition
around week 24
Term
surfactant; when does the baby create it own?
Definition
a substance that can keep the lungs open
week 27
Term
brown fat
Definition
very vascular and helps baby to maintain body temperature at birth since fetus does not have ability to shiver
Term
weeks 24-27
Definition
-major organs are functional but not FULLY functional
-nostrils are open
-actively practicing resp movements
-survival is based on the level of surfactant in the lungs
-lengthening of arms and legs
-large head
-weighs about 600 grams
Term
does the fetus have an intra-utero respiratory exchange?
Definition
no, it is done by the placenta although by about 24-27 weeks the fetus is actively practicing
Term
what is so significant about the fetal surfactant?
Definition
survival is based on the level of surfactant in the lungs; it decreases surface tension since taking the first breath for the infant is VERY hard and takes alot of energy! if he has enough surfactant he can maintain air in his lungs between each breath or residual capacity but without surfactant, each breath is like his first breath, requiring alot of energy
Term
weeks 28-31
Definition
-weighs a pound and few ounces
-can evaluate lung maturity with amount of lethicin/sphingomyelin, L/S of 2:1 ratio is ideal
-responding to noises
-eyelids are open
-fingernails have developed
-subQ fat
-heavy vernix
Term
with each week as the fetus ages what happens to its viability?
Definition
it increases
Term
what lethicin/sphingomyelin ratio is ideal?
Definition
L/S of 2:1
Term
weeks 32-36
Definition
-chances of viability are high
-surfactant levels increasing
-increase in subQ fat
-less translucent and wrinkly
-organs function more efficiently
-fetus get messages to decrease the vernix, lanugo and amniotic fluid
Term
at around what time does the fetus get messages to decrease the vernix, lanugo and amniotic fluid?
Definition
weeks 35-36
Term
post maturity
Definition
born beyond 42 weeks of gestation
Term
is a 37 week old fetus a full term baby?
Definition
no, it is a near-term infant
Term
a near term infant
Definition
born at 37 weeks
continue to have problems: feeding, resp, temp reg
may develop learning disabilities
Term
full term infant
Definition
38-40 weeks of gestation
eyes and limbs are fully functional
skin smooth and supple
laying down fat tracks for temp reg
testes of normal male have fully descended into the scrotum
generally adapt quite well
Term
when does the placenta begin to break down?
Definition
around 41 weeks
Term
what measures are taken for a fetus that is in post maturity?
Definition
induction of labor
c-section
Term
risks with post maturity
Definition
-aging placenta deprives infant of nutrients and oxygen
-may lose weight
-risk for hypoxia
-may excrete meconium into amniotic fluid which may be aspirated and cause chemical pneumonia
-a decrease in amniotic fluid: oligohydramnios which is less than 500 cc which can cause the cord tangled or knotted or impede the circulatory path
Term
average baby has how much amniotic fluid?
Definition
1000-1500 cc
Term
what are the types of twins?
Definition
-dizygotic (fraternal, non identical)
-monozygotic (identical)
Term
dizygotic twins
Definition
2 ova that are released at the same time but are fertilized by 2 different sperm cells. they may be the same or different sex and have 2 placentas, amnions, and chorions in the bags that surround them
Term
monozygotic twins
Definition
are identical twins. it is ONE fertilized egg that splits into 2 before the 15th day after conception. will be the same sex, one placenta for them both, one chorion, but each will have their own amnion
Term
when does the placenta begin to form?
Definition
around implantation
Term
what are the functional parts of the placenta?
Definition
cotyledons
Term
cotyledons
Definition
functional parts of the placenta that are formed by endometrial spiral arteries
Term
during the formation of the placenta, what occurs to uteran capillaries? spiral arteries?
Definition
they become capped off.
the spiral arteries of the endometrium fill with maternal blood and form cotyledons
Term
intervillious spaces
Definition
found numerously on each cotyledon and allow blood to cross from mother to fetus and where waste product is crossed from fetus to mother
Term
maternal and embryonic circulation has begun to form
Definition
day 17
Term
functions of the placenta
Definition
gas exchange
nutrient exchange
waste removal
passive protection from disease by passing antibodies

endocrine hormone that picks up hCG and estrogen and progesterone from corpus luteum
Term
is there a direct mixing of maternal and fetal blood?
Definition
no
Term
in fetal circulation, where does the gas exchange take place?
Definition
at the cotyledons
Term
fetal membranes
Definition
amnion (inner) is continuous with umbilical cord
and chorion which is outer
Term
components of amniotic fluid
Definition
fetal urine
rest from mother
Term
purposes of amniotic fluid
Definition
-cushions fetus from impact
-temperature stability
-buoyancy for fetal movement
-keeps body parts from adhering to mother's body and symmetrical growth
Term
is spina bifida hereditary?
Definition
no
Term
minor form of spina bifida
Definition
spina bifida occulta
Term
define viability
Definition
ability of fetus to survive outside of womb
gestation of 20 weeks with weight of 500 grams or greater
Term
as pregnancy advances, breathing changes from abdominal to
Definition
thoracic
Term
during the third trimester, may women find they are out of breath when in a reclined position, what can be done to help?
Definition
place a pillow to elevate their head when reclining
Term
what is the optimal position for a pregnant women?
Definition
on her side because it allows for optimal blood flow
Term
factors that effect teratogenic potential
Definition
-timing of exposure
-amount/length of exposure
-varied susceptibility levels of organ system
-placental transfer
-individual variations
Term
class C drugs are unacceptable during pregnancy because
Definition
they cannot be tested on humans and therefore maybe harmful to a fetus
Term
well known teratogens
Definition
infections
radiation
env factors
ETOH, tobacco & drug use
Term
infectious agents that can be teratogenic
Definition
rubella
herpes
CMV
AIDS
hepatitis
Term
maternal hyperthermia
Definition
teratogenic
Term
ETOH and pregnancy
Definition
abstinence is CRITICAl
Term
FAS
Definition
fetal alcohol syndrome produces a baby that is small for gestational age, cranio-facial and cardiac anomalies, developmental delays,attention deficits,and is untreatable after birth
Term
smoking and pregnancy
Definition
enters mother's bloodstream and the baby gets the same amount of nictoine, cyanide, CO, and lead

can cause coughs in uteri
small infant for gestational age
low birth weight
increased misccariages and preterm babies
also increased incidence of learning defects
Term
radiation and pregnancy
Definition
mother should NOT have x-rays during the embryonic period
Term
anytime a mother takes a drug, most drugs
Definition
crosses the placenta and exposes the baby
Term
babies who are exposed to illegal drugs
Definition
jittery
shrill cry
hyperactive
vomiting
diarrhea
low birth weight
learning deficits
same physiological but more due to small size
Term
antenatal testing
Definition
ultrasound
nuchal translucency
doppler flow
alpha fetal protein screening
chorionic villus sampling
amniocentesis
Term
ultrasound
Definition
uses high frequency sound waves
gives real time scanning
determines: # of fetuses, presence/absence of uterine/placental abnormalities, date pregnancies
Term
what can be observed with an ultrasound
Definition
fetal movements, breathing, heart viability
Term
nuchal translucency
Definition
an ultrasound to determine and examine the edema or fluid buildup in fetal neck, time is 10-14 weeks, used for early examination. increased edema is associated with cardiac problems, diaphragmatic hernia, and genetic abnormalities
Term
what are the criteria for a nuchal translucency exam?
Definition
done by a skilled sonographer
and fetus must be in good position (neck must be in good visible position)
Term
doppler flow assessment
Definition
allows the visualization of fetal blood as it flows through the umbilical cord vessels. done around 15 weeks, and to check for intrauterine growth restriction. if fetus has minimal blood flow, it can result in growth restriction
Term
what are the risks and side effects of ultrasound, nuchal translucency, and Doppler flow testing?
Definition
none known
Term
alpha fetal protein screening
Definition
invasive where mother's blood is drawn to examine amount of maternal blood levels of alpha serum protein to identify abnormal levels: low=chromosomal abnormalities, high=neural tube defects.
only a SCREENING tool! if abnormal results are detected they will be verified with more testing: ultrasound (high) or amniocentesis (low). has many false positives for this exam
Term
alpha fetal protein screening is often done at what time and why?
Definition
15-20 weeks to give her options and time to decide whether the pregnancy will be maintained based on the results
Term
chorionic villus sampling
Definition
an early test
the chorionic villi are the finger like projections for the blood to diffuse across and are part of the basic functional unit of the placenta, the cotyledons

can be done at 10 weeks
findings are available early for parent decision

it detects chromosomal problems and genetic problem

recommended for high risk pts like those with children with previous Down's syndrome or genetic abnormalities
Term
1st trimester alternative to amniocentesis
Definition
chorionic villus sampling
Term
if during chorionic villus sampling there is a high risk for specific abnormalities or chromosomal problems what will happen
Definition
a high risk perenatologist will be brought in
Term
techniques of chorionic villus sampling
Definition
1. transcervical aspiration under direct vision with real time sonography. where they do it through the cervix with the ultrasound guiding the movement
2. transabdominal with ultrasound
Term
advantages of chorionic villus sampling over amniocentesis
Definition
performed earlier (10-12 weeks)
rapid result return (within 48 hours)
Term
risks of chorionic villus sampling
Definition
risk for infection and small rate of pregnancy loss, mixing of fetal and maternal blood (for Rh situation)
Term
after an invasive procedure all Rh- mothers are given
Definition
Rhogam
Term
amniocentesis
Definition
aspiration of amniotic fluid from the amniotic sac for examination
Term
amniocentesis tests and looks at
Definition
examines fetal cells
chromosomal ration
LS ratio
test for hemolytic disease
genetic makeup of fetus
Term
to prepare for amniocentesis
Definition
1. ultrasound is used to locate the fetus
2. identify largest pocket of fluid
3. skin is prepped with antiseptic and a 3-4 inch needle is inserted
4. 20 cc fluid is drawn
5. is painless due to anesthetic
Term
amniocentesis is done when?
Definition
after 15 weeks of gestation
Term
disadvantages of amniocentesis
Definition
cells take 10 days to grown
test after 15 weeks of gestation
Term
when is genetic sex determined?
Definition
conception
Term
what are the two components required for conception?
Definition
spermatozoon (X or Y) and an ovum (X)
Term
puberty
Definition
refers to the time during which the reproductive organs become fully functional
Term
when does puberty take place?
Definition
late childhood and early adolescence
Term
primary sex characteristics
Definition
maturation of ova in the ovaries and sperm in the testes
Term
secondary sex characteristics
Definition
changes in other systems that differentiate females from males but do not directly relate to reproduction
Term
GnRH
Definition
gonadotropin releasing hormone; is released by the hypothalamus and gradually increases at ages 9-12 until it slowly reaches a level that stimulates the anterior pituitary to increase its production of follicle stimulating hormone (FSH) and luteinizine hormone (LH). in response to increases of FSH and LH the ovaries increase production of sex hormones and begn maturing gametes
Term
the secretion of FSH and LH in response to GnRH, what is released by the ovary?
Definition
estrogens and progesterones
Term
the release of estrogens and progesterones by the ovaries in response to the release of FSH and LH what occurs in females?
Definition
breast development
Term
first noticeable change of puberty and girls followed by what
Definition
breast development (8-13) then menstruation (9-16 years or 2-2.5 years after breast development)
Term
girls grow taller for several years during early puberty is response to estrogen stimulation. when does this growth spurt begin?
Definition
about 1 year after breast development
Term
estrogen's effect in puberty
Definition
1. causes growth spurt 1 year after breast development
2. cause epiphyses or growth areas on bone to eventually stop growth in height
Term
menarche
Definition
first period
Term
primary amenorrhea
Definition
delayed onset of menstruation if they have not begun within 2 years after the onset of breast development or by age 16 or if the girl is more than 1 year older than when her mom or sisters began their period
Term
secondary ammenorrhea
Definition
absence of period for at least 2 cycles after regular cycles have been established for 6 months
Term
both 1o and 2o amenorrhea are common is what type of women?
Definition
thin
Term
atheltic woman, thin woman, those that suffer from eating disorders, or ballet dancers may have too little what to produce enough sex hormones to stimulate ovulation and menstruation?
Definition
fat
Term
LH and FSH in males stimulate the secretion of testosterone and eventually causes
Definition
spermatogenesis in the maturing adolescent
Term
first outward sign of male puberty is
Definition
growth of the testes (9.5 yoa)
Term
what causes epiphysis union with the shaft in males?
Definition
testosterone
Term
climacteric
Definition
transitional period starting as female fertility declines and extends through menopause and the postmenstrual period
Term
age of climacteric
Definition
40-50
Term
menopause
Definition
last menstrual period
Term
vulva
Definition
collectively, all the female external reproductive organs: mons pubis, labia majora and minora, clitoris, structures of vestible and perineum
Term
vaginal introitus
Definition
vaginal opening
Term
are the labia minora covered in hair
?
Definition
no they are highly vascular and respond to stimulation by becoming engorged in blood
Term
vestibule
Definition
organs enclosed by the labia minora such as urinary meatus, vaginal introitus, and ducts of Skene's and Bartholin's glands
Term
Skene's or periurethral glands
Definition
provide lubrication for the urethra
Term
Bartholin's glands
Definition
provide lubrication for the vaginal introitus, particularly during sexual arousal
Term
perineum
Definition
area from the forchette to the anus
Term
internal female reproductive organs
Definition
vagina, uterus, fallopian tubes,and ovaries
Term
all of the internal female reproductive organs are supported by the
Definition
bony pelvis
Term
vaginal fornix
Definition
pouch like structure where the vagina meets the uterine opening (cervix) there are three: ant, post, lat
Term
T or F each month the uterus prepares for pregnancy even if it does not occur
Definition
true
Term
three divisions of the uterus
Definition
corpus
isthmus
cervix
Term
corpus
Definition
body or upper portion of the uterus, the upper corpus is the fundus
Term
isthmus
Definition
narrower transition zone that is between the corpus and cervix, during pregnancy it elongates and becomes the lower uterine segment
Term
cervix
Definition
tubular neck of the lower uterus that will thin and dilate during labor to allow the fetus to leave the uterus and enter the vaginal canal, has 2 os or openings, the internal os then the cervical canal, then the external os
Term
before and after birth what is the condition of the external os of the cervix?
Definition
before round and smooth
after irregular, slitlike with tags of scar tissue
Term
3 layers of the uterus
Definition
endo,myo, and perimetrium
Term
perimetrium
Definition
outer peritoneal serous tissue that is laterally continuous with the broad ligaments
Term
myometrium
Definition
muscular layer of the uterus, more muscle is concentrated towards the top and decreases towards the cervix
Term
layers of muscle in the myometrium
Definition
outer: longitudinal fibers-found mostly in the fundus and work to expel the fetus toward pelvic outlet

middle: figure 8 fibers that contract AFTER birth to compress blood vessels that pass between them to limit blood loss

inner layer:circular fibers that form contrictions where the fallopian tubes enter the uterus and surround the internal cervical os and promote normal implantation
Term
endometrial layers
Definition
1. basal layer is closest to the myometrium and regenerates the functional layer after each period or childbirth
2. functional layer is above the basal layer and vessels, and glands are in it and are all expelled shed during the period or after child birth in lochia
Term
oviducts
Definition
fallopian tubes
Term
fallopian tubes
Definition
form a pathway for ovum to travel from the ovary to the uterus
Term
where does fertilization occur?
Definition
in the fallopian tubes
Term
female gonads or sex glands
Definition
ovaries
Term
functions of the ovaries
Definition
release of sex hormones such as estrogen and progesterone and maturation of the ovum during each reproductive cycle
Term
why do the ovaries secrete estrogen and progesterone each cycle?
Definition
to prepare the uterine lining
Term
t or f: at birth the ovaries contain all the ova ever needed?
Definition
yes true
Term
why is the menstrual cycle an important marker for the reproductive cycle?
Definition
it marks the beginning and the end if pregnancy does not occur
Term
duration of female reproductive cycle
Definition
28 days
Term
the female reproductive cycle is divided into two cycle what are they?
Definition
ovarian
uterine endometrium
Term
ovarian cycle
Definition
when GnRH is released from the hypothalamus, it stimulates the release of LH and FSH from the ant-pituitary gland which stimulates the ovaries to mature and release an ovum and secrete additional hormones to prepare the endometrium for implantation with a fertilized egg there are 3 phases to the ovarian cycle: follicular, ovulatory, and luteal
Term
three phases of the ovarian cycle:
Definition
follicular, ovulatory and luteal
Term
follicular phase of the ovarian cycle
Definition
is the first phase; involves maturation of an ovum and occurs on the first day of menstrauation and lasts to day 14 of a 28 day cycle
Term
ovulatory phase of the ovarian cycle
Definition
occurs around midway (day 14) of the 28 day cycle, includes release of the mature ovum through the rupturing of a mature follicle
Term
ovulation marks the beginning of what phase?
Definition
luteal phase of the ovarian cycle
Term
luteal phase
Definition
occurs from day 14 of the 28 day cycle. the remaining cells of the old follicle persist for 12 days as a corpus luteum. the corpus luteum secretes estrogen and progesterone to prepare the endometrium for a fertilized ovum.

if the ovum is fertilized then it releases chorionic gonadotropin to cause the corpus luteum to persist to maintain an early pregnancy

if ovum is not fertilized then all levels fall and menstruation will occur and the uterine lining will break down
Term
corpus albicans
Definition
replaces the corpus luteum and is a fibrous tissue
Term
three phases of the uteral endometrium during the female reproductive cycle
Definition
proliferative
secretory
menstrual
Term
proliferative phase of the endometrial cycle
Definition
occurs as the ovum matures and is released. occurs during the first half of the ovarian cycle. is when the basal layer of the endometrium mutiply to form new endometrial epithelium, glands and vessels and as ovulation approaches the endometrial glands will secrete a thin stringy mucus that aids in the entry of sperm into the uterus
Term
secretory phase of the endometrial cycle
Definition
occurs during the last half of the ovarian cycle as the endometrium is prepared to recieve a fertilized ovum with stores of glycogen, protein, and lipids and minerals
Term
menstrual phase of the endometrial cycle
Definition
if fertilization does not occur then the corpus luteum will regress and the endometrium will become ischemic and necrotic and begin to slough off while the basal layer remains. this produces the menstrual flow and lasts about 5 days
Term
about how many cc of blood does a woman lose in a menstrual cycle?
Definition
40
Term
during most of the female reproductive cycle the mucus of the cervix is thick, scant and sticky. but just before ovulation it becomes
Definition
thin, clear and elastic to promote the entrance of sperm
Term
Spinnbarkeit
Definition
elasticity of the cervical mucus; woman can assess to either avoid or promote contraception
Term
are the breasts involved in reproduction?
Definition
no but they secrete milk through the milk ducts to nourish the infant after birth
Term
alveoli
Definition
small sacs that contain acinar cells to secrete milk
Term
acinar cells
Definition
extract necessary nutriets from maternal blood and manufacture milk when it receives message from ant pit gland
Term
what surrounds the alveoli to contract and eject the milk into the ductal system when signaled by secretion of the hormone oxytocin from the posterior pituitary gland
Definition
myoepithelial cells
Term
the alveoli drain into
Definition
lactiferous ducts
Term
when the lactiferous ducts come under the areola they are larger and are called
Definition
lactiferous sinuses
Term
what are the effects of estrogen, progesterone, and prolactin during and after pregnancy in regards to milk production?
Definition
during pregnancy high levels of estrogen and progesterone from the placenta stimulate growth of alveoli and duct system. prolactin stimulates milk production but the est and pro inhibit it but this stops after birth where active milk response takes place in response to the infant's suckling while breast feeding
Term
external male reproductive organs
Definition
penis
scrotum
Term
functions of penis
Definition
urination
deposits semen in vagina during coitus
Term
main function of the scrotum
Definition
keep the testes cooler than the rest of the body
Term
muscle that contracts and dilates to move testicles too and from the body for warmth and coolness
Definition
cremaster muscle
Term
what is the time frame that a woman has to get pregnant and NOT place her baby at risk for Rubella?
Definition
after 28 days of getting a Rubella vaccine the chance of the baby getting Rubella is unlikely
Term
to avoid malignant hyperthermia, what are some guidelines?
Definition
no more than 10 minutes in a sauna or hottub

being is exposed to temperatures of 100 F or higher is bad
Term
all women of childbearing age should take how much mg of folic acid a day even before conception?
Definition
0.4 mg
Term
genetic counseling is directive?
Definition
no, it is nondirective
Term
the ideal time to provide genetic counseling
Definition
before conception so that the childbearing couple has more options if risks are identified
Term
graafian follicle
Definition
small sac within the ovary that contains the maturing ovum
Term
corpus luteum
Definition
Graafian follicle cells remaining after ovulation that produce estrogen and progesterone
Term
nidation
Definition
implantation of the fertilized ovum (zygote) in the uterine endometrium
Term
oogenesis
Definition
formation of a gametes (ova) in the female and sperm in the testes of a male
Term
release of a mature ovum from the ovary
Definition
ovulation
Term
fetal structure that provides nourishment and removes wastes from the developing baby and secretes hormones necessary for the continuation of pregnancy
Definition
placenta
Term
gametogenesis requires what type of division?
Definition
meiosis; reduction division resulting in haploids
Term
contents of a haploid gamete cell
Definition
22 autosomes and 1 sex chromosome
Term
crossing over
Definition
the exchange of material between two gametes from the mom and dad to allow genetic variation
Term
when the sperm and ovum unite what happens to the halves?
Definition
they unite as one to produce 23 PAIRS of chromosomes
Term
primitive ova
Definition
oogonia
Term
explain oogenesis
Definition
begins during prenatal lfe when primitive ova (oogonia) multiply by mitosis. each oogonium contains 46 chromosomes. before birth these oogonia enlarge to form primary oocytes that are each surrounded by follicular cells.these are called primary follicles. the primary oogonium begins its first meiotic division during fetal life but does not complete it until puberty. the primary follicle and its oogonium still has 46 chromosomes and will remain dormant during childhood. by the 30th week of gestation the female fetus has all the ova she will ever have and many of them will regress during childhood, but at puberty some prmary follicles present at birth will begin maturing this will continue on into climacteric
Term
in oogenesis, one primary oocyte results in a
Definition
single mature ovum
Term
when a mature ovum is released from the ovary, it is surrounded by what 2 layers? why?
Definition
zona pellucida and cells of the corona radiata to protect the ovum from being penetrated by more than one sperm
Term
for fertilization to occur the sperm must penetrate the
Definition
zona pellucida and cells of the corona radiata to reach the ovum's nucleus
Term
spermatogenesis begins and is completed...
Definition
during puberty and takes 70 days to complete
Term
how long can ovum survive after ovulation? sperm?
Definition
both about 24 hours but sperm can spend up to 80 hours
Term
fertilization usually occurs where?
Definition
in the distal third of the fallopian tube or the ampulla near the ovary
Term
whether it is fertilized or not, when will the ovum enter the uterus?
Definition
3 days after ovulation
Term
explain the preparation for conception in a female
Definition
several oocytes begin to mature under he influence of FSH and LH from the ant pit. each maturing oocyte is contained within a sac called a graafian follicle which produces estrogen and progesterone to prepare the endometrium. one follicle will outgrow the others and be released and leave behind the graafian follicle which will develop into the corpus luteum which will maintain high estrogen and progesterone levels to make final prep for uterine lining
Term
seminal fluid
Definition
protects and nourishes the sperm from the acidic environment of the vagina
Term
t or f, seminal fluid enters the vagina
Definition
false, only sperm cells enter the vagina, seminal fluid remains at the cervix
Term
capacitation
Definition
sperm are not automatically ready to penetrate the ovum,they undergo changes while they are traveling to be able to penetrate the layers.

a glycoprotein coat and seminal proteins are removed from the acrosome
Term
acrosome
Definition
tip of the sperm head
Term
after capacitation
Definition
the sperm are more active and can penetrate the 2 outside layers of the ovum although they look the same
Term
besides capacitation, what else must the sperm do?
Definition
release hyaluronidase and acrosin to digest through the two layers surrounding the ovum
Term
what are the 3 things that happen after the entry of a spermatozoon into the ovum?
Definition
1. the zona pellicuda changes due to the zona reaction to prevent other sperm from entering

2. cell membranes of the ovum and sperm fuse and breakdown to allow the contents of the sperm head to enter the cytoplasm of the ovum

3. ovum will complete meiosis
Term
when is a fertilized egg considered a zygote?
Definition
4 days after conception
Term
morula
Definition
solid ball of 12-16 cells
Term
the outer cells of the morula secrete fluid forming a what?
Definition
blastocyst which is sac of cells with an inncer cells mass placed off center
Term
in a blastocyst, what will the inner and outer cells develop into
Definition
inner-fetus
part of the outer-placenta and fetal membranes
Term
when the blastocyst contains about 100 cells it enters the
Definition
uterus
Term
after the 100-cell blastocyst enters the uterus, how long will it linger before implantantion? why?
Definition
2-4 days; because the endometrium is in the secretory phase, secreting rish fluids to nourish the conceptus before placental circulation is established
Term
nidation is a gradual process that occurs between days
Definition
6-10 after conception
Term
production of hCG causes
Definition
the corpus luteum to continue secreting estrogen and progesterone until the placenta takes over this function
Term
where should nidation ideally occur?
Definition
in the upper posterior uterus
Term
chorionic villi and decidua basilis and their relation to the placenta
Definition
chorionic villi are tiny projection on the surface of the conceptus extending into the decidua basilus (endometrium). this will become the fetal side of the placenta and the decidua basilis will become to maternal side of the placenta
Term
before the placenta develops how is the embryo nourished?
Definition
through diffusion
Term
spotting
Definition
small amount of bleeding that occurs near the time of expected menstruation but is really due to nidation
Term
basic structures of all major body organs are completed during this period
Definition
embryonic period
Term
when does conception occur in relation to the LMC?
Definition
2 weeks after the LMC
Term
the fertilization age is how much shorter than the gestational age?
Definition
2 weeks
Term
maternal corticosteroids may be given such as ________ before birth to accelerate surfactant production in the preterm fetus likely to be born before 34 weeks
Definition
betamethasone
Term
axillary structures that sustain pregnancy and maintain prenatal development
Definition
placenta
umbilical cord
fetal membranes
Term
functions of placenta
Definition
metabolic
endocrine
transfer
Term
where is the umbilical cord usually inserted?
Definition
in the center of the fetal side o the placenta
Term
3 layers of the decidua (formerly the endometrial lining
Definition
decidua basilis: maternal placenta
decidua capsularis and parietalize
Term
do fetal and maternal blood mix?
Definition
no, but they pass near each other, exchange of substances occur within the intervillous spaces through the spiral arteries
Term
why is blood mixing bad?
Definition
fetal and maternal blood may not be compatible
Term
substances that the placenta synthesizes for the embryo
Definition
glycogen
cholesterol
fatty acids
Term
types of antibodies transferred from mother to fetus via the placenta
Definition
immunoglobulin G (IgG)
Term
when does the newborn begin to produce antibodies?
Definition
a few months after birth
Term
type of immunity involving IgG transfer from the placenta to embryo
Definition
passive immunity that protects baby from diseases that the mother is immune to such as measles
Term
most plentiful estrogen produced during pregnancy
Definition
estriol
Term
several hormones produced by the placenta necessary for normal pregnancy
Definition
hCG: causes the corpus luteum to keep producing estrogen and progesterone

testosterone: if a Y chromosome is present

human placental lactogen or human chorionic somatomammotropin promotes normal nutrition and fetal development and decreases insulin sensitivity and glucose use in mother to give more glucose supply to fetus

estrogen: enlargement of uterus, breasts and growth of ductal systems

progesterone: secretory changes in endometrium, change in decidua or endometrial cells, reduces muscle contraction to prevent spontaneous abortion
Term
amnion and chorion relative locations
Definition
amnion is the inner
chorion is outer
Term
runs continuous with the umbilical cord
Definition
amnion
Term
functions of the amniotic fluid
Definition
cushion
temperature stability
allowing symmetric development
preventing membrane adhesion to body parts of fetus
allwing room and buoyancy
Term
course of fetal blood circulation
Definition
from the fetal heart to the placenta for exchange of nutrients, gases, and wastes and then back to the fetus for delivery to fetal tissues
Term
cushions the umbilical cord to prevent obstruction due to pressue
Definition
Wharton;s jelly
Term
antepartum
Definition
time of pregnancy before labor
Term
reasons for antepartum fetal assessment
Definition
detect congenital anomalies
evaluate condition of fetus
Term
levels of obstetric ultrasound
Definition
standard (basic): general survey of fetus, placenta, and amniotic fluid

specialized (comprehensive): done if abnormalities are found during standard scan

limited: done to address a specific question like fetal presentation
Term
when can an embryo be seen after the LMC
Definition
5-6 weeks
Term
CRL
Definition
crown rump length
Term
fetal viability is confirmed by observation of the fetal heartbeat which is visible with the CRL is about
Definition
5mm
Term
what position must the woman be in for a transvaginal ultrasonography?
Definition
lithotomy
Term
which type of ultrasonography are more commonly used in the 2nd and 3rd trimesters?
Definition
transabdominal
Term
is it very accurate to try to determine gestational age after the 1st trimester? what can be done instead?
Definition
not really.
1. multiple measurements can be calculated by a computer
2. if 24-32 weeks, 2 or 3 ultrasounds can be taken to measure growth curve
Term
why is an accurate gestational age necessary for testing the level of maternal serum alpha-fetoprotein (MSAFP)?
Definition
because the level of AFP is altered by fetal age and number of fetuses
Term
Doppler sonography
Definition
an ultrasound assessment of blood flow to identify abnormalities
Term
AFP
Definition
alpha fetal protein is the predominant protein in the fetal plasma and is synthesized in the embryonic yolk sac, developing fetal liver, and GI tract
Term
most common open NTD: neural tube defects:
Definition
anacephaly: cranial vault is absent and mose the brain is undeveloped

spina bifida: includes
meningocele: the meninges protrude from the spinal canal
myelomeningocele: the spinal cord and meninges protrude through the defect and extensive nerve damage is expected
Term
is spina bifida occulta an open NTD?
Definition
no and it may cause no problems
Term
is MSAFP testing diagnostic or screening?
Definition
screening, if results are abnormal then further testing will take place
Term
low levels of AFP is associated with
Definition
chromosome defects such as trisomy 21 (Down's syndrome)
Term
the risk of having a child with a chromosome defect rises sharply after age
Definition
35
Term
what other two markers have been added to MSAFP testing to screen for chromosomal abnormalities?
Definition
unconjugated estroil and hCG
Term
triple screen
Definition
screening for trisomy 21, and 18 by testing levels of MSAFP, unconjugated estroil and hCG also placental hormone inhibin A is being added
Term
a triple screen is considered positive if
Definition
MSAFP and estriol are low and hCG is high
Term
in what methods can CVS occur?
Definition
transabdominal or transcervical however transcervical is more comfortable but produces light bleeding
Term
position to perform a CVS transcervically?
Definition
lithotomy
Term
patient education after a CVS
Definition
-may need to rest for a few hours after
-sex may be limited for a few days
-light spotting may occur
-may be given RhoGAM afterwards
Term
purpose of amniocentesis midtrimester vs in the 3rd trimester
Definition
mid: identify chromosomal abnormalities

3rd: determine fetal lung maturity ande evaluate condition when the woman has Rh isoimmunization
Term
PUBS
Definition
percutanous umbilical blood sampling or cordocentesis involves the aspiration of fetal blood from the umbilical cord from prenatal diagnosis and therapy
Term
antepartum assessment goals
Definition
-estimate delivery date or EDD/EDC
-evaluate treatment plan and risk level
Term
3 signs of pregnancy
Definition
presumptive
probable
positive
Term
presumptive signs
Definition
subjective explanations of how she feels
they are the least reliable since they can caused by other reasons besides pregnancy

they are:
amenorrhea
n/v
fatigue
urinary frequency
breast and skin changes
fetal movement "feeling"
Term
probable signs
Definition
are objective
are documented by examiner

are:
cervical changes (Chadwick's sign)
cervical softening (Goodell's sign)
ability to move cervix (McDonald's sign)
ability to palpate fetal outline
home pregnancy tests

can still be caused by other factors
Term
positive signs
Definition
auscultation of fetal heart with Doppler at 10-12 weeks or with fetoscope at 18-20 weeks

fetal movement felt by examiner

visualization by sonographer
Term
gravida
Definition
a woman who is or has been pregnant
Term
para or parity
Definition
number of pregnancies that have gone past 20 weeks
Term
term
Definition
birth that occurs between 38-42 weeks
Term
preterm
Definition
birth that occurs between 20-37 weeks
Term
abortion
Definition
termination that occurs before 20 weeks
Term
living
Definition
pregnancy carried beyond 24 weeks
Term
GP
Definition
gravida/partity
Term
GTPAL
Definition
gravida
term
parity
abortion
living
Term
normal or average pregnancy duration
Definition
from LMP is 40 weeks of 280 days
Term
Nagele's rule
Definition
is used to calculate EDD
LMP-3 months+ 7 days
Term
psychological variables during the trimesters
Definition
1st:
M: may be ambivalent or worried about self. Accepts fetus

D: accept pregnancy

2nd:
M: baby is primary focus and seen as a separate entity their may be introversion. body and sexuality changes
D: Accepts fetus

3rd:
M: Vulnerable, dependence on support person
D: developing and accepting role as a father
Term
maternal tasks:
Definition
-seeking safe passage for her and baby: obtaining care of qualified provider and their advice
-securing acceptance
-learning to give up self
-commitment to child
Term
couvades
Definition
nausea and weight gain and other s/s that mother feels in first trimester
Term
effective antepartum care should begin when?
Definition
in the 1st trimester until birth
Term
initial assessment of antepartum mother
Definition
LMP and EDD
childhood disease
immunizations
allergies
contraceptive use
med/surg history
past pregnancies
labs
physical assessment
socioeconomic status
Term
subsequent visits of antepartum mother
Definition
0-28 weeks is q4weeks
29-36 weeks q2-3weeks
37+ weeks is weekly
Term
with each visit what must you collect from an antepartum mother?
Definition
VS
Wt
UA: Ck glucose/protein
glucose testing 1 hr tolerance
fundal height
monitor fetal HR and activity
Term
insufficient weight gain can cause
Definition
low birth weight
fetal & newborn mortality
preterm labor
Term
causes of insufficient weight gain
Definition
poor caloric/nutrient intake
smoking or drug abuse
hypemesis
Term
at risk for insufficient weight gain
Definition
young
unmarried
uneducated
poor
Term
excessive weight gain can cause
Definition
macrosomia: large baby
prolonged labor
birth trauma
cesarean birth
Term
infant weight of 6.5-8.8 lbs
Definition
lowest fetal death rate
Term
recommended weight gain for a person with a normal BMI of 19.8-26? how is this weight gain distributed per trimester?
Definition
25-35 lbs.
1st: 3.5 lbs
2nd & 3rd: 0.88 lbs a weeks
Term
dietary needs of pregnant woman
Definition
2200-2500 cal/day
protein: 71 g/day: fish,meat, tofu, poultry, rice and beans

carbs: 175 g from complex carbs, high fiber
Term
special vitamins and minerals
Definition
vitamin A
folic acid
iron
calcium
Term
vitamin A
Definition
fat soluble
so it is stored so there is a risk for too much
vegeterians need to be careful to avoid fetal defects due to too much
Term
foods with folic acid
Definition
beans, peanuts, oranges, asparagus
Term
iron
Definition
30 mg to increase RBC and increase Fe stores for baby.
may cause n/v
dont take with coffe, tea, or with Ca to prevent inhibition
best absorbed during sleep
increased absorption with Vitamin C
Term
foods with iron
Definition
meats
legumes
eggs
grains
raisins
spinach
Term
calcium
Definition
needed for bone formation and cellular and neuromuscular function. transferred to fetus in 3rd trimester

1300 mg if under 19
1000 is older than 18
Term
foods with calcium
Definition
dairy, legumes, nuts, dried fruits, dark leafy vegetables, blackstrap molasses, soy
Term
special dietary needs
Definition
-adolescent:
be careful of junk food and non-compliance and assess peer pressure

-vegetarian: is possible healthily
know the specific restrictions.
high fiber foods can cause GI upset
assess for complete protein: legumes and grains
can get calcium from veggies and soy and iron from soy but may have decreased absorption due to lack of heme
may lack zinc and vit b12 and may need supplements
Term
uterus changes during pregnancy
Definition
60 g,10 ml
to
1000 g, 5000 ml
Term
uterus reaches its highest size around? drops?
Definition
36-38 weeks; 40 weeks
Term
ovaries changes during pregnancy
Definition
increase production of estrogen and progesterone which inhibit FSH and LH, ovaries cease ovulation
Term
effects of estrogen and progesterone on LH and FSH
Definition
inhibit their effects and during prgnnancym no ovulation can occur
Term
cervical changes during pregnancy
Definition
color-bluish (Chadwick's sign)
consistency-softening (Goodell's sign)
both are probable signs
mucus plug to protect fetus and membranes from infection
Term
vaginal and vulvar changes during pregnancy
Definition
softening and bluish discoloration, vaginal folds (rugae) become more prominent
mucus thickens
leukorrhea appearance to mucus due to WBC to protect cervix and uterus from infection
glucose levels increase which increases risk for vaginal and yeast infections
Term
breast changes during pregnancy
Definition
-increase in estrogen and progesterone
-increase in mammary ductal tissue causing breast to get larger
-increase in vascular prominence
-stretch marks
-nipples and areolae enlarge and erect
-montgomery tubicles produce sebaceous material which are a natural lubricant for breast
Term
cardiac changes during pregnancy
Definition
-minor and non-permanent
-heart muscle enlarges
-heart sounds change: systolic murmur/split of S1
-blood volume increases from 1200-5000 ml
-RBC mass increases from 250 to 450 ml
-plasma volume increases to meet oxygen and nutrient demands from placenta. this increase is more pronounced than RBC mass, causing a pseudoanemia, Fe supp may be needed
-WBC increase during and after delivery
-CO increases
-peripheral vascular resistance is reduced
-diastolic BP drops
Term
pulmonary changes due to pregnancy
Definition
result of:
increased O2 consumption
hormonal changes
enlarging uterus

respiration depth and rate increase to meet needs of fetus
-increased progesterone causes minor hyperventilation, reduces airway resistance, increases sensitivity to CO2
-estrogen increases vascularity in mucus membrane and edema in nose: congestion and nose bleeds
-ribs flare due to the diaphragm be pushed up
-breathing more thoracic causing dyspnea t times
Term
GI changes due to pregnancy
Definition
-increased estrogen levels causes hyperemia: bleeding of the gums and increased salivation

-increased progesterone relaxes smooth muscle causing constipation, heartburn and nausea
Term
urinary tract changes due to pregnancy
Definition
-freq and urgency of urination
-progesterone relaxes smooth muscle tone
-GFR increases
-weight of baby puts pressure on bladder
Term
skin changes due to pregnancy
Definition
-increased circulation which encourages sweat and sebaceous activity, causing the glow

-hormone changes can cause chloasma or the mask of pregnancy from increased pigmentation of the skin

-linea negra: line from umbilicus down to symphysis pubis and is temporary and will fade after pregnancy

variscosities may develop from the weight and pressure of the baby
Term
MS changes due to pregnancy
Definition
-relaxin and progesterone will relax joints and ligaments giving woman an altered sense of gravity, increasing frontal pressure making walking difficult, low back pain, lordosis of lower spin

fetal growth may cause diastesis recti or separation of abdominal muscles
Term
glucose and insulin changes due to pregnancy
Definition
1st T:
F: fetus draws glucose and amino acids from mother
M: mother has decreased ability to synthesize glucose and insulin and blood sugar levels drop

2nd & 3rd:
F:placenta produces insulinase which reaks down insulin so more glucose is available to fetus for growth and carb matabolism

M: mother needs more glucose so glucose increases and pancreas produces more insulin. peak of insulin resistance is at 24-28 weeks so you need to perform a glucose screen
Term
danger signs to tell MD right away
Definition
vaginal bleeding
mmbrane rupture
swelling of fingers/face
continuous pounding headache
visual distubances: floating spots, blurred vision
chills or fever
painful urination
persistent or severe abdominal pain
change in frequency or strength of fetal movements
Term
nonstress test (NST)
Definition
used to assess fetal well being by measuring response of fetal heart to fetal movement

noninvasive
30-40 min
results are better if mom has not smoked recently
positioned in reclining chair or bed that is elevated at HOB and lying on left side and knees are bent

gather baseline VS
apply external monitoring equipment: ultrasound, tocotransducer
and event marker

data:
reactive: baseline of 110-160, long term variability, more than 2 accelerations of 15 bpm for 15 seconds in a 20 minute strip

nonreactive: does not meet reactive criteria in appropriate time

equivocal: adequate but not the criteria for reactive
Term
non stress testing interpretation
Definition
Term
pros and cons of NST
Definition
pros:
noninvasive
painless
no risk

cons:
false positive if baby is sleeping and healthy; if sleeping give mom organze juice, move into new position, or use sound
Term
vibroacoustic stimulation
Definition
can awaken baby
confirm nonreactive stress test

use ultrasound:
monitor fetal HR
apply artificial larnyx stimulation for 1 sec, if no response, repeat in 10 seconds
Term
vibroacoustic stimulation may not work if
Definition
may not work if there is a suspected hearing loss, test has been done to often, baby is exposed to too much sound
Term
contraction stress test
Definition
indirectly evaluate fetal oxygenation to further evaluate nonreactive nonstress test

goal is to get 3 recordable contractions that last 40-60 seconds in a 10 minute period

avoid contractions that are over 90 sec in freq and less than 2 minutes in frequency

can use possible unilateral nipple stimulation to trigger contraction or oxytocin challenge to cause contraction
Term
results interpretation of CST
Definition
negative- no late deceleration and this is reassuring

positive- greater than 50% have late decelerations

equivocal- not quite 50% have late decelerations, the uterus could be overstimulated
Term
pros and cons of CST
Definition
pros:
reassurance of NST findings
evaulate needs of compromised fetus

cons:
time consuming to get 3 contractions
tedious
errors in data interpretation
high cost
Term
biophysical profile (BPP)
Definition
uses ultrasound to assess 6 parameters of fetus include acute and chronic markers:

acute:
fetal HR
breathing movements
gross fetal movements
fetal tone
amount of amniotic fluid: long term chronic
placental grading

helps ID hypoxia and acidemia
Term
what does the BPP help identify
Definition
the biophysical profile (BPP) helps identify hypoxia and acidemia
Term
sequence of development for biophysical profile (BPP)
Definition
tone
movement
breathing
fetal HR
Term
sequence of actions when fetus under stress
Definition
is the reverse of sequence of development for biophysical profile (BPP):

late deceleration
accelerations disappear
no breathing movement
no gross movement
loss of tone
Term
strong indicator of prolonged fetal hypoxia
Definition
oligohydramnios
Term
pros and cons of BPP
Definition
pros
noninvasive
moderate cost
immediate results

cons
needs refined interpretation
application to outcomes need more establishment
Term
cordocentesis
Definition
needle is inserted into umbilical vein
ultrasound is used to guide
Fetal HR monintored for 30-60 minutes
Rh- woman is given RhoGAM to prevent sensitization
Term
maternal assessment of fetal movement or kick count
Definition
counts for 30 minutes 3 times a day lying on her side

notify MD if she has fewer than in 1 of the 30 minutes of a change in the type or characters
Term
maternal assessment of fetal movement or kick count pros and cons
Definition
pros:
noninvasive
not costly
early detection
mother participation

cons:
subjectivity
variables: fetal sleep, maternal drugs, time of day
Term
pain methods used in lamaze teaching
Definition
positioning:
-side lying
-standing up
-lying on back
-slow dancing
-rocking
-walking

relaxation
-effleurage
-massage

mental stimulation
-focal point/imagery/music

breathing
-slow paced breathing during 1st stage
-modified paced as contractions get stronger
-pattern paced involving blowing out to prevent pushing
-breath holding begins in 2nd stage of labor when we want the mom to push and hold breath
Term
maternal infections with greatest risk for fetal and neonatal harm
Definition
cytomegalovirus (CMV)
rubella
varicella sozter virus
hep B
HIV
Term
transmission types for viruses
Definition
vertical or horizontal
Term
vertical viral transmission
Definition
in utero by crossing placenta or during birth as ascending infection after rupture of membrane

include
-toxoplasmosis
rubella
CMV
herpes
hepatitis

outcomes:
birth defects
long term consequences
Term
horizontal viral transmission
Definition
acquired from family/staff/others or equipment

include:
staphylococcal
TB
CMV
Term
CMV

transmission

effect

nursing consideration
Definition
infection that usually occurs in females between ages of 15-35

transmission: transplacental, during birth, in breast milk

effect:
deafness, blindness in fetus/neonate, seizures, and mental retardation

nursing consideration:may not show s/s for months to years, there is ONLY supportive treatment, if if Dx in the first 20 weeks than a therapeutic termination may be considered
Term
rubella

transmission

effect

nursing consideration
Definition
transmission: transplacental

effect: deafness, mental retardation, cataracts, cardiac defects, IUGR: intrauterine growth retardation, microencephaly

nursing consideration: greatest risk for transmission is during the first trimester when organs are developing. if mother becomes pregnant this time, then 1/3 of mothers will have spontaneous abortion. infants of mothers with the virus during pregnancy can shed the virus for several months after birth

treatment: prevention!!!!!!!!! if a mother is non-immune she will receive a vaccine after she delivers and will need contraceptives to prevent pregnancy in the first month after receiving the vaccine
Term
chicken pox
Definition
varicella zoster
Term
varicella zoster

transmission

effect

nursing consideration
Definition
transmission: direct contact, resp tract, transplacental

effect:
1st TRI: small chance of congenital varicella syndrome

13-20 weeks:
limb hypoplasia
cutaneous scars
chorioetinitis
cataracts
microencephaly
IUGR

nursing consideration: in 1st trimester there is a small risk, greatest risk at 13-20 weeks: 1/3 will spontaneously abortion. infant with mothers with virus during pregnancy may shed virus for several months after birth. If maternal varicella develops more than 6 days before birth then maternal antibodies will protect fetus, however if less than 6 days before or 2 days after than antiobodies in neonate won't have time to develop and they may develop neonata varicella infection which is life threatening

PREVENTION:
immune globulin to mom and baby within 72 hours of birth and isolation if born to a mother + for varicella zoster
Term
herpes 1 and 2

transmission

effect

nursing consideration
Definition
transmission: vertical: transplacental and after ROM or during delivery

effects:
primary infections are more serious:
spontaneous abortion
IUGR
preterm labor

nursing consideration: if reccuring infection, complications for fetus are rare. no cure, may take acyclovir dueing preganncy, but it is taken with great caution. but primary infections can have devastating effects. if there are active lesions then c-section is recommended
Term
acyclovir
Definition
cat. c drug used for herpes 1 and 2
Term
neonatal herpes:

transmission

effect

nursing consideration
Definition
transmission

effect: rapid disease progression, infection with skin lesions. or may develop systemic herpes

those who develop systemic herpes are at a 50% risk for developing serious neuro complications

nursing considerations:
no cure
acyclovir therapy
post delivery observe infant for s/s infection, isolated (not from mother), avoid contact with lesions, do handwashing, prevent spreading! may breastfeed if there are no lesions on the breast
Term
hepatitis B

transmission

effect

nursing consideration
Definition
transmission: blood, saliva, semen, vaginal secretions, breast milk, transplacental

effect:newborns and children infected before 5 yo will become chronic carriers. chronic B infection develops in 90% of newborns. greater risk for chronic liver disease

nursing considerations:baby born with mom who is hep b+ will receive immunoglobulin as well as first HBV immunization, bath before injection, breast feeding is safe after vaccinations
Term
HIV

transmission

effect

nursing consideration
Definition
transmission: transplacental, during birth: infected blood and secretions, breast milk

effect: infants with a mother that is HIV+ have a 20-40% risk for developing the disease. s/s usually occur within the 1st year and include an enlarged liver/spleen and lymph nodes, failure to thrive, opportunistic infections, and bacterial infections

nursing considerations: will progress from HIV to AIDS more rapidly than in the adult.increase medications. breastfeeding is CONTRAINDICATED. education: encourage a healthy lifestyle for parents and for detox for drug abuse, or at least washing needles with soap, water, and bleach. mother should understand medication regime to slow progression and reduces risk for vertical transmission, deal with social isolation
Term
toxoplasmosis

transmission

effect

nursing considerations
Definition
a protozoan infection caused by toxoplasma gandhi

transmission: transplacental, poorly cooked meat, cat feces, and infected soil

effect:
maternal complaints: vague and sound like the flu

fetal: spontaneous abortion, 50% for developing congenital toxoplasmosos,may be no s/s at birth with a late onset of: chorioretinitis, deafness, neuro damage such as seizures, hydrocephalus, microcephaly

nursing considerations: educate mom on contaminants and instruct her to avoid touching the mucous membranes of the mouth and nose. some symptoms in neonate may take years to develop

therapeutic management:
prevention
hand washing
avoid contaminants
treatment during pregnancy to reduce infection risk
sulfonamides are most effective in a combination therapy
Term
group B strep

transmission

effect

nursing consideration
Definition
leading of life threatening perinatal infection in US

transmission:

effect:
early onset:
1st seven days of birth
can cause: sepsis, pneumonia, meningitis

late onset:
occurs after first 7 days
meningitis is most common form of infection and can cause permanent neuro damage

nursing considerations:
prevention:
taking maternal vaginal and anal cultures at 35-37 weeks, if + then give abx at least 2 doses before delivery, during delivery, abx given q4h

prenatal screening for any of these criteria:
-previous infant with GBS
-GBS in urine during preg.
-birth before 37 weeks
-maternal fever during labor over 100.4
-ROM greater than 18 hours

if present then treat with abx during labor
Term
TB

transmission

effect

nursing consideration
Definition
transmission airborne droplets

effect:

nursing consideration: screen with PPD if + they will receive INH/rifampin qday for 9 months. must be tx with multiple drugs for a prolonged time. if there is drug resistance than ethambutol will be added and vitamin B6/periodoxine to prevent fetal neurotoxicity while receiving medications

post delivery: infant skin test, prophylactic INH, repeat the test in 3 months, if - then INH is stopped, if + then give full course. isolation from mother is not necessary if mom's sputum is free of organisms. breastfeeding is ok, but check drug levels since the drugs are secreted in breast milk
Term
main goal with STD or STI
Definition
prevent further infection to newborn
Term
with chlamydia and gonorrhea we want to prevent
Definition
opthalmia neonatorium, so we out abx ointment in newborn eyes to prevent transmission
Term
candidiasis

transmission

effect

nursing considerations
Definition
transmission: at birth

effect: thrush, bacterial vaginosis (no none fetal effect) but is associated with preterm birth and postpartum endometritis

nursing considerations
Term
UTI

types

effect

nursing considerations
Definition
types:
asymptomatic bacteriuria
cystitis
acute pyelonephritis (more serious)


effect: can increase risk for preterm labor, develop septic shock, and adult respiratory distress syndrome. may worsen without treatment

nursing considerations: treat to prevent progression to more dangerous or fatal disease
Term
UTIs
Definition
Term
sepsis neonatorium
Definition
bacteria in bloodstream, is systemic and can be caused by group B strep, hemolytic strep, E.coli.

infants are already vulnerable due to their immature immune system, decreased reaction, and limited antibodies, spreads throughout the body. preterm and low birth weight makes them MORE susceptible

types:
early: develops within the first week and usually in 1st 24 hours. acquired through vertical transmission or labor complication. rapid progression and cause cause resp infections such as pneumonia and meningitis and other long term effects

late: develops after 1st week through horizontal transmission or exposure to organism, slower progression with lower mortality, often affects CNS

s/s:
-obscure
-low grade temp less than 97.6
-feeding and behavior changes
-resp problems
Term
sepsis neonatorium diagnostic tests and interventions
Definition
Dx tests: culture of blood and urine, CBC, glucose, CXR, IgM increase could indicate an infection in utero

Interventions: administering fluids IV, abx, O2, vent support, temp regulation, gavage feedings, glucose monitoring, prevent infection spread
Term
Braxton Hicks contractions
Definition
irregular, usually mild uterine contractions that occur throughout pregnancy and become stronger in the last trimester
Term
Chadwick's sign
Definition
bluish purplish discoloration of the cervix, vagina, and labia during pregnancy and become stronger in the last trimester
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