| Term 
 
        | Sounds that originate in the cochlea and propagate through the middle and outer ear. Measurable using sensitive microphones placed in the ear canal |  | Definition 
 | 
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        | Term 
 
        | -In the mid 1800s, German physicist Hermann von ___ observes that air-filled cavities are tuned to specific resonant frequencies
 -von Helmholtz believed that the auditory system was composed of these resonators (“harmonic oscillators”), which responded to the movement of the ___ ___
 -While not physiologically accurate, von Helmholtz was
 fundamentally correct that the cochlea acts as a ___ ___
 |  | Definition 
 
        | Helmholtz; basilar membrane; frequency analyzer
 |  | 
        |  | 
        
        | Term 
 
        | -In 1928, Georg von Békésy describes the ___ ___ in the cochlea -von Békésy disagreed with von Helmholtz: he did not believe it
 was possible for there to be cochlear resonators tuned ___ enough to account for high-frequency hearing loss
 |  | Definition 
 
        | traveling wave; precisely |  | 
        |  | 
        
        | Term 
 
        | -In ___, renaissance man extraordinaire Thomas Gold concluded that the resonant mechanisms proposed by von Helmholtz and the traveling wave of von Békésy were both components of the cochlear analyzer -Gold postulated an oscillating ___ mechanism that should be audibly perceptible
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | -In 1978 British scientist David Kemp reports measurement of ____ emissions from the ear. -In 1979, Kemp describes similar emissions produced ___ (without a stimulus)
 |  | Definition 
 
        | stimulated (evoked); spontaneously |  | 
        |  | 
        
        | Term 
 
        | A new auditory phenomenon has been identified in the acoustic impulse of the human ear…This component of the response appears to have its origin in some ___ mechanism probably located in the cochlea, responding mechanically to auditory stimulation, and dependent upon the normal functioning of the cochlea ___ process…It is tempting to suggest that one of the functions of the outer hair cell population is the generation of this ___ energy |  | Definition 
 
        | nonlinear; transduction; mechanical |  | 
        |  | 
        
        | Term 
 
        | In 1982, Scandinavian scientists N.J. Johnsen and colleagues describe ____ OAEs
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | -In 1983, Hallowell ___ describes the “cochlear amplifier” and speculates (correctly, as it turns out) on the origin of OAE signals -In 1985, American audiologist William ___ describes outer hair cell motility
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is the source of the energy for the cochlear amplifier?  The best hint that we have is the requirement that the outer hair cells be ___. This suggests a ___ function for OHC, with the efferent innervation providing a modulating influence, and perhaps a trophic function also. The large number of OHCs, ___ rows instead of one, may be an expression of the need for a large source of ___. |  | Definition 
 
        | intact; motor; three; power |  | 
        |  | 
        
        | Term 
 
        | -OAEs are believed to be by-products of the ___ ___ -No ___ involvement-Can be measured even when neural responses are ___ or when ___ nerve transmission is blocked
 -Related to normal functioning of OHC-____ to agents known to affect OHC function
 -Affected by alterations to the ___ innervation systems of OHC-Contralateral suppression, direct electrical stimulation of ___ fibers appear to affect OAE amplitude
 |  | Definition 
 
        | cochlear amplifier; neural; absent; VIII; Vulnerable; efferent; efferent |  | 
        |  | 
        
        | Term 
 
        | -In 1989, F.P. Harris, Brenda Lonsbury-Martin and colleagues at Baylor University systematically study ___ of distortion tones on DPOAE -In 1992, American hearing scientist Peter ___ describes threshold sensitivity and frequency tuning of the outer hair cells
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | You want 2 frequencies that are close together but not ___ ___, which is why f1 and f2 are separated by a ratio of ___. You don't want the 2 tones to look like ___ big peak, you want 2 ___ peaks. |  | Definition 
 
        | too close; 1.22; one; separate |  | 
        |  | 
        
        | Term 
 
        | Spontaneous OAEs: -No ___ needed
 -Present in less than ___% of humans. Comparable prevalence in newborns, children, and adults
 -More common in ___ than in ___.
 -No clear effect of ___ if hearing sensitivity is normal.
 -Frequencies tend to be stable over ___ periods of time. ___ frequencies are common. Amplitudes may ___ (e.g., middle ear effects)
 -Independent of ___
 |  | Definition 
 
        | stimulus; 70; females; males; aging; long; Multiple; fluctuate; tinnitus |  | 
        |  | 
        
        | Term 
 
        | Transient Evoked OAEs (TEOAE): -Measured following introduction of a ___ stimulus – click or tone burst
 -Evaluated in terms of ___, ___, and ___
 -___ in nearly all ears with normal sensitivity and ME function
 -ABSENT in nearly all ears with SNHL greater than __-__ dB HL
 |  | Definition 
 
        | transient (brief); amplitude; reproducibility; SNR; PRESENT; 30-50 [image]
 |  | 
        |  | 
        
        | Term 
 
        | Distortion Product OAEs (DPOAE): -Non-linear distortion produced by simultaneous introduction of tones at certain ___ ___
 -When f1 and f2 are close in frequency, they interact to produce energy at predictable ___ ___
 |  | Definition 
 
        | frequency ratios; discrete frequencies |  | 
        |  | 
        
        | Term 
 
        | What are some clinical applications of OAEs? |  | Definition 
 
        | noise/music exposure, monitor ototoxicity, assess suspected functional hearing loss, cochlear vs retrocochlear, CAPD, hearing screenings, assessment of tinnitus and hyperacusis, newborn hearing screening |  | 
        |  | 
        
        | Term 
 
        | What are some advantages of OAEs? |  | Definition 
 
        | doesn't require behavioral response, sensitive to OHC function, ear and frequency specific, can be sedated or asleep, no sound booth, good cross check, can be quick, portable, and relatively inexpensive |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | can be affected by noise, affected by ME disorder, doesn't provide info about IHC, can be abnormal with normal audiogram and vice versa, aren't detectable with HL >30-50 dB HL, not a true test of hearing, and doesn't measure neural auditory function |  | 
        |  | 
        
        | Term 
 
        | Probe Components: -DPOAE: ___ tubes. ___ stimulus drivers (f1 and f2), microphone
 -TEOAE: ___ tubes. ___ stimulus driver (transient), microphone
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Components of the OAE System: -Stimulus components: ___ generator, ____ circuitry, and ___
 -Measurement components: ___, Band-pass filter (Isolate energy at expected DP frequencies), ___, and Analog-to-digital converter which is housed in a computer or stand-alone device
 |  | Definition 
 
        | Signal; Amplifier/attenuator; Speaker; Microphone; Amplifier; |  | 
        |  | 
        
        | Term 
 
        | -OAEs are VERY ___-intensity signals -As a result, OAE devices require extensive ___ of the signal to extract the response from the noise floor
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are some sources of noise? |  | Definition 
 
        | microphone noise, ambient noise in the test setting, breathing, rubbing of the probe tube against clothing, jaw movements, muscle movements, and blood flow |  | 
        |  | 
        
        | Term 
 
        | Time-synchronous averaging: -Each time the stimulus is presented, the ___ in the ear canal is sampled
 -Starting point of the sample is ___ with the onset of the stimulus
 -Stimulus presented hundreds of times, with the sample averaged across each ___
 |  | Definition 
 
        | sound; synchronized; presentation |  | 
        |  | 
        
        | Term 
 
        | Averaging: -Assumption:  each time the OAE is sampled, it should be the ___
 -Therefore, any noise or artifact that does not recur in synch
 with the stimulus is noise, which will be random and eventually will ___ out
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are some actions you can take to minimize the noise effects on OAE recordings? |  | Definition 
 
        | -eliminate extraneous noise sources in test room -close door to test room
 -insert probe deeply
 -secure probe cord
 -instruct patient to remain quiet and still (if feasible)
 -position test ear away from equipment
 -modify protocol (to frequencies > 2000 Hz)
 |  | 
        |  | 
        
        | Term 
 
        | Are there ANSI standards for OAEs? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | How often should OAE units be checked? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | OAE Calibration-Frequency: -An electronic counter can be used to determine whether probe signals for distortion-product OAEs are ___ in terms of ___
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | OAE Calibration-Intensity: -In many cases, the OAE probe may be coupled to a 2-cc coupler (HA-type) and sound level meter with octave band filter to measure ___ and check for ___
 -For DPOAE, each stimulus channel must be measured ___
 -For TEOAE, SLM must be able to sample ___ noises
 |  | Definition 
 
        | intensity; distortion; independently; impulse |  | 
        |  |