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NYCPM-Indi-test4
question and answer
35
Microbiology
Graduate
08/15/2012

Additional Microbiology Flashcards

 


 

Cards

Term
what are dna viruses?
Definition
linear herpes, circular hepadna, linear adeno, circular papova, pavovirus linear, poxvirus linear
Term
what are single standed DNA viruses?
Definition

parvovirus-linear-non-envelope icosahedral

 

Term
what are double dna stranded virus-envoloped icosahedral?
Definition
linear herpes and circular hepadna
Term
what are double  DNA stranded virus non-envelop icosahedral?
Definition
linear adeno and circular papova
Term
what is enveloped-complex virus?
Definition
poxvirus (linear)
Term
What is the definition of viron?
Definition
self replicated circular RNA
Term
What is the definiton of Virusoids?
Definition
Replicating protein of virus based on host protein
Term
what is prion?
Definition
a defective protein found in infectious patients
Term
what is casid?
Definition
is the envelope of the virus
Term

what is casomer?

 

Definition
is the smallest unit of capid
Term

what is nucleocapsid?

 

Definition

capsid with nucleic acid

 

Term
what is icosahedral ?
Definition
is the icosahedral to make the icosahedral envelope
Term

what is helical capsid?

 

Definition
is the viral nucleic acid associated with protein envelope
Term
what is ambisence?
Definition
partial posive or negative standed
Term
tell me some thing about lipid envelope?
Definition
sensitive to heat, detergents, lipid solvents, alcohol
Term
how does viral enveloped protein function in term of viral penetrate patient?
Definition
to entry into host cells-peplomeres or spikes
Term
what is Hemagglutination and Hemadsorption assay?
Definition
to test if viral' protein agglutinate RBC
Term
What does Plaque Assay use for?
Definition
to determine infectious number of particle
Term
What is transformation foci?
Definition
 to assay in vitro by infecting monolayers
Term
What is permissive growth viruses?
Definition
permissive is cells are able to support replication of virus
Term
what is non-permissive viruses?
Definition
are cells not being to support virus replication
Term
What does Plaque Assay?
Definition
to determine infectious number of particles
Term
What is transfomation foci?
Definition
to count the number of transformaiton focal area
Term
What are the step in Viruses replication in eukaryotic cell?
Definition

1. attachment and penetration by parent virion

2. uncoating of viral genome

3. Early viral mRNA synthesis

4.Early viral protein synthesis

5.Viral genome replication

6. Viral genome replication

7.Late viral mRNA synthesis

8. Late viral protein synthesis

9.Progeny assembly

10. Virion release

Term
What is the exception of Parvovirus?
Definition
does not produce Replicase-Polymerase
Term
What happens in early period in viral replication?
Definition
enzymes involved in synthesis of viral DNA and RNA, transcription and translation protein.
Term
What happens in late period in replication of virus?
Definition
to synthesis structural proteins: capsid, spike proteins-peplomeres, matrix proteins...
Term
What is receptor on human cells of HIV and rival protein associated with it?
Definition

CD4 & Chemokine receptors (Macrophage, TH)

 

gp120 envelope/gp41 protein

Term
What is receptor on human cells of Rabies and rival protein associated with it?
Definition

Nicotinic Acetylcholine receptor/gangliosides

 

Viral G protein

Term
What is receptor on human cells of Influenza and rival protein associated with it?
Definition

Sialoologosaccharades or sialoglycoprotien

 

HA (hemagglutinin)

Term
What is susceptibility of a host cell?
Definition

mean a host cell to a specific virus depends on the presence of receptors on the cell membrane-Host Cell Tropism

 

Term
What are 2 components of Host Cell Tropism?
Definition
Host Range species specificity vs organ/tissue specificity
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