Term
Diabetes mellitus is a group of chronic diseases when the body does not produce or respond to insulin thus affecting metabolism of what? |
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Definition
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Term
Type 1 diabetics are what? |
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Definition
insulin dependent -this is immune mediated or idiopathic |
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Term
What are the symptoms of DM type 1 at diagnosis? |
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Definition
lean polydipsia polyuria hyperglycemia electrolyte disturbances ketoacidosis length of onset |
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Term
Does it take a while for pts with DM1 to have symptoms? |
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Definition
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Term
What 6 factors contribute to the etiology of DM1? |
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Definition
genetic insulin deficiency islet cell destruction autoimmune dz external factors improvement prior to deterioration |
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Term
What factors accompany the occurrence of DM2? |
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Definition
obesity age genetics past medical history physical activity |
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Term
In DM2, there are no formation of what? What actually does contribute to glucose intolerance? |
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Definition
no formation of antibodies. antibody formation is not involved in glucose intolerance in DM2 -genetics and environmental factors actually do contribute to glucose intolerance. |
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Term
What are 3 possible defects in DM2? |
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Definition
Abnormal insulin secretion (or insulin resistance) Reduced glucose uptake Increased AM fasting glucose |
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Term
What is the most common type of diabetes mellitus? |
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Definition
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Term
What are the various categories of glucose intolerance? |
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Definition
other diseases/ steroid use malnutrition impaired glucose intolerance gestational diabetes (high incidence of fetal mortality) injury and stress of trauma severe trauma pancreatitis cystic fibrosis |
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Term
For the dx of DM to be made, what is the fasting glucose? what is normal? |
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Definition
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Term
What other tests are sued to diagnose DM? |
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Definition
Plasma glucose > 200 mg/dl with symptoms Oral glucose tolerance test |
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Term
What are the goals of DM management? |
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Definition
to prevent or delay complications weight control medical nutrition therapy glycolated hemoglobin tests blood glucose levels lipid levels |
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Term
What are some complications of DM? |
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Definition
vasciular renal GI retinopathy CVD |
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Term
One of the GI complications of DM2 is gastroparesis, explain what happens? |
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Definition
Gastroparesis develops bc the nerves are dying -so the diabetic will not empty their food out well -the thing you digest the quickest is carbs then protein then fat -diabetic products are high fat, so if a person with gastroparesis eats these high fat products they will have a lot of vomiting and diarrhea |
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Term
What is the hgb-A1C goal for a non-diabetic? for a diabetic? |
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Definition
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Term
With an A1C of 6, blood sugar is ~126. So, if blood sugar is in the 150 range what will A1C be? |
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Definition
like 7 for every 27 or 28 increase in the blood glucose level, the A1C will go up. |
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Term
The management of DM involves a consistent food plan that ha been individualized to lifestyle and calorie requirements via what 2 methods? |
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Definition
CHO counting Exchange system |
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Term
How does CHO counting work? |
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Definition
15 g CHO = 1 CHO choice -then determine total CHO per meal |
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Term
What foods have carbohdrates in them? |
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Definition
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Term
What is the diabetic diet now called? |
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Definition
consistent carbohydrate diet |
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Term
How are carbs and calories distributed to various pts? |
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Definition
almost everyone is given the same amt of calories, but are given carbs in a specific pattern |
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Term
What is the mgmt strategy for DM1? |
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Definition
consistent intake (should not vary more than a half hour from day to day) timing of meals insulin adjustments (like when planning on intaking a bunch of sugar) monitoring of BG levels multiple injections |
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Term
What is the mgmt strategy for DM2 pts? |
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Definition
*these strategies are more related to getting normal blood glucose levels, weight loss, triglyceride level goals -start off on diet alone, then meds, then injections. normal BG levels normal lipid levels weight loss/ maintenance exercise behavior modification fat intake medications |
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Term
What is the goal protein intake per day? |
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Definition
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Term
What should the fat intake be like? |
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Definition
limit saturated fat <30% of total calories increased MUFA |
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Term
Which is better for you: MUFAs or PUFAs? |
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Definition
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Term
Which is better for the DM pt: sweeteners or sugars? |
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Definition
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Term
PUFAs are ____ oil. MUFAs are ____ oil. |
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Definition
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Term
How should diabetic pts intake CHOs? |
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Definition
complex CHOs are better avoid simple sugars |
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Term
What is the goal fiber intake for diabetics? |
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Definition
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Term
Is sodium usually restricted in diabetics? |
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Definition
not usually unless they have a problem with edema and CHF |
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Term
Is there a need to supplement vitamins and minerals in diabetics? |
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Definition
no, but may be a good idea to supplement promium |
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Term
What are the 3 different types of insulin regimens? |
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Definition
conventional intensive insulin therapy (MDIs) continuous subQ insulin infusion (pump) |
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Term
The pump is usually used by DM1, if these pts are alert enough to manage their own pump does dietetics step in? |
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Definition
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Term
What is the normal response to oral DM agents? |
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Definition
initially have a good response then a secondary failure. |
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Term
What is the usual duration of oral DM meds? |
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Definition
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Term
What are the 7 classes of oral DM meds + insulin? these are all different in their modes of action. |
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Definition
Alpha-Glucosidase Inhibitors Amylin Analogs Incretin Mimetics Biguanides Meglitinides Sulfonyureas Thiazolidinediones Insulin |
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Term
What are the benefits of exercise in DM? |
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Definition
Weight control improved insulin sensitivity reduces CV risk factors |
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Term
There are potential problems when diabetics exercise, so what should they do to avoid problems? |
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Definition
proper BG monitoring insulin dose adjustment CHO loading -exercising more than 40-60 mins drains the glucose |
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Term
How can some DM2 pts completely cure their condition? |
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Definition
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Term
When a diabetic is CHO loading, what should they be loading with? |
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Definition
complex carbohydrates, not simple sugars |
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Term
What are some acute complications of DM? |
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Definition
Hyperosmolar Hyperglycemic Nonketotic Syndrome Hyperglycemia Hypoglycemia SOMOGYI Effect DAWN phenomenon |
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Term
What are some long-term complications of DM? |
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Definition
MACROVASCULAR -Lipid abnormalities -Hypertension
MICROVASCULAR -retinopathy -nephropathy -neuropathy
Brittle DM- Dawn phenomenon in young children |
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Term
Why is renal failure one of the worst complications of DM? |
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Definition
it is the worst, most restrictive diet to follow. |
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Term
What is the Somogyi effect? |
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Definition
when have a reactive hyperglycemia then blood sugar drops. -then given something for the hypoglycemia which makes them hyperglycemic |
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Term
What is the Dawn Phenomenon? |
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Definition
more with DM2 when sugars are really high in the liver -liver releases glycogen while fasting, so can fix this with 1-2 carbs before going to bed at night |
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Term
What are the steps involved with the lifetime mgmt of diabetes? |
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Definition
assessment goal establishment implementation evaluation documentation |
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Term
How is a patient managed who has DM prior to pregnancy? |
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Definition
good control of sugars have hypoglycemia risks and insulin requirements. |
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Term
_% of pregnant people get gestational DM, how should this be managed? |
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Definition
7% diagnosis diet exercise self-monitoring |
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Term
What is the goal for growth and development in children with DM? |
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Definition
3 meals with 2-3 snacks constant re-evaluation as they grow
these kids can pretty much eat whatever bc their parent monitor their pump and they are constantly re-evaluated |
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Term
Why is the incidence of DM2 increasing in children? |
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Definition
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Term
With DM2 in children what needs to be done? |
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Definition
lifestyle changes assess HbA1C levels may need metformin OHA |
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Term
What are some contributing factors of DM in the elderly? |
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Definition
Decreased insulin production VS increased insulin resistance
Medications
Physical activity
Genetics
Other illnesses |
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Term
What are the symptoms of hypoglycemia? |
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Definition
3 features of Whipple's Triad. (1) neuromuscular signs with fasting or exercise (2) low blood glucose levels associated with clinical signs (3) reversal of clinical signs with the administration of glucose. |
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Term
What is the tx of hypoglycemia? |
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Definition
administration of some sort of carbohydrate -give them 6-8 small feedings a day encourage -encourage a higher protein diet to prevent low drops of sugars |
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Term
When do people normally go hypoglycemic? |
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Definition
3-4 hrs after eating... may even have dumping syndrome where after they eat they have diarrhea |
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Term
Do we know the cause to hypoglycemia? |
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Definition
no. don't even know if people are true hypoglycemics. |
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Term
What is the mouth and esophagus used for? |
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Definition
mastication and swallowing secretions (salivary and esophageal) |
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Term
Once you start to swallow, can you sstop? |
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Definition
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Term
What is the function of mucous secretions in the esophagus? |
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Definition
to make it slick, does not have a protective mechanism |
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Term
The small intestine is the work horse of the GI tract, what does it do? |
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Definition
Digestion & absorption Protein breakdown CHO breakdown Fat breakdown Digestive juices Hormones Vitamins, Minerals, & drugs |
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Term
What does the liver contribute to the GI tract? |
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Definition
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Term
What is the primary purpose of the large intestine? |
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Definition
to absorb water -absorbs some minerals as well |
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Term
What is the bacterial action of the large intestine? |
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Definition
metabolizes fatty acids into short chain fatty acids |
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Term
Where does dietary fiber do all of it's job? |
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Definition
in the large intestine, up until this point it is undugested |
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Term
Do some secretions protect the large intestine? |
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Definition
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Term
There are many reasons for tissue inflammation to be in the mouth, name some reasons |
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Definition
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Term
What are the four inflammatory diseases of the mouth? |
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Definition
gingivitis stomatitis glossitis cheilosis |
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Term
What can happen if gingivitis gets severe enough? |
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Definition
ulcerations can occur and abx are needed to clear up the infection |
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Term
What is stomatitis caused by? |
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Definition
chemotherapeutic agents B vitamin deficiencies
with this, it hurts to eat anything |
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Term
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Definition
Is the result of a B vitamin deficiency -have a red swollen tongue -with full blown glossitis, it looks like they don't have taste buds, tongue looks really smooth |
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Term
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Definition
splitting in the corners of the mouth -seen a lot in college age kids bc they aren't eating right |
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Term
What is the dietary tx with mouth disorders? |
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Definition
start out with softer foods and non-acidic things -avoid temperature extremes -chloriseptic spray is good before mealtime for numbing -none of this will get any better without good nutrition |
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Term
Can you give someone with any of these mouth diseases a feeding tube? |
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Definition
no -if really severe may give them a peg tube. |
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Term
Who has issues with poor dentition? |
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Definition
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Term
What is a reason for dentures not fitting anymore? |
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Definition
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Term
What is done for pts with too little salivary production? |
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Definition
given artificial saliva -saliva is important for adequate mastication and formation of a good food bolus |
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Term
Can develop dysphagia after a stroke, head and neck surgery or long term feeding tube use... who do these pt then need to see? |
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Definition
a speech therapist -Susan doesn't like speech therapists |
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Term
What is the easiest thing for people with dysphagia to swallow? |
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Definition
pudding and thicker liquids (Pureed) -with water it goes down to quickly and aspration pneumonia can occure -so be careful about ordering a clear liquid diet |
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Term
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Definition
A DISEASE INVOLVING THE MOTILITY OF THE ESOPHAGUS. AFFECTS THE MUSCLE MOVING THE FOOD DOWN THE ESOPHAGUS |
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Term
What are the symptoms of achalasia? |
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Definition
regurg, chest pain, coughing, problems swallowing |
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Term
What does surgery for the mgmt of achalasia entail? |
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Definition
dilitation -reduce pressure of the lower esophageal sphincter -botox and meds |
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Term
What is the dietary mgmt of achalasia? |
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Definition
fatty foods alcohol and peppermint/spearmeint lower LES pressure smaller more frequent meals |
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Term
What are the symptoms of GERD? |
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Definition
Heartburn dysphasia nausea after eating |
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Term
With GERD, what kinds of foods should be avoided? |
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Definition
foods that decrease LES pressure- fat, alcohol, peppermint -coffee and tea increase acid |
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Term
What meds are sued to tx GERD? |
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Definition
lifestyle changes PPIs and H2 blockers no aspirin or ibuprofen -really don't use antacids anymore |
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Term
With GERD, want to _______ the sphincter. With achalasia, want to ______ the sphincter. |
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Definition
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Term
What are 2 side effects of chronic esophagitis? |
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Definition
asthma barrett's esophagus
both of these are closely related to esophageal cancer |
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Term
Chronic esophagitis has the same tx as what? |
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Definition
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Term
What is the mgmt of hiatal hernia? |
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Definition
antacids weight reduction don't eat before you lie down flat |
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Term
How do you get a feeding tube past a hiatal hernia? |
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Definition
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Term
How do you manage cancer of the esophagus? |
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Definition
dietary changes -then only take fluids and then take them to surgery |
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Term
What surgery is done on cancer of the esophagus? |
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Definition
esophegectomy -body heals the tract pretty quickly -bc these pts are generally malnourished |
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Term
With a pt with N/V, need to dig deeper into the cause, what could this cause be? |
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Definition
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Term
What are the causes of peptic ulcer dz? |
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Definition
aspirin and NSAID use stress ulceration H. pylori infxn
NSAID use is the most common cause. |
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Term
What is the therapy of PUD? |
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Definition
acid suppression through use of PPIs and H2 blockers
start them on 4 blands: 1-4 limit snacking: the more times you eat, the more you're going to stimulate the acid production limit seasonings: red pepper, really spicy things -maybe limit chocolate |
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Term
PUD is a disease of what organ? |
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Definition
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Term
What are the 3 gastric surgeries? |
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Definition
vagotomy partial/complete gastrectomy gastric bypass |
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Term
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Definition
reduces acid secretion slows gastric emptying -may result in dumping syndrome
usually done for gastric cancer |
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Term
With a parital/complete gastrectomy, what would surgeons rather place? |
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Definition
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Term
What are the 3 types of gastric bypass surgery? |
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Definition
Roux-en-Y -standard for weight loss (50-65%) -biliopancreatic diversion (60-80% wt loss) Billroth I -gastroduodenostomy Billroth II -gastrojejunostomy |
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Term
What can Billroth I and II result in? |
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Definition
malabsorption, are only done when absolutely necessary |
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Term
What is dumping syndrome the physiologic response to? |
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Definition
the presence of larger amts of food than normal into the small intestine |
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Term
What procedures can cause dumping syndrome? |
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Definition
total or subtotal gastrectomy (no stomach, no holding cell for food before the mall intestine) pyloroplasty fundoplication |
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Term
What are the symptoms of dumping syndrome? |
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Definition
fullness and nausea fluid shifts causing flushing, tachycardia, sweating, cramping, diarrhea and hypoglycemia |
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Term
What is the post-gastrectomy diet to avoid dumping syndrome? |
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Definition
limits simple carbs (sugar) and complex carbs (bread, fruit) -beverages are given 30-60 mins after they eat real food. |
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Term
In the lower GI tract, what are 3 ways in which malabsorption can occur? |
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Definition
mechanical: missing part of GI tract (adhesions, surgical removal, obstructions) -<270 M of small bowel is short gut
chemical: inadequate production of amylase or lipase, whipple procedure
solubilization: don't make enough bile salts can have fat malabsorption |
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Term
What 2 things can cause diarrhea in the lower GI tract? |
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Definition
diet: lack of appropriate fiber lactose intolerance: AAs, asians, NAs and age |
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Term
What kind of diet do people with celiac sprue need to adopt? |
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Definition
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Term
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Definition
Permanent intestinal intolerance to dietary wheat gluten & related proteins that produces mucosal lesions in genetically susceptible individuals |
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Term
What are some general causes of celiac dz? |
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Definition
genetics immune system environment (bacterial or viral) |
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Term
What are the symptoms of celiac dz? |
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Definition
diarrhea (bulky, loos and watery) weight loss (failure to thrive) abdominal swelling and bloating with excess gas and abd pain |
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Term
How is celiac dz diagnosed? |
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Definition
antibody detection intestinal bx |
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Term
What is the tx of celiac dz? |
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Definition
gluten free diet: eliminate foods containing wheat, barley, rye and oats |
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Term
What needs to be supplemented in people with celiac dz? |
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Definition
calcium zinc vitamin D Mg Vitamin B12 |
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Term
Crohn's and UC are inflammatory diseases of what? |
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Definition
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Term
Where does Crohn's occur? Is it genetically associated? What do the lesions become? Are fistulas and strictures common? At what age? |
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Definition
any part of the GI tract yes chronic yes ( any age |
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Term
What is UC confined to? Are the exacerbations more acute or chronic? What does it only affect? |
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Definition
colon and rectum acute mucosa of the GI tract |
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Term
In crohn's, what makes the pts nonresponsive to tx? what do they then need? |
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Definition
fistula development multiple resections |
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Term
What must UC be monitored for? |
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Definition
progression to cancer -usually ends in colostomies or colectomies |
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Term
What is the drug therapy for IBD: Crohn's and UC? |
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Definition
Steroids and anti-inflammatories -treated first with drugs, then to surgery and different types of resections |
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Term
What is the nutritional therapy of IBD? |
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Definition
TPN is no longer an accepted practice, so is EN -every pt is different, and pt knows what foods bother them
high calorie, high protein diet with inflammation: on a low residue diet (no milk or fiber) when inflammation leaves, are put on a high fiber diet |
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Term
What are the nutritional risks and deficiencies present in IBD? |
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Definition
Iron Folate Nicotenic acid Vitamin D Vitamin K Calcium Magnesium Zinc |
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Term
When UC pts are really inflamed, what do they have? |
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Definition
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Term
Crohn's have lesions everywhere in GI tract, where are they most obviously seen? |
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Definition
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Term
What is short bowel syndrome defined as? |
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Definition
jejunal + ileal bowel length of 100-200 cm |
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Term
What are the clinical symptoms of short bowel syndrome? |
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Definition
fat malabsorption diarrhea |
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Term
What is the nutritional mgmt of short bowel syndrome? |
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Definition
TPN 3 adaptive stages dietary strategies
many times are allowed to eat for the satisfaction of eating. |
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Term
With short bowel syndrome you have malabsorption of electrolytes, vitamins and trace elements of what 7 things? |
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Definition
iron calcium magnesium fat soluble vitamins zinc B12 Folate |
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Term
What are the causes of diverticular dz? |
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Definition
low fiber diet constipation |
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Term
What are the complications of diverticular dz? |
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Definition
abscesses fistula perforation peritonitis |
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Term
How much fiber should someone with diverticulosis intake each day? what else should they intake more of? |
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Definition
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Term
With diverticulitis, what is the mgmt? |
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Definition
clear liquids low residue diet surgery |
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Term
When does diverticular dz go from benign to not benign? |
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Definition
when the diverticuli start perforating bc all the e. coli and deadly junk on the inside of the GI tract gets into the sterile peritoneum--> can get into other organs and become deadly |
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Term
______________ is just treated wih a high fiber diet while ______________ might progress to needing surgery. |
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Definition
Diverticulosis diverticulitis |
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Term
What is irritable bowel syndrome? |
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Definition
a functional intestinal disorder due to muscle spasms in response to food, gas and stress symptoms include abd pain, constipation, diarrhea and bloating |
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Term
What id the nutritional tx of IBS? |
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Definition
individualized: eat slowly, high fiber, increased water, frequent small meals, decreased fat intake
deal with the stress! |
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Term
What are foods to avoid in a pt with diarrhea? |
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Definition
EtOH caffeine nicotine gas producing foods dairy spicy food high fat foods sorbitol (in meds) |
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Term
What do you need to ask people who have diarrhea? |
|
Definition
what does it look like?
if greasy and floating, probably have fat malabsorption |
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Term
What foods should be increased with constipation? |
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Definition
fresh fruits and vegetables wheat bran whole grain break and cereals beans increase slowly in diet increased water consumption
avoid laxatives! unless are chronically on laxatives (but think about weening them off laxatives) |
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Term
How should fiber be increased in a diet? |
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Definition
gradually, if increase too quickly will get bloating, gas and diarrhea. |
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Term
What are the symptoms of viral hepatitis? |
|
Definition
anorexia weight loss jaundice |
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Term
How is viral hepatitis treated? |
|
Definition
rest adequate fluid adequate protein and high CHO moderate fat (limit fat bc will probably have fat malabsorption) supplementation of water and fat soluble vitamins (bc of fat malabsorption) calories of 1.5 times basal needs. |
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Term
What is one of the most common types of liver dz? |
|
Definition
alcoholic liver dz... usually results in poor nutrition she also said hepatic steatosis (associated with obesity) |
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Term
What do pts with alcoholic liver dz need lots of? |
|
Definition
calories... and 60-80 g/day of dry protein |
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Term
What is the progression of alcoholic liver dz? |
|
Definition
fatty liver --> liver fibrosis --> cirrhosis |
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Term
What is the dietary tx of hepatic steatosis? |
|
Definition
weight loss avoid alcohol mediterranean diet (anti-inflammatory)
primarily treated with diet |
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Term
What is the nutritional therapy of someone treated with cirrhosis? |
|
Definition
Protein -no flare up: normal amt of protein -with flare-up: 150% of the protein they need to maintain muscle mass
Calories -no flare up: 25% more calories -with flare up: 50% more calories
CHO
Fat -these people have malabsorption of fat.. given MCT (medium chain triglyceride) absorbed directly into lymph in order to get calories from fat
Sodium
Vit/Min Alcohol -NONE! Fluid |
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Term
hepatic encephalopathy can either be acute or chronic, how is it treated? |
|
Definition
Protein amount & sources -start low, and increase to what they need -adjusted by whether or not encephalopathy is progressing Calories Fluids Vit/Min Lactulose -given to lower ammonia levels by making them malabsorb and have diarrhea |
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Term
Pts with hepatic failure will usually also go into what? |
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Definition
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Term
What are the 2 gall bladder diseases and their tx? |
|
Definition
cholecystitis and cholelithiasis
surgical -after 2-3 attacks, will take their gall bladder out nutritional (limited fat and calories) |
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Term
How are pts with acute pancreatitis fed? |
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Definition
enterally: feeding tube into ligament of trietz (transpyloric) -usually will use products high in MCT oil -this is new, they used to just give the gut a rest |
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Term
Chronic panreatitis is more common, what type of pt can move to this? |
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Definition
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|
Term
Chronic pancreatitis is painful, and pts can become what? |
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Definition
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|
Term
Feeding chronic pancreatitis pts is hard, what may have to be used? |
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Definition
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|
Term
If chronic pancreatitis pts do start eating again, what do they have to have? |
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Definition
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|
Term
What is more common a problem, diarrhea or constipation? |
|
Definition
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|
Term
What is the most common GI dz? |
|
Definition
diverticular dz -main cause is constipation and low fiber diet. |
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|
Term
What is the nutritional therapy required for glomerulonephritis? |
|
Definition
salt restriction disease progression: protein, CHO, electrolytes, water |
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Term
There are multiple causes of nephrotic syndrome, what are some symptoms? |
|
Definition
proteinuria poor appetites weight loss |
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|
Term
What is the nutritional therapy for nephrotic syndrome? |
|
Definition
protein and calories! sodium restriction |
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|
Term
In acute renal failure, dialysis is required... what are the 2 types of dialysis? |
|
Definition
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|
Term
What is the nutritional therapy of acute renal failure? |
|
Definition
Protein: 1.0-2.0 grams/kg of actual/ideal weight
Energy: Begin at < 25 kcal/kg when critically ill then liberalize as needed
Electrolytes:Degree of restriction depends upon treatment |
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|
Term
What is the GFR for various stages of chronic kidney dz? |
|
Definition
Stage 1: proteinuria: >90 Stage 2: mild damage: 60-89 Stage 3: moderate: 30-59 Stage 4: 15-29 Stage 5: <15 |
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|
Term
What is the nutritional therapy of chronic renal dz? |
|
Definition
Protein Calories Fluid Sodium Potassium Phosphorus & Calcium Vitamins / Minerals |
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|
Term
What is the tx of chronic renal dz? |
|
Definition
dialysis -hemodialysis -peritoneal dialysis -ultrafiltration diet fluid restriction |
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|
Term
What are you worried about with renal transplants? |
|
Definition
immunosuppression rejection episodes |
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|
Term
What nutritional therapy is required with a renal transplant? |
|
Definition
Protein CHO Fat Calories Sodium |
|
|
Term
What are the 4 types of kidney stones? |
|
Definition
calcium struvite uric acid cysteine |
|
|
Term
What is encouraged with cystitis? |
|
Definition
adequate fluid intake cranberry juice- to coat the lining of the bladder making bacterial colonization more difficult |
|
|
Term
How does nutrition play a role in cancer development? |
|
Definition
mutations chemical radiation viruses epidemiological factors: diet, race, occupation |
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Term
Energy balance and exercise prevents what type of cancer? |
|
Definition
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|
Term
Fat prevents what type of cancer? |
|
Definition
|
|
Term
Protein prevents what type of cancer? |
|
Definition
|
|
Term
Fiber prevents what type of cancer? |
|
Definition
|
|
Term
How do fruits and vegetables affect cancer? |
|
Definition
contain antioxidants, phytochemicals |
|
|
Term
CHO has an effect on what type of cancer? |
|
Definition
|
|
Term
What else is linked to cancer? |
|
Definition
alcohol coffee and tea artificial sweeteners nitrates |
|
|
Term
Cancer therapy includes what 5 things? |
|
Definition
Surgery Radiotherapy Chemotherapy Immunotherapy Marrow Transplantation |
|
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Term
|
Definition
alteration of metabolism resulting in subsequent death of the host |
|
|
Term
What 5 factors lead to unintentional weight loss in cancer? |
|
Definition
decreased nutrient intake from GI fxn related to direct tumor or adverse effects from treatment
obstruction/perforation of GI tract
Intestinal secretory abns
Anorexia (depression, food aversion, early satiety)
Nutritional consequences of tx -chemo -radiation -surgery |
|
|
Term
What are some metabolic changes induced by cancer? |
|
Definition
protein fat glucose energy expenditure role of cytokines |
|
|
Term
What are some nutritional parameters of cancer? |
|
Definition
weight changes body composition lab values nutrient intakes |
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|
Term
What are some feeding modalities with cancer? |
|
Definition
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|
Term
What nutritional requirements are you worried about with cancer? |
|
Definition
calories protein fluid vitamins and minerals |
|
|
Term
Besides feedings, what are some other therapies of nutrition in cancer? |
|
Definition
Metabolic Therapy Macrobiotic Diet Megavitamin therapy Herbal therapy “Cleansing therapies” |
|
|
Term
What is the ideal appetite stimulant for cancer pts? |
|
Definition
sustained positive effects on appetite association bw agent use and repletion or maintenance of body cell mass minimal adverse effects no negative effects on tx positive effects on QoL |
|
|
Term
What are three types of appetite stimulants? |
|
Definition
glucocorticoids -short-lived effects -adverse effects
cannabinoids -increased appetite, decreased nausea
megestrol -positive effect on appetite -minimal increase in weight -better long-term results. |
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|
Term
Have fish oils (antcytokine agents) proved effective in cancer pts? |
|
Definition
no -no differences in appetite or weight change -no changes of measures of fxn or well-being |
|
|
Term
Prevention with nutrition remains controversial, what foods are up for debate? |
|
Definition
soy (breast and prostate cancer)
fruits and vegetables (GI and lung cancers)
tomatoes garlic vitamin D
alcohol- increases cancer risks
wine- contains compounds in grape skins that can help fight certain cancers
selenium- boosts body's antioxidant activity |
|
|
Term
|
Definition
safe and effective mode of nutritional support when delivered by strict protocols |
|
|
Term
What are the indications for parenteral nutrition? |
|
Definition
non-fxnal GI tract
bowel rest
severe malnutrition when pt will be unable to eat for more than 5 days |
|
|
Term
What are the contraindications for parenteral nutrition? |
|
Definition
tx required for less than 5 days
fxnal GI tract
inability to obtain venous access
prognosis |
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|
Term
When to initiate PN: guidelines: ASPEN/CCM vs ESPEN |
|
Definition
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|
Term
Summarize the ASPEN/CCM guidelines. |
|
Definition
If EN is not available, and the iCU pt is previously normally nourished, then PN can be started after first 7 days of hospitalization.
-if evidence of protein-calorie malnutrition on admission and EN is not feasible, then PN can be started as soon as adequate resuscitation is performed |
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|
Term
Under ASPEN/CCM guidelines, if the pt is expected to undergo major upper GI surgery and EN is not feasible, when should PN be provided? |
|
Definition
-if pt is malnourished, PN should be initiated 5-7 days preoperatively and into the post-op period
-PN should not be INITIATED immediately after surgery, but should be delayed 5-7 days post-op if EN is not feasible
-PN should only be initiated only if the duration of therapy is anticipated to be >7 days, anything less than that will have no effect and could cause harm to the pt. |
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|
Term
Late initiation of parenteral nutrition is associated with a ______ recovery and ______ complications as compared with early initiation. |
|
Definition
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|
Term
ESPEN says PN should only be used when? |
|
Definition
when absolutely necessary |
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|
Term
What are the physiological limitations of PN? |
|
Definition
atrophy of small bowel mucosa decreased adaptive capacity bacterial translocation increased incidence of sepsis |
|
|
Term
What are the types of access for PN? |
|
Definition
Central Venous Access: -subclavian vein preferred site (risk of PTX) -internal jugular (more uncomfortable) -groin: greatest risk of infection -PICC
Implanted central venous catheters: -for prolonged TPN access -inserted operatively -implanted in a subQ tunnel -most common types: Hickman, Port-a-cath, Groshong |
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|
Term
What are some complications of PN? |
|
Definition
Pneumothorax Artery injury Catheter malposition Infection: Local & systemic Air embolism; catheter embolism Catheter occlusion Venous thrombosis |
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|
Term
When prescribing for PN, what do you need to assess for? |
|
Definition
nutritional risk nutritional needs: protein, fat, CHO, fluids, electrolytes, vitamins, minerals and trace elements. |
|
|
Term
When delivering nutrients to the body's disposal system, what do you NOT want to overload? |
|
Definition
the body's disposal system. |
|
|
Term
When delivering protein, what do you need to consider? |
|
Definition
|
|
Term
When delivering CHO, what do you need to consider? |
|
Definition
200g required for nitrogen utilization -oxidative limit of 7g/kg/day |
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|
Term
When delivering fat, what do you need to consider? |
|
Definition
hyperlipidemia -limit to <30% total calories |
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|
Term
When delivering fluids, what do you need to consider? |
|
Definition
evaluate CHF pulmonary edema renal insufficiency ARDS |
|
|
Term
what is the composition of proteins when prescribing PN? |
|
Definition
Synthetic crystalline amino acids Solutions may lack certain AA due to instability Solutions contain varying amounts of electrolytes Concentrations depend upon final volumes Hypertonic solutions |
|
|
Term
What is the composition of dextrose when prescribing PN? |
|
Definition
5%-70% solution dextrose in water 3.4 kcal per gram Most abundant component in TPN Component with the greatest effect on the hypertonicity of the solution |
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|
Term
What is the composition of lipids when prescribing for PN? |
|
Definition
Should have < 30% as total calories Sources are soy or safflower oils Linoleic acids are precursors to prostaglandins (immunosuppressive, vaso-constrictive)
Structured and fish oil parenteral lipids not approved for use in this country |
|
|
Term
|
Definition
Total Nutrient Admixture "three-in-one" solutions |
|
|
Term
|
Definition
amino acids and dextrose with lipids piggybacked into the solution |
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|
Term
What vitamins and trace elements is PN composed of? |
|
Definition
Vitamin A Vitamin D Vitamin E Ascorbic acid Folate Niacin Thiamine Riboflavin B 6 B 12 Pantothenic acid Biotin Vitamin K
Trace Elements: Zinc Copper Chromium Manganese
Selenium |
|
|
Term
What vitamins and trace elements is PN composed of? |
|
Definition
Vitamin A Vitamin D Vitamin E Ascorbic acid Folate Niacin Thiamine Riboflavin B 6 B 12 Pantothenic acid Biotin Vitamin K
Trace Elements: Zinc Copper Chromium Manganese
Selenium |
|
|
Term
What can be added into PN? |
|
Definition
Insulin H2 Blockers Heparin Additional vitamins and minerals |
|
|
Term
Initially, how is PN nutrition administered? then what occurs after tolerance is established? |
|
Definition
over 24 hours -consider cyclic TPN (in anticipation of home TPN) --12-26 hr cycles --usually night infusions |
|
|
Term
What GI complications can occur with PN? |
|
Definition
Fatty liver Cholestasis GI atrophy |
|
|
Term
What metabolic complications can occur with PN? |
|
Definition
Electrolyte imbalances (Na and K) Glucose intolerance Hypertriglyceridemia Dehydration Fluid overload Prerenal azotemia Mineral imbalances (Ca, Mg, P) Overfeeding (Hypercapnia) Essential fatty acid deficiency
Mineral imbalances Calcium Magnesium Phosphorus Overfeeding Hypercapnia Essential fatty acid deficiency |
|
|
Term
How should these metabolic complication be monitored? |
|
Definition
daily chemistries until electrolytes are stable fingerstick blood glucose levels 4-6 times daily fluid balance live fxn tests weekly WBC and temperatures daily |
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|
Term
How can PN's nutritional values be monitored? |
|
Definition
lab data: prealbumin, total lymphocyte count, serum albumin of limited value
daily weights
nitrogen balance, if available |
|
|
Term
Enteral Nutrition... if the gut works and can be used safely, use it! |
|
Definition
|
|
Term
What are the physiologic benefits of enteral nutrition? |
|
Definition
nutrients are metabolize and utilized more effectively
can be used in most cases of gastric and colonic dysfxn, bc small bowel function is maintained. |
|
|
Term
What are the immunologic benefits of enteral nutrition? |
|
Definition
maintains gut integrity prevents bacterial translocation from the gut (systemic sepsis and increased risk of multiple organ failure) |
|
|
Term
What are the biochemical benefits of enteral nutrition? |
|
Definition
many formulas contain glutamine (which is the preferred gut fuel during metabolism)
many formulas contain fiber that stimulate mucosal growth in the GI tract |
|
|
Term
What are the metabolic benefits of enteral nutrition? |
|
Definition
decreased catabolic response after injury or stress if fed through the GI tract
stimulates production of hormones for gut mucosal growth |
|
|
Term
What are the safety benefits of enteral nutrition? |
|
Definition
avoids complications associated with line placement |
|
|
Term
What are the cost benefits of enteral nutrition? |
|
Definition
|
|
Term
what are the 2 contraindications of enteral nutrition? |
|
Definition
malfunction of the GI tract end-stage illness where harm exceeds benefit |
|
|
Term
What are some examples of malfunctions of the GI tract that would result in the contraindication to enteral nutrition? |
|
Definition
short bowel syndrome with inadequate length of jejunum and ileum present
mechanical obstruction of the GI tract -sometimes can feed below it, but if too low may need to do IV nutrition
prolonged ileus
severe GI hemorrhage
Intractable vomitting
high output fistula (may be able to feed below it if it is high enough)
pancreatic pseudocyst |
|
|
Term
Lately, does Susan do enteral feeding for anyone with a pancreatic issue? |
|
Definition
|
|
Term
If are receiving enteral feeding for <4-6 wks, what placement should be used? for >4-6 wks? |
|
Definition
nasoenteric placement surgical placement |
|
|
Term
What are usual placements for the end of an EN tube? |
|
Definition
|
|
Term
What does PEG stand for, and what kind of feeding is it used for? |
|
Definition
Percutaneous Endoscopic Gastrotomy Enteral feeding |
|
|
Term
___________ are easy to place and are pretty short. |
|
Definition
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|
Term
What are the placement issues with a nasoduodenal tube? |
|
Definition
blind placement fluoroscopic placement |
|
|
Term
Which feeding tubes have to be surgically placed? |
|
Definition
Percutaneous Endoscopic Gastrostomy Button Gastrostomy (peds) Jejunostomy |
|
|
Term
Where are you usually trying to get the feeding tube to? |
|
Definition
|
|
Term
What 5 things should be kept in mind when prescribing enteral nutrition? |
|
Definition
Meeting nutrient requirements GI tract function Past Medical History Disease state Constraints on nutrient delivery |
|
|
Term
What are the formula types and composition? |
|
Definition
Polymeric Defined formula Disease- Specific Modular |
|
|
Term
What composes the polymeric enteral formula? |
|
Definition
-complex source of CHOs, protein and fat -requires normal digestion and absorption -most are lactose free -available in a calorically dense form (1.5-2kcal/cc) |
|
|
Term
What composes the defined formula? |
|
Definition
protein is hydrolyzed to peptides or aas
% of fat may be as MCT or as fish oils
minimal digestion required
may have a high osmolarity
available in a calorically dense form |
|
|
Term
With the disease specific enteral formula, what diseases does it include? |
|
Definition
renal failure liver failure pulmonary dz malabsorption/GI dz diabetes sever trauma/ injury |
|
|
Term
What is in the renal failure specific formula? |
|
Definition
CRT- continuous renal therapy -is a dialysis -gradually increase protein -give them whatever they need, bc they are just going to filter it out |
|
|
Term
Why are liver failure specific formulas the last resort? |
|
Definition
|
|
Term
With pulmonary dz specific formulas, which will you probably be in more contact with? |
|
Definition
ARDS -there is some controversy around pulmonary specific formulas |
|
|
Term
What is in the diabetic specific formula? |
|
Definition
high fat low CHO moderate protein "Glucerna", keep in mind gastroparesis problems though -worried about vomiting and aspiration with tube fed pts. |
|
|
Term
Is it good to put a critically ill pt on a high fat diet? |
|
Definition
No, maybe wait til they are out of the ICU |
|
|
Term
What is the enteral formula for a pt with severe trauma and injury? |
|
Definition
very specific: high protein, extra arginine, zinc and vitamin A for wound healing
-these formulas are pricy, and pts are not sent out of the hospital while on them |
|
|
Term
What is the modular formula composed of? |
|
Definition
single nutrients -combined to make a formula customized to each pt. -may be added to oral supplements or to enteral feedings -added to enhance healing/recovery |
|
|
Term
True or False: Enteral feedings should not be started until the GI tract is functional as identified by bowel sounds, bowel movements or “low” gastric residual volumes |
|
Definition
|
|
Term
True or False: Nothing can be started until hear bowel sounds, pass gas or see stool. |
|
Definition
|
|
Term
Summarize the Canadian Guidelines. |
|
Definition
EN preferred over PN EN: 24-48 hrs after admission to the ICU Does not address the presence or absence of bowel sounds
Initiate a feeding protocol that includes: -prokinetics -a higher GRV of 250 mL -postpyloric feeding tubes |
|
|
Term
When including a higher GRV of 250 mL what should be started with signs of intolerance? |
|
Definition
|
|
Term
When are posrpyloric feeding tubes recommended? |
|
Definition
routinely in critical care
for selected pts having persistent elevated GRVs or those at risk for aspiration and pneumonia |
|
|
Term
When are post pyloric feeding tubes recommended? |
|
Definition
routinely in critical care
for selected pts having persistent elevated GRVs or those at risk for aspiration and pneumonia |
|
|
Term
When may EN be started after adequate fluid resuscitation? |
|
Definition
24-48 hrs following injury or admission to the critical care unit |
|
|
Term
When may EN be started after adequate fluid resuscitation? |
|
Definition
24-48 hrs following injury or admission to the critical care unit |
|
|
Term
How does the American Dietetic Association stand on evaluating GRVs? |
|
Definition
Monitoring GRVs is an option to assess EN tolerance -hold EN when GRV>250 mL documented on 2 consecutive occasions -use promotility agents if pt has gastroparesis or persistently elevated GRVs -EN infused into the stomach is acceptable for most pts; small bowel feeding preferred with signs of intolerance
DOES NOT address presence of bowel sounds/movements
So: GRV recs: consensus/imperative promotility agents: strong/ conditional small bowel FT: fair/ conditional |
|
|
Term
read all the other guidelines in the enteral ppt. |
|
Definition
|
|
Term
True or false: tap water can be used safely to flush feeding tubes and to dilute meds to be given per feeding tube. |
|
Definition
false -use of sterile water is preferred for safety -meds should be given mixed in sterile water through feeding tubes |
|
|
Term
How should medications be given through feeding tubes? |
|
Definition
|
|