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Nutrition: Chapter 15
Trace minerals
72
Biology
Undergraduate 2
03/15/2010

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Cards

Term
Iron molecules
Definition

Heme iron (found in animal sources only)

Non-heme iron (both animal and plant sources)

Term
Factors that increase non-heme Fe absorption
Definition

Vitamin C

Citric Acid

Lactic Acid

Heme iron

Term
Decrease non-heme iron absorption
Definition

Fiber

Phytates

Tannins

Oxalates

Term
Fe food sources
Definition

FOOD SOURCES:

meat

seafood

enriched baked goods

Term

Fe

RDA

Definition

women* = 18 mg/day

men = 8 mg/day

 

drops to 8 mg/day after menopause

 

 

Term

Fe

Average intake

Definition
12-17 mg/day
Term

Fe

Upper limit

Definition

45 mg/day

causes hemachromatosis

Term
Proteins that help body absorb Fe
Definition

Ferritin

Transferrin

Term
Two ionic states of Fe
Definition

Ferrous iron (Fe2+)

Ferric Iron (Fe3+)

Term
Factors that increase Fe absorption
Definition

high demand for RBC's

low body stores of Fe

heme iron in food

MPF

Vitamin C intake

Gastric acidity

Term
Factors that decrease Fe absorption
Definition

low need for iron

phytic acid in whole grains and legumes

oxalic acid in leafy vegetables

polyphenols in tea, coffee, wine and oregano

reduced gastric acidity

excessive intake of other minerals (Zn, Mn, Ca)

Term
Functions of Fe
Definition

FUNCTIONS:

Hemoglobin

Myeglobin

iron-containing enzymes

Term
Storage of Fe
Definition

Ferritin

hemosiderin

Term
Transport of Fe
Definition

Transferrin

Ferroportin

Term
Fe deficiency
Definition
Iron deficiency anemia
Term
At risk for Fe deficiency
Definition

Premies

Kids

Females of childbearing age

vegetarians

Term
Fe toxicity
Definition

hemachromatosis

caused by genetic disorder that enhances absorption

Term
Consequences of hemachromatosis
Definition

apathy

lethargy

fatigue

darkened skin

Term
Symptoms of Early Fe deficiency
Definition
No apparent symptoms
Term
Symptoms of moderate Fe deficiency
Definition

Decreased work/exercise capacity

Decreased immune function

Term
Symptoms of severe Fe deficiency
Definition

Increased fatigue

Increased infection

poor work/exercise performance

decreased growth and cognitive development in kids

increased mortality

Term
Food sources of Zinc (Zn)
Definition

FOOD SOURCES:

protein rich meat

seafood

vegetables depending on soil

Term

Zn

RDA

Definition

men = 11mg/day

women = 8 mg/day

Term

Zn

Daily Value

Definition
15 mg/day
Term

Zn

Upper Limit

Definition
40  mg/day
Term
Absorption of Zinc
Definition
Albumin carries zinc in blood
Term
Transport of Zinc
Definition
Via transferrin
Term
Factors that increase Zinc absorption
Definition

Low to moderate zinc intake

Zinc deficiency

animal protein intake

increased need for zinc

Term
Factors that decrease Zn absorption
Definition

phytic acid and fiber

excessive zinc intake

high non-heme iron intake

good zinc status

 

Term
Functions of Zinc
Definition

FUNCTIONS:

required by 300 different enzymes 

Term
Zinc deficiency
Definition

Overt among impoverished

Marginal in US

Term
Trace Minerals
Definition

Iron

Zinc

Copper

Manganese

Iodine

Selenium

Chromium

Fluoride

Molebdinum

Term
Ultratrace Minerals
Definition

Nickel

Vanadium

Boron

Silicon

Arsenic

Term
Copper food sources
Definition

FOOD SOURCES:

liver

shellfish

nuts

seeds

mushrooms

soy

dark chocolate

Term

Copper

RDA

Definition
900 micrograms/day
Term

Copper

Daily Value

Definition
2 mg
Term

Copper

Upper Limit

Definition
10 mg/day
Term
Copper absorption
Definition

30-40%

Zinc and Copper compete for absorption

Term
Decrease Copper absorption
Definition

iron

magnesium

molybdenum

vitamin C

Term
Function of Copper
Definition

 

  • FUNCTIONS:
  • Component fo enzymes that consume oxygen or oxygen radicals
  • Regulate neurotransmitters like serotonin, tyrosine, dopamine and norepinephrine.

 

Term
Copper deficiency
Definition

RARE:

Can be found in premies and malnourished infants

Menkes disease

Term
Effects of copper deficiency
Definition

increased blood cholesterol

blood vessel damage

Term
Menkes disease effects
Definition

Cells absorb copper but cannot release into circulation.

Usually effects men in brain.

Term
Manganese food sources
Definition

FOOD SOURCES:

Whole grain cereals

nuts

legumes

tea

Term
Function of Manganese
Definition

 

  • similar to Cu and Zn
  • Found mostly in bones and metabolically active organs like liver, kidney and pancreas
  • Acts as coenzyme for many reactions

 

Term
Manganese deficiency
Definition
RARE
Term
Iodine/Iodide
Definition
Food source/body
Term
Iodine food sources
Definition

FOOD SOURCES:

saltwater seafood

iodized salt

molasses

dairy

Term
Most reliable and abundant source of Iodine in US Diet
Definition
Iodized salt
Term
Decrease bioavailability of Iodine
Definition
Goitrogens
Term
Function of Iodine
Definition

FUNCTIONS:

component of thyroxine and triodothyronine

Term
Iodine Deficiency
Definition

IDD (Iodine Deficiency Disorder)

Endemic goiter

Endemic cretenism

Term
Selenium food sources
Definition

FOOD SOURCES:

seafood

meats

cereal grains

nuts

Term
Function of selenium
Definition

FUNCTIONS:

Antioxidant

thyroid metabolism

glutathionin peroxidase

Term
Selenium deficiency
Definition
None known
Term
Chromium food sources
Definition

FOOD SOURCES:

Nutrient databases are inadequate:

processed meats, liver, eggs, whole grains

Term
Function of Chromium
Definition

FUNCTIONS:

May enhance insulin function

Part of carb and lipid metabolism

Term
Deficiency of Chromium
Definition
None known
Term
Fluoride food sources
Definition

FOOD SOURCES:

fluoridated water

tea

seafood

seaweed

Term
Amount of fluoride found in municipal water
Definition
0.2 mg/cup
Term
Function of fluoride
Definition

FUNCTIONS:

promote bone and dental health

Term
Fluoride deficiency
Definition
Associated with increased cavities
Term
Excessive fluoride intake can lead to 
Definition
fluorsis (mottling on teeth)
Term
Food sources of Molybdenum (Mo)
Definition

FOOD SOURCE:

plant based

Term
Function of Mo
Definition

FUNCTIONS:

Cofactor in enzymatic reactions

Part of metalloenzymes

Term
Cancer
Definition
Benign and malignant tumors that can metastasize
Term
Carcinogenesis
Definition

1. Initiation

2. Promotion

3. Progression

4. Metastasis

Term
Initiation State of Carcinogenesis
Definition
Exposure of cell to carcinogen
Term
Promotion state of carcinogenesis
Definition
Increased cell division of altered cells
Term
Progression stage of carcinogenesis
Definition
uncontrolled growth and formation of tumors
Term
Metastasis
Definition
cells travel to other sites in body and form tumors
Term
Factors that influence the incidence of cancer
Definition

Fruits and vegetables (↓)

Vitamin D and Ca intake (↓)

 

Obesity (↑)

Meat intake (↑)

Tobacco use (↑)

Alcohol abuse (↑)

Fried foods (↑)

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