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Nutrition
vitamins
44
Biology
Undergraduate 1
03/29/2009

Additional Biology Flashcards

 


 

Cards

Term
Carbs
Definition

DV 130: gm

Toxicity: N/A
Function: Satisfies Calorie Needs, Provides Energy

Source Rice, Bread, Potatoes, Pasta, Fruit

Deficiency

Term

Fat

Definition

DV 51.7-91.5 gm

Toxicity N/A

Source

Deficiency

Term
Fiber

 

Definition
DV 38  gm

Toxicity N/A

Source

Deficiency

Term
Protein
Definition
DV 56  gm  

Toxicity N/A

 Source

Deficiency

Term

Fat-Soluble Vitamins

Definition

A,D,K,E

• Fat-soluble vitamins

  • Not readily excreted (except vitamin K)
  • Can accumulate in the body
  • Absorbed along with fat
  • Carriers in the bloodstream – In lipoproteins
  • Storage in the liver & adipose tissue
  • Most is absorbed if there is enough fat
  • Fat malabsorption – May cause deficiency
Term
A
Definition

DV: 900 mcg RAE

Toxicity: 3000 (mcg)

Signs and symptoms

– Bone/muscle pain, loss of appetite, skin disorders,

headache, dry skin, hair loss, increased liver size,

vomiting

– Fetal malformation

– Possible permanent damage

 Effects of high carotenoid intake

Sources:Liver, Fortified Milk & Cereals

Function: Vision, Growth, Dry skin, Immune System,

 Acne medication

Deficiency: vision-skin conditions

Term
D
Definition

DV: 5-15 mcg

Toxicity: 50 (mcg)

– Over-absorption of calcium (hypercalcemia),

increase calcium excretion– Calcium deposits in organs and blood vessels– Growth retardation

Sources:Sun, Fortified Milk & Cereals, Fish Oil

Function: Ca, P absorption, Bone Calcium

Deficiency:

Rickets is the result of low vitamin D

Breastfed infants with little sun exposure

• Osteomalacia (soft bones)

– Rickets-like disease in adults

– Bones lose minerals and become porous

Term

E

Definition

DV: 15 mg

Toxicity:1000 (mg)

– Inhibit vitamin K metabolism andanticoagulants

– Possible hemorrhage

– Muscle weakness, headaches, nausea

Sources: Plant Oils, Greens, Fruits, Nuts, Fortified Cereals

Function:Antioxidant, Prevent A, Fatty acid Breakdown

Deficiency:

Breakdown of cell membranes

– Hemolysis

– Nerve degeneration

Term
K
Definition

DV: 90-120 mcg

Toxicity:

• Excess vitamins A and E

– Interferes with vitamin K– May cause hemorrhage and fractures• Newborns– Routinely injected with vitamin K– Breast milk is a poor source

• Toxicity unlikely; readily excreted

Sources:Green Veggies, Liver, Plant Oils

Function:Blood Clot Factors, Bone Metabolism Protiens

Deficiency:

Term
Water soluble Vitamins
Definition

• Dissolve in water

 

• Generally readily excreted from body

 

• Subject to cooking losses

 • B’s function as coenzymes  
Term
Thiamin-B1
Definition

DV:

– 1.1 mg/day for women

– 1.2 mg/day for men

Toxicity: non-toxic

Sources: Sunflower Seeds, Pork, Whole Grains, Beans, Peas

Function:

• Used to release energy from carbs

• Sensitive to alkalinity and heat

Deficiency: Beriberi

Term
Riboflavin-B2
Definition
DV:

– 1.1 mg/day for women

– 1.3 mg/day for men 

Toxicity Non-toxic

Function: Coenzyme - energy metabolism that need O2

Sources: Milk, Mushrooms, Spinach, Liver, Grains

Deficiency:

– Inflammation of mouth and tongue, dermatitis,

sensitivity to sun
Term
Niacin-B3
Definition

DV:

– 14 mg/day for women

– 16 mg/day for men

Toxicity:

        Upper Level is 35 mg/day

Sources:

Milk, Mushrooms, Spinach, Liver, Grains

Function:Coenzyme forms used in energy (fat

Deficiency:

– Pellagra

– 3 D’s

 Disease

Diarrhea

Dermatitis

Term
Pantothenic acid
Definition

DV: 5 mg

 

Toxicity: N/A

Sources: Mushrooms, Liver, Broccoli, Eggs

Function:

Part of Coenzyme-A– Essential for metabolism ofcarbohydrate, fat, and protein

Deficiency:

• Deficiency rare

– Usually in combination with otherdeficiencies
Term
Biotin
Definition

DV: 30 mcg

Toxicity: N/A

Sources:

Cheese, EggYolks, Cauliflower, Peanut Butter, Liver

Function:

• Co-enzyme

– Metabolism of carbohydrate and fat– Helps breakdown certain amino acids

Deficiency:

—rare

– Scaly, inflamed skin– Changes in tongue, lips– Decreased appetite, nausea, vomiting
Term
B-6 (pyridoxine)
Definition

DV: 1.3-1.7 mg

Toxicity: 100 mg

• Toxicity potential

– > 200 mg/day can lead to irreversible nervedamage

– Upper Level set at 100 mg/day

 Source: Animal foods, Organ Meats, Oysters, Clams, Fortified Cereal

Function:

Coenzyme of Folate Metabolism, Nerve Function

• Coenzyme forms– Metabolism of carbohydrate, fat, & proteinSynthesize

• nonessential amino acids• neurotransmitters

• hemoglobin and

WBC

– Role in homocysteine metabolism

- Alcohol increases vitamin B-6 destruction

Deficiency:

—rare– Scaly, inflamed skin– Changes in tongue, lipsDecreased appetite, nausea, vomiting
Term
Folate
Definition

DV: 400 mcg

Toxicity: N/A

Sources:

-Green Veggies, Orange Juice, Organ Meats, Sprouts     

  Function:  

• Coenzyme

– DNA synthesis– Homocysteine metabolism• Sensitive to:– Heat, oxidation, ultraviolet light

Deficiency:

– Affects RBC reproduction• Can’t carry oxygen as well• Megaloblast cells – immature RBCs• Megaloblastic Anemia• Neural tube defects
Term
B-12
Definition

DV: 2.4 mcg

Toxicity:N/A

Sources:

• Synthesized by bacteria, fungi & algae

• Animal products– Eggs– Milk– Organ meat• Stored primarily in the liver of animals• Synthetic form found in cereal & pills

Function:

• Coenzyme– Role in folate metabolism– Maintenance of the myelin sheaths

Deficiency:

• Deficiency– Pernicious anemia– Nerve degeneration and paralysis– Macrocytic anemia
Term
C
Definition

DV: 75-90 mg

Toxicity: 2 gm

• Excess excreted– Diarrhea common

Sources: Citrus Fruits, Strawberries, Broccoli, Greens Function:

• Synthesis of collagen

• Antioxidant– Reduces cancer-causing agents• Iron absorption• Immune functions– Doesn’t prevent colds, reduces symptoms

Neurotransmitter\Hormone\Connective Tissue Synthesis

• Synthesized by most animals fromglucose

– Not by humans

Deficiency:

• Scurvy

– Deficient for 20-40 days

– Fatigue, pinpoint hemorrhages– Bleeding gums

– Weakness– Fractures

– Associated with poverty

Term
Choline
Definition

DV:425-550 mg

Toxicity:3.5 gm

Sources:Widely distributed

Function:

• Essential nutrient, though not a vitamin

• All tissues contain choline

• Precursor for acetylcholine(neurotransmitter)

• Precursor for phospholipids

• Some role in homocysteine metabolism

Deficiency: Deficiency rare

 

Term
Major Minerals
Definition

 • Various functions in the body

• Major Minerals

– Require >100 mg /day

– Calcium, phosphorus

• Trace Minerals

– Require < 100 mg/day

– Iron, zinc

Term
Water
Definition

 DV Recommend:

9 cups for women

13 cupsfor men as a starting point

 

 

• Universal Solvent

• 50%-70% of body weight

• Muscle contains 73% water

– Fat contains ~20%

• Can’t survive long without it

 

 

Term
Water 2
Definition

Functions of water

• Body temperature regulation

– Water absorbs excess heat

– Body secretes fluid via perspiration

– Skin is cooled as perspiration evaporates

• Removal of body waste via urine– Urea excretion– Sodium excretion– Avoid concentrated urine

• Amniotic fluid, joint lubricants, saliva, bile

 

Term
Water 3
Definition

Hydration

• Loss of 1%-2% of body weight in fluid

– Thirst signal

• Loss of 4% of body weight causes muscleweakness

– Lose significant strength and endurance

• Loss of 10%-12%– Heat intolerance

• Loss of 20%= Coma and death

Over Dose

• Overburden the kidneys

• Low blood electrolyteconcentrations

• Blurred vision

Death>20%

Term
Mineral Bioavailability
Definition
 

 

• Degree of absorption

• Presence of binders and fiber

– Animal products are better absorbed

– Plants depend on mineral content of soil

• Refinement lowers mineral content

– More refined = less mineral content

Enriched = puts it back

Term
Minerals
Definition

• Various functions in the body

• Major Minerals

– Require >100 mg /day

– Calcium, phosphorus

• Trace Minerals

– Require < 100 mg/day– Iron, zinc

Term
Mineral Interactions
Definition

Fiber-Mineral

– Phytic & oxalic acid

– High fiber candecrease absorptionof iron, zinc, others

– Yeast can breakbonds

• Mineral-Mineral

– Competition forabsorption

– Size competition

• Mineral-Vitamin

– C enhances iron– D enhances Ca

Term
Trace Minerals
Definition

• Trace minerals are more toxic

– Gap between need & toxic is small

• Result of supplementation

– Don’t exceed UL long term

Look for the United States Pharmacopeia(USP)

-approved brands

Term
Sodium (Na)
Definition
DV: 1500 mg

Toxicity: 2300 mg

Sources:

Table Salt, Processed Foods, Condiments, Soups, Chips

Function:

Major + Ion of Extracellular Fluid, Nerve Impluse, Water Balance

• Table salt (NaCl): 40% sodium, 60% chloride

– 95% of ingested sodium is absorbed

• Positive ion in extracellular fluid

– Muscle contraction

– Conduction of nerve impulses

• Key for retaining body water

– Aldosterone regulates sodium balance

– Excretion regulated by the kidneys

• Aids in nutrient absorption

Deficiency:

Deficiency is rare

• Excessive perspiration

– Losing 2-3% of body weight

• Signs of deficiency:

– Muscle cramp, nausea, vomiting,dizziness, shock, coma

Term

Potassium (K)

 Positive ion in intracelluar fluid

Definition
DV: 4700 mg

Toxicity: N\A

Sources:

Spinach, Sqyash, Bananas, Orange Juice, Milk, Meat, Grains

Function:

Major + Ion of Intracellular Fluid, Nerve Impluse, Water Bal– Fluid balance

– Nerve impulse transmission

-Associated with lowering blood pressure

 

Deficiency:

– Muscle cramps, confusion, constipation, irregular heart beat, heart failure

 

Term

Chloride (Cl)

 Negative ion for extracellular fluid
Definition

DV: 2300 mg

Toxicity: 3600 mg

• High intake may cause high blood

pressure

Sources:

• Found in fruits and vegetables, Table Salt, Some Veggies, Processed Foods

Function:

– Immune response, nerve function

Major -  Ion of Extracellular Fluid, Stmach Acid, Nerve Imp

 

Deficiency: • Deficiency is rare
Term
Calcium (Ca)
Definition
DV: 1000- 1200 mg

Toxicity: 3-4 gm

Sources:

Bran, Green Veggies, Nuts, Chocolate, Legumes

Function:

-Bone Formation, Enzyme Function, Nerve & Heart Funtion

Absorption

– Requires slightly acidic environment and vitamin D

 

Deficiency:

• “A pediatric disease with geriatricconsequences”

• Leads to ~1.5 million fractures / year

• Slender, inactive women who smokeare most at risk

• “Less bones”

Term
Phoshporus (P)
Definition

DV: 700 mg

Toxicity: 3-4 gm

• Problem for individuals with inefficient

kidney function

• Phosphate ions bind calcium

– Chronic imbalance may lead to bone loss

Sources:

Dairy, Processed Food, Fish, Soft Drinks, Baked Foods, Meat

Function:

-Major Ion of Intracellular Fluid, Bone and Tooth, Metabolic

 

Deficiency: Deficiency unlikely
Term
Magnesium (Mg)
Definition
DV: 400-420 mg

Toxicity:350 mg

Sources: Bran, Green Veggies, Nuts, Chocolate, Legumes 

 Function: Bone Formation, Enzyme Function, Nerve & Heart  

• Nerve and heart functions

• 60% is stored in the bones

• Absorption based on body’s needs(normally 40%-60%)

• Cofactor for +300 enzymes

Deficiency: • Irregular heartbeat

• Weakness

• Muscle pain

• Disorientation

• Seizures

Term
Sulfur (S)
Definition
DV: N/A 

Toxicity: N/A

Sources: Protein Foods

Function:

Part of Vitamins and Amino Acids, Drug Detox, Acd/Bse Bal 

 

Deficiency: No deficiency or toxicity
Term
Iron (Fe)/tm
Definition
DV: 8 mg Toxicity:45 mg

• Serious, especially for children

• Signs:

– Diarrhea, constipation, nausea, abdominal pain

– Causes death due to respiratory collapse (shock) 

• Hemochromatosis

– Genetic disease

– Iron deposit that can lead to organ damage

 – May go undetected until organ damage at 50-60

Sources:

Meat, Seafood, Broccoli, Peas, Bran, Enriched Breads

Function:

(Components of Hemoglobin, Immune Function, Cognitive Dev)

• Hemoglobin in red blood cells

– Transports oxygen and carbon dioxide

– High turnover, high demand for iron

• Myoglobin in muscle cells

• Brain & Immune function

• Drug-detoxification pathway

• Bone health

Deficiency:

Iron deficient anemia

• Most common form of anemia

• Low levels of hemoglobin andhematocrit

• Insufficient intake and stores

• Reduction in

– Production of red blood cells

– Oxygen-carrying capacity

Term
Zinc (Zn)/tm
Definition
DV: 11 mg Toxicity:40 mg

• Inhibits copper metabolism

 • Possibly increases risk for prostate

cancer

 • Causes diarrhea, cramps, nausea,

vomiting

 • Depresses immune function
Sources:

Seafood, Meat, Greens, Whole Grains

Function:

(Required For Nearly 200 Enzymes, Growth, Immunity, Sex Dev)

• Cofactor to many enzymes

• DNA synthesis, growth, protein metabolism,wound healing

• Immune function• Bone & sexual organ development

• Insulin function

• Cell membrane structure and function

• Prevention of oxidative cell damage

• Slows macular degeneration

Deficiency:

• Symptoms

– Rash– Diarrhea

– No appetite

– Reduction in taste & smel

l– Hair loss

– Growth can be hampered

Term
Selenium (Se)/tm
Definition

DV: 55  mcg

Toxicity:400 mcg

• Garlicky breath• Hair loss

• Nausea, vomiting

• Weakness• Rashes

• Cirrhosis of the liver

Sources:

Meats, Eggs, Fish, Seafood, Whole Grains

 Function:

(Antioxidant)

– Co-factor for glutathione peroxidase

 – Protects the heart and other cells from

oxidative damage

  – Works together with vitamin E

 • Thyroid hormone metabolism

Deficiency:

• Muscle pain 

• Muscle wasting 

• Weakness

 • Deterioration of heart muscle

Term

Iodide (I)/tm

 

Definition
DV: 150 mcg

Toxicity: 1.1 mg

Sources: Iodized Salt, White Bread, Saltwater Fish, Dairy

Function: Component of Thyroid Hormone 

– Supports thyroid hormone synthesis

– Regulates metabolic rate, growth, development

Deficiency: – Thyroid gland enlarges (goiter) due to low intake– Cretinism, stunting of fetal growth and mentaldevelopment as a result of low iodide in maternaldiet

Term
Copper (Cu)/tm
Definition
DV: 900 mcg RAE

Toxicity: 8-10 mg

Sources: Liver, Cocoa, Beans, Nuts, Whole Grains, Dried Fruits

Function:

Iron Metabolism, Antioxidant Enzymes, Protein Met Synthesis

• Aids in iron metabolism

• Part of connective tissue protein

• Cofactor for antioxidant enzymes

• Immune system function

• Blood clotting

• Blood lipoprotein metabolism

Deficiency:

• Anemia

• Decreased WBC

• Bone loss

• Inadequate growth

• Cardiovascular disease

Term
Fluoride (F)/tm
Definition
DV:3.8 mg

Toxicity: 10 mg

Sources:

Fluoridated Water, Toothpaste, Tea, Seaweed

Function:

Helps Keep Teeth Intact, Protects From Dental Caries

• Role in prevention of dentalcaries

– Helps tooth enamel resist acid

– Inhibits bacterial growth

Deficiency:

• Upper Level is 1.3-2.2 mg/day for

children

• Upper Level is 10 g/day for olderchildren and adults

• Mottling of teeth in children

• Limit toothpaste to pea size for children

– High amounts can weaken teeth

Term
Chromium (Cr)/tm
Definition
DV: 25-35 mcg

Toxicity: N/A

Sources: Egg Yolks, Whole Grains, Pork, Nuts, Mushrooms, Beer Function: Insulin Action

• Enhances insulin action

– Role in Type 2 diabetes?

Deficiency:

• Low intake:

– Impaired glucose tolerance– Elevated blood cholesterol and

triglycerides

Term
Manganese (Mn)/tm
Definition
DV: 1.8-2.3 mg

Toxicity:11 mg

Sources:

Nuts, Oats, Beans, Tea

Function:

– Cofactor in carbohydrate metabolism

– Component of superoxide dimutase

– Role in bone formation

Deficiency: • No deficiency symptoms observed in humans
Term
Molybdenum (Mo)/tm
Definition
DV: 45 mg

Toxicity: 2 mg

Sources: day Beans, Grains, Nuts

Function: Enzyme Action

 

Deficiency: • Deficiency rare– Increased heart and respiration rates– Night blindness, mental confusion– Edema, weakness, coma
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