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-Proteins made of chain of amino acids -Proteins are organic compounds containing C, H, O, and N -N distinguishes protein from carbohydrates and fats |
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-20 common amino acids needed to form all proteins in human body -9 of these amino acids considered essential -Other 11 amino acids nonessential |
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Four Major Functions of Proteins |
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1. Integral structural component of skeletal muscle, bone, connective tissues, organs, red blood cells, hemoglobin, hair, & nails 2. Basic substance that makes up enzymes & hormones in human body 3. Growth, maintenance & repair of protein-containing structures 4. Protein also serves as an energy source |
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-Nearly all in U.S. get enough protein -Most consume more than needed -Recommended range of total calories: 10-35% |
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Acceptable Macronutrient Distribution Range (AMDR) |
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Carbohydrate: 45-65% total calories Protein: 10-35% total calories Fat: 20-35% total calories |
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Food as a Source of Protein |
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-70% protein intake comes from meats, milk, and other animal products in U.S. diet -Fruit has no protein…. Protein and carb have 4 cals/gram… fat has 9 cals/gram… alcohol has 7 cals/gram -Gramsx4=calories in protein |
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Review of Protein Digestion and Absorption |
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-Digestion: protein → amino acids -Mechanical digestion starts in mouth -Chemical digestion starts in stomach -Two key enzymes: trypsin and pepsin -Absorption occurs in small intestine |
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Protein as an Energy Source |
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-If destined for energy use, first needs nitrogen removed from individual amino acids -Excess free nitrogen excreted in urine -Nitrogen excretion increases need for water |
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-Most protein recycled from protein substances being ‘turned over’ in our body -Proteins key roles in tissue repair & replacing tissue proteins damaged by illness or injury |
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-Chain of amino acids called polypeptide -Chains of amino acids fold up into complex shapes -DNA directs protein synthesis and order of amino acids in chains, which determines type and function of protein formed |
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-Change in shape of protein structure due to heat, light, change in pH (too acidic or basic environment), alcohol, or motion -Examples in food: Boiling foods or beating egg white; Adding lemon juice or vinegar -Examples of effects in body: Hemoglobin less able to carry oxygen & Enzymes less able to function as catalyst |
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-Quality of protein varies depending on its essential amino acids content -High quality proteins contain all essential amino acids -Individual amino acids not stored in body -If one or more essential amino acids missing in diet, proteins synthesis halted |
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Complete & Incomplete Proteins |
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-Food sources of high-quality protein (complete proteins) found in animal derived products -Incomplete proteins – deficient in one or more essential amino acids -What about vegetarian diets: Complementary Protein Sources -Rice & Black Beans -Hummus and Bread -Corn and Black-eyed peas -Bulgur and Lentils -Tofu and rice -Corn and Lima beans -Tortilla with refried beans -Pea soup and bread |
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-2/3 of U.S. populations’ protein sources come from animal products -Wealth leads to increase meat protein intake along with increase consumption of fat -High protein intake usually accompanied by higher-fat & lower-fiber intakes -Diets adequate in protein without excess fat tend to be rich in beans & grains mixed with lean meats & low-fat dairy products -Foods high in complete protein, such as hamburger, cheese, nuts, & eggs, also high in fat & little or no fiber content -Even lean meats can provide large part of total calories from fat -Actually noticed that rates of heart disease & some cancers increase with higher protein intakes |
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-Protein deficiency occurs alone or with deficiency of calories & other nutrients -Protein foods good sources of micronutrients iron, zinc, niacin, & vitamin B12 -Body protein provides energy during starvation states -Loss of 30% body protein results in decrease strength for breathing, increasing susceptibility to infection, abnormal organ functions, & death - Problem with starvation: taking protein from liver, intestines, heart, muscles, & other organs and tissue |
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-Malnutrition caused by insufficient protein intake, yet adequate total caloric intake -Gives “fat” or swollen appearance -May develop after child weaned from breast milk or in severe alcoholics |
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-Malnutrition caused by insufficient total protein & caloric intakes -Also called protein-energy malnutrition -Gives “skin and bones” appearance -Occurs among people with anorexia nervosa & diseases causing cachexia |
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Kwashiorkor & Marasmus are complicated by: |
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Infection, Diarrhea, Dehydration |
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-Adults can consume up to 35% of total calories from protein without ill effects -Consumption of 45% or greater of total calories from protein is too high -Excess protein intake causes nausea, weakness, and diarrhea; diets very high in protein result in death after several weeks -Disease from excess protein intake termed “rabbit fever” -High protein diets implicated in weak bones, kidney stones, cancer, heart disease, & obesity -NAS concluded safe range for protein intake is 10-35% of total calories |
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-High intakes of individual amino acid supplements can harm health by disrupting protein synthesis -Amino acid supplements: o May cause loss of appetite, diarrhea, & GI upsets o Increase workload of liver and kidneys, & likelihood of dehydration |
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-Amino acids & protein powders alone do not cause muscle growth -Only combination of exercise & good diet build muscle mass -Most athletes get sufficient protein from their usual diet -May benefit from additional 15 gram daily over RDA -AA’s not delivered directly to our muscles or causing muscles to enlarge -Think about diet being higher in total calories as well – so percentage of protein may not be higher, but increased intake |
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