Term
What subjects are interrelated to pharmacology? |
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Definition
Anatomy & physiology, chemistry, pathophysiology |
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Term
Give an example of Stage IV testing (post-marketing surveillance). |
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Definition
Vioxx, others pulled from market |
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Term
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Definition
Dispensing of drugs to patients after examined by licensed HCP. |
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Term
Give an example of a bioterrorist threat. |
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Definition
Anthrax contamination, incapacitating chemical / radiation exposure |
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Term
What is the biggest disadvantage of OTC drugs? |
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Definition
SEs unknown by public, wrong drug for problem, not diagnosed “self-diagnosed” |
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Term
What is the mechanism of action for a diuretic used to treat hypertension? |
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Definition
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Term
What category of scheduled drugs has the lowest abuse potential? |
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Definition
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Term
The therapeutic classification focuses on what a drug does clinically. T or F |
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Definition
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Term
What drug category is considered the most harmful for the unborn fetus? |
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Definition
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Term
All OTC drugs are safe for pregnant women. T or F |
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Definition
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Term
How does a sublingual drug work? |
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Definition
Enters the blood stream directly |
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Term
How could nausea associated with some medications be minimized? |
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Definition
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Term
What would happen if one applied a topical medication to dry, cracked skin? |
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Definition
Systemic absorption / SEs, irritation |
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Term
What would be the most harmful problem that could occur from administration of a local anesthetic (besides anaphylaxis)? |
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Definition
Systemic side effects from absorption into the general circulation |
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Term
What drug administration method is used to administer Insulin? |
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Definition
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Term
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Definition
Drug available to produce a biological response |
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Term
What does a longer half-life mean? |
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Definition
Stays in the body longer – short t1/2 would be eliminated quicker |
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Term
Which pharmacologic phase would MOST affect patients with liver disease? |
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Definition
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Term
Why do geriatric patients have altered sensitivity to drug therapy? What other group is affected similarly? |
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Definition
Reduced liver enzyme activity |
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Term
What is the first-pass effect? |
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Definition
Only a portion of the drug dose reaches the target tissue/organ due to liver metabolism of drugs known as the first pass effect. |
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