Term
| HMG-CoA Reductase Inhibitors |
|
Definition
Atorvastatin (Lipitor)
Lovastatin (Mevacor)
Simvastatin (Zocor)
Pravastatin (Pravachol)
Rosuvastatin (Crestor) |
|
|
Term
HMG-CoA Reductase Inhibitors(Statins)
Atorvastatin (Lipitor)
Lovastatin (Mevacor)
Simvastatin (Zocor)
Pravastatin (Pravachol)
Rosuvastatin (Crestor) |
|
Definition
| GI distress, headache, dose-related increase in liver enzymes, rhabdomyolysis (disintegration of striated muscle fibers). |
|
|
Term
HMG-CoA Reductase Inhibitors(Statins)
Atorvastatin (Lipitor)
Lovastatin (Mevacor)
Simvastatin (Zocor)
Pravastatin (Pravachol)
Rosuvastatin (Crestor) |
|
Definition
| Take at bedtime for greater effectiveness as cholesterol is synthesized mostly at night |
|
|
Term
HMG-CoA Reductase Inhibitors(Statins)
Atorvastatin (Lipitor)
Lovastatin (Mevacor)
Simvastatin (Zocor)
Pravastatin (Pravachol)
Rosuvastatin (Crestor) |
|
Definition
| Report unexplained muscle tenderness or weakness especially with concurrent fever or dark red-brown urine (rhabdomyolysis). |
|
|
Term
Niacin
Simvastatin (Zocor)
Pravastatin (Pravachol)
Rosuvastatin (Crestor) |
|
Definition
| Dose related flushing of face, ears, and neck. |
|
|
Term
|
Definition
| Transient headache, blurred vision, tingling of extremities |
|
|
Term
|
Definition
| GI distress, hyperglycemia, orthostatic hypotension, elevated homocysteine levels. |
|
|
Term
|
Definition
| Teach patient to take med with cold beverage to reduce risk of flushing |
|
|
Term
| HMG-CoA Reductase Inhibitors(Statins); Niacin; Ezetimibe (Zetia) |
|
Definition
|
|
Term
|
Definition
| Take aspirin 30 minutes before niacin to reduce persistent flushing |
|
|
Term
|
Definition
| treat elevated homocysteine with folic acid. |
|
|
Term
|
Definition
Fenofibrate (TriCor)
Gemfibrozil (Lopid) |
|
|
Term
Fibric Acid Derivatives
Fenofibrate (TriCor)
Gemfibrozil (Lopid) |
|
Definition
| Hypokalemia, hyperglycemia. Elevated liver enzymes |
|
|
Term
Fibric Acid Derivatives
Fenofibrate (TriCor)
Gemfibrozil (Lopid) |
|
Definition
| Decreased libido, impotence |
|
|
Term
Fibric Acid Derivatives
Fenofibrate (TriCor)
Gemfibrozil (Lopid) |
|
Definition
| Report sexual dysfunction as drug dose may be changed or another antilipidemic may be ordered |
|
|
Term
|
Definition
Cholestyramine (Questran)
Colestipol (Colestid)
Colesevelam (WelChol) |
|
|
Term
Bile-Acid Sequestrants
Cholestyramine (Questran)
Colestipol (Colestid)
Colesevelam (WelChol) |
|
Definition
| Reduce cholesterol and LDLs in approximately 1 week. |
|
|
Term
Bile-Acid Sequestrants
Cholestyramine (Questran)
Colestipol (Colestid)
Colesevelam (WelChol) |
|
Definition
| Alteration in taste. Constipation. |
|
|
Term
Bile-Acid Sequestrants
Cholestyramine (Questran)
Colestipol (Colestid)
Colesevelam (WelChol) |
|
Definition
| Encourage increased fluid intake and fiber to prevent constipation. |
|
|
Term
| Cholesterol Absorption Inhibitor |
|
Definition
|
|
Term
Cholesterol Absorption Inhibitor
Ezetimibe (Zetia) |
|
Definition
| Inhibits cholesterol absorption in small intestinal |
|
|
Term
Cholesterol Absorption Inhibitor
Ezetimibe (Zetia) |
|
Definition
| Headache. Mild GI distress. Dose-related increase in liver enzymes. Angioedema. Thrombocytopenia |
|
|
Term
Cholesterol Absorption Inhibitor
Ezetimibe (Zetia) |
|
Definition
| Use with caution for patients with liver dysfunction. |
|
|
