Term
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Definition
- chemicals in the body that affect other organs
- Negative feedback system
- interaction between the nervous system and endocrine system
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Term
| Negative feed back system is ? |
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Definition
- where the chemical stimulates a target tissue to respond and then at a certain level stop the response
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Term
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Definition
| secrete hormone directly into the bloodstream |
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Term
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Definition
| secrete hormone thru ducts |
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Term
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Definition
- Hypothalamus secretes TRH which stimulates the Ant pituitary which secretes TSH which stimulates the thyroid which secretes T3 and T4 as they increase the TSH decreases (neg feed)
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Term
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Definition
- triiodothyronine and thyroxine - both require iodine
- control cellular metabolism
- influence cell replication
- important for brain and normal growth
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Term
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Definition
- secreted by the thyroid
- secreted when serum calcium levels ↑
- ↓ serum calcium levels by ↑ bone absorption
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Term
| Diagnostic tests for the thyroid ? |
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Definition
- serum thyroid stimulating hormone (tsh)
- serum free T4 - done to confirm abnormal tsh
- serum t3 and serum t4 - illness and meds
- thyroid antibodies - ↑ autoimmune thyroid ds
- thryoid scan
- biopsy
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Term
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Definition
- hypothryoidism
- during fetal and neonatal development
- stunted mental growth
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Term
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Definition
- ↑ TSH levels and ↓ T4 levels
- women 5x more then men
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Term
| Cx of Hypothyroidism are ? |
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Definition
- atrophy of the gland with aging - elderly women
- hashimotos dx - autoimmune
- post tx for hyperthyroidism
- medications
- iodine deficiency
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Term
| early S/S of hypothyroidism are ? |
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Definition
- extreme fatigue
- numbness and tingling of fingers
- hair loss brittle nails dry skin
- hoarseness
- menstrual changes / libido loss
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Term
| late S/S of hypothryoidism are ? |
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Definition
- neuroligic
- enlarged tongue hands and feet
- constipation
- weight gain
- impaired ventilation
- cad, atherosclerosis, slowed pulse
- hypothermia cold intolerance
- thickened skin hair loss mask face
- sleep apnea
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Term
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Definition
| refers to symptoms of severe hypothryoidism |
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Term
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Definition
| very high mortality even with treatment |
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Term
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Definition
- synthetic levothyroxine - synthroid, levothroid
- to rapid replacement could cause angina and MI
- ↑ blood glucose levels
- ↑ effects of digoxin, coumadin, indomethacin
- ↑ effects of synthroid when taken with dilantin, tricyclic antidepressants
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Term
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Definition
- hyperthryoidism
- most common type
- autoimmune disorder
- women 8x more than men
- ages 20-40
- after emotional shock stress infection
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Term
| S/S of hyperthyroidism are ? |
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Definition
- nervousness, hyperexcitable, irritable
- palpitations, tachycardia, HTN
- heart failure, A-fib
- heat intolerance
- skin flushed warm moist
- exophthalmos
- weight loss
- muscular fatigue, weakness
- amenorrhea
- osteoporosis and fx in elderly
- enlarged thyroid
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Term
| tx for hyperthyroidism is ? |
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Definition
- medications
- PTU- propylthiouracil
- tapazole - methimazole
- iodide compounds - lugos solution sski ki
- inderal
- radioactive iodine
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Term
| Hyperthyroidism Thyroid storm is ? |
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Definition
- severe form with abrupt onset
- fatal if not treated
- high fever
- tachycardia
- server symptoms of hyperthyroidism
- hypothermia blanket, iv fluids o2, ptu/tapazole
- iodine inderal digoxin
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Term
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Definition
- benign or malignant
- symptoms of thyrotoxicosis
- quality of enlargment goiter
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Term
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Definition
- iodine deficient goiter - tx iodized salt
- nodular goiter - overgrowth of gland, tx sx
- thyroid cancer - tx sx
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