Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| Ibuprofen (Motrin, Advil) |
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Definition
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Term
| Naproxen (Naprosyn, Anaprox, Aleve) |
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Definition
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Term
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Definition
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Term
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Definition
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Term
| decreased GI complications short term, but not long term; increased cardiovascular risk; possible cross sensitivity with sulfa allergies |
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Definition
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Term
| avoid in patients with renal failure or in high risk of bleeding; treatment should not exceed 5 days |
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Definition
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Term
| NSAIDs Black Box Warnings |
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Definition
| increased risk of serious CV thrombotic events, MI, stroke; CI for txt of peri-operative pain in the setting of CABG surgery |
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Term
| preferred for the short term before NSAIDs to reduce CV events |
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Definition
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Term
| preferred NSAID to be used |
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Definition
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Term
| used in NSAID patients at increased risk of GI ulceration |
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Definition
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Term
| NSAIDs effect on the afferent arteriole |
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Definition
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Term
| constriction of the afferent arteriole |
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Definition
| decreases renal blood flow leading to renal decompensation |
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Term
| NSAID constriction on the afferent arteriole causes impairment of GFR |
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Definition
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Term
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Definition
| Synergistic with acetaminophen and/or opioids; Ceiling effect; not recommended in heart failure; use caution with warfarin |
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