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NRSG 345 Exam 4
Pain & Respiratory
172
Nursing
Undergraduate 3
11/26/2012

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Term
scientific definition of pain
Definition
an unpleasant sesory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage
Term
affective/emotional dimension of pain
Definition
concurrent feelings of anger, fear, depression, and anxiety that can make pain better wor worse
Term
behavioral dimension of pain
Definition
activities that express pain or are performed to control pain and how pain interferes with normal daily activities/behaviors
Term
cognitive dimension of pain
Definition
beliefs, attitudes, memories, expectations, and goals related to the pain and pain control
Term
sociocultural dimension of pain
Definition
factors such as age, gender, etc. that influence one's perceptions, beliefs, and means of coping with and managing pain
Term
spiritual dimension of pain
Definition
factors include religious beliefs and existential beliefs/outlook
Term
physiological dimension of pain
Definition
includes transmission, perception, modulation of pain related to physical and neuro-chemical processes
Term
nociceptive pain
Definition
processing of stimuli that damages normal tissues
Term
somatic pain
Definition
pain which arises from bone, join, muscle, skin, or connective tissue
Term
visceral pain
Definition
pain which arises from visceral organs
Term
neuropathic pain
Definition
pain related to disease or dysfunction of the nervous system
*not well controlled by opioids alone
Term
nociception
Definition
physiologic process by which info about tissue damage is communicated to the CNS
Term
nociceptors
Definition
pain receptors
Term
A-fibers
Definition
large, myelinated, rapid conduction, precise localization, sharp pain
Term
C-fibers
Definition
small, unmyelinated, slow conduction, poor localization, diffuse aching/burning pain
Term
4 steps of pain transmission
Definition
1. transduction
2. transmission
3. perception of pain
4. modulation
Term
transduction
Definition
1st step of pain transmission
occurs in the periphery when a stimulus causes tissue damage; celles release a substance that sensitize nociceptors and an action potential is generated
Term
transmission
Definition
2nd step of pain transmission
action potential continues from the site of injury to the spinal cord and the brain
Term
perception of pain
Definition
3rd step of pain transmission
conscious experience of pain
Term
modulation
Definition
4th step of pain transmission
inhibition of nociceptive impulses in the brain stem and then the spinal cord to inhibit the transmission of nociceptive impulses
Term
sensitizing substances of transduction
Definition
prostaglandins, bradykinin, serotonin, substance p, histamine
Term
inhibition substances of modulation
Definition
endogenous opioids, serotonin, norepinephrine
Term
acute pain
Definition
lasts less than 3 months
Term
chronic pain
Definition
gradual or sudden onset that continues 6 months or more past the normal recovery time
Term
most reliable indicator of pain
Definition
patient's self report
Term
least sensitive indicators of pain
Definition
physiologic measures such as changes in HR, BP, etc.
Term
hierarchy of pain assessment techniques
Definition
1. obtain self-report
2. search for potential causes of pain
3. observe patient behavior
4. proxy reporting
5. attempt an analgesic trial
Term
sensory component of pain
Definition
Pattern
Area
Intensity
Nature
Term
assessing pain patter
Definition
onset, duration, variations, associated symptoms
Term
assessing pain area
Definition
referred, dermatome
Term
measuring pain intensity
Definition
numerical, visual, faces
Term
5th vital sign
Definition
the joint commission requires pain to be documented and considers it to be this
Term
opioids
Definition
mimic endogenous neuropeptieds that inhibit transmission ofpain impulses in the central and peripheral nervous system
Term
tolerance
Definition
characterized by the need for an increased opioid dose to maintain the same degree of pain relief
Term
physical dependence
Definition
an expected physical response manifested by a withdrawal syndrome that occurs when blood levels of the drug are abruptly decreased
Term
early withdrawal reponse (6-12 hrs)
Definition
characterized by anxiety, chills, tremors, diaphoresis
Term
late withdrawal response (48-72 hrs)
Definition
characterized by diarrhea, restlessness, nausea, vomiting, insomnia
Term
respiratory depression
Definition
side effect of opioids that is most common in first days and tolerance usually develops within 1 week; preceded by sedation
Term
respiratory depression risk factors
Definition
opioid naive patients, obesity, sleep apnea, respiratory compromise, etc.
Term
Narcan
Definition
opioid antagonist used to reverse respiratory depression or somnolence
Term
Narcan side effects if reversal too rapid
Definition
severe pain, profound onset of withdrawal, seizures, arrhythmias, acute pulmonary edema
Term
constipation
Definition
side effect of opioids that patients do not typically develop a tolerance to
Term
Meperidine (Demerol)
Definition
Term
Fentanyl Patch (Duragesic)
Definition
for opioid sensitized patients with chronic pain; takes 12-18 hours to reach peak effect and to clear from system; do NOT heat
Term
Tramadol
Definition
weak binding to mu-opioid receptors and inhibition of reuptake of NE & seratonin to produce opioid-like effects with less respiratory depression
Term
Propoxyphene (Darvon)
Definition
weak oral opioid with toxic metabolites, long half-life that has been withdrawn from the market
Term
NSAIDs
Definition
analgesic, anti-inflammatory, anti-platelet that can cause GI bleeding
Term
Acetaminophen
Definition
analgesic that is not anti-inflammatory or anti-platelet but does not cause GI upset; can cause liver injury
Term
Ketorolac
Definition
only injectable NSAID that can't be used more than 5 days due to renal implications
Term
black box warning of NSAIDs
Definition
may cause an increased risk of serious CV thrombotic events, MI, and stroke
Term
adjuvant therapy
Definition
drugs that provide non-tranditional analgesia that can be combined with pain meds, especially for neuropathic pain
Term
Anticonvulsants/Antiepileptic drugs
Definition
used to treat nueropathic pain and migranes by suppressing the spontaneous firing of action potentials that signal pain because the neuronal excitability is dampened
Term
Antidepressants
Definition
block reuptake of NE & serotonin which enhances the action of inhibitory pain pathways; stabilizes neuron membrane through inhibition of Na channels
Term
Local Anesthetics
Definition
decrease neuronal excitability at sodium channels
Term
WHO analgesic step 1
Definition
mild pain (1-3); treat with nonopiod, adjuvant
Term
WHO analgesic step 2
Definition
moderate pain (4-6); treat with opioid (codeine, hydrocodone, oxycodone)
Term
WHO analgesic step 3
Definition
moderate to severe pain (7-10); treat with powerful opioids (morphine, fentanyl, hydromorphone)
Term
PCA
Definition
pain medication has a basal rate and a bolus that can be administered by the patient as needed
Term
basal rate
Definition
continuous infusion of IV opioid in PCA
Term
bolus (demand dose)
Definition
patient can self-administer a pre-set amout of opioid on demand in a PCA
Term
lock out time
Definition
pump is set to control the minimum interval between doses
Term
around the clock (ATC) scheduling
Definition
medications are scheduled continulously to be more effective than PRN dosing
Term
placebos
Definition
these are NOT to be used to assess the nature of pain
Term
allodynia
Definition
pain produced by ordinarily innoculous stimuli
Term
hyperalgesia
Definition
exaggerated response to pain
Term
nociceptor classifactions
Definition
thermo, chemical & mechano
Term
ORAL
Definition
best administration for managment of chronic pain
Term
abstinance syndrome
Definition
develops if a drug is abruptly withdrawn or an antagonist were added
Term
addiction
Definition
a psychological phenomenon characterized by drug craving, overwhelming concern with drug acquisition, aberrant behavior, or unsanctioned dose escalation
Term
bronchial
Definition
heard over large airways, "tubular"
Term
vesicular
Definition
heard over most of the lung field
Term
fine crackle
Definition
caused by alveoli/airway opening
Term
coarse crackles
Definition
caused by airway opening and secretions
Term
wheeze
Definition
caused by airway narrowing, secretions
Term
ronchi
Definition
caused by airway secretions & narrowing, but usually clear after caughing
Term
crepitance
Definition
air under the surface of the skin
Term
rub
Definition
pleural spaces around the lungs rubbing against one another
Term
FiO2
Definition
percentage or fraction of air breathed that is oxygen
Term
oxygen toxicity
Definition
respiratory tissue damage as a result of prolonged exposure to high FiO2
Term
CO2 narcosis
Definition
too much O2 can decrease ventilatory rate and cause tissue damage; s/s include somnolence, confusion, coma
Term
hypoxemia
Definition
oxygen in the blood is low
Term
60 or less
Definition
PaO2 reading meaning hypoxemia
Term
90% or less
Definition
SpO2 reading meaning hypoxemia
Term
>6L
Definition
at what oxygen flow can you no longer use bubble to humidify?
Term
change the colored adaptor
Definition
to increase FiO2 when using a venturi mask you must do this
Term
oxy mask
Definition
open face design, feels less restrictive
Term
non-rebreather
Definition
mask with a bag reservoir ~60-90% FiO2
Term
40-60 lpm
Definition
flow rate of a high flo nasal canual
Term
metered dose inhalers
Definition
portable, beta2 agonists, anticholinergic, or corticosteroid; always use a spacer!
Term
dry powder inhalers
Definition
steroids or combinations in a disk
Term
Combivent Respimat inhaler
Definition
no propellant or inhalers, more efficient, no spacer needed, mist
Term
pulse oximeter
Definition
measures oxygen saturation of the blood by measuring the % of Hgb molecules saturated with oxygen
Term
capnography
Definition
CO2 content in exhaled gas
Term
CPAP
Definition
one pressure, requires spontanuous breathing
Term
BiPAP
Definition
inspiratory and expiratory phases for tighter control of tidal volume and better ventilation
Term
CDB
Definition
technique patient is able to do to mobilize secretion
Term
acapella "pickle"
Definition
vibratory therapy to mobilize secretions and increase thoracic pressure
Term
3 components of chest physiotherapy
Definition
1. positioning (postural drainage)
2. percussion
3. vibration
Term
partial pressure
Definition
the pressure exerted by an individual gas in a misture of gases; indicates how much gas is dissoved in the blood
Term
ventilation
Definition
movement of air into and out of the lungs
Term
perfusion
Definition
distribution of blood to the lungs
Term
diffusion
Definition
movement of gases across the respiratory membrane
Term
hypoxemia requirements
Definition
decreased oxygen tension of arterial blooed due to (need all 3) 1. altered ventilation 2. altered perfusion 3. altered diffusion
Term
hypercapnea
Definition
elevated partial pressure of CO2 in the arterial blood related to hypoventilation of alveoli
Term
dyspnea
Definition
a subjective sensation of uncomfortable or difficult breating
Term
ventilation/perfusion ratio (V/Q ratio)
Definition
relationship between ventilation and perfusion of the lungs
Term
1
Definition
perfect V/Q ratio
Term
0.8 - 1
Definition
normal V/Q ratio
Term
intrapulmonary shunting
Definition
well-perfused pulmonary capillaries surround poorly ventilated alveoli affecting V/Q ratio
Term
pulmonary vasculature obstruction
Definition
well-ventilated alveoli are surrounded by poorly perfused capillaries affecting V/Q ratio
Term
atelectasis
Definition
collapse of lung tissue at any structural level
Term
compression atelectasis
Definition
caused by external pressure by tumor, fluid, or air in the pleural space
Term
absorption atelectasis
Definition
alveolar collapse resulting from the removal of air into the blood stream from alveoli distal to an obstruction
Term
adhesive (surfactant) atelectasis
Definition
collapsed lung tissue due to insufficient surfactant increasing surface tension and resulting in airway collapse
Term
s/s of atelectasis
Definition
dyspnea, dullness, cough, decreased breath sounds, fever
Term
leukocytosis
Definition
late sign of atelectasis
Term
bronchitis
Definition
infection of mucous membranes in bronchial trees
Term
bronchopneumonia
Definition
infection of alveoli & bronchials
Term
pneumonia
Definition
infection of lung perichymal
Term
pneumonia
Definition
most common infectious cause of death in the US
Term
routes of microorganism invasion
Definition
1. inhalation
2. bloodstream from another site
3. aspiration
Term
community acquired pneumonia (CAP)
Definition
pneumonia diagnosed within 2 days of admit
Term
community acquired pneumonia
Definition
pneumonia usually associated with staph so s/s include abrupt onset of fever and chills
Term
ventilators
Definition
leading cause of healthcare acquired pneumonia
Term
healthcare acquired pneumonia (HAP)
Definition
pneumonia diagnosed 48+ hours after admission
Term
s/s of bacterial pneumonia
Definition
fever, tachycardia, tachypnea, cough, etc.
Term
stages of pneumonia
Definition
1. hyperemia
2. red hepatization
3. gray hepatization
4. resolution
Term
macrolide OR doxycycline
Definition
antibiotic therapy for previously healthy client with pneumonia
Term
Fluoroquinolone OR B-lactam plus macrolide
Definition
antibiotic therapy for client with comorbidities
Term
tendon rupture
Definition
black box warning of fluoroquinolone
Term
B-lactam PLUS another antibiotic (usually double doses)
Definition
antibiotic therapy in the ICU
Term
good lung down
Definition
positioning of a patient with pneumonia for proper drainage
Term
Legionella pneumonia
Definition
pneumonia caused by contaminated water in cooling/air conditioning systems
Term
pneumocystis jiroveci
Definition
opportunistic infection caused by a fungus in immunodificient patients (not found in healthy people)
Term
bacterial pneumonia
Definition
sudden onset, rigors common, productive cough, pleuritic pain common, dull percussion, localized x-ray, WBC >15,000/mm3
Term
viral/atypical pneumonia
Definition
gradual onset, headache common, rigors rare, nonproductive cough, pleuritic pain rare, minimal physical findings, diffuse x-ray, WBC <15,000/mm3
Term
transmission of TB
Definition
1. airborne
2. remains viable for 8 months
3. prolonged exposure
Term
TB pathophysiology
Definition
multiplies in alveoli, surrounded by PMNs and macrophages
Term
Latent TB
Definition
inactive bacilli, skin test positive, x-ray normal, sputum smears negative, asymptomatic
Term
TB disease
Definition
active bacilli in body, skin test positive, x-ray abnormal, sputum smears positive, symptomatic (cough, fever, wt loss), infections
Term
extrapulmonary TB (disseminated)
Definition
TB spread by blood or lymph to any system
Term
TB classification 0
Definition
no TB exposure, not infected
Term
TB classification 1
Definition
TB exposure, no evidence of infection
Term
TB classification 2
Definition
TB infection, no TB disease (latent)
Term
TB classification 3
Definition
TB, clinically active
Term
TB classification 4
Definition
previous TB disease (not clinically active)
Term
TB classification 5
Definition
TB suspected
Term
tuberculin skin test
Definition
0.1mL intradermal injection of a TB "purified protein derivative"
*to be positive, exposure must have been at least 2-3 months ago
Term
two step TB testing
Definition
"booster" phenomenon is used to detect false negatives by using the PPD antigen to reawaken/enhance immune response to antigen
Term
induration
Definition
sign of a positive skin test reaction
Term
BCG vaccine
Definition
vaccine used for TB prevention that will cause a positive skin test
Term
QuantiFERON-TB Gold test
Definition
lab test diagnosing latent TB by incubating blood with antigen and measuring interferon-gamma released from WBCs
Term
s/s of TB
Definition
low-grade fever, chills, night sweats, fatigue
Term
chest x-ray of TB
Definition
reveals nodules in UPPER lobes
Term
1. 3 consecutive negative sputum samples
2. treated 2+ weeks
3. symptoms reduce/improve
Definition
3 requirements for being considered non-infectious of TB
Term
1. isoniazid*
2. rifampin*
3. pyrazinamide
4. ethambutol or streptomycin
Definition
4 medications used to treat TB; all 4 for 1st 2 months, then 2* daily or twice weekly for 4 additional months
Term
hepatotoxicity - don't drink alcohol
Definition
important consideration for patients on TB medications
Term
COPD
Definition
a preventable, treatable, progressive disease that limits airflow in the lungs and may include extrapulmonary effects
Term
chronic bronchitis
Definition
characterized by a cough that occurs on most days at least 3 months a year for 2 consecutive years (inflammation, secretions, edema)
Term
emphysema
Definition
abnormal, permanent enlargement of terminal airspaces (distal to the terminal bronchioles); destruction of alveolar walls
Term
blue bloater
Definition
name to describe pt with chronic bronchitis
Term
pink puffer
Definition
name to describe pt with emphysema
Term
forced vital capacity (FVC)
Definition
maximum exhalation after maximum inspiration
Term
forced expiratory volume (FEV)
Definition
volume forcibly exhaled during 1st second (usually 75-80% of FVC)
Term
residual volume
Definition
volume remaining in the lungs after maximum exhalation
Term
total lung capacity
Definition
volume of air in the lungs after maximum inspiration
Term
spirometry
Definition
increased residual volume and total lung capacity due to hyperinflation
Term
pulmonary function test
Definition
measures lung volume and air flow & used to diagnose pulmonary disease
Term
smoking cessation
Definition
number 1 priority of COPD treatment/management
Term
bronchodilators
Definition
selectively activate beta2-adrenergic receptors to relax smooth muscle of lungs
Term
anticholinergics
Definition
block acetylcholine at muscarinic receptros
Term
ways to manage COPD exacerbation
Definition
1. supplemental O2
2. bronchodilators
3. add glucocorticoids
4. antibiotics
5. noninvasive positive pressure ventilation
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