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Regulation and Homeostasis through the actions of Hormones |
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Peptides, Steroids and Amines |
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defining hormone and their actions |
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Definition
defined by structured tissue that secrete them. Secreted by ductless glands, Hormones act locally (act on cells adjacent to where the hormone is synthesized or secreted) or are carried by the vascular system to other tissues of the body. Ovary: responds to hormone but its not considered a gland. |
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neurotransmitters having an endocrine (like function) action -don’t confuse hormones with neurotransmitters |
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Similar to ADH and stored in the nerve terminals and are release by action potentials |
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Act on other neurons whose neurotransmitters have a systemic effect |
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-synthesize and secrete -turn on gene expression -turn on and turn off enzymes -affect protein syntheses and transport capacity |
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Peptides and Small Proteins |
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Neuro-secretions, Hormones of the Anterior and Posterior Pituitary Glands, Hormones of the Pancreas and Para-follicular cells of the Thyroid Gland. |
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all synthesized from the amino acid tyrosine |
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synthesized and secreted from the Thyroid Gland, and Epinephrine and Norepinephrine from the Adrenal Medulla. |
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Hormones synthesized from cholesterol. |
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Calcitriol important in mediating abortion of dietary calcium and re-absorption form the kidney and co-factor in mobilizing calcium stored in bones |
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Regulation blood Glucose, is the only hormone that can act on amino acids, stimulating the conversion of AA into glucose. All other pathways are associated with breaking down molecules build from glucose. |
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water balance through regulation renal Na Reabsorption and Secretion |
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Progesterone, Estrogens & Testosterone |
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Sex Steroids, responsible for female synthesizing of progesterone |
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Progesterone & Estrogen + their precursors |
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Testerosterone + its precursors + products of testosterone metabolism. -Ability to metabolize testosterone in critical in development of male fetal development. |
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Action of Neurocrines and Hormones |
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Definition
•bind specific membrane or intracellular receptor •stimulating the synthesis and release of intracellular signaling molecules •either activate or inactivate enzyme system or initiate transcription within DNA for protein |
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