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NPB MT4
Renal-Repro
57
Physiology
Undergraduate 4
02/25/2011

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Cards

Term
what does the renal system homeostatically regulate? (6)
Definition

1) water content

2) arterial pressure

3) ion levels

4) body pH

5) toxin levels

6) synthesis of red blood cells

Term
is the body an open or closed system? 3 pathways out?
Definition

closed.

1) lungs

2) GI system

3) renal system

Term
main role of kidneys
Definition
form urine
Term
nephron: how is blood involved?
Definition
allows us to make concentrated or dilute urine. capillary blood NEVER enters. we form filtrate extracted from the blood.
Term
blood filtration rate
Definition
125 mL/minute
Term
how much blood do we have in our body at a time?
Definition
~5L
Term
proximal convoluted tubule
Definition
reabsorbs 66% NaCl, 60% of H2O, 100% glucose
Term
diabetes mellitus
Definition
when PCT can't reabsorb all the filtered glucose
Term
loop of henle. difference between ascending and descending?
Definition

absorbs H2O and NaCl

Descending: H2O via osmosis

Ascending: NaCl via active transport

Term
ascending loop of henle
Definition
impermeable to H2O, actively transports Na+, contributes to osmodic gradient
Term
what affects the distal convoluted tubule and collecting duct?
Definition
hormones
Term
anti-diruetic hormone (ADH), where is it produced? what does it do?
Definition
produced by posterior pituitary gland, allows us to produce very concetrated urine. promotes water absorption by DCT and collecting duct.
Term
affects of caffeine and alcohol
Definition
inhibits effects of ADH, encourages production of urine
Term
aldosterone. role of jextaglomenclar apparatus
Definition
released in response to decrease in blood volume. produced by adrenal glands. blood volume is monitored by JGA.
Term
how JGA works to release aldosterone
Definition
JGA releases renin, which cuts angiotensinogen. this becomes angiotensin I, then angiotensin II, this stimulates adrenal glands, which releases aldosterone
Term
3 roles of reproductive system
Definition

1) produces gametes (sperm and ova)

2) contributes to genetic diversity

3) recreation

Term
asexual reproduction
Definition
individual produces clones, low genetic diversity
Term
haploid cells vs diploid cells
Definition

haploid: 23 chromosomes

diploid: 46 chromosomes

Term
meiosis. difference between males and females?
Definition

production of gametes (sperm and ova)

females: produce few high quality ova

males: produce many high quality sperm

Term
gonads. name in M and F?
Definition
gamete producing parts (testes and ovaries)
Term
role of y chromosome
Definition
give "maleness" (encodes TDF). shows itself at around 7 weeks of fetal development
Term
seminal vesicles
Definition
secretion, high in fructose and prostaglandins
Term
epididymis
Definition
storage and maturation of sperm
Term
prostate gland
Definition
basic (in pH) secretion
Term
bulbourethral gland
Definition
secretes mucus for lubrication
Term
how much sperm created per day? how much released in one ejaculation?
Definition
100 million, 300 million
Term
ovary
Definition
site of oogenesis, produces gametes, estrogen, and progesterone
Term
oviduct
Definition
fallopian tube - where fertilization takes place
Term
# of eggs in developing fetus, following birth, puberty, and lifetime
Definition

6-7 million

1 million

300K

400 ovulated

Term
atresia
Definition
death of oocytes (99.97% over lifetime)
Term
3 layers of uterus
Definition
peri, myo, endometrium (In to out)
Term
how long do ovum live?
Definition
about 24 hours
Term
how long sperm can survive in female reproductive system
Definition
4 days
Term
corpus luteum
Definition
secretes estrogen and progesterone
Term
what triggers ovulation?
Definition
surge of lutenizing hormone (LH)
Term
zygote
Definition
when sperm and egg meet (fertilization of ovum)
Term
role of human chronic gonadotropin (HCG)
Definition
maintains endometrium lining (1-3 months)
Term
how do pregnancy tests work?
Definition
detects levels of HCG in blood or urine
Term
2 main roles of immune system
Definition
protects body from invaders (bacteria, virus, worms, pollen) and from cells that go bad (cancerous)
Term
innate immune response
Definition
autonomical, quick-acting
Term
adaptive immune response
Definition
antibodies (immunized)
Term
leukocytes
Definition
white blood cells
Term
neutrophils
Definition
phagocytotic (50-60% of cells)
Term
eosinophil
Definition
worms, chemicals (cytokinesis - inflammatory) 1-2% of cells
Term
basophils
Definition
rare .5% release histamine and heparin (helps with blood viscosity)
Term
monocyte
Definition
immature form. migrates to other tissues (macrophage), phagocyte
Term
lymphocytes
Definition
adaptive immune response. produces antibodies. stores "memories" of invaders.
Term
antigen
Definition
target of immune system
Term
lymphocyte: 2 responses
Definition

antibody-mediated (b-cells)

cell-mediated (thymus)

Term
4 jobs of antibody
Definition

1) mark an invader

2) turn on complement system

3) bacteria clumps in presence of AB (inhibits bacterial growth)

4) specific AB acts as a receptor

Term
antibody IgG
Definition
secreted in plasma of blood
Term
antibody IgM
Definition
membrane receptor
Term
antibody IgA
Definition
secreted in mucous membranes, urogenital tract, tears, and milk
Term
t-lymphocytes
Definition
controls the cell-mediated response, controls all immune responses
Term
cytotoxic t-cells
Definition
kill other cells, releases chemicals right next to cells (virus-infected cells and cancer cells)
Term
helper or regulating t-cells, 3 main roles
Definition

control all immune responses

1) enhance abilities of b-cells to secrete antibodies

2) release chemicals that attract immune cells to injury/infection site

3) releases chemicals involved in activation of t/b-cells

Term
suppressor t-cells, main role, consequence of failing?
Definition
in charge of shutting down immune responses, its failure to work could cause autoimmune diseases
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