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Nonrandom mating and inbreeding depression
Genomic frequencies
14
Biology
Undergraduate 1
04/30/2013

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Term
Non random mating
Definition
When mating is not random, it violates the Hardy Weinburg Principle and thus varies from the hardy weinburg equilibrium.
Term
Inbreeding
Definition
When mating idividuals are more closely realted than those drawn at random
Term
Outbreeding
Definition
When mating individuals are less closely related than those drawn at random.
Term

Change in allelic frequencies

 

Definition
Neither inbreeding or outbreeding cause changes in the allelic frequencies.
Term
Changes in genotypic frequencies
Definition
Both inbreedign and outbreeding do cause a change in genotypic frequencies.
Term
Genotypic frequency changes inbreeding vs outbreeding
Definition

UNder inbreeding the frequencies of the homozygotes increase while the heterozygotes decrease. 

 

Under outbreeding, the frequencies of the homozygotes decrease while the heterozygote increases. 

Term
Self-fertilization
Definition

THe mst extreme form of inbreeding, which occurs in many plants and only a few other organisms. 

 

Under self fertilization the heterozygotedcreases 50% in each generation. 

Term
Reestablish original genotypic frequencies
Definition
Since the underlying allelic frequencies do not change it only takes one generation of random mating to reestablish the original genotypic frequencies, even after 1,000 generations of self-fertilization.
Term
Inbreeding depression: the coupling of inbreeding and selection
Definition
Even though inbreeding by itself does not alter allelic frequencies in the population, the coupling of inbreeding and selection can significantly alter allelic frequencies, most typically throuh the phenomenon of inbreeding depression.
Term
Deleterious recessive alleles
Definition
Natural populaitons of most organisms (including humans) contain a significant number of deleterious recessive alleles.
Term
Effect of deleterious recessive alleles
Definition
The deleterious effects of these recessive alleles are masked in heterzygotes
Term
Inbreeding's efect on deleterious recessive alleles.
Definition
Since inbreeding results in an increase in the frequencies of homozygotes in the population, it means that a larger population will carry two copies of the deleterious allele causing the recessive trait to show more.
Term
Mortality rates
Definition
When large proportions of the offspring carry two copies of the deleterious allele, mortality rates tend to be higher.
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