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Noninfectious and Infectious Causes of Pregnancy Loss & Endo
Exam 2
40
Veterinary Medicine
Professional
10/06/2016

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Cards

Term
What are the common non-infecitous causes of pregnancy loss in mares?
Definition
-twin pregnancies
-uterine torsion
-umbilical cord compromise
-placental abnormalitis
-environmental factors
Term
Why do twin pregnancies cause abortion in mares?
Definition
-death of one or both twins from lack of placental nutrient exchange, common to occur around 9 months gestation
Term
What do we always check for with a mare with premature udder development?
Definition
-scanned transabdominally thoroughly looking for two heartbeats
Term
When during gestation do most uterine torsions occur? When are they identified?
Definition
-8-11 months gestation
-identified at time of foaling
Term
What are the clinical signs of uterine torsion?
Definition
-unresolving colic
-chronic low grade to moderate grade pain
Term
How do we diagnose uterine torsion?
Definition
-palpation per rectum: diagonally misdirected broad ligaments
Term
Which direction is most common with uterine torsions?
Definition
-counterclockwise
Term
What is the normal length of an equine umbilical cord?
Definition
-36-83 cm
Term
What can go wrong regarding the umbilical cord?
Definition
-vascular occlusion: fetus can have distended abdomen or elongated naval stalk, vascular wall tears or hemorrhages in cord, local edema at amnion
-urachal obstruction: possible bladder rupture
Term
What is the cause abortion in the case of body pregnancies?
Definition
-lack of nutrient exchagne
Term
What is the cause of hydrops allantois?
Definition
-fetal membrane abnormality
Term
What issues do spiny caterpillars cause? Expound.
Definition
-mare reproductive loss syndrome
-flocculent material in fetal fluids
0inflammation of umbilical cord and amnion, pneumonia, fetal septicemia
Term
What repro issues does fescue toxicosis cause in the mare?
Definition
-prolonged gestation lengths
-thickened placentas
-weak and dysmature foals
-agalactia
-foal and mare mortality
-separation of chorion from endometrium during last 6 months
-inc early embryonic death
Term
What are the possible bacterial causes of pregnancy loss in horses?
Definition
-Strep zooepidemicus
-E. coli
-P. aeruginosa
-Nocardioform
Term
Where is nocardioform identified?
Definition
-base of pregnant horn
Term
How do bacteria cause pregnancy loss?
Definition
-leads to placentitis and subsequent pregnancy loss and septic foal
Term
What is ascending placentitis? HOw do mares present? When during gestatin does it occur?
Definition
-site of bacterial inoculation occurs through vulva and at level of cervix
-mares present with premature udder development and/or vaginal discharge
-b/n 5-10m
Term
How do we diagnose ascending placentitis?
Definition
-transrectal US via CTUP
Term
Definition: Placentitis
Definition
-inflammation of the chorioallantois
Term
What causes horn base placentitis?
Definition
-NOcardiofrom
Term
How do we treat placentitis?
Definition
-broad spectrum antibiotics, anti-inflamamtories, tocolytic drugs (dec uterine contractions resulting from inflammation)
Term
What are the two major fungal causes of pregnancy loss in the mare?
Definition
-EHV-1
-EVA
Term
What are the fungal causes of pregnancy loss in the mare?
Definition
-Aspergillus fumigatus
-Mucor sp
-foal receives inadequate nutrition
-organism may eventually infect the fetus, causing lesions on the liver and lungs
Term
How is EHV-1 transmitteD?
Definition
-respiratory route, aborted fetuses or fluids
Term
What is the incubation of EHV-1?
Definition
-2-12 weeks
Term
How does EHV-1 cause abortion?
Definition
-transplacental transmission during the final trimester of pregnancy
-endometrial vascular damage: thrombosis
Term
What happens if a pregnant mare is infected with EHV-1 close to term?
Definition
-diseased and compromised foal may be born with viral pneumonitis
Term
How is eVA transmitted?
Definition
-resp route or venereal route (stallions can be carriers!)
Term
How does EVA symptomatically differ from EHV-1?
Definition
-mare gets symptoms before aboriton
Term
What are the pre-abortion symptoms in the mare with EVA?
Definition
-fever, limb edema, conjunctivitis, diarrhea, serous nasal discharge
Term
How is EVA distributed in the body?
Definition
-distributed to vascular endothelium and myocytes of blood vessels
Term
When does abortion occur in the mare with eVA?
Definition
-within 2-14 days of onset
Term
When during gestation does the greatest EVA abortions occur?
Definition
-5-10 months
Term
How do we diagnose uterine infections?
Definition
-cytology brush/swab and culture
Term
What causes bacterial endometritis?
Definition
-failure of uterine defence mechanisms
-failure of vulva, vestibule, cervix
-breeding is a source of uterine contamination
Term
What are some of the etiologies behind bacterial endometritis?
Definition
-beta-hemolytic Streps
--E. coli
-Staph
-Klebsiella
-Pseudomonas
-Corynebacteria
-T. equigenitallis
Term
What is special about T. equigenitalis as an agent of Contagious Equine Metritis? How is it transmitted? Clinical signs?
Definition
-highly resistant
-venerally transmitted
-endometritis, vaginal discharge, devastating effect on fertility
Term
Do outbreaks or individual cases tend to occur with Contagious Equine Metritis due to T. equigenitalis?
Definition
-outbreaks
Term
What may lead to fungal endometritis? What is seen on endometrial cytology?
Definition
-history of repeated antibiotic usage
-active or chronic-active inflammatory pattern
-candida, mucor, aspergillis, etc
Term
HOw do we treat endometritis?
Definition
-uterine lavage until fluid is clear
-Intrauterine antibiotics: induction of drug resistance, secondary bacterial or yeast oergorwth, lcoally irritating
-Systemic: ease of administration, may be decreased expense
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