Term 
         | 
        
        
        Definition 
        
        | Proportion of + screens among those known to have the condition of interest. |  
          | 
        
        
         | 
        
        
        Term 
         | 
        
        
        Definition 
        
        | Proportion of negative screens among those known not to have the condition |  
          | 
        
        
         | 
        
        
        Term 
        
        | Positive predictive value |  
          | 
        
        
        Definition 
        
        | True positives among all positive screens |  
          | 
        
        
         | 
        
        
        Term 
        
        | Negative predictive value |  
          | 
        
        
        Definition 
        
        | Tue negative among those with negative screens |  
          | 
        
        
         | 
        
        
        Term 
        
        | Absolute risk vs relative risk |  
          | 
        
        
        Definition 
        
        Absolute risk=probability that an event will occur (rate of uterine rupture for VBAC pt is 2 per 1000 or 0.2%) Relative risk=estimate of the probability of an adverse event in one group relative to another group. I.e. Risk of rupture after csection is 2/1000 vs .06 per 1000 without prior csection - increase of 37 fold |  
          | 
        
        
         | 
        
        
        Term 
        
        | How use of both absolute and relative risk can influence woman's perception of risk |  
          | 
        
        
        Definition 
        
        | Telling a women her risk of uterine rupture is increased 37 fold is much different than saying that her risk is less than 1% (0.2%).  Health care providers can convey their own perceptions in how they present risk |  
          | 
        
        
         | 
        
        
        Term 
         | 
        
        
        Definition 
        
        | This term refers to communication patterns about medical risk that are biased to influence women's decisions. Example: woman is given handout about quad screen, told this is done at 16weeks and told to ask care provider any questions. This is informed compliance not informed consent |  
          | 
        
        
         | 
        
        
        Term 
         | 
        
        
        Definition 
        
        | How provider gives info can be framed toward offering a superior choice over another to avoid perceived risks. Example: pt is told her baby is "big" and is offered an induction to avoid problems related to suspected macrosomia. Possible fetal risks are not quantified and risks of labor induction are not discussed, nor is the possibility that no harm may occur by waiting |  
          | 
        
        
         | 
        
        
        Term 
        
        | Concept of language as "control" |  
          | 
        
        
        Definition 
        
        Shifts focus from woman Pregnancy as a diagnosis- confirmed by professional not woman Seeing fetus on US:separation Labor as diagnosis "false labor vs real labor" Rushed delivery of placenta Presenting the baby to mom |  
          | 
        
        
         | 
        
        
        Term 
         | 
        
        
        Definition 
        
        See: positive and negative predictive values
  Predictive values are very dependent on the prevalence of the condition in the population being screened |  
          | 
        
        
         | 
        
        
        Term 
        
        | Calculate gravida and para using 5 digit system |  
          | 
        
        
        Definition 
        
        Gravida=number of pregnancies Para=births over 20 weeks, multiples are counted as one birth event Term Preterm Abortion (spontaneous or induced less than 20weeks) Living children |  
          | 
        
        
         | 
        
        
        Term 
        
        | Contraindications to exercise in pregnancy |  
          | 
        
        
        Definition 
        
        Absolute contraindications according to ACOG Hemodynamically significant heart disease Restrictive lung disease Incompetent cervix Multiple gestation  Premature labor in present pregnancy Ruptured membranes Preeclampsia or PIH Persistent second or third trimester bleeding Placenta previa |  
          | 
        
        
         | 
        
        
        Term 
        
        | Immunizations to avoid in pregnancy |  
          | 
        
        
        Definition 
        
        HPV- finish series after pregnancy if already started LAIV- live attenuated inhaled influenza vaccine MMR- live virus vaccine Varicella- live attenuated Zoster- live attenuated BCG-not enough studies |  
          | 
        
        
         | 
        
        
        Term 
        
        | Vaccines that are recommended in pregnancy |  
          | 
        
        
        Definition 
        
        Hep A- if otherwise indicated only Hep B- in some circumstances  Influenza- *recommended for all preg women in flu season Td- if otherwise indicated. If not previously vaccinated she will need a 3 dose series with one of the shots replaced with Tdap in the 27-36 week time frame Tdap- recommended once each pregnancy between 27-36 weeks regardless of history of receiving Tdap Meningococcal- ok if otherwise indicated Polio- ok if needed only Anthrax- only if high risk of exposure. Not recommended if Low-risk of exposure Rabies- ok if otherwise indicated Smallpox- recommended post-exposure only. Pre-exposure not recommended Yellow fever- May be used if benefit outweighs risk |  
          | 
        
        
         | 
        
        
        Term 
        
        | Other vaccines: inadequate data |  
          | 
        
        
        Definition 
        
        | Inadequate data exists for PCV13, PPSV23, Japanese encephalitis, typhoid |  
          | 
        
        
         | 
        
        
        Term 
        
        | When is Hep B vaccine recommended in pregnancy? |  
          | 
        
        
        Definition 
        
        | Hep b vaccine is recommended for women identified as being at risk for HBV infection in pregnancy- more than one sex partner in past 6 months, evaluated or treated for std, recent or current IV drug use, or HBsAg positive sexual partner. |  
          | 
        
        
         | 
        
        
        Term 
        
        | Components of first prenatal visit: history and screenings |  
          | 
        
        
        Definition 
        
        Begin to establish relationship with woman 
Comprehensive health history: primary care, medical and surgical, family history, family and personal genetic history for both partners, menstrual, obstetric and gyn histories, sexual history, history of contraceptive use and safety.  
Depression screening and intimate partner violence screeening, immunization screening 
Risk history- substance abuse, environmental exposures, other potential harms 
Also: symptoms of pregnancy, women's concerns, acceptance of pregnancy  
   |  
          | 
        
        
         | 
        
        
        Term 
        
        | First Prenantal Visit- Education and Guidance |  
          | 
        
        
        Definition 
        
        Topics- stopping all harmful substances (tobacco, alcohol, drugs, teratogens such as medications and occupational exposures) 
Seatbelt use, travel, dental care, employment or education plans, appropriate exercise and activity, hot tub/sauna use, nutrition, vaccines, over-the-counter meds. 
Anticipatory guidance: fetal growth, common discomforts, pregnancy related changes with related appropriate treatments, mood changes.  
Orientation to midwifery care, schedule of visits, when to call midwife, food safety, options for genetic/chromosomal anomaly screening, toxoplasmosis, sexuality, myths/superstitions, breast support, establishing EDD, weight gain guidelines, pica, perineal and vaginal care  
   |  
          | 
        
        
         | 
        
        
        Term 
        
        | First Prenatal Visit- Physical exam components |  
          | 
        
        
        Definition 
        
        Height and weight 
Vital signs 
Complete physical with pelvic exam and clinical pelvimetry 
Assessent of uterine size/gestational age/compare with LMP  |  
          | 
        
        
         | 
        
        
        Term 
        
        | Relevant history, physical, lab and risk assessment data for each trimester: First trimester |  
          | 
        
        
        Definition 
        
        Labs: Review results for initial visit (blood type, antibody screen, RH. hbg/hct or CBC to include PLC, HepBsAg, chlamydia with or without gonorrhea, syphilis (rpr/vdrl), rubella titer, pap, UA and culture, offer cystic fibrosis testing-- possibly lead level, hemoglobin electrophoresis, diabetes screening, free beta hCG). 
  
?nuchal tranlucency, PAPP-A, free beta hCG, CVS 
  
Physical: weight, blood pressure, fhr with doppler after 8 weeks, assess uterine size and change from previous visit 
  
Screenings: Interval history, risk assessment, woman's concerns. Review medications, any symptoms, travel...  
  
   |  
          | 
        
        
         | 
        
        
        Term 
        
        | Relevant history, physical, lab and risk assessment data for each trimester: Second trimester |  
          | 
        
        
        Definition 
        
        Labs: Follow-up on previous results, amniocentesis after 15 weeks if indicated, Quad screening or multiple markers (15-20weeks), Anatomy US (18-20weeks).  
  
Physical: weight, blood pressure, Abdominal exam (fundus halfway to umbilicus at 16 weeks, 2 fungerbreaths below umbilicus at 18 weeks, immediately below umbilicus at 20 weeks, over 20 weeks fundaus should equal weeks gestation +/- 2-3cm). FHR with doppler. 
  
Screenings: Risk assessment, woman's symptoms and concerns need to add specifics re:risk assesment for each trimester  |  
          | 
        
        
         | 
        
        
        Term 
        
        | Relevant history, physical, lab and risk assessment data for each trimester: Third trimester |  
          | 
        
        
        Definition 
        
        Labs: Gest diabetes screening (24-28weeks), hbg/hct 28weeks, ?repeat antibody screen if Rh negative- prepare to give Rhogam. Follow up on prev. results. ? repeat STI testing as per state law or history. Group B test at 35-37weeks unless unnessary based on history).  
  
Physical: Weight, blood pressure, OB Abd. exam (fundal height), fetal lie and presentation, Leopolds 35-40 weeks for fetal lie, presentation, position, variety, and EFW. FHR. SVE for bishop score if over 40 weeks. AFI, nonstress test, BPP over 40weeks if indicated 
  
Screenings: Risk, woman's concerns. Fetal kick counts if high-risk at 28 weeks/start at 35 weeks for all/ Depression screen, intimate partner violence screen.   |  
          | 
        
        
         | 
        
        
        Term 
        
        | Benefits of exercise in pregnancy |  
          | 
        
        
        Definition 
        
        increased energy 
Improved sleep 
help with weight control 
increased strength and endurance 
greater sense of wellbeing 
fewer back aches 
decreased risk of pre-e 
possible decreased risk for gest diabetes 
may help control blood sugar in combination with diet for women with gest diabetes when diet alone if ineffective.
p>?may have significantly shorter second stage of labor but no overall decrease in labor length has been found 
Contradictary evidence re: exercise and vag vs csection and exercise effect on prenatal weight gain  |  
          | 
        
        
         | 
        
        
        Term 
        
        Anticipatory Guidence:Exercise in Pregnancy 
   |  
          | 
        
        
        Definition 
        
        Women may start or maintain exercise programs at moderate or vigorous intensities in preg without adverse fetal effects. Use talk test to determine intensityp>
   
Women who are sedentary will benefit from adding exercise to their routines. Advising an increase in activity via daily walking, pregnancy exercise class etc is part of optimal prenatal care. Pregnancy can be a major motivator to make positive health changes  
30 minutes daily of
Moderate activity equivalent to brisk walking is recommended |  
          | 
        
        
         | 
        
        
        Term 
        
        | Physiologic changes of pregnancy that impact exercise ability/tolerance |  
          | 
        
        
        Definition 
        
        Women will feel short of breath sooner in pregnancy- due to progesterone effects. Reassure that this is normal  
  
Advise warm up and cool down periods with each exercise session-- musculoskeletal changes may predipose women to injury 
  
Avoid supine positions sexism and third trimesters. Pregnancy does not increase risk of hyperthermia with exercise
Avoid activities that have high potential for and trauma, falling, twisting of joints suddenly. Nausea, wt gain and fatigue may cause women to need to change expectations re: exercise
p>add more here? |  
          | 
        
        
         | 
        
        
        Term 
        
        | More commonly used medication in pregnancy that appear to be safe: GI issues |  
          | 
        
        
        Definition 
        
        N/V- antihistamines (Benadryl, doxylamine (unisom), doxylamine/pyridoxine (Diclegis). Phenothiazines (compazine, phenergan). Benzamides (Metoclopramide- Reglan), Serotonin agonists (Ondansetron).  
  
Acid reflux- antacids- Aluminum/mag hydroxide (rolaids, maalox) and calcium carb (tums). These agents are preferred. 
  
Mucosal protectants- Sucralfate (Carafate) 
  
H2 antagonists (Cimetidine (tagamet), famotidine (pepcid), nizatidine (axid), ranitidine (zantac). Zantac is preferred agent 
  
PPIs-esomeprazole (nexium), omeprazole (prilosec, lansoprazole (prevacid), pantaprazole (protonix), rabeprazole (aciphex): increased risk of hypospadias has been reported  |  
          | 
        
        
         | 
        
        
        Term 
        
        | More commonly used medication in pregnancy that appear to be safe: diarrhea/constipation |  
          | 
        
        
        Definition 
        
        Diarrhea: Antidiarrheals: Alosetron (lotronex), diphenoxylate/atropine (lomotil), loperamide (imodium). Alosetron only for IBS-related diarrhea who have failed conventional treatment 
  
Constipation: osmotic laxatives: lactulose (Enulose), Mag citrate (Citroma), PEG (MiraLax) 
Stimulant laxatives- Bisacodyl (Correctol), Senna-- for short term use only for these agents 
Stool softener- Docusate- Colace (short term also)  |  
          | 
        
        
         | 
        
        
        Term 
        
        | Medications to avoid in pregnancy |  
          | 
        
        
        Definition 
        
        MEDS to AVOID in pregnancy: Caution esp in first trimester when organogenesis occurs 
From Pharmacolgy for Women’s Health 1047-1048 
Warfarin 
Isotretinion 
Valporic acid 
Tetracycline 
Lithium 
DES 
Biazin 
Erythromycin estolate (Ilosom) 
Ergot alkaloids (abortifacients) 
Aminoglycosides 
Amiodarone 
Androgenis steroids 
ACE Inhibitors 
ARBs 
Antithyroid drugs 
SSRI- Paxil 
Statins 
Benzodiazepines 
Tegretol 
Aspirin- low doses (81mg/daily) appear to be ok- higher doses may cause prolonged gestation, prolonged labor, bleeding probs in neonate, IUGR, perinatal mortality 
Iodine 
Lindane (Kwell) 
Methotrexate 
Misoprostol (unless used to induce labor/ripen cervix as off label use) 
Mifepristone 
Dilantin 
Cyclophosphamide 
NSAIDs- AVOID ESP first and third trimesters 
(increase risk of miscarriage, also risk of premature closure of ductus arteriosus esp third trimester, fetal renal toxicity, inhibition of labor) 
Magnesium trisilicate (gaviscon): increase risk of fetal nephrolithiasis. 
Sodium bicarb (Neut): metabolic acidosis and fluid overload 
Bismuth subsalicylate (peptobismol, kaopectate): salicylate moiety can cause increased perinatal mortality 
Thalidomide 
Valproic acid 
Vitamin A- over 8000IU/day. deficiencies may also cause malformations 
 
  |  
          | 
        
        
         | 
        
        
        Term 
        
        | Centering Pregnancy: theorectical basis, how it works, how this empowers women. Also benefits and limitations |  
          | 
        
        
        Definition 
        
        Theorectical basis: based on feminist theory, midwifery model of care, social support theory, adult learnign theory and social cognitive theory 
  
Comprehensive care in a group setting. melds midwifery philosophy of care with empowering women 
  
How it works: takes advantage of fact that women in preg are open to learning and want to share concerns, reactions and experiences. involves self-care activities, faciliator leadership style, includes overall plan and core content each session, stables group composition, provides social opportunity, ongoing eval of outcomes. 10 2-hour sessions, similar due dates. includes education and prenatal care. includes focused physical assessment by provider, group size 8-12 women, meet in a circle. family involvement optional. meet monthly than every 2 weeks and then weekly as per traditional prenatal schedule 
  
How this empowers women: shift in relationship so that women take on the decision-making power re:topics discussed and for self-care. individual contribution of each memeber is valued. self-care activities (wt, bp, self-assessment of learning needs). consumer as equal partner. Woman as expert on her own needs 
  
Benefits: increased attendance at care, increased preg-related knowledge and increase satisfaction with care. builds community, increased birth weights for infants 
Limitatons: resistance to change, need to recruit women, changes scheduling for careproviders/women  |  
          | 
        
        
         | 
        
        
        Term 
        
        | More commonly used medications in pregnancy that are safe |  
          | 
        
        
        Definition 
        
        Tylenol, opiates, flexeril 
analgesic creams- mentholated or capsacin 
  
Allergies and colds: frist generation antihistamines: Chlorpheniramine (Chlortrimeton) first choice; also benadryl, triprolidine, doxylamine. Zyrtec most studied second generation.  
Oral decongestants: pseudoephedrine ok after first trimester (increase risk of gastroschisis in first tri) 
Nasal decongestants: Afrin, phenylephrine, xylometazoline all ok. Saline nasal spray ok 
  
Nasal corticosteriods- budesomide, becamethasome, and intranasal cromolyn sodium  
  
Antibiotics: PCN, EES, Augmentin, amox, cefizol, ceftin. Zithromax, macrobid, rocephine, third generation cephalosporin + macrolide for pneumonia 
  
Antifungals- topical for yeast=butoconazol, clotrimazole, miconazole, terconazole, nystatin, Avoid diflucan in firt trimester. Metronidazole (flagyl) ok.  
  
Dental care: lidocaine and xylocaine ok, xrays ok (would need 5000 dental xrays to exceed safe radiation dose), PCN, augmentin, amox, cleocin all ok.   |  
          | 
        
        
         | 
        
        
        Term 
         | 
        
        
        Definition 
        
        3-4 weeks 150-1000mIU/mL US: decidual thickening 4-5weeks >1000-2000mIU/mL US: gest sac visible tvus at 1000 5-6weeks 1000-7200mIU/mL, yolk sac present when gest sac >10mm. Embryo present if gets sac> 18mm. Cardiac activity present when crown rump >5mm 6-7weeks >10,800mIU/mL; crown rump 4-9mm |  
          | 
        
        
         | 
        
        
        Term 
        
        | Presumptive signs of pregnancy |  
          | 
        
        
        Definition 
        
        Woman experience/reports: N/V Cessation of menses in women with prev regular cycles Tingling, tightness, increased nodularity +\- enlargement of breast or nipples Urinary frequency Fatigue Sustained increased basal body temp  Skin pigment changes |  
          | 
        
        
         | 
        
        
        Term 
        
        | Probable signs of pregnancy |  
          | 
        
        
        Definition 
        
        Physical exam or lab test: Breast changes- colostrum, enlargement of breasts/nipples  Skin changes- striae, chloasma, linea nigera  Enlarges abdomen, enlarged uterus  Palpable fetal outline Ballottement  Piskacek's sign Hegar, goodell, Chadwick signs Palpation of Braxton hicks Positive preg test Positive fetal movement- palpable |  
          | 
        
        
         | 
        
        
        Term 
        
        | Positive signs of pregnancy |  
          | 
        
        
        Definition 
        
        Sonogram Audible fetal heart rate |  
          | 
        
        
         | 
        
        
        Term 
         | 
        
        
        Definition 
        
        Detectable at 8-10 days after ovulation- coincides with implantation of fertilized egg. Doubles every 48-72 hours in 85% of normal preg and continues to do so until peak at 100,000 mIU/mL then slowly decrease to stable level of 20,000 Serial levels are useful but 48hours may not be enough to see doubling due to individual differences |  
          | 
        
        
         |