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Neuroscience Terms (Chap 13 and on)
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119
Biology
Undergraduate 1
03/31/2010

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Term
Smooth Muscle
Definition
A type of muscle in the digestive tract, arteries, and related structures; innervated by the autonomic nervous system and not under voluntary control
Term
striated muscle
Definition
A type of muscle with a striated, or striped, appearance; the two types are skeletal and cardiac.
Term
cardiac muscle
Definition
A type of striated muscles found only in the heart; it contracts rhythmically even in the absence of innervation.
Term
skeletal muscle
Definition
A type of striated muscle that is under voluntary control and that functions to move bones around joints; derived from mesodermal somites.
Term
muscle fibers
Definition
A multinucleated skeletal muscle cell.
Term
Somatic motor system
Definition
The skeletal muscles and the parts of the nervous system that control them; the system that generate behavior
Term
flexion
Definition
The direction of movement that closes a joint
Term
extension
Definition
The direction of movement that opens a joint
Term
flexors
Definition
A muscle that causes flexion when it contracts
Term
synergist muscle
Definition
A muscle that contracts with other muscles to produce movement
Term
antagonist
Definition
A muscle that acts against another at the same joint.
Term
axial muscles
Definition
A muscle that controls movements of the trunk of the body
Term
proximal (girdle) muscles
Definition
A muscle that controls the shoulder or pelvis
Term
distal muscles
Definition
A muscle that controls the hands, feet, or digits
Term
Alpha motor neurons
Definition
a neuron that innervates the extrafusal fibers of skeletal muscle
Term
motor unit
Definition
One alpha motor neuron and all the skeletal muscle fibers it innervates.
Term
motor neuron pool
Definition
All the alpha motor neurons innervating the fibers of a single skeletal muscle
Term
fast motor units
Definition
A motor unit with a large alpha motor neuron innervating rapidly contracting and rapidly fatiguing white muscle fibers.
Term
slow motor units
Definition
A motor unit with a small alpha motor neuron innervating slowly fatiguing red muscle fibers
Term
excitation-contraction coupling
Definition
The physiological process by which the excitation of a muscle cell leads to its contraction.
Term
sarcolemma
Definition
The outer cell membrane of a skeletal muscle fiber
Term
myofibril
Definition
A cylindrical structure within a skeletal muscle fiber that contracts in response to an action potential
Term
sarcoplasmic reticulum (SR)
Definition
An organelle within a skeletal muscle fiber that stores Ca2+ and releases it when stimulated by an action potential in T tubules
Term
T tubule
Definition
A membrane-enclosed tunnel running within a skeletal muscle fiber that links excitation of the sarcolemma with the release of Ca2+ from the sarcoplasmic reticulum
Term
Z lines
Definition
A band delineating sarcomeres in a myofibril of a muscle fiber
Term
sarcomere
Definition
The contractile element between Z lines in a myofibril; contains the thick and thin filaments that slide along one another to cause muscle contraction
Term
thin filament
Definition
A part of the cytoskeleton of a muscle cell containing actin, anchored to Z lines and sliding along thick filaments to cause muscle contraction
Term
thick filament
Definition
A part of the cytoskeleton of a muscle cell containing myosin, lying between and among thin filaments and sliding along them to cause muscle contraction
Term
myosin
Definition
A cytoskeletal protein in all cells and the major thick filament protein in a skeletal muscle fiber; causes muscle contraction by chemical interaction with actin
Term
actin
Definition
A cytoskeletal protein in all cells and the major thin filament protein in a skeletal muscle fiber; causes muscle contraction by specific chemical interactions with myosin.
Term
troponin
Definition
A protein that binds Ca2+ in a skeletal muscle cell, thereby regulating the interaction of myosin and actin.
Term
muscle spindle
Definition
A specialized structure within skeletal muscles that senses muscle length; provides sensory information to neurons in the spinal cord via group Ia axons; also called the stretch receptor
Term
proprioceptor
Definition
A sensory receptor from the muscles, joints, and skin that contributes to proprioception
Term
myotatic reflex
Definition
A reflex that leads to muscle contraction in response to muscle stretch, mediated by the monosynaptic connection between group Ia axons from a muscle spindle and an alpha motor neuron innervating the same muscle; also called the stretch reflex.
Term
intrafusal fibers
Definition
A specialized muscle fiber within a muscle spindle that receives motor innervation from gamma motor neurons
Term
extrafual fibers
Definition
A muscle fiber in skeletal muscle that lies outside muscle spindles and receives innervation from alpha motor neurons.
Term
gamma motor neuron
Definition
A motor neuron that innervates intrafusal muscle fibers
Term
Golgi tendon organ
Definition
A specialized structure within the tendons of skeletal muscle the senses muscle tension
Term
reciprocal inhibition
Definition
The process whereby the contraction of one set of muscles is accompanied by the relaxation of antagonist muscles
Term
central pattern generator
Definition
A neural circuit that gives rise to rhythmic motor activity
Term
lateral pathway
Definition
Axons in the lateral column of the spinal cord that are involved in the control of voluntary movements of the distal musculature and are under direct cortical control. 
Term
ventromedial pathway
Definition
Axons in the ventromedial column of the spinal cord that are involved in the control of posture and locomotion and are under brain stem control.
Term
corticospinal tract
Definition
The tract that originates in the neocortex and terminates in the spinal cord; involved in the control of voluntary movement
Term
motor cortex
Definition
Cortical areas 4 and 6, which are directly involved in the control of voluntary movement
Term
pyramidal tract
Definition
A tract running along the ventral medulla that carries corticospinal axons
Term
rubrospinal tract
Definition
A tract originating in the red nucleus and terminating in the spinal cord; involved in the control of movement
Term
red nucleus
Definition
A cell group in the midbrain involved in the control of movement
Term
vestibulospinal tract
Definition
A tract originating in the vestibular nuclei of the medulla and terminating in the spinal cord; involved in the control of movement and posture
Term
tectospinal tract
Definition
A tract originating in the superior colliculus and terminating in the spinal cord; involved in the control of head and neck movements
Term
reticular formation
Definition
A region of the brain stem ventral to the cerebral aqeduct and fourth ventricle; involved in many functions, including the control of posture and locomotion.
Term
pontine reticulospinal tract
Definition
A tract originating in the pontine reticular formation and terminating in the spinal cord, involved in the control of movement.
Term
medullary reticulospinal tract
Definition
A tract originating in the medullary reticular formation and terminating in the spinal cord
Term
primary motor cortex (M1)
Definition
Brodmann's area 4, locatted on the precentral gyrus; the region of the cortex that, when weakly stimulated, elicits localized muscle contractions
Term
premotor area (PMA)
Definition
The lateral part of cortical area 6, involved in the control of voluntary movement
Term
supplementary motor are (SMA)
Definition
The medial part of cortical are 6; involved in the control of voluntary movement
Term
ventral lateral nucleus (VL)
Definition
A nucleus of the thalamus that relays information from the basal ganglia and cerebellum to the motor cortex.
Term
basal ganglia
Definition
A collection of associated cell groups in the basal forebrain, including the caudate nucleus, putamen, globus pallidus, and subthalamus.
Term
caudate nucleus
Definition
A part of the basal ganglia in the basal forebrain, involved in motor control.
Term
putamen
Definition
A part of the basal ganglia in the basal forebrain; involved in motor control.
Term
globus pallidus
Definition
A part of the basal ganglia in the basal forebrain; involved in motor control.
Term
subthalamic nucleus
Definition
A part of the basal ganglia in the basal forebrain
Term
substantia nigra
Definition
A cell group in the midbrain that uses dopamine as a neurotransmitter and innervates the striatum
Term
striatum
Definition
A collective term for the caudate nucleus and putamen; involved in the initiation of willed movements of the body; plays a role in procedural memory.
Term
Parkinson's disease
Definition
A movement disorder caused by damage to the substantia nigra, characterized by paucity of movement, difficulty in initiating willed movement, and resting tremor.
Term
Huntington's disease
Definition
A hereditary, progressive, inevitably fatal condition characterized by dyskinesias, dementia, and personality disorders; associated with profound degeneration  of neurons in the basal ganglia and cerebral cortex.
Term
ballism
Definition
A movement disorder caused by damage to the subthalamus, characterized by violent, flinging movements of the extremities.
Term
cerebellum
Definition
A structure derived from the rhombencephalon, attached to the brain stem at the pons; an important movement control center
Term
ataxia
Definition
Abnormally uncoordinated and inaccurate movements, often associated with cerebellar dysfunction
Term
vermis
Definition
The midline region of the cerebellum
Term
pontine nuclei
Definition
The clusters of neurons that relay information from the cerebral cortex to the cerebellar cortex.
Term
homeostasis
Definition
The balanced functioning of physiological processes and maintenance of an organism's internal environment within a narrow range
Term
periventricular zone
Definition
A hypothalamic region that lies most medially, bordering the third ventricle
Term
magnocellular neurosecretory cell
Definition
A large neuron of the periventricular and supraoptic nuclei of the hypothalamus that projects to the posterior pituitary and secrets oxytocin or vasopressin into the blood
Term
oxytocin
Definition
A small peptide hormone released from the posterior pituitary by magnocellular neurosecretory cells; stimulates uterine contractions and milk letdown from the mammary glands
Term
vasopressin
Definition
A small peptide hormone released from the posterior pituitary by magnocellular neurosecretory cells; promotes water retention and decreased urine production by the kidney; also called antidiuretic hormone (ADH).
Term
parvocellular neurosecretory cells
Definition
A small neuron of the medial and periventricular hypothalamus that secretes hypophysiotropic peptide hormones into the hypothalamo-pituitary portal circulation to stimulate or inhibit the release of hormones from the anterior pituitary
Term
hypophysiotropic hormone
Definition
A peptide hormone, such as corticotropin-releasing hormone or gonadotropi-releasing hormone, released into the blood by the parvocellular neurosecretory cells of the hypothalamus
Term
hypothalamo-pituitary portal circulation
Definition
A system of blood vessels that carries hypophysiotropic hormones from the hypothalamus to the anterior pituitary.
Term
adrenal cortex
Definition
The outer segment of the adrenal gland; releases cortisol when stimulated by the pituitary adrenocorticotropic hormone.
Term
adrenal medulla
Definition
The inner segment of the adrenal gland, innervated by preganglionic sympathetic fibers; releases epinephrine.
Term
cortisol
Definition
A steriod hormone released by the adrenal cortex; mobilizes energy reserves, suppresses the immune system, and has direct actions on some CNS neurons
Term
autonomic ganglia
Definition
Peripheral ganglia of the sympathetic and parasympathetic division of the autonomic nervous system
Term
postganglionic neurons
Definition
A peripheral neuron of the sympathetic and parasympathetic divisions of the ANS; its cell body lies in autonomic ganglia, and its axons terminate on peripheral organs and tissues. 
Term
preganglionic neurons
Definition
A neuron of the sympathetic and parasympathetic divisions of the autonomic nervous system; its cell body lies in the CNS and its axons extend peripherally to synapse on postganglionic neurons in the autonomic ganglia
Term
sympathetic chain
Definition
A series of interconnected sympathetic ganglia of the ANS, adjacent to the vertebral column, that receive input from preganglionic sympathetic fibers and project postganglionic fibers to target organs and tissues.
Term
enteric division
Definition
A division of the ANS that innervates the digestive organs; consists of the myenteric and submucous plexuses.
Term
nucleus of the solitary tract
Definition
A brain stem nucleus that receives sensory input and uses it to coordinate autonomic function via its outputs to other brain stem and forebrain nuclei and to the hypothalamus
Term
locus coeruleus
Definition
A small nucleus located bilaterally in the pons; using NE as their neurotransmitter, its neurons project widely on all levels of the CNS.
Term
raphe nuclei
Definition
Clusters of serotonergic neurons that lie along the midline of the brain stem from the midbrain to the medulla and project diffusely upon all levels of the CNS.
Term
basal forebrain complex
Definition
Several cholinergic nuclei of the telencephalon, including the medial septal nuclei and basal nucleus of Meynert.
Term
motivated behaviors
Definition
Behavior at is incited to achieve a goal
Term
gender identity
Definition
A person's perception of his or her maleness or femaleness.
Term
sex-determining region of the Y chromosome (SRY)
Definition
A gene on the Y chromosome that codes for testis-determining factor; essential for normal male development
Term
luteinizing hormone (LH)
Definition
A hormone secreted by the anterior pituitary; its diverse roles include the stimulation of testosterone production in males and the facilitation of follicle development and ovulation in females.
Term
follicle-stimulating hormone (FSH)
Definition
A hormone secreted by the anterior pituitary; its diverse roles include the growth of follicles in the ovaries and the maturation of sperm in the testes.
Term
gonadotropin-releasing hormone (GnRH)
Definition
A hypophysiotropic hormone secreted by the hypothalamus; regulates the release of LH and FSH
Term
estrous cycle
Definition
The female reproductive cycle in most nonprimate mammals in which there are periodic episodes of estrus, of "heat"
Term
polygyny
Definition
Mating behavior in which one male mates with more than one female
Term
polyandry
Definition
Mating behavior in which one female mates with more than one male
Term
sexual dimorphism
Definition
A sex-related difference in structure or behavior
Term
sexually dimorphic nucleus (SDN)
Definition
A neuron cluster in the preoptic area of the anterior hypothalamus that in rats is significantly larger in males than in females
Term
interstitial nuclei of the anterior hypothalamus (INAH)
Definition
Four neuron clusters in the preoptic area of the anterior hypothalamus in humans, some of which may be sexually dimorphic
Term
organizational effect
Definition
The ability of a hormone to influence the prenatal development of sex organs and the brain
Term
activational effect
Definition
The ability of a hormone to activate reproductive processes or behaviors in the mature organism.
Term
Affective neuroscience
Definition
The study of the neural basis of mood and emotion
Term
James-Lange Theory
Definition
A theory proposing that the subjective experience of emotion is a consequence of physiological changes in the body
Term
Cannon-Bard Theory
Definition
A theory of emotion proposing that emotional experience is independent of emotional expression and is determined by the pattern of thalamic activation
Term
unconscious emotion
Definition
The experience or expression of emotion in the absence of conscious awareness of the stimulus that evoked the emotion
Term
limbic lobe
Definition
The hippocampus and cortical areas bordering the brain stem in mammals, which Broca proposed as a distinct lobe of the brain
Term
Papez circuit
Definition
A circuit of structures interconnecting the hypothalamus and cortex, proposed by Papez to be an emotion system
Term
limbic system
Definition
A group of structures, including those in the limbic lobe and Papez circuit, that are anatomically interconnected and are probably involved in emotion, learning, and memory
Term
Kluver-Bucy syndrome
Definition
A constellation of symptoms resulting from bilateral temporal lobectomy in humans and monkeys that includes decreased fear and aggression (flattened emotions), the tendency to identify objects by oral examination rather than visual inspection, and altered sexual behavior
Term
Predatory aggression
Definition
Attack behavior, often with the goal of obtaining food, accompanied by few vocalizations and low ANS activity
Term
Affective aggression
Definition
A threatening or defensive form of aggression accompanied by vocalizations and a high level of ANS activity
Term
psychosurgery
Definition
Brain surgery used to treat mental or behavioral disorders
Term
sham rage
Definition
A display of great anger in a situation that would not normally cause anger; behavior produced by brain lesions
Term
medial forebrain bundle
Definition
A large bundle of axons coursing through the hypothalamus carrying efferents from the dopaminergic, noradrenergic, and serotonergic neurons in the brain stem and fibers interconnecting the hypothalamus, limbic structures, and midbrain tegmental area.
Term
dorsal longitudinal fasciculus 
Definition
A bundle of axons reciprocally connecting the hypothalamus and midbrain PAG
Term
periaqueductal gray matter (PAG)
Definition
A region surrounding the cerebral aqueduct in the core of the midbrain, with descending pathways that can inhibit the transmission of pain-causing signals.
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