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excitable cells within the nervous system, use their excitability as a means of communication |
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Non-excitable, support cells for the nervous system |
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Glial cells that perform all glial functions EXCEPT myelinating |
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Glial cell responsible for myelin coating within CNS |
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Glial cell responsible for myelin coating within PNS |
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Spaces between myelin sheaths on axon |
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Another name for the cell body of the neuron |
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branching, receptive portion of neuron |
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conducting element of neuron, up to 1 meter in length |
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projection off of the neuron cell body - either dendrite or axon |
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Pre-synaptic terminal area |
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transmitting element of neuron |
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Neurons form the basic signalling units of the NS, and are distinctly bound cells |
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Principle of Dynamic Polarization |
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Info within NS flows in a specific direction - always presynaptic to postsynaptic |
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Principle of connection specificity |
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a) No cytoplasmic continuity between cells b) Do NOT connect indiscriminately c) Rather, each neuron cell makes specific connection with some targets, and not others |
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one single neurite coming off the cell body. Typically only found in invertebrates. |
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2 neurites coming off cell body. Tend to be SENSORY information (project back towards CNS) |
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more than 2 neurites coming off cell body - example: spinal motor neuron |
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3 major classifications for neurons based on functionality |
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1) Afferent - sensory, project towards CNS
2) Efferent - motor, move out from CNS
3) Interneurons - project between afferent and efferent neurons, largest number of functional neurons within system |
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functions of Glial cells (list 7) |
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Definition
1) support - provide firmness and structure
2) form Myelin (Oligodendrocyte and Schwann cell)
3) scavengers - remove debris after injury/disease within CNS
4) buffers - maintain extracellular environment (Na&K) during high neuronal activity
5) During development, guide migration of neurons
6) form Blood Brain Barrier
7) possible nutritive value |
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Act as immune system - normal phagocytes are too big mobilized after injury, infection, and some diseases |
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Oligodendrocytes, Schwann cells, and Astrocytes |
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Fast Anterograde Axonal transport (forward moving) |
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Most newly synthesized organelles (mostly synaptic vesicles) within axon and dendrites transported this way. Move from 400-1000 mm/day. Relies on protein Kinesin to transport organelles. |
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Slow Anterograde Axoplasmic Transport |
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Definition
Cytosol transported down axon by this form of transport. Moves at rate of 3 mm/day, carries proteins used to make up fibrillar elements of cytoskeleton. Doesn't require extra energy, since elements travel with current. |
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Fast Retrograde Transport |
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Returns materials from terminals to cell body for degradation or restoration and reuse. Travel at a rate of about 200-400 mm/day. Travel along microtubules, relying on action of protein Dynin. |
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