Term
the learning of a motor response in reaction to sensory input. |
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Definition
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Nonassociative learning (2) |
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Definition
habituation and sensitization |
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Term
over time a stimulus has less and less impact on behavior. |
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Definition
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a strong sensory stimulus leads to increased responsiveness to other sensory stimuli. |
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Definition
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Term
Association of a stimulus that evokes a response with another stimulus that does not evoke this response. |
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Definition
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Term
US and CS must be simultaneous, or CS may precede US by a short interval. If CS follows US !92 no conditioning. |
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Definition
timing requirement of classical conditioning |
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Term
Classical conditioning involves learning a |
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Definition
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Term
learning to associate a motor response with a meaningful stimulus (e.g. a reward). learning the association between particular behaviors and their outcomes and consequences. The behavior must occur slightly before the stimulus |
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Definition
instrumental conditioning |
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Term
The 1Cstar 1D of invertebrate learning models |
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Definition
Aplysia californica (slug like) |
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Term
The nervous system of Aplysia contains about how many neurons? |
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Definition
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Term
: The gill withdrawal reflex in Aplysia shows |
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Definition
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Term
Cell L7 in the abdominal ganglion receives sensory input and connects to muscles. |
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Definition
Habituation of the gill withdrawal reflex |
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Term
Human memory involves structures in the |
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Definition
hippocampus and in the temporal lobes of the brain |
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Term
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Definition
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Term
record from cell in hippocampus area CA1 (receives Schaffer collaterals from area CA3). In addition, stimulate two sets of input fibers |
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Definition
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Term
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Definition
input specific and long-lasting |
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Term
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Definition
synaptic stimulation coincides with postsynaptic depolarization |
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Term
synaptic stimulation coincides with postsynaptic depolarization is acheived by |
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Definition
cooperativity of many coactive synapses during tetanus |
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Term
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Definition
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Term
LTP has what kind of characteristics? |
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Definition
Hebbian ( 1Cwhat fires together wires together 1D, or, in this case, connects together more strongly) |
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Term
Hippocampal responses can be modified in the direction of |
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Definition
potentiation (LTP) and depression (LTD) |
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Term
Long-term depression (LTD) in the hippocampus, triggered by |
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Definition
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Term
Most of the mechanisms of LTP/LTD are shared between |
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Definition
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Term
LTP/LTD play a role in synaptic rearrangements during |
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Definition
development and also during memory formation in the adult brain. |
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Term
How can one 1Cprove 1D that LTP/LTD underlie memory? (2) |
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Definition
1. Probing and stimulating/blocking of the molecules involved in LTP, especially the NMDA receptor.
2. Observing the effects of these manipulations on learning and behavior |
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Term
standard test for spatial memory in rodents |
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Definition
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Term
Rats with __________cannot learn/remember the location of the hidden platform. |
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Definition
bilateral hippocampal damage |
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Term
Injection of ________ into the hippocampus also abolishes behavioral improvement and learning (Richard Morris) |
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Definition
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Term
genetic manipulation of genes that make molecules thought to be involved in learning and memory |
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Definition
Gene knockout can be restricted to specific regions of the brain |
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Term
Does boosting the number of NMDA receptors produce an increase in memory performance? |
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Definition
Overexpression of NMDA receptors in genetically altered mice can result in enhanced learning (Joe Tsien, 1999). |
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