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Neuroscience Exam 3 Terminology
Terms for Neuroscience Exam 3
103
Medical
Professional
05/01/2011

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Term
Rods
Definition
photoreceptors with achromatic vision sensitive to low light
Term
Cones
Definition
photoreceptors with chromatic vision and acuity sensitive to more light
Term
Muller's cells
Definition
glial supporting cells for retinal neurons
Term
bipolar cells
Definition
connect photoreceptor cells to ganglion cells
Term
Drusen
Definition
composed of lipids/complement factors/matrix proteins, no effect on vision, hard (yellow) and soft (larger indistinct)
Term
metamorphosia
Definition
objects appear deformed
Term
Ophthalmic a.
Definition
blood supply to optic n.
Term
Ant. Communicating a.
Definition
blood supply to optic chiasm
Term
Ant. choroidal a.
Definition
blood supply to optic tract
Term
Thalamogeniculate a.
Definition
blood supply to lateral geniculate
Term
Pos. cerebral a.
Definition
blood supply to optic radiations and visual cortex
Term
Blindness
Definition
loss of both visual fields in an eye
Term
Hemianopia
Definition
loss of a visual hemifield (N or T)
Term
Quadrantanopia
Definition
loss of a visual quadrant (S or I)
Term
homonymous
Definition
visual field loss on same side of both eyes (i.e. L-T and R-N)
Term
heteronymous
Definition
visual field loss on different fields of both eyes (i.e. L-T & R-T)
Term
Brachium of superior colliculus
Definition
pathway of retinal ganglion cells on the way to the pretectal area
Term
Posterior commissure
Definition
crossing place of neurons from pretectal area on their way to the Edinger-Westphal nuclei
Term
Lesion of afferent limb of pupillary light reflex (optic n, optic tract, brachium of superior colliculus)
Definition
ipsi- no direct or consensual response
contra- direct and consensual response
Term
Lesion of efferent limb of pupillary light reflex (E-W fibers, fibers to ciliary ganglia, fibers to constrictor pupillae)
Definition
ipsi- no direct, yes consensual
contra- yes direct, no consensual
Term
Convergence
Definition
medial rectus m. contraction allows image to hit fovea of both retinas
Term
Accomodation
Definition
ciliary m. contraction releases tension on lens (rounds up)
Term
Flexner-wintersteiner rosette
Definition
around lumen, better prognosis in RB
Term
Homer-wright rosette
Definition
no central lumen, poor prognosis in RB
Term
Horizontal cells
Definition
synapse onto rods and cones, mediate surrounding response by GABA inhibition
Term
Amacrine cells
Definition
synapse onto bipolar and ganglion cells, inhibit opposite nearby ganglion cells
Term
Characteristics of Rod cells
Definition
night vision, low temporal resolution, scattered light, low acuity, achromatic
Term
Characteristics of Cone cells
Definition
day vision, high temporal resolution, direct axial rays, high acuity, chromatic
Term
Rod cilium
Definition
connect inner segment (cell nucleus) to outer segment (free-floating photopigment discs)
Term
M (magnocellular) cells
Definition
large receptive fields, input mainly from rods, analysis of gross features of stimulus/movement
Term
P (parvocellular) cells
Definition
small receptive fields, wavelength (color) sensitive, analysis of fine detail of visual image
Term
W cells
Definition
mixed functions, pupillary light reflex
Term
Lateral geniculate processing
Definition
ipsi: layers 2,3,5
contra: layers 1,4,6
M-cells: 1,2
P-cells: 3,4,5,6
Term
Simple cells
Definition
overlapping and adjacent fields form "on-center" zone, perpendicular=no response, increasing response as stimulus lines up with field
Term
Complex cells
Definition
simple cells with an axis of orientation, particular edge must be illuminated, increasing response with more stimulus
Term
movement-sensitive complex cells
Definition
must have proper orientation and direction of movement across receptive field, movement against receptive field decreases stimulus response
Term
Orientation columns
Definition
groups respond to stimuli along specific axis of orientation, 5-10 degree shift at each column
Term
Occular dominance columns
Definition
represent input from one eye
Term
hypercolumns
Definition
a pair of L&R occular dominance columns, retinotopic orientation
Term
Blobs
Definition
no specific orientation, involved in color processing
Term
V1
Definition
primary, basic visual processing of edges and orientation
Term
V2/V3/VP
Definition
continued visual processing
Term
V3A/MT/V5
Definition
visual motion
Term
LO
Definition
visual recognition of objects
Term
V8
Definition
color vision
Term
V4v/V7
Definition
unknown visual processing function
Term
Axonal degeneration
Definition
general/focal injury to an axon causes demyelination
Term
Segmental demyelination
Definition
schwann cell dysfunction
Term
Wallerian degeneration
Definition
axon damage distal to focal site (transection), remyelination shortens internode distance
Term
"onion bulbs"
Definition
schwann cells collecting around damaged axons during remyelination
Term
Lisch iris nodules
Definition
melanocytic hamartomas, well-defined yellow and brown on iris surface
Term
Corpus callosum
Definition
connects homologous lobes
Term
anterior commissure
Definition
connects temporal lobes and olfactory bulbs
Term
arcuate fibers
Definition
interconnect adjacent gyri
Term
cingulum
Definition
connects parahippocompal and cingulate gyri
Term
Superior occipitofrontal fasciculus
Definition
connects dorsal portions of frontal/parietal/occipital lobes
Term
Inferior occipitofrontal fasciculus
Definition
connects occipital/temporal/parietal lobes
Term
superior longitudinal fasciculus
Definition
connects all lobes and broca's/wernicke's areas IPSILATERALLY
Term
Uncinate fasciculus
Definition
connects frontal and temporal lobes
Term
Frontal lobe motor area (precentral gyrus-4)
Definition
voluntary movement
Term
Frontal lobe premotor area (6)
Definition
planning and initiation of voluntary movements
Term
Broca's area (44&45 of dominant hemisphere)
Definition
controls motor programs for muscles of speech
Term
Prefrontal association areas
Definition
weighing consequences, planning, motivation, personality
Term
Parietal multimodal association area (39,40)
Definition
integrate somatosensory/visual/auditory info, defines intra and extrapersonal space
Term
Occipital visual association areas (18&19)
Definition
interpretation of visual info
Term
Temporal wernicke's area (caudal 22 in dominant hemisphere)
Definition
comprehension of written an spoken language
Term
Beta waves (>14Hz)
Definition
desyncrhonized EEG, wide awake with eyes open
Term
Alpha waves (8-13Hz)
Definition
rest with eyes closed not concentrating, blocked when eyes are open (B-waves)
Term
Theta waves (4-7Hz)
Definition
parietal and temporal regions of children even when awake, adults indicative of light sleep and certain types of emotional stress
Term
Delta waves (<4Hz)
Definition
deep sleep, infancy, coma
Term
Stage 1 sleep
Definition
very drowsy, O-waves start appearing, responde to conversation but do not remember it
Term
Stage 2 sleep
Definition
light sleep, O-waves with sleep spindles (a-wave complexes) and k-complexes (large biphasic waves)
Term
Stage 3 sleep
Definition
moderately deep sleep, 20-50% d-waves, remainder are O-waves
Term
Stage 4 sleep
Definition
deep sleep, at least 50% large-amplitude d-waves
Term
REM sleep
Definition
paradoxial, EEG is B-wave, reflects wakefulness
Term
Characteristics of Slow-wave sleep
Definition
low metabolism/HR/BP/RR, no dreams, yes nightmares, enuresis and somnambulism (stages 3&4)
Term
Characteristics of REM sleep
Definition
desynchronized B-waves, irregular/faster HR/RR/muscle movement, decreased muscle tone, dreaming
Term
Passive theory of sleep initiation
Definition
result of CNS fatigue (reticular activating system)
Term
Active theory of sleep initiation
Definition
increase in synchronizing inputs, stimulation of certain areas causes sleep
Term
Acronia
Definition
underdevelopment of squamous bones of the cranium
Term
Megalencephaly
Definition
hyperplasia of brain
Term
Megalocephaly
Definition
largeness of head
Term
Microencephaly
Definition
hypoplasia of brain
Term
Microcephaly
Definition
smallness of head
Term
lissencephaly
Definition
agyria, absence of fissures/convolutions
Term
Primary epilepsy
Definition
idopathic
Term
Secondary epilepsy
Definition
due to trauma/anoxia/tumors/encephalitis/toxicity/withdrawal
Term
focal epileptogenesis
Definition
abnormal voltage channels, decreased inhibition and increased excitation
Term
Synchronization
Definition
decreased inhibition and increased excitation, alterations in ionic environment
Term
Propagation
Definition
alterations in ionic environment, recruitment of normal circuits
Term
Paroxysmal depolarizing shift
Definition
key characteristic of neruons in epileptic cortical zones
Term
Intractable seizures
Definition
do not respond to therapy
Term
+Chronotropic effects (shorten R-R interval)
Definition
SA node is principle pacemaker with spontaneous APs (overdrive suppression of slower pacemakers), Phase 4 pacemaker has positive slope in SA, time to threshold affected by rate of phase 4/starting point/threshold potential, B1-agonists increase phase 4 slope (increased HR)
Term
+Dromotropic effects (shorten P-R interval)
Definition
AV node conducts APs to ventricles, slow impulses allow ventricles to fill from atria before contracting
Term
First-degree AV block
Definition
abnormally long P-R intervals
Term
Second-degree AV block
Definition
occassional QRS dropped (mobitz type I) or periodic QRS dropped (mobitz type II), expressed as #P waves:#QRS complexes
Term
Third-degree AV block
Definition
AV dissociation
Term
+Inotropic effect
Definition
Frank starling mechanism (stretch optimizes posotion of contractile proteins and increased contraction), stretch measured by EDV and EDP, contractile force measured by SV, B1-agonists increase myocardial contractility
Term
+Lusitropic effects
Definition
increased rate of relaxation accompanies increased contractility
Term
Paroxysmal Supraventricular Tachycardia
Definition
accessory conduction between atria and ventricles, SA node reactivates atrial muscle for another contraction, palpations and inefficient ventricular filling
Term
Cluster A personality disorders (odd/eccentric)
Definition
schizotypal, schizoid, paranoid
Term
Cluster B personality disorders (dramatic/emotional/erratic)
Definition
borderline, narcissistic, histrionic, antisocial
Term
Cluster C personality disorders (anxious/fearful)
Definition
dependent, avoidant, obsessive-compulsive
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