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Neuroscience 524
Principles of Sensory physiology (somatosensory)
41
Science
Undergraduate 3
02/20/2011

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Term
Transduction
Definition
stimulus energy converted or coded into neural signals by a receptor.
Term
receptive field
Definition
area of the sensory epithleium which when stimulated elicits a response
Term
Peripheral innervation density
Definition
density of receptors across the sensory epithelium is often not uniform and this non uniformity is often functionally important.
Term
Perception
Definition
senation of stimuli
Term
Intensity
Definition
coded by discharge rate usually
Term
dynamic range problem
Definition
range of intensities can be perceived often exceeds the range coded by discharge rate of individual receptors
Term
modality
Definition
stimuli quality (often achieved by different sublcasses of rececptors)
Term
Adapation
Definition
Slow (tonic) or rapid (phasic)
Term
Localization of function
Definition
maintained throughout the aschending pathways
Term
Labeled lines
Definition
Muller's law of specific nerve energies: perceived sensation depends upon the RECEPTOR not necessarily the stimulus.
Term
Lateral inhibitiion
Definition
. Neurons that are firing suppress the stimulation of neighbouring neurons. In the face of inhibition, only the neurons that are most stimulated and least inhibited will fire, so the firing pattern tends to concentrate at stimulus peaks
Term
Cutaneous
Definition
Light touch and pressure (RAI and SAI)
Term
Subcutaneous
Definition
vibration and stretch (RAII and SAII)
Term
Proprioceptors
Definition
muscles and joints. muscle spindles. golgi tendons, joint receptors.
Term
A delta fibers
Definition
first or pricking pain. cold. well localized tonic. high threshold and large rf.
Term
C fibers
Definition
unmyelinated. second or b urning pain, diffuse, warm. tonic high threshold and large rf.
Term
Dorsal root
Definition
afferent axons
Term
Ventral root
Definition
Efferent axons (ventral horn contains motorneurons that innervate skeletal muscle)
Term
Spinal reflexes
Definition
modulated by descending influence
Term
white matter
Definition
outershell fo spinal cord, ascending and descending pathways.
Term
Dorsal column medial lemniscus
Definition
two point discrimination, vibration and proprioception. 1. Cutaneous and subcutaneous mechanoreceptors. Joint receptors. and trigeminal comnent for the head.
Term
Anterolateral/ spinothalamic
Definition
Pain and temp, some crude touch. also a trigeminal component for the head.
Term
Brown- Sequard syndrome
Definition
hemisection of the cord and it's symptoms.
Term
Lesions of Dorsal Column
Definition
loss of fine touch discrimination. (not total loss) and deficitis in sterognosis. (ability to identify objects by active touching.
Term
Anterolateral
Definition
nociceptors activation. electrical stimulation of dorsal columns can alleviate pain sensation. WIDE DYNAMIC RANGE NEURONS. exception to law of specific nerve energies.
Term
Dorsal column lesions
Definition
mildly affects cutaneous sensation.
Term
Sensory components of thalamic relay to cortex
Definition
VPL (ventral posterolateral for body
VPM Ventral posteromedial for face
Term
Primary somatosensory cortex
Definition
Parietal, Brodmann's areas 3a, 3b, 1 and 2.
Each contains a seperate map of the body surface.
Term
3a.
Definition
deep proprioceptors and muscle afferents
Term
3b.
Definition
simple receptive fields
Term
1
Definition
complex receptive fields (directional sensitivity and multidigit)
Term
2.
Definition
more complex receptive field. ie/ shape
Term
Peripheral innervation density.
Definition
distorted representation in different species depdnding upon use of body part. mouth and fingers in primates.
Term
Plastiity of cortical representation.
Definition
SI represention of body parts depends upon USE. ie/ whiskers remved, barrels disappear.
Term
Pacinian corpuscle
Definition
is RAII. vibration.
Term
Merkel's Disks
Definition
SAI pressure.
Term
Meisner corpuscle
Definition
RAI. light tough.
Term
Ruffini's corpuscles.
Definition
SAII stretch.
Term
mechanosensory afferent fibers
Definition
synapse onto dorsal root ganglion cells in spinal cord.
Term
medial wall cortical representation
Definition
the leg.
Term
coronal/sagital section
Definition
coronal what i cut in lab.
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