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Neuropsychiatric Effects of Brain Lesions on Behavior
Table 4-2 in BRS Behavioral Science
17
Medical
Graduate
02/07/2010

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Term
Frontal Lobes(dominant vs non-dominant)
Definition
Frontal Lobe
Mood Changes(depression with dominant lesions, elevation with non-dominant lesions)
Term
Dorsolateral Convexity Lesion
Definition
Frontal Lobe
Difficulties with motivation, concentration, attention, orientation and problem solving.
Term
Orbitofrontal Cortex Lesions
Definition
Frontal Lobe
Difficulties with judgment, inhibitions, emotions, personality changes.
Term
Broca Aphasia(Dominant Lesion)
Definition
Frontal Lobe
Inability to speak fluently
Term
Temporal Lobes
Definition
Impaired memory, psychomotor seizures, changes in aggressive behavior.
Term
Wernicke Aphasia(Dominant Lesion)
Definition
Temporal Lobe
Inability to understand language,
Term
Limbic Lobes
Definition
Poor new learning
Term
Hippocampus
Definition
Implicated specifically in Alzheimer's Disease.
Term
Amygdala
Definition
Kluver-Bucy Syndrome(decreased aggression, increased sex drive, hyperorality). Decreased conditioned fear response. Problems recognizing facial and vocal emotions in others, specifically anger.
Term
Parietal Lobes(right sided lesions)
Definition
Impaired processing of visual-spatial information(e.g. cannot copy line drawing or clock face properly)
Term
Gerstmann Syndrome; Dominant Lesions on Parietal Lobe
Definition
Impaired processing of verbal information.(e.g. cannot tell left from right, do simple math, name fingers, or write, etc.)
Term
Occipital Lobes
Definition
Visual hallucinations and illusions, inability to identify camouflaged objects, blindness
Term
Ventromedial Nucleus Damage
Definition
Hypothalamus
Hunger leading to obesity
Term
Lateral Nucleus Damage
Definition
Hypothalamus
Loss of appetite leading to weight loss
Term
Reticular System
Definition
Changes in sleep-wake mechanisms(e.g. decreased R.E.M. sleep)
Loss of consciousness
Term
Substantia Nigra
Definition
Basal Ganglia
Disorders of movement(e.g. Parkinsons)
Term
Caudate and Putamen
Caudate
Definition
Basal Ganglia
Huntington's Disease
Tourette Syndrome
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