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neurophysiology-receptor fxn
with cell signaling mech
18
Medical
Professional
05/16/2008

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Cards

Term
alpha-1
Definition
Gq - smooth muscle contraction
Term
alpha-2
Definition
Gi - inhibits NT release
Term
beta-1
Definition
Gs - inc HR and contractility
Term
beta-2
Definition
Gs - smooth muscle relaxation
Term
M1
Definition
Gq - affects CNS, PNS, gastric parietal cells
Term
M2
Definition
Gi - dec heart rate and contractility
Term
M3
Definition
Gq - stimulates glandular secretions
Term
D1
Definition
Gs - smooth muscle relaxation; natriuresis; CNS effects
Term
D2
Definition
Gi - inhibits sympathetic transmitter release; CNS effects
Term
V1
Definition
Gq - smooth muscle contraction (via ADH)
Term
V2
Definition
Gs - inc water reabsorption in kidney (via ADH)
Term
insulin
Definition
tyrosine kinase - inc glycogen synthesis; dec glycogenolysis
Term
glucagon
Definition
Gs - inc glycogenolysis; dec glycogen synthesis
Term
IGF
Definition
insulin-like growth factor; via tyrosine kinase; inc proliferation of various cell types
Term
PDGF
Definition
platelet-derived growth factor; via tyrosine kinase; inc proliferation of CT, glial and SM cells
Term
EGF
Definition
epithelial growth factor; via tyrosine kinase; inc proliferation of mesenchymal, glial, and epithelial cells
Term
ANF
Definition
atrial natriuretic factor; via guanyl cyclase; smooth muscle relaxation; inc Na+ and H2O excretion in kidney
Term
NO
Definition
via guanyl cyclase; smooth muscle relaxation
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