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NeuroPhysiology Exam II Material
Exam II Material
99
Science
Undergraduate 4
11/03/2010

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Term
yawning
Definition
This is the fixed action pattern that humans share with other animals
Term
Cardiac-somatic concept
Definition
This is the concept that the cardiac response is seen as facilitating the preparation for, and performance of a behavioral response.
Term
Habituation/extinction
Definition
This principle predicts a cessation of physiological response under prolonged stimulation.
Term
Stereotopy
Definition
This law predicts behavior that is species-specific and invariant.
Term
6 characteristics of stereotopy
Definition
Behavior always takes the same form. Universality – found throughout the species. Independent of experience (no learning necessary). Ballistic – once initiated must proceed to end. Singleness of purpose – used in only one context. Has a triggering stimulus.
Term
Law of Initial Values
Definition
This law states that a particular physiological response to a given stimulus depends on the pre-stimulus level.
Term
Autonomic Balance
Definition
This theory is based on the relative dominances of the SNS and PNS.
Term
Yerkes-Dodson Law
Definition
This law postulates an optimal level of arousal for any task given its complexity
Term
electromyography
Definition
method evaluates the electrical activity produced by muscles.
Term
Blood pressure
Definition
This method looks at the pressure exerted by circulating blood. Based on highest (systolic, when the ventricles are empty) and lowest (diastolic, when the ventricles are full) pressure.
Term
Galvanic skin response
Definition
This method was used to detect lies.
Term
electrogastroenterography
Definition
This method reflects the contraction of smooth muscle and measures waves of activity that vary according to which of 5 structures you are measuring
Term
Sham
Definition
This is the name of the lesions used to control for actual experimental lesions
Term
Wada technique
Definition
This chemical technique uses carotid injections to for a reversible lesion.
Term
Hemodynamic response related to neural activity
Definition
response measured by fMRI
Term
Formalin injection
Definition
used to harden tissue for desiccation
Term
Paraffin bath
Definition
use alcohol to remove water from tissue
Term
Freeze Harden
Definition
cryo preservation of tissue
Term
Eosin
Definition
used to dye cytoplasm
Term
Luxol-fast blue
Definition
axons (used to test for multiple sclerosis in tissue samples).
Term
Cresyl violet
Definition
dendrites and nissl bodies (used in Alzheimer's research and locating stem cells).
Term
Intravenous
Definition
This is the fastest but most dangerous form of drug administration
Term
Haptic senses
Definition
is the term used to refer to the sensations of pressure, pain, temperature, and proprioception. Are necessary for normal growth in newborns
Term
Glabrous (non-hairy) and nonglabrous (hairy)
Definition
These are the two types of skin
Term
Adaptation and receptive field size
Definition
These are the two dimensions in which the four mechanoreceptors differ.
Term
Ruffini’s ending and Pacinian corpuscle
Definition
These are the two mechanoreceptors that have large receptive fields.
Term
A-delta and C fibers: A-dellta fibers account for the sharp, first pain, while C fibers account for the duller second pain
Definition
Information about pain and temperature are transmitted by these axons.
Term
A-beta
Definition
This is the largest and fastest axon of the primary afferent axons.
Term
Ipsilateral dorsal horn of spinal column
Definition
side of the spine where touch and proprioception ascend.
Term
Touch and Pain pathways are segregated
Definition
Pain decussates immediately and touch decussates at the hindbrain (medulla).
Term
3
Definition
roots of the spine have to be cut to lose all sensation from an area of the dermatome
Term
Pacinian corpuscle
Definition
mechanoreceptor is sensitive to ground vibration
Term
Cauda equina
Definition
area of the spine is where lumbar punctures are performed.
Term
TRPV1
Definition
temperature receptor responds only to hot stimuli, e.g., capsaisin
Term
TRPM8
Definition
This temperature receptor responds only to cold stimuli, e.g., menthol
Term
Substance P
Definition
This peptide is synthesized by the nociceptors themselves and is necessary for moderate or intense pain.
Term
Bell’s palsy
Definition
Disease resulting from dorsal root ganglia becoming infected with Herpes zoster.
Term
(A)stereoagnosia
Definition
disorder that causes an inability to recognize common objects by feeling them even though they can be recognized by sight or sound
Term
prosopagnosia
Definition
is the disorder in which you are unable to recognize familiar faces
Term
anosagnosia
Definition
Inability to recognize that one has a problem (unawareness of disorder).
Term
anosodiasphoria
Definition
Failure to believe that you have a problem (indifference to disorder).
Term
autopagnosia
Definition
inability to localize and name a person's own body parts
Term
Optic Ataxia
Definition
Deficit in visually guiding hand movements
Term
Ataxia
Definition
dysregulation of movement and coordination
Term
Asymbolia for pain
Definition
Absence of the normal ability to acknowledge pain
Term
Prosopagnosia
Definition
deficit in recognizing familiar faces
Term
Agnosia
Definition
— a loss of ability to recognize objects, persons, sounds, shapes, or smells while the specific sense is not defective nor is there any significant memory loss
Term
Neglect Syndrome
Definition
a person can only acknowledge one object when two are presented
Term
Smooth Muscle
Definition
located within walls of hallow organs, that regulates substance travel.
Term
Cardiac Muscle
Definition
forms middle layer of the heart (myocardium) with cells connected by gap junctions, causing uniform contraction
Term
Skeletal Muscle
Definition
muscle attached to the skeletal structure that is subject to voluntary movement.
Term
Alpha motor neurons
Definition
These motor neurons innervate extrafusal muscle fibers, and directly trigger the generation of force by muscle
Term
The stretch reflex
Definition
When a muscle is stretched, sensory neurons within the muscle spindle detect the degree of stretch and signal the CNS, which activates alpha motor neurons to cause extrafusal muscle fibers to contract.
Term
Myotactic reflex
Definition
This reflex explains why stretched muscles tend to “unstretch” or pull back.
Term
Dorsal root ganglion cells, upper motor neurons, interneurons in spine
Definition
These are the 3 major sources of input to an alpha motor neuron.
Term
Eccles
Definition
found that phenotype of fast muscle changed to phenotype of slow muscle when he replaced the innervations of a fast muscle with a nerve that normally innervated slow muscle.
Term
Excitation-contraction coupling
Definition
This is what happens at the nicotinic receptors to produce a muscle contraction.
Term
Rigor mortis
Definition
This is the condition produced by starving muscle cells of ATP, leaving myosin attached on actin filaments
Term
Corticospinal tract
Definition
This is the most important descending tract.
90% of fibers decussate at the medulla
Term
Rubrospinal tract
Definition
is thought to be the “back-up system” for the corticospinal tract
Term
Most distal phalanges
Definition
movements that are never recovered after lesions of the corticospinal tract.
Term
Vestibulospinal and tectospinal tracts
Definition
These two tracts keep your head balanced on your shoulders and orient your head to new stimuli.
Term
cerebellum
Definition
responsible for guiding target-oriented movements (smaller in children with ADHD).
Term
tectospinal tract
Definition
responsible for “blindsight.”
Term
major difference between Area 4 and Area 6 motor cortex
Definition
Similar functions but on different motor groups, SMA sends axons directly to distal motor units, PMA connects primarily with reticulospina neurons that innervate proximal motor units.
Term
Premotor cortex
Definition
This motor area is involved in learning and executing complex movements guided by sensory information.
Term
Prefrontal and posterior parietal cortex
Definition
represent the HIGHEST levels of the motor control hierarchy where decisions are made about what actions to take and their likely outcomes
Term
ataxia
Definition
Uncoordinated and inaccurate movements.
Term
***dysynergia
Definition
Decomposition of synergistic multijoint movements.
Term
dysmetria
Definition
Overshoot or undershoot in targeted reaching
Term
Huntington’s disease
Definition
Inherited disease that targets the area of the basal ganglia known as the neostriatum.
Term
Egas Moniz
Definition
won the Nobel Prize for developing a form of brain surgery known as frontal lobotomy
Term
Walter Freeman
Definition
used ice picks to perform drive-through lobotomies
Term
Jose Delgado
Definition
manufactured and programmed the first brain computer chip
Term
Warren Penfield
Definition
mapped the somatosensory and motor strips for the first time
Term
Jim Olds
Definition
discovered the brain’s pleasure center (medial forebrain bundle).
Term
Roger Sperry
Definition
won the Nobel prize in Medicine for his split-brain research
Term
Karl Lashley
Definition
spent his life trying to localize memory
Term
Brenda Milner
Definition
with the famous memory patient HM and showed that medial temporal lobe amnestic syndrome is characterized by the inability to acquire new information
Term
William James
Definition
tested cerebral blood flow on a tilt table
Term
George Stratton
Definition
turned the world upside-down and backwards with goggles and proprioception
Term
Vasopressin
Definition
Neurohormone that regulates blood volume and salt concentration
Term
cortisol
Definition
This neurohormone suppresses your immune system
Term
***norepinephrine
Definition
The major post-ganglionic neurotransmitter of the sympathetic nervous system
This neurotransmitter is associated with Huntington’s disease
Term
acetylcholine
Definition
This neurotransmitter is linked to Alzheimer’s disease
Term
homeostasis
Definition
The process that regulates body temperature and blood composition despite changing inputs.
Term
Solitary tract and nucleus
Definition
This tract conveys taste information and is located along the length of the medulla.
Term
Raphe nuclei
Definition
This structure provides feedback to the suprachiasmic nuclei thus contributing to circadian rhythms
Term
Nucleus accumbens
Definition
This structure is maximally involved in motivation
Term
accumbens, ventral tegmental area
Definition
The brain area is involved in addiction
Term
Nigro-striatal pathway
Definition
This pathway uses primarily dopamine
Term
nMRI
Definition
uses iron present in hemoglobin to map brain function
Term
fMRI
Definition
Uses iron present in hemoglobin to map the brain anatomy
Term
Muscle spindle
Definition
This structure is responsible for stretch reception and the sensory component of the tendon reflex.
Term
major difference between CT and MRI
Definition
CT uses a LOT of ionizing radiation
Term
Activation
Definition
This is thought to reflect arousal
Term
Enter at dorsal horn and then branch
Definition
This is the point at which touch an proprioception decussate on their way to the brain.
Term
Stimulus-response specificity
Definition
This is the concept that states that an individual’s response will be similar in a given situation and will change when the environment changes
Term
Lower motor neurons
Definition
Sherrington called these the “final motor pathway.”
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