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the study of the actions of drugs and their effects on
living organisms
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study of the effects of drugs on the nervous system
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Describes the effects of drugs on psychologic parameters such as moods and cognition
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All-encompassing term applied to all types of drug effects that influence nervous system function
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How the body moves drugs throughout it’s systems (i.e. What the
body does to the drug)
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How the drug powers the body and it’s systems (i.e. What the drug does to the body)
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The influence of an individual’s genes in determining the response to a particular drug
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refers to specific molecular changes that occur when a drug binds to a particular target site or receptor |
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are the resulting widespread alterations in function |
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intended effect on the body |
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any effect on the body that is not the therapeutic effect |
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specific drug effect vs. non-specific drug effect |
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Definition
specific drug effect occurs at the site of binding, while the non-specific effect is the resulting effects |
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the amount of drug in the blood that is free to bind at specific target sites |
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how is bioavailability determined?
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Definition
1. Administration
2. Absorption and distribution
3. Binding
4. Inactivation
5. Excretion
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