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Neurology basics
n/a
18
Biology
Graduate
02/04/2013

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Term
What are three types of diffuse neuron/neuron communication?
Definition
1) divergence: 1 neuron synpases w/ many other neurons
2) volume: 1 neuron has no special connections with any neuron, but just approximates quite a few neurons
3) neuroendicrine
Term
What are the basal ganglia?
Definition
caudate nucleus, pudamen, globus pallidus
Term
what is the striatum?
Definition
caudate nucleus + putamen
Term
what is the lenticular nucleus?
Definition
putamen + globus pallidus
Term
what is the main function of the basal ganglia? Secondary?
Definition
Main - regulating movement
secondary - cognition
Term
what are the main components of the limbic system?
Definition
amygdala, hippocampus, hypothalamus, cingulate gryus (collection of gray matter loci above corpus callosum)
Term
where do axons in the corticospinal pathway cross the midsagittal plane?
Definition
at the lowest parts of the medulla
Term
What function is associated with "ventral?" With "dorsal?"
To which structures can this relation be applied
Definition
ventral -> motor, dorsal -> sensory. Apply relationship to brain, thalamus, spinal chord
Term
If the right leg loses ability to sense vibration at 128 Hz and the left leg loses ability to feel cold, where is the lesion? Which leg may have loss of motor?
Definition
On the right side, involving the entire half of the spinal chord near the level of the DRGs for the two appendages. The right leg will also have loss of some motor.
Term
What are the 2 subdivisions of the cerebrum?
Definition
Diencephalon, hemispheres
Term
What type of cell lines ventricles?
Definition
Ependymal cells
Term
What are the paracrines that cause neuron survival/growth?
Definition
neurotrophins
Term
what is the first embryological step of early brain development?
Definition
formation of three primary vesicles (pros/mes/rhombencephalon)
Term
what are the names for the primordial divisions between affarent and efferent neurons in the brainstem/spinal chord? What separates them?
Definition
The sulcus limitans separates the alar plate (afferent) from the basal plate (efferent). N.B. - in the brainstem, alar plates moves lateral to basal plate, but remains dorsal in the spinal chord.
Term
What is the mechanism of developing neuron growth?
Definition
A growth cone sends out multiple projections to see which way is farther from chemorepulsion/contact inhibitors and which is closer to chemoattractants.
Term
What are three mechanisms of diffuse non-synaptic modulation of neurons?
Definition
volume, endocrine, divergence
Term
What are effects of cocaine on brain epinephrine, norepinephrine, serotonin, and dopamine?
Definition
Cocaine blocks NE and dopamine reuptake
Term
what is the order of catecholamine synthesis?
Definition
tyrosine-> dopa -> dopamine -> NE -> Epinephrine
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