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Definition
| CAUSED BY degeneration of DOPAMINE producing neurons in the substantia nigra of the mid brain. Characterized by slowness in initiation and execution of movement (bradykinesia), increased muscle tone (rigidity), tremor at REST and gait disturbance. Can start on one side. |
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| Disease is caused by chronic autoimmune degeneration of MYELIN SHEATH in CNS and subsequent plaque formation. Characterized by weakness/paralysis of limbs/trunk/head, diplopia, scanning speech, spastic muscles, numbness/tingling, blurred vision, vertigo, tinnitus, decreased hearing and chronic neuropathic pain, nystagmus, ataxia, dysarthria, dysphagia. Sclerotic plaques detected by MRI. |
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| Autoimmune condition where antibodies attack ACh receptors at neuromuscular junctions preventing ACh from stimulation muscular contractions |
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| deficiency of neurotransmitters ACh and Gamma-aminobutyric acid (GABA). , Genetic Autosomal dominant disorder, OPPOSITE of PD, this disease involves Abnormal excessive invol. movements (chorea) like twisting and writhing of face, limbs and body w/ COG def. in perception, memory, attention and learning. |
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| MOST serious type of food poisoning (12-36hr onset), disrupted ACh neurotransmission at neuromuscular junctions, INTACT MENTAL ALERTNESS with descending paralysis with cranial nerve deficiets (also accompanied by nausea, vomiting, diarrhea, abdominal cramping) |
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| Neural tube defect (doesn't close all the way); unfused portion of spinal column allows the nervous tissue to protrude which is damaged or not properly developed. |
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| Tumors develop on the supporting nerve cells like the myelin sheath causing changes in skin coloration (cafe au lait spots), tumor on optic nerve, growths on the iris and manifests by age 10. |
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| Bleed into space btw dura and arachnoid layers usu from VEINS, arterial hemmorhage less common and develop rapidly, three types SUBDURAL hematome (acute, subacute and chronic), chronic subdural can dev over weeks or months post head injury usu in older adults and is frequently misdx as dementia (caused by atrophy of brain which leads readily to tearing of brain tissue) |
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Definition
| Bleed btw dura and inner surface of skull is a NEUROLOGIC EMERGENCY venous/arterial, from a linear skull fx crossing major artery; classic signs include unconciousness at the scene, brief lucid interval followed by decreased LOC, w/ HN&V |
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Definition
| weakness and ballooning of cerebral blood vessels (acquired or congenital) that can burst and lead to subarachnoid hemorrhage or hemorrhagic stroke |
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| Pus in brain tissue that can result FROM local or system infections. |
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| Cranial Nerve 5: sudden, unilateral stabbing burning pain along nerve pathways in face/U/L gums, cheek, forehead but esp the maxillary and mandibular branches.S |
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| Blockage of flow of CSF, symptoms include dementia urinary incont., difficulty walking, can be caused by spinal mg, encephalitis or head injury |
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Definition
| Autoregulation is often lost during the first few hours of TBI; can lead to anterior pituitary dysfunction ESP r/t ADH release/not enough |
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Term
| What is the effect of hypoxemia on CBF? |
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Definition
| Low blood oxygen increases CBF, esp PaO2 below 50 torr |
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