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neurobiology intro
neurobiology intro
112
Biology
Undergraduate 4
02/10/2008

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Term
cephalic flexure
Definition
the bend that the brain takes in the occipital lobe
Term
decussate
Definition
In the brain, where nerve fibers cross from one lateral part to the other
Term
ANS
Definition
The autonomic nervous system (ANS) (or visceral nervous system) is the part of the peripheral nervous system that acts as a control system, maintaining homeostasis in the body.
Term
somatic nervous system
Definition
The somatic nervous system is the part of the peripheral nervous system associated with the voluntary control of body movements through the action of skeletal muscles, and with reception of external stimuli, which helps keep the body in touch with its surroundings (e.g., touch, hearing, and sight).
Term
efferent
Definition
In the nervous system, efferent nerves – otherwise known as motor or effector neurons – carry nerve impulses away from the central nervous system to effectors such as muscles or glands (and also the ciliated cells of the inner ear).
Term
afferent
Definition
In the nervous system, afferent neurons--otherwise known as sensory or receptor neurons--carry nerve impulses from receptors or sense organs toward the central nervous system.
Term
superior temporal sulcus
Definition
sulcus right below the sylvian fissure
Term
pre-occipital notch
Definition
notch in theback of the occipital lobe
Term
median longitudinal fissure
Definition
you know where (middle of brain)
Term
parieto-occipital fissure
Definition
the fissure on the midsagittal cortex towards the occipital lobe
Term
calcarine sulcus
Definition
the sulcus that splits the occipital fissure in half
Term
frontal eye field
Definition
BA 8
Term
prefrontal cortex
Definition

BA 9, 10, 11, 12 and 46

 

aka the frontal association areas 

Term
Broca's area (dominant side)
Definition
BA 44, 45
Term
premotor/supplementary motor cortex
Definition
BA 6
Term
Primary motor cortex
Definition
BA4
Term
homunculus
Definition
The homunculus is also commonly used to describe the distorted human figure drawn to reflect the relative space our body parts occupy on the somatosensory cortex (sensory homunculus) and the motor cortex (motor homunculus). The lips, hands, feet and sex organs have more sensory neurons than other parts of the body, so the homunculus has correspondingly distortedly large lips, hands, feet, and genitals. Well known in the field of neurology, this is also commonly called 'the little man inside the brain.'
Term
orbitofrontal cortex
Definition

The orbitofrontal cortex (OFC) is a region of association cortex of the human brain involved in cognitive processes such as decision-making. The name of this region is based upon the region's location within the frontal lobes, resting above the orbits of the eyes. part of the limbic system

 

[image]

Term
precentral sulcus
Definition
The precentral sulcus lies parallel to, and in front of, the central sulcus.
Term
primary somatosensory cortex
Definition
BA 3,2,1
Term
somatosensory association areas
Definition
BA 5,7
Term
supremarginal gyrus
Definition
BA 40
Term
Angular gyrus
Definition
BA 39
Term
Sir Henry Head
Definition
helped map origins of the somatosensory pathways by probing open head wounds and section his own nerves
Term
higher level visual cortex
Definition
BA 18, 19
Term
Primary visual cortex
Definition
BA 17
Term
Primary visual cortex
Definition
BA 17
Term
visual association cortex
Definition
BA 18, 19
Term
the insula
Definition
inside behind heschl's gyrus
Term
Heschl's gyrus
Definition

BA 41, 42

 

Primary auditory cortex 

Term
Wernicke's Area
Definition
BA 22 in the DOMINANT HEMISPHERE
Term
Primary vestibular cortex
Definition
BA 22
Term
Temporal visual association area
Definition
BA 20, 22, and 37
Term
fusiform cortex
Definition
BA 37
Term
neurobiology
Definition
the study of neural tissue
Term
parahippocampal gyrus
Definition
the gyrus that has the hippocampus
Term
amygdala
Definition
right next to the hippocampus
Term
internal capsule
Definition
The internal capsule is an area of white matter in the brain that separates the caudate nucleus and the thalamus from the lenticular nucleus.
Term
internal capsule
Definition
contains both corticospinal and coticofugal fibers
Term
anterior commisure
Definition
commisural fibers
Term
association fibers
Definition
Any of the nerve fibers connecting individual subdivisions of a brain structure or different segments of the spinal cord.
Term
Basal Ganglia
Definition

aka Basal Nuclei

 it is grey matter

 

Three main nuclei:  

caudate nucleus, putamen and globus pallidus 

Term
striatum
Definition
the caudate nucleus and the putamen
Term
lenticular lens
Definition
the putamen and the globus pallidus
Term
corpus striatum
Definition
the caudate nucleus, putamen and the globus pallidus
Term
projection fibers
Definition
anterior limb, genu and the posterior limb (of the internal capsule)
Term
Fornix
Definition
the fornix has the body and the columns
Term
the diencephalon
Definition
gives rise to the thalamus and the hypothalamus as well as the epithalamus and the subthalamus
Term
Autonomic nervous system
Definition
neuronal and hormonal control of homeostasis
Term
The thalamus
Definition

GATEWAY TO THE CORTEX

 

relay station for ASCENDING info

 

integrates info too 

Term
the thalamus
Definition
contains the pulvinar, the lateral geniculate, the medial geniculate
Term
the epithalamus
Definition
has the pineal gland
Term
cerebellum
Definition
don't forget that it has hte vermis and the cerebellar hemispheres
Term
Arbor vitae
Definition
the white matter in the cerebellum
Term
The brainstem
Definition
has a dorsal and ventral side to it
Term
dorsal brainstem
Definition
the superior colliculis, the inferior colliculus, the suerpior cerebellar peduncle and the middle cerebellar peduncle
Term
ventral brainstem
Definition
has the pons, pyramid, olive and medulla
Term
spinal cord - dorsal side
Definition
has the dorsal roots, denticulate ligaments, and dorsal columns
Term
the spinal cord
Definition

the white matter increases from caudal to rostral

 

the shape changes from round to oval

 

the enlargements in the ventral horns serve the extremeties 

Term
spinal cord
Definition

the posterior median sulcus separates the top dorsal column into left and right halves

 

the anterior median FISSURE separates the botton ventral column into left and right halves 

Term
spinal nerve
Definition
where the dorsal ganglion (dorsal root) and the ventral roots come together
Term
dermatome
Definition
Dermatomic area (also known as a dermatome) is an area of skin that is supplied by a single pair of dorsal roots.
Term
cranial vasculature - arteries
Definition

two pair of major arteries supply the brain:

 

the internal carotids 

 

the vertebral arteries

 

they both stem off of the aorta 

Term
circle of willis
Definition
the circle vasculature structure
Term
internal carotids
Definition
distribute blood to the brain through the anterior, middle and posterior cerebral arteries
Term
cranial meninges
Definition
know the different layers protecting the brain
Term
the ectoderm makes neural crest cells which...
Definition
make the schwann cells, neuroglial cells and the para/sympathetic nervous system
Term
the ectoderm makes the neural tube which makes...
Definition
the spinal cord, brain and retina
Term
neural plate
Definition
the tall cells in which the notocord and the neural tube form. they converge and make neural crest cells too.
Term
spinal cord
Definition
needs folate to close
Term
Dysraphic Defects
Definition

where the neural tube does not zip up completely.

 

spina bifida and anencephaly 

Term
the cephalic end of the neural tube
Definition
deveops into the brain
Term
forebrain or the prosencephalon
Definition
develops into the telenceplalon and the diencephalon
Term
rhonbemcephalon
Definition
develops into the pons and the medulla
Term
epithalamus
Definition
contains the pineal body
Term
chiari malformation
Definition

The cerebellar tonsils are elongated and pushed down through the opening of the base of the skull (see foramen magnum), blocking the flow of cerebrospinal fluid (CSF).

The brainstem, cranial nerves, and the lower portion of the cerebellum may be stretched or compressed.

Term
the rhombencephalon
Definition

later differentiates into the metencephalon that becomes the pons and cerebellum and then the

 

mylencephalon: the medulla 

Term
the neural tube contains
Definition

ectodermal precursers are located here and signalling proteins determine the plarity, connections and function of the precursor cells

 

Term
basic events of neurognesis
Definition

neurogenesis

migration

connection

cell pruning 

Term

neural tube

germinal layer 

Definition
corms neuroblasts and spongioblasts
Term
the mantle layer of the neural tube
Definition
consists of cells derived from the germinal layer
Term
marginal layer of the neural tube
Definition
contains cellular extensions
Term
radial glial cell
Definition
a long cell that is a scaffold for a migrating neuron in the neural tube
Term
the neural tube
Definition
has a ventricular zone, an intermediate zone and a marginal zone
Term
sensory growth cones and the spinal cord
Definition
they enter the spinal cord
Term
nerves entering the dorsal portion of the spinal cord
Definition
sensory
Term
nerves exiting the ventral portion of the spinal cord
Definition
motor
Term
the floor and roof plates of the spinal cord
Definition
they contain NEUROGLIA
Term
undifferentiated cells surrounding the neurocoel become..
Definition
ependymal cells
Term
migration of the neuroblasts along radial glia from the mantle zone to the marginal zone results in the formation of...
Definition

the NEOCORTEX

 

it is an inside-out formation 

Term
the neocortex
Definition
the grey matter in the cerebrum
Term
lissencephaly
Definition
where the neurons do not make it to the marginal layer and therefore have "smooth" gyri or the lack of.
Term
dendritic spine
Definition
the membranous protrusion from the dendrite that receives information from axons - increases surface area
Term
purkinje cell
Definition
a golgi type I cell that has long axons and always is found in the cerebellum. also has lots of dendritic spines
Term
telodendria
Definition
The terminal branchings of the dendrites. They have enlarged ends called presynaptic terminals with vesicles containing neurotransmitters.
[image]
Term
orthograde transport
Definition
fast axoplasmic flow that is bidirectional
Term
golgi type I neurons
Definition
have long axons
Term
golgi type II neurons
Definition
have short axons
Term
there are three types of neurons
Definition
afferent (sensory), efferent (motor) and association which is communication between the two
Term
astrocytes are receptors for...
Definition
NE, substance P, GABA, glutamate
Term
astrocytes secrete...
Definition
cytokines, growth factors and IMMUNE mediations
Term
astrocytes help with the...
Definition
BBB
Term
three major types of astrocytes (macroglia) are...
Definition
radial glia, protoplasmic glia, and fibrous glia
Term
the BBB
Definition

capillaries in the brain do not have pores between adjacent endothelial cells

molecules within the brain capillaries moved selectively through endothelia cells by diffuson, active transport, endocytosis or exocytosis

 

basically, the glial cells form a tight junction around the capillaries and then control what goes in and what goes out 

Term
astrocytes...
Definition
also repair damaged tissue
Term
oligodendrocytes are
Definition

ectodermal

 

satellite,

 

interfasicular oligodendrocytes are for myelin 

 

vascular oligodendrocytes have perivascular attachments 

Term
microglia
Definition

MESODERMAL

 

gitter cells: rod-like structures that are a source of secondary damage after a stroke - can inflame by their secretions 

Term
ependymal cells
Definition

they are coliated and microviliated

 

there are tanycytes and choroidal epithelial cells 

Term
Neuroglia in the PNS
Definition

satellite cells: for the dorsal root ganglia and

 

schwann cells for myelin and regeneration 

Term
tumors
Definition
ONLY CAUSED BY GLIA
Term
Tumors part II
Definition

astrocytomas are the most common

 

oligodendrocytomas are in the cortical lobes

 

ependymomas are in children and adults

 

meningiomas are benign

 

metastasis 

Term
Tumors in Kids
Definition

neuroblasts don't know when to stop growing

 

unrestricted growth

 

agressive and are called medulloblastomas 

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