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Neurobiology Ch 8
Synaptic Plasticity
5
Biology
Undergraduate 4
03/19/2014

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Term
What is plasticity?
Definition
Term that refers to structural or functional changes in the nervous system, or the ability to make such changes
Term
Associativity


Augmentation


Coincidence detector
Definition
In the hippocampus, the enhancement of a weakly activated group of synapses when a nearby group is strongly activated.


Repeated synaptic activity, increase in neurotransmitter release from presynaptic terminals (rise and fall within a few seconds)


process by which a neuron or a neural circuit can encode information by detecting the occurrence of temporally close but spatially distributed input signals (pg 171)
Term
Habituation


Long-term depression (LTD)


Long-term potentiation (LTP)
Definition
Less responsive to a repeated occurrence of stimulation


A persistent weakening of synapses based on recent pattern activity


A persistent strengthening of synapses based on recent pattern activity
Term
Post-tetanic potentiation (PTP)


Potentiation


Sensitization
Definition
An enhancement of synaptic transmission resulting from high-frequency trains of action potentials


Repeated synaptic activity to increase neurotransmitter release (rise and fall lasting from ten of seconds to minutes.)


Increased sensitivity to a stimuli in the area of injury. Also, a generalized aversive response to an otherwise benign stimulus when it is paired with a noxious stimulus
Term
Spike timing-dependent plasticity (STDP)


Synaptic depression


Synaptic facilitation
Definition
Timing-dependent activity, probably the result of Ca2+ signaling in the postsynaptic cell, that is required for the establishment of some forms of synaptic plasticity


A short-term decrease in synaptic strength resulting from depletion of synaptic vesicles at active synapses.


A rapid increase in synaptic strength that occurs when two or more action potentials invade the presynaptic terminal within a few milliseconds of each other.
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