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Neuroanatomy
neuropathies
42
Anatomy
Graduate
12/07/2009

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Term
Peripheral Nerve Damage
Definition
Associated with sensory disturbances & autonomic in addition to weakness
Term
Radiculopathy
Definition
Damage to the nerve as roots merge (Localized) could be:IV disc herniation, cervical spondylosis, osteophyte
Causes sensory loss, pain,myotomal & reflex loss
Term
Dermatome
Definition
Sensory neurons w/in a single spinal nerve innervate specific areas of skin
Term
Plexopathy
Definition
Damage to brachial/lumbar plexuses, Unilateral motor limb involvement affecting limb. Loss of reflexes or sweating
Term
Peripheral Neuropathy
Definition
Assoc. w/ specific nerve. Damage to myelin sheath leads to damage to axon, decreased nerve conduction. can cause degeneration of nerve distal to leison
Term
Erb Duchene's Palsy
Definition
Damage to ventral rami of C5, C6. "Waiter's Tip" (Upper trunk injury)Happens in motorcycle or babies being born--neck area
Term
Klumpke Palsy
Definition
(lower trunk injury)Damage to ventral rami C8, T1. Happens when you catch yourself from a fall, Thoracic Outlet/pancoast tumor. Sensory loss from C8 & T1 derms.
Term
Wallerian Degeneration
Definition
Axonal damage that results in degeneration of the portion of the neuron that is distal to the leison
Term
Localized Mononeuropathies
Definition
Damage ot a single peripheral nerve due to trauma or compression. (carpal tunnel syndrome)
Term
Symmetrical Polyneuropathies
Definition
Involve multiple nerves affecting distal extremeties (ex. diabetic neuropathy)
Term
Neuromuscular Junction disorder
Definition
Fluctuating weakness(fatigue) w/o sensory loss
Term
Myasthenia gravis
Definition
a Neuromuscular Junction disorder. Where nicotinic ACTYL receptors of the NMJ are targeted by antibodies
Weakness affects proximal & facial muscles and you do hae reflexes and cholinergic autonomic functions
Term
Polymyositis
Definition
Autoimmune Muscle disease w/ or w/o atrophy, normal sensation & intact reflexes. Controlled w/ corticosteroids
Serum creatin phosphokinase is elevated due to muscle damage.
Term
Duchenne Muscular Dystrophy
Definition
A muscle disease caused by genes only males. Dystrophen gene that is a protein important for structural integrity of muscle. Chronic/progressive, decreased reflexes,death young.
Term
Meningeal Headaches
Definition
Irritation of meninges due to infection. Above Tent-face affected Below Tent-back of head & neck affected.
Term
Epidural(Extra) Hematoma
Definition
(pterion) Middle meningeal artery is damaged from a blow to the head. Dura is stripped away from the inner part of skull and the blood collects.can be fatal
Term
Inflammation of the meninges
Definition
Infection spreads thru subarachnoid space w/ CSF increased WBC, proteins, decreased blood glucose. Causes:Viral,fungal parasitic.
Bacterial(fatal) (Streptococcus), pneumoniae or Neisseria meningitis
Term
Subdural Hematoma
Definition
Caused by head trauma. superficial cerebral blood vessels collects in the subarachnoid space. head trauma ranges from acute to chronic
Term
Intracranial Pressure
Definition
Subarachnoid space is filled w/ blood from aneurysms, hemmorrhage, seizures
Term
Papilledema
Definition
Swelling of the optic disc caused by ICP slow venous return
Term
Syncope
Definition
related to baroreceptors in the peripheral blood vessels inadequate blood flow to the brain. fainting weakness of muscles.
Term
Parkinson's Disease
Definition
Midbrain leison
Term
Upper Motor Lesions
Definition
describe all motor system lesions that involve neurons or tracts that are not directly connected to muscles.
Term
Lower Motor Neuron Lesions
Definition
involve neurons or their axons that directly contact muscle (e.g. alpha and gamma motor neurons).
Term
Posterior Cord syndrome
Definition
damaged dorsal column tract. no vibration discriminate touch sensory. Ipsilateral in derms at & below leison
Term
Alpha Sensory IA & Ib
Definition
Primary muscle spindles, golgi tendon organ
Term
Alpha Sensory(II)
Definition
2ndary muscle spindles, skin mechanoreptors
Term
Alpha sensory III
Definition
Skin mechanoreceptors, thermal receptors & nociceptors
Term
Alpha sensory IV
Definition
Skin mechanoreceptors, theraml receptors & nociceptors
Term
Alpha Motor
Definition
Extrafusal skeletal muscle fibers
Term
Gamma Motor
Definition
Intrafusal muscle fibers
Term
Motor B
Definition
Preganglionic autonomic fibers
Term
Motor C
Definition
Postganglionic autonomic fibers
Term
Sympathetic Ganglion
Definition
Preganglionic-Short
Postganglionic-Long
Term
Parasympathetic
Definition
Preganglionic-Long
Postganglionic-Short
Term
Sympathetic segments
Definition
T1-L2
Term
Parasympathetic segments
Definition
CN III,VII,IX,X,S2-S4
Term
Brown Sequard Syndrome
Definition
damage to Anterior Lateral System lose crude touch presents on opposite side.
Term
Hemiballismus
Definition
Violent flinging movements caused from a disturbance in Basal Ganglia
Term
Paroxysmal disorders
Definition
Loss of consciousness. Epilepsy, narcolepsy, migraines
Term
Neoplasia
Definition
uncontrolled tissures, benign or malignant tumor
Term
ataxia
Definition
leison of cerebellar pathways (no sensation) incoordination of movements-Head, neck, limbs.
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