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Neuroanatomy final
Hippocampus, Auditory and Visual systems
95
Science
Undergraduate 3
12/09/2010

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Term
what do the supraoptic nucleus and paraventricular (magnocellular portion) control?
Definition
the posterior pituitary gland
Term
what hypothalamic nuclei are involved in the processes of eating and drinking?
Definition
the ventromedial and dorsomedial nuclei
Term
the ____________ nucleus has descending connections to S2-S4 and activates the sympathetic nervous system
Definition
posterior (hypothalamic nucleus)
Term
the _____________ nucleus receives retinal input and plays a role in the control of circadian rhythms
Definition
suprachiasmatic
Term
what system do the preoptic area and anterior nucleus activate?
Definition
the parasympathetic nervous system
Term
what structures make up the papez circuit?
Definition
posterior nucleus -> anterior nuc of the thalamus -> cingulate cortex -> hippocampal formation -> fornix -> mammilary body
Term
where are the interstitial hypothalamic nuclei located?
Definition
embedded in fibers...which fibers?
Term
which interstitial nucleus is sexually dimorphic (smaller in women and gay men)?
Definition
the 3rd
Term
the ____________ pituitary is derived from the diencephalon whereas the ___________ pituitary is derived from a neural placode
Definition
posterior, anterior
Term
the (anterior/posterior) pituitary contains glial cells, capillaries and neurosecretory granules
Definition
posterior
Term
what hypothalmic nuclei have influences on the anterior pituitary?
Definition
the paraventricular nucleus (parvocellular portion) and the tuberal nuclei (the dorsomedial nucleus, the ventromedial nucleus and the arcuate nucleus)
Term
what nuclei make up the tuberal region of the hypothalamus?
Definition
the dorsomedial nucleus, the ventromedial nucleus and the arcuate nucleus
Term
what hormones are released by the magnocellular portion of the paraventricular nucleus into the bloodstream?
Definition
oxytocin and vasopressin
Term
what are the three subdivisions of the amygdala?
Definition
1. olfactory amygdala-olfactory input
2. basolateral subdivision- cortical like
3. BNST/M/C - subcortical portion (striatum like)
Term
what is urbach-wiethe disease? who was used as a clinical study for this disease?
Definition
a very rare genetic disease in which there is bilateral replacement of the amygdala by calcified tissue early on in life. SM was the patient used as a clinical study
Term
what were some of SM's unusual characteristics due to the loss of his amygdala?
Definition
inability to detect fear, overly friendly demeanor upon first meeting
Term
what three parts make up the hippocampal formation?
Definition
1. the hippocampus proper-divided into CA fields (CAI, CAII and CAIII)
2. dentate gyrus
3. subiculum
Term
what deficits did HM develop after having his temporal lobes removed to alleviate chronic seizures?
Definition
was unable to form new declarative memories due to loss of hippocampal formations. still had intact long-term and procedural memory. tells us that declarative memories are formed in the HF and then stored elsewhere (likely assoc cortices) after a certain period of time in which they are sorted and consolidated.
Term
RB experience loss of declarative memory similar to that of HM after loss of her _____
Definition
CA I? CA III?
Term
what structures are involved in the high road of amygdalar input? the low road?
Definition
high road: thalamic nuclei -> assoc cortices -> amygdala

low road: associated thalamic nuclei -> amygdala
Term
the low road is the (direct/indirect) pathways to the amygdala
Definition
direct
Term
The BL potion of the amygdala has afferents going to the ____________ which in turn passes on information to the _____________. It also has afferents going to the _____ and ______ portions of the amygdala
Definition
Striatum, Prefrontal cortex, Central nucleus, Medial nucleus
Term
where does the BL nucleus of the amygdala get inputs from?
Definition
nucleus basalis, thalamic sensory nuclei and the association cortices
Term
the hypothalamus gets input from which portions of the amygdala?
Definition
the central and medial nuclei, the olfactory amygdala
Term
the __________ is where the stapes attaches to the inner ear
Definition
oval window
Term
true or false: you need equal pressure on both sides for your ears to work maximally
Definition
true
Term
true or false: the shape of the middle ear ossicles are necessary for their function
Definition
false. artificial ossicles of slightly different shapes work just fine. probably shape they are due to evolution from bony fish jaw bones
Term
the basilar membrane is (flexible/stiff) near the helicotrema (apex) and (flexible/stiff) near the oval window (base)
Definition
flexible, stiff
Term
(high/low) frequency sounds are localized to the base of the basilar membrane and (high/low) frequency sounds are localized to the apex of the basilar membrane
Definition
high, low
Term
what type of nt is released by cochlear hair cells?
Definition
glutamate
Term
the spiral ganglion gets input from __________ and gives output to __________, via the _____________
Definition
cochlear hair cells, cochlear muscles, auditory portion of CN VIII
Term
the afferents of outer hair cells join the _____________________
Definition
olivo-cochlear tract
Term
steriocilia bend as a result of the relative bending of the ___________ and ______________ membranes
Definition
tectorial, basilar
Term
true or false: hearing loss can result from taking extremely high doses of antibiotics because of damage to the tectorial membrane
Definition
false. high doses of antibiotics cause loss of outer hair cells resulting in hearing loss
Term
in inner hair cells Ca++ channels open in response to the opening of _____ channels
Definition
K+
Term
mechanically gated potassium channels are located on the ____________ of an inner hair cell and are connected by ___________
Definition
steriocilia, linking filaments
Term
what happens when the steriocilia of inner hair cells are bent?
Definition
if they are bent in the direction of increasing cilia length the K+ channels open causing an excitatory response, if they are bent in the other direction the channels close causing an inhibitory response
Term
what does the stria vascularis do?
Definition
it lets in K+ along it electrochemical gradient
Term
how is sound localized in humans and animals with large heads?
Definition
based on the difference in time of arrival of the sound to the right and left ear
Term
how is sound localized in aquatic animals and animals with small heads?
Definition
based on the differences in intensity of different frequencies perceived by the right and left ear
Term
true of false: the tonotopic organization originating from the basilar membrane is preserved in the cochlear nuclei and primary auditory cortex
Definition
true
Term
the nucleus of the lateral lemniscus has (ipsilateral/contralateral/both) axons that end on the ___________________
Definition
both, inferior colliculus
Term
explain the auditory ascending pathway
Definition
cochlear muscles -> spiral ganglion -> (cochlear nerve) -> cochlear nuclei (dorsal and ventral) -> (trapezoid body) -> superior olivary nucleus -> nucleus of the lateral lemniscus -> (lateral lemniscus) -> inferior colliculus -> Pallidum + GP (or through commisure of inf collic to to contralateral IF) -> superior temporal gyrus
Term
true or false: any lesion beyond the cochlear nuclei would cause affects only on the ipsilateral side
Definition
false. would cause bilateral affects because axons in the cochlear nerve ascend bilaterally after leaving th cochlear nuclei
Term
how does hair cell organization allow you to respond to a wide range of head movements?
Definition
because they are all oriented in differnt directions and thus when head moves some will be activated and others inhibited allowing brain to make spacial adjustments
Term
what are the four structures are innervated by nerves leaving the vestibular nucleus?
Definition
1. the occulomotor nucleus (via CN III, IV, VI and teh ascending MLF)
2. the cerebellum
3. the thalamus (VPI)
4. the spinal cord (via the descending MLF)
Term
what stimuli do the ampulla and utricle preferentially respond to?
Definition
lateral movement
Term
what structure is particularly sensitive to angular head tilt?
Definition
the semicircular ducts
Term
the __________ membrane is embedded with otoconia (small stones) that allows it to move in response to tilt
Definition
otolithic
Term
what structure is the otolithic membrane a part of?
Definition
the macula
Term
when ________ muscles contract the pupil enlarges and when _________ muscles contract the pupil shrinks
Definition
radial, circular
Term
(radial/circular) muscles are controlled by the parasympathetic nervous system
Definition
circular
Term
what is a tapeturn lucidum?
Definition
the irridescent patch in the uvea (?) of nocturnal animals that reflects light
Term
________ fibers control the flattening of the lens (parasympathetic reaction)
Definition
zonula
Term
true or false: all of the photoreceptors at the fovea are rods
Definition
false. all are cones.
Term
what does the suprachiasmatic nucleus control? from where does it receive input?
Definition
circadian clock, retina
Term
the _______________ nuclei sends information involving eye tracking to the visual cortex
Definition
accessory optic
Term
what is the pretectum?
Definition
a group of nuclei that get input from the retina and control pupil constriction ...
Term
what is the consensually constricting pupil reflex?
Definition
both pupils constrict even if only one is exposed to light
Term
the ___________ part of the retina sees the nasal field which the _________ part of the retinal sees the temporal field
Definition
temporal, nasal
Term
true or false: information from the temporal field does not decussate but information for the nasal field does decussate
Definition
Term
what is the result of a lesion at the optic chiasm?
Definition
the right eye can only talk to the right hemisphere and the left eye can only talk to the left hemisphere
Term
describe the pathway of the "what stream"
Definition
retinal ganglion parvocells -> parvocellular layers of LGN -> parvocellular part of V1 -> V2 (illulsory contours), V4 (blob and interblob areas)
Term
what areas of the fusiform gyrus does the "how/where stream" activate?
Definition
V2, V3 (dynamic form), V5 (motion)
Term
the "what stream" is considered the ___________ or small stream pathway and the "how/where stream" is considered the ___________ or large cell pathway
Definition
parvocellular, magnocellular
Term
the ____________ pathway prcoesses visual resolution and the ___________ pathway processes movement
Definition
parvocellular, magnocellular
Term
true or false: the blob area is necessary for seeing but not imagining color
Definition
false. necessary for both
Term
the amplitude (loudness) of a sound is measured in __________
Definition
decibles
Term
what are hertz?
Definition
the measure of sound in cycles/second
Term
___________ is a measure of the frequency of the auditory pathway
Definition
pitch
Term
what are hertz?
Definition
the measure of sound in cycles/second
Term
__________ is a measure of the frequency of sound waves
Definition
pitch
Term
the tensor tympani muscle is innervated by ______________
Definition
cranial nerve V
Term
the stampedius muscle is innervated by __________________
Definition
cranial nerve VII
Term
the stapedius muscle is innervated by _____________
Definition
cranial nerve VII
Term
what is the attenuation reflex?
Definition
when there is a loud noise the tensor tympani and stapedius muscles contract to dampen down the effect of this sound. makes it so we dont hear own own voice as loud as we otherwise would.
Term
what is expressive aphasia? lesions in what brain areas lead to this disordeR?
Definition
inability to produce fluid language. result of lesion in broca's area (left brodmanns area 44 and 45)
Term
a lesion in what area results in receptive aphasia? what are the symptoms?
Definition
receptive aphasia is teh result of lesions in wernikes area (left brodmans area 23) and is characterized by a loss of the ability to comprehend and produce sensical speech
Term
alexia with agraphia is the result of a lesion in the __________________
Definition
left angular gyrus
Term
pure alexia is the result of a lesion in the ______________ and ______________
Definition
left primary visual cortex and splendium of the cc
Term
when the two hemispheres act independently as a result of a severed corpus collosum it is called ___________
Definition
split brain
Term
__________________ is the inability to produce differences in tone and gestures when speaking and is the result of a lesion in ____________________
Definition
expressive aprosodia, right brodman's areas 44 and 45
Term
_____________ is the inability to discriminate between tones and is the result of _____________________. this can also be accompanied by _______________,the inability to recognize tones is music
Definition
receptive aprosodia, right brodman's area 23, amuria
Term
the inability to recognize faces or objects for which one has an expertise is called _____________ and is the result of a lesion in the _____________
Definition
right or bilateral fusiform gyrus
Term
what is capras delusion?
Definition
the idea that familiar people and places are imposters due to a lack of emotional response to them. loss of connections from the fusiform gyrus to the amygdala?
Term
a lesion in the right parietal lobe leads to _____________________
Definition
representational neglect
Term
what area of the brain did phineas gage have damage to following his accident? what were the results of this damage?
Definition
damage primarily to left (and some right) dorsal and ventral medial prefrontal cortex. resulted in complete change in personality, became obstinate and inconsiderate, could no longer follow through with plans
Term
what difficulties did zasetsky face as a result of right occipital lobe damage?
Definition
had a fragmented view of the world, was able to plan and begin things but had trouble following through
Term
which part of your prefrontal cortex is involved in judgement, planning and decision making?
Definition
the ventral medial portion
Term
motivation is influenced by the __________________
Definition
dorsal medial prefrontal cortex
Term
what is the main role of the dorsolateral prefrontal cortex?
Definition
working memory: allows one to select task relevant information and and be able to manipulate it to solve a problem while inhibiting other parts of the brain to stop them from processing distracting information
Term
true or false: an intact DM prefrontal cortex is necessary to learn social cues in childhood
Definition
false. need intact VM prefrontal cortex
Term
what is the somatic marker hypothesis?
Definition
the idea that when making a decision if you have a negative emotional response to one option, will choose the other. lesion in VM prefrontal cortex leads to loss of this phenomenon
Term
what is the stroop effect? a lesion in what cortical area leads to this?
Definition
inability to say color of words on paper if printed in a different color. lesion in DM prefrontal cortex leads to this
Term
what is blind sight?
Definition
the inability to perceive visual information but still be able to do better than chance on visual tasks. due to damage of the primary visual cortex
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