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Neuro
Dru
346
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Professional
01/22/2009

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Term
Fissure
Definition
deep furrow or cleft
Term
Sulcus
Definition
groove on the surface of the brain
Term
Gyrus
Definition
prominent, rounded elevation on the surface of the cerebrum
Term
Brodmann's areas
Definition
map of the cerebral cortex based on cellular architecture w/ 52 areas
Term
Sagittal/Longitudinal fissure
Definition
fissure travels medially front to back and divides brain into two halves
Term
Lateral/Sylvian fissure
Definition
separates temporal from frontal and parietal
Term
Central sulcus
Definition
sulcus running in a coronal plane, in midsagittal cut of the brain follow cingulate sulcus to where it forms marginal ramus and jump ahead one sulcus to find it
Term
Cingulate sulcus
Definition
groove above cingulate gyrus
Term
Parietooccipital sulcus
Definition
separates parietal and occipital lobes
Term
Calcarine fissure
Definition
separates cuneus and lingual regions of occipital lobe and primary visual cortex surrounds this sulcus
Term
Lateral ventricle features
Definition
C/ram shaped w/ ant, inf, and occipital horns
Term
Lateral ventricles are lateral to
Definition
septum pellucidum
Term
Lateral ventricle drains into...through..
Definition
3rd ventricle through IVF of Monro
Term
# of Interventricular foramens of monro
Definition
2
Term
Third ventrical flows into...through...
Definition
fourth ventricle through the Cerebral aqueduct of Sylvius
Term
Superior medullary velum
Definition
tissue posterior to pons and brain stem that projects toward cerebrum that forms the roof of the fourth ventricle
Term
Inferior medullary velum
Definition
tissue posterior to pons and brain stem that projects toward cerebrum that forms the floor of the fourth ventricle
Term
Lateral apertures
Definition
ie the foramina of luschka, 2 lateral openings that drain the 4th ventricle into the subarachnoid space
Term
Medial aperture
Definition
ie foramen of magendie-medial aperture that drains the 4th ventricle into the subarachnoid space
Term
Foramina of luschka is .... to the foramen of magendie
Definition
superior
Term
Central canal of the spinal cord
Definition
enters this after ventricular system if not reabsorb
Term
Choroid plexus
Definition
regenerates csf
Term
Corpus callosum
Definition
interconnecting the cerebral hemisphers except for temporal lobes
Term
temporal lobes are connected by
Definition
anterior commisure
Term
Corpus callosum connects every sense except
Definition
smell
Term
Septum pellucidum
Definition
hangs down from corpus callossum
Term
Septum pellucidum separates
Definition
lateral ventricles
Term
How many lobes does the cerebral cortex have?
Definition
5
Term
What are the lobes of the cerebral cortex?
Definition
Frontal,parietal,temporal,occipital,limbic
Term
4 function of the frontal lobe
Definition
1.higher cognitive control
2.control stereotyped movements
3.control of voluntary movements
4.motor area for speech
Term
Location of frontal lobe
Definition
anterior to the central sulcus and superior to the lateral fissure
Term
Precentral cortex
Definition
primary motor cortex
Term
Precentral gyrus is btwn the
Definition
central sulcus and precentral sulcus
Term
Frontal gyri has three parts
Definition
Superior, middle and inferior
Term
Superior frontal gyrus
Definition
premotor/supplementary motor cortex
Term
Middle frontal gyrus
Definition
premotor/supplementary motor cortex
Term
Parts of the inferior frontal gyrus
Definition
Opercular, triangular, and orbital
Term
Opercular function
Definition
left hemisphere-broca's area-speech and writing
Term
Broca's area function
Definition
speech and writing
Term
Broca's area location
Definition
left hemisphere-opercular and triangular portions of inferior frontal gyrus
Term
Opercular location
Definition
anterior to precentral gyrus
Term
Triangular function
Definition
Left hemisphere-broca's area speech and writing
Term
Triangular location
Definition
anterior and inferior to opercular region with apex pointing toward lateral fissure
Term
Orbital part location
Definition
anterior and inferior to triangular part
Term
Orbital gyri
Definition
Inferior portion of frontal lobe
Term
Olfactory sulcus
Definition
lateral to rectus gyrus and medial to orbital gyri
Term
What lies in the olfactory sulcus?
Definition
Olfactory bulb and tract
Term
What is in between the orbital gyrus and straight (rectus) gyrus
Definition
Olfactory sulcus
Term
Parietal lobe location
Definition
behind central sulcus and above temporal lobe
Term
Functions of parietal lobe
Definition
1. conscious sensation
2. somatic association-body sensation and propioreception
Term
Location of parietal lobe
Definition
Posterior to central sulcus, superior to lateral fissure, and anterior to parietocciptal sulcus
Term
Postcentral sulcus location
Definition
posterior to central sulcus
Term
Intraparietal sulcus
Definition
separates sup and inf parietal lobule
Term
Postcentral gyrus location
Definition
btwn central and post central sulci
Term
Postcentral gyrus broadmann's areas
Definition
1-3
Term
postcentral gyrus function
Definition
primary sensory cortex
Term
Superior parietal lobule location
Definition
superior to supramarginal and angular gyri
Term
Inferor parietal lobule function
Definition
function-left hemisphere-language comprehension
Term
Inferior parietal lobule
Definition
made up of supramarginal and angular gyri
Term
Supramarginal gyri
Definition
upside down u at the apex/termination of lateral sulcus
Term
Angular gyri
Definition
upside down u at the apex of termination of the superior temporal sulcus
Term
Precuneus
Definition
anterior to parietoooccipital sulcus
Term
Paracentral lobule
Definition
Surrounds central sulcus and made up of both the parietal and frontal lobes
Term
Temporal lobe function
Definition
hearing and interpretation of sounds
Term
location of temporal lobe
Definition
inferior to lateral fissure and anterior to the preoccipital notch
Term
Parietal lobe big picture
Definition
motor-ant, sensory-post
Term
3 temporal gyri
Definition
Superior, middle and inferior
Term
Superior gyrus of temporal lobe function
Definition
primary auditory cortex ie Wernicke's area
Term
Occipitotemporal/Fusiform gyrus
Definition
inferior portion of the temporal lobe lateral to the lingual gyrus
Term
Sulcus btwn the lingual and fusiform gyri
Definition
collateral sulcus
Term
Sulcus btwn fusiform and inferior temporal gyri
Definition
Occipitotemporal sulcus
Term
Occipital lobe function
Definition
vision and interpretation of visual images
Term
Occipital lobe location
Definition
posterior to parieotooccipital sulcus and posterior to the pre-occiptal notch
Term
Cuneus gyri
Definition
Wedge shaped region seen in the sagittal section superior to the lingual gyri and posterior to the parietoocciptal sulcus
Term
Lingual gyrus
Definition
Seen in the sagittal view inferior to the cuneus and medial to the occipitotemporal gyri
Term
Calcarine fissure
Definition
Separates the cuneus and lingual gyri
Term
Calcarine cortex location
Definition
cortex surrounding the calcarine fissure
Term
calcarine cortex function
Definition
primary visual cortex
Term
Brodmann's area of calcarine cortex
Definition
17
Term
Pre-occiptal notch
Definition
at the posterior end of the inferior temporal gyrus
Term
Limbic lobe function
Definition
5 f's-feeding, feeling, flight, fighting, and fornication
Term
location of limbic lobe
Definition
medial aspect of cerebral hemisphere
Term
Cingulate Gyrus
Definition
superior to corpus callossum
Term
Cingulate sulcus
Definition
superior to cingulate gyrus
Term
Marginal ramus of cingulate sulcus
Definition
posterior portion of the cingulate sulcus that curves superiorly jump one ahead to find central sulcus
Term
Parahippocampal gyrus location
Definition
located medially to the fusiform gyrus and anterior to the lingual gyrus
Term
Uncus
Definition
medial projection of the parahippocampal gyrus that is inf to the hypothalamus
Term
Hippocampus location
Definition
inside the parahippocampal gyrus and is a striated form of cortex alternating gray and white matter
Term
hippocampus function
Definition
new memory generation
Term
What makes the inferior wall of the inferior horn of the lateral ventricle
Definition
hippocampus
Term
Amygdala location
Definition
on tip of lateral horn of ventricle
Term
Amygdala function
Definition
fear sensor makes heart pound and resp rate increase when afraid
Term
Insula
Definition
island buried in the lateral fissure deep to the temporal lobe
Term
Insula function
Definition
may play a role in olfaction and discriminative touch
Term
Surface of the brain cortex-gray or white matter
Definition
gray matter
Term
interior of brain cortex-gray or white matter
Definition
white
Term
Gray matter is made up of
Definition
cell bodies
Term
white matter is made up of
Definition
axons
Term
Basal ganglia location
Definition
cell bodies buried within the hemispheres
Term
Basal Ganglia function
Definition
precise control of voluntary movement
Term
Basal Ganglia components
Definition
Caudate nucleus and lenticular nuclei
Term
Caudate nucleus forms the
Definition
forms lateral wall of lateral ventricle
Term
Lenticular nucei parts
Definition
Putamen and globus pallidus
Term
Lenticular nuclei is superior to
Definition
caudate nucleus
Term
Putamen is .... to the globus pallidus
Definition
lateral
Term
Putamen is .... to the insula
Definition
medial
Term
Diencephalon components
Definition
Thalamus, hypothalamus, epithalamus, subthalamus, and mamillary bodies
Term
Thalamus function
Definition
all sensory information except olfaction is transmitted to the cerebral cortex via the thalamus
Term
Thalamus forms the...
Definition
lateral wall of the 3rd ventricle
Term
Hypothalamus function
Definition
endocrine and autonomic nervous system function
Term
Hypothalamus forms
Definition
lateral wall of 3rd ventricle
Term
hypothalamus location
Definition
inferior to the thalamus
Term
Other name for the epithalamus
Definition
pineal gland
Term
Pineal gland location
Definition
posterior to thalamus
Term
Pineal gland function
Definition
regulates sleep/wake cycles
Term
imaging use of pineal gland
Definition
calcifies overtime so can be used to identify the midline of the brain
Term
Subthalamus
Definition
posterior to hypothalamus
Term
Mamillary bodies function
Definition
olfactory reflexes
Term
mamillary body location
Definition
projections off the base of the diencephalon inferior to the hypothalamus
Term
Cerebellum components
Definition
hemispheres,vermis, and tonsil
Term
cerebellum function
Definition
processes sensory info to regulate movement
Term
vermis
Definition
midline portion of the cerebellum
Term
tonsil location
Definition
ventral side medial to hemisphere
Term
Brainstem functions
Definition
1. homeostasis
2. sensory, motor and autonomic innervation of the head and neck
3. special senses: taste, hearing, balance, and vision
Term
Components of the brain stem
Definition
Midbrain, pons, medulla, cranial nerves
Term
components of the midbrain
Definition
Tectum and tegmentum
Term
Midbrain location
Definition
region of cerebral aqueduct
Term
Tectum
Definition
made up of superior and inferior colliculi (2 on each side) and forms the roof over the cerebral aqueduct
Term
Tegmentum
Definition
inferior to cerebral aqueduct and tectum
Term
Pons location
Definition
ant to 4th ventricle cerebellum and tegmentum
Term
Spinal cord white and gray matter
Definition
gray-interior, white on periphery
Term
Dura mater layers
Definition
Periosteal/endosteal, meningeal
Term
Periosteal/endosteal
Definition
lines interior of the cranial cavity
Term
meningeal layer of dura mater
Definition
dives down in an area like a falx
Term
Potential spaces of the dura
Definition
epi and subdural
Term
epidural
Definition
above dura
Term
subdura
Definition
below dura
Term
Reflections
Definition
folds
Term
Reflection of the dura mater
Definition
falx cerebri, tentorium cerebelli, falx cerebelli, and diaphragma sellae
Term
Falx cerebri
Definition
attaches to cristi galli of frontal bone and splits cerebral hemispheres
Term
Tentorium cerebelli anchors and position
Definition
anchored to ant/post clinoid processes of sphenoid bone and is the horizontal separator of the cerebrum and cerebellum
Term
Tentorial incisure/notch
Definition
u shaped opening ant to tentorium cerebelli where brainstem passes through
Term
supratentorial space
Definition
space above the tentorium cerebelli
Term
infratentorial space
Definition
space below tentorium cerebelli
Term
falx cerebelli
Definition
vertical dura mater btwn cerebellar hemispheres
Term
Diagphragma sellae
Definition
horizonal membrane that covers the sella turcica region where the pituitary is housed
Term
Dural venous sinuses
Definition
blood filled spaces formed by separation of the dura that drain the veins of the brain
Term
Superior sagittal sinus
Definition
superior midsaggital sinus that is triangular in shape and enlarges as it travels posteriorly that drains into the confluence of sinuses
Term
confluence of sinuses
Definition
posterior confluence that drains the straight, superior sagittal and occipital sinuses and flows into the transverse sinus
Term
Inferior sagittal sinus
Definition
inferior midsagittal sinus that together w/ the great vein of galen forms the straight sinus
Term
Location of the inferior sagittal sinus
Definition
located btwn falx cerebri and the tentorium cerebelli
Term
Straight sinus
Definition
drains great vein of galen and inferior sagittal sinus and is drained by the confluence of sinuses
Term
Transverse sinus location
Definition
runs attachment of tentorium cerebelli to the skull
Term
transverse sinus
Definition
runs into the sigmoid sinus
Term
sigmoid sinus location
Definition
runs along petrous portion of the temporal bone
Term
sigmoid sinus
Definition
drains the transverse sinus and the superior petrosal sinus and flows into the internal jugular vein
Term
cavernous sinus
Definition
drains into the superior and inferior petrosal sinuses
Term
Cavernous sinus location
Definition
on either side of the sella turcica
Term
Clinical implication of the cavernous sinus
Definition
in communication w/ vessels from the face so it has the potential for infection
Term
Occipital sinus
Definition
small posterior sinus that drains into the confluence of sinuses
Term
Superior petrosal sinus
Definition
drains into the sigmoid sinus and receives flow from the cavernous sinus
Term
Inferior petrosal sinus
Definition
receives flow from the cavernous sinus and drains into the internal jugular vein
Term
Internal jugular vein drainage
Definition
drains the inferior petrosal and sigmoid sinuses
Term
Middle meningeal artery
Definition
supplies the bones of the skull
Term
What kind of hemorrhage is one of the middle meningeal artery?
Definition
an epidural hemorrhage
Term
Anterior cranial fossa blood supply
Definition
middle meningeal artery and others
Term
Middle cranial fossa blood supply
Definition
middle meningeal artery and others
Term
Posterior cranial fossa blood supply
Definition
meningeal branches of the occipital artery
Term
Blood supply to the arachnoid mater
Definition
avascular
Term
Arachnoid mater consists of
Definition
cells and bundles of collagen which form arachnoid trabeculae that project inferiorly giving weblike appearance
Term
Subarachnoid space
Definition
where cerebrospinal fluid drains into from ventricles and contains the vessels (vessels are not in the mater)
Term
Subarachnoid cisterns
Definition
enlargements of the subarachnoid space
Term
Cerebromedullary/Cisterna magna
Definition
just below the cerebellum
Term
Pontine cistern
Definition
anterior to the pons
Term
Interpeduncular cistern
Definition
btwn the cerbral peduncles which are the stalks that hold up the hemispheres
Term
Quadrigeminal cistern
Definition
near corpora quadrigemina
Term
Ambient cistern
Definition
around the periphery of brain on sides
Term
Lumbar cistern
Definition
near cauda equina
Term
Arachnoid villi
Definition
projection of arachnoid mater into the dural venous sinuses
Term
Arachnoid villi have
Definition
arachnoid granulations that increase w/ age
Term
Arachnoid villi structure
Definition
core of collagen fibers covered by arachnoid cells and sinus endothelial cells with channels btwn arachnoid cells that allow csf to contact endothelial cells
Term
Arachnoid villi function
Definition
csf is transported from the granulations into the dural venous sinuses through the endothelia cells
Term
Pia mater
Definition
perivascular sheath (which eventually disappears) that follows the contours of the brain that separates the subarachnoid space from the perivascular spaces
Term
Fourth ventricle drains into
Definition
Lateral/medial apertures or the central canal of the spinal cord
Term
CSF function
Definition
mechanical support of the cns
Term
Source of csf
Definition
choroid plexus within the ventricles
Term
Choroid plexus is formed by
Definition
pia mater and cells lining the ventricles which are epithelial cells with microvilli and tight junctions that makeup the blood csf barrier as well as fenestrated capillaries deep to the epithelium
Term
Where in the choroid plexus is csf secreted
Definition
apical surface of the epithelial cells
Term
CSF composition
Definition
clear colorless with little protein and is derived from blood but not ultrafiltrate because it has a different ionic concentration
Term
Circulation of csf
Definition
from the ventricles to the subarachnoid space or central canal of the spinal cord
Term
What helps the circulation of csf?
Definition
cilia on ependymal cells lining the ventricles and arterial pulsations
Term
Blood brain barrier function
Definition
limits the passage of substances from the blood into the CSF to maintain a stable environment for neurons
Term
Make up of blood brain barrier
Definition
endothelial cells that line vessels that have tight juctions and few pinocytic vesicles (endocytotic)
Term
Blood brain barrier is crossed by
Definition
1. diffusion of lipid soluble substances
2. facilitated or energy dependent receptor mediated transport of water soluble substances
3. ions across channels
Term
Circumventricular organs (not a list)
Definition
peripheral organs of the brain that lack a blood brain barrier because they need to monitor what is going on in the body for control purposes
Term
Do tumors have a blood brain barrier
Definition
no
Term
What can disrupt the BBB?
Definition
trauma, TIA, meningitis inflammation, seizures, and hypertension
Term
mass lesion
Definition
anything abnormal that occupies the volume within the cranial cavity ie tumor, hemorrhage, abcess, edema or hydrocephalus
Term
mass effect
Definition
distortion of normal brain geometry due to a mass lesion ie only so much room for stuff in the cavity so creates pressure
Term
herniation
Definition
displacement of intracranial structures from one compartment to another as a result of a mass effect
Term
Types of herniation
Definition
subfalcine, central, transtentorial, tonsillar
Term
Subfalcine herniation
Definition
herniation of central structures such as the cingulate gyrus underneath the falx cerebri that usually has no clinical symptoms ie a shifting across the brain midline
Term
Central herniation
Definition
herniation of the brainstem downward toward the foramen magnum
Term
Effects of a central herniation
Definition
puts traction on CNVI -> lateral rectus palsy
Term
Transtentorial herniation
Definition
herniation of the medial part of the temporal lobe inferiorly through the tentorial notch which has a sharp edge that can cause damage
Term
Effects of a transtentorial herniation
Definition
1.Blown pupil
2.hemiplegia
3.Altered level conciousness/coma due to distortion of the reticular formation within the midbrain
Term
Blown pupil
Definition
a pupil that is dilated and unresponsive to light-can be due to a compression of CNIII and is usually ipsilateral (same side) as the lesion
-observed with a transtentorial hernia
Term
Hemiplegia
Definition
paralysis on half the body due to a compression of motor tracts within the cerebral peduncles-one of the results of a transtentorial hernia
Term
Tonsillar herniation
Definition
herniation of the cerebellar tonsils
Term
Effects of tonsillar herniation
Definition
leads to compression of the brain stem that may cause respiratory arrest
Term
Signs and symptoms of a meningeal irritation
Definition
1.headache
2.lethargy
3.sensitivity to light and noise
4.fever
5.nuchal rigidity (stiff neck) and unable to touch chin to chest-ie demonstrates kernigs and brudzinski's sign
Term
kernig's sign
Definition
pain in the hamstrings when knees are straightened with hips flexed
Term
brudzinski's sign
Definition
flexion at neck causes hips to flex
Term
Normal lumbar puncture in adults (1.WBC#,2.WBC type, 3.protein, 4.glu)
Definition
1.few less than 10
2. lymphocytes
3.minimal 15-45
4.50-100
Term
Bacterial meningitis lumbar puncture
(1.WBC#,2.WBC type, 3.protein, 4.glu)
Definition
1.many 500-1000
2.polymorphonuclear leukocytes
3.high 100-1000
4.reduced less than 40
Term
Viral meningitis lumbar puncture
(1.WBC#,2.WBC type, 3.protein, 4.glu)
Definition
1.some 10-300
2.lymphocytes
3.some 50-100
4.normal
Term
TB meningitis lumbar puncture
(1.WBC#,2.WBC type, 3.protein, 4.glu)
Definition
1.some 10-200
2.lymphocytes
3.elevated 100-200
4.reduced less than 50
Term
Lumbar puncture location
Definition
Btwn L3-4 or 4-5 b/c spinal cord ends at L1
Term
Layers penetrated by a lumbar puncture
Definition
skin, subcutaneous tissues, supraspinous ligament, intraspinous ligament, ligamentum flavum, extra dural space, dura matter, subdural space, arachnoid matter and CSF is in the subarachnoid space
Term
Cerebral Ischemia-Infarction
Definition
also know as stroke which is a blockage of blood flow to a particular area of the brain and is often caused by cerebral vascular disease
Term
Two types of Cerebral ischemia/infarction
Definition
1. Thromobotic occulsion
2. Embolic Occlusion
Term
Intracranial hemorrhage types
Definition
1.intracerebral
2.subarachnoid
3.subdural
4.epidural
Term
Intracerebral hemorrhage
Definition
occurs within the substance of the brain and is a type of hemorrhagic stroke
Term
Subarachnoid hemorrhage
Definition
type of hemorrhagic stroke
Term
Subdural hemorrhage
Definition
venous origin and is a bleed not a stroke
Term
Epidural stroke
Definition
arterial and is a bleed not a stroke
Term
ischemia
Definition
reduction in blood flow
Term
infarction
Definition
death of tissue as a result of reduced blood flow for more than a few minutes
Term
syncope
Definition
a generalized reduction in blood flow to the brain due to systemic hypotension ie fainting due to low blood pressure
Term
Transient Ischemic Attacks (TIAs)
Definition
a neurological deficit lasting <24 hrs (usually 5-20 min) and complete strokes are often preceded by TIAs days, weeks, or months prior
Term
TIA causes
Definition
often due to low blood flow as a result of arterial stenosis or embolism
Term
Thrombotic strokes cause
Definition
something from the brain causes a more and more blocked blood flow
Term
Thrombotic stroke description
Definition
often present with fluctuating symptoms that worsen with time and are often preceded by TIAs about 10 to 20% of the time
Term
Embolic strokes cause
Definition
something from systemic circulation came and completely blocked the blood flow
Term
Embolic stroke desc
Definition
usually present with a neurological deficit that is maximal at onset
Term
Neurons are dependent on ... metabolism
Definition
aerobic
Term
Ischemic core
Definition
center of anaerobic area where neurons die due to lack of oxygen and glucose
Term
Ischemic penumbra
Definition
area around anaerobic area that gets a partial perfusion of oxygen
Term
Result of ischemic penumbra
Definition
neurons switch to anaerobic metabolism-> get lactic acid -> acidosis and excessive release of glutamate -> activates NMDA receptors -> increase intracellular calcium -> activation of proteases, lipases, membrane depol, free radical damage to DNA, proteins and FA
Term
Risk factors for stroke
Definition
1. Hypertension-treatable-damage vessels leading to block
2.Diabetes-treatable-damage vessels leading to block
3. Hypercholesterolemia-lead to block
4. Smoking-damage vessels
5. family history
6. cardiac disease
7. prior history
Term
Treatment of stroke
Definition
1. Brain CT to rule out hemorrhage
1a. MRI to confirm site of clot
1b. heart ultrasound to find source of block
2. tissue plasminogen activator (t-PA)-antithrombolytic agent
3. Heparin-don't give to hemorrhagic stroke
4. Preventative meds like aspirin
5. Current research-meds that interfere with stroke mechs
Term
These provide arterial supply to the brain
Definition
Internal carotid (ant) and the vertebral arteries (post)
Term
This connects the internal carotid system with the vertebral system
Definition
cerebral circle of willis
Term
Internal carotid supplies most of
Definition
the cerebrum and diencephalon
Term
The vertebral artery supplies
Definition
posterior cerebrum, diencephalon, brainstem, cerebellum, and cervical spinal cord
Term
vertebral artery enters the cranial cavity
Definition
through the foramen magnum
Term
vertebral artery fuses
Definition
to form the basilar artery
Term
Internal carotid parts
Definition
1.Cervical
2.Petrous
3.Cavernous
4.Supraclinoid/intracranial/cerebral part
Term
Cervical part of ICA
Definition
from bifurcation to the carotid canal (ie base of skull)
Term
Petrous part of ICA
Definition
(carotid siphon) -within the carotid canal in the petrous portion of the temporal bone
Term
Cavernous part of ICA
Definition
(carotid siphon)
1.within the cavernous sinus
2.sends branches to the trigeminal ganglion and the pituitary gland
Term
Supraclinoid/intracranial/cerebral part of ICA
Definition
1. once it pierces the dura mater ie leaves the cavernous sinus
Term
5 branches of the ICA
Definition
1.Ophthalmic
2.Posterior communicating aa
3.Anterior choroidal artery
4. Anterior cerebral arteries
5. Middle cerebral arteries
Term
Ophthalmic artery
Definition
supplies the orbit and optic nerve
(branch of ICA)
Term
PComm artery
Definition
anastomose w/ posterior cerebral artery
Term
Anterior choroidal artery
Definition
supplies the crus cerebri of the midbrain, lateral geniculate body of the thalamus, globus pallidus, caudate nucleus, amygdala, hypothalamus, posterior limb of internal capsule, optic radiations, optic tract, and hippocampus
Term
Two terminal branches of the ICA
Definition
Ant and middle cerebral arteries
Term
Links the two sides of the anterior cerebral artery
Definition
Anterior communicating artery
Term
Ant CA location
Definition
located in longitudinal fissure
Term
Ant CA general blood supply
Definition
supplies medial aspect of the brain
Term
Specific blood supply of Ant CA
Definition
supplies the cingulate gyrus, optic chiasm and the medial aspect of the frontal and parietal lobes including the motor and somatosensory areas of the cortex that supply the lower limbs
Term
Branches of Ant CA
Definition
1.callosomarginal
2.pericallosal
3.lenticulostriate
Term
Callosomarginal artery
Definition
branch of ant CA that follows the cingulate gyrus (just superior to the gyrus)
Term
pericallosal artery
Definition
branch of ant CA that supplies corpus callosum and runs just above it
Term
Callosomarginal artery relative to pericallosal artery
Definition
CM is the proximal branch of ant CA and runs superior to the distal pericallosal artery
Term
Lenticulostriate arteries
Definition
supply the internal capsule and basal ganglia
Term
Signs and symptoms of an infarct of the ant CA
Definition
1. Behavioral changes (frontal lobe)
2. Contralateral leg weakness (precentral gyrus)
3. contralateral leg sensory loss (post central gyrus)
Term
Why does an occlusion of ant CA cause weakness of the contralateral leg?
Definition
portion of the primary motor cortex in the precentral gyrus for the lower limbs is found on the medial aspect of the brain
Term
Why does an occlusion of ant CA cause sensory loss on the contralateral leg?
Definition
portion of the primary sensory cortex in the post central gyrus for the lower limbs is found on the medial aspect of the brain
Term
Middle Cerebral Arteries desc
Definition
larger of the two terminal branches of the ICA
Term
MCA location
Definition
runs in the lateral sulcus (sylvian fissure)
Term
lenticulostriate arteries of the MCA
Definition
penetrate the anterior perforating substance to supply the basal ganglia and internal capsule
Term
MCA bifurcation
Definition
splits into superior and inferior divisions at the sylvian fissure
Term
Superior division of the MCA supplies
Definition
lateral surface of the cortex superior to the lateral cerebral fissure (frontal and parietal lobes)
Term
Inferior division of the MCA supplies
Definition
The lateral surface of the cortex inferior to the lateral cerebral fissure (upper temporal lobe)
Term
Optic radiation location
Definition
arch from the thalamus (lateral geniculate nucleus) to the occipital cortex
Term
Blood supply to the optic radiations
Definition
MCA
Term
Superior Division of MCA infarct
Definition
contralateral face and arm weakness (precentral gyrus) or contralateral face and arm sensory loss (postcentral gyrus)
Term
Superior division of Left MCA infarct
Definition
Broca's aphasia-impaired speech due to motor deficit
Term
Why does the MCA affect motor and sensory function for the upper body?
Definition
The primary motor (precentral) and sensory (postcentral) areas for the upper body are on the lateral parts of the brain
Term
Inferior division infarct of left MCA
Definition
Wernicke's/auditory aphasia-impaired comprehension of language despite normal hearing
Term
Inferior division of right MCA infarct
Definition
hemineglect-patient is unaware of the existence of the left half of his/her body or environment due to some of parietal lobe being supplied by inf. MCA
Term
MCA stem infarct
Definition
1. contralateral hemiplegia
2.contralateral hemianesthesia
3.visual field defects due to optic radiations
4.global aphasia due to left stem
Term
Optic radiation desc
Definition
collection of relay neurons in the lateral geniculate nucleus (thalamus) that carry visual information to the visual cortex
Term
Lenticulostriate of MCA or Ant CA infarct
Definition
contralateral hemiparesis-paralysis/weakness affecting one side of the body
Term
vertebral artery origin and route
Definition
branch from the subclavian pass through the transverse foramina of the cervical vertebrae and enter the foramen magnum
Term
Branches of vertebral arteries
Definition
1.anterior spinal artery
2.Posterior inferior cerebellar PICA
3.Posterior spinal
Term
anterior spinal artery
Definition
branch of vertebral artery that fuses with its partner to form a single branch that runs with the anterior median fissure
Term
anterior spinal artery supply
Definition
supplies anterior 2/3 of the cervical spinal cord and the anterior and medial medulla including the medullary pyramids
Term
PICA
Definition
branch of the vertebral artery that supplies the inferior surface of the cerebellum, lateral part of the rostral medulla, and choroid plexus of the fourth ventrical
Term
Posterior spinal artery source
Definition
branches from the vertebral artery or from the PICA
Term
Posterior spinal artery supply
Definition
each descends near the dorsal roots and supplies the posterior 1/3 of the cervical spinal cord and the posterior part of the caudal medulla
Term
Basilar artery path
Definition
runs rostrally along the anterior surface of the pons and bifurcates to form two posterior cerebral arteries
Term
Branches of the basilar artery
Definition
1.Anterior inferior cerebellar artery
2.Superior cerebellar artery
3.Pontine artery
4.labyrinthine/internal auditory artery
5.Posterior cerebral arteries
Term
Anterior inferior cerebellar artery AICA
Definition
supplies the cerebellum and lateral part of the caudal pons
Term
Superior cerebellar artery
Definition
supply the cerebellum, lateral part of middle pons and pineal gland
Term
Pontine artery
Definition
supplies the pons
Term
Labyrinthine/Internal auditory artery
Definition
supplies the inner ear
Term
Posterior cerebral arteries location
Definition
curve around the midbrain
Term
PCA supply
Definition
1. midbrain
2.medial and inferior surfaces of the temporal and occipital lobes including the visual areas of the cerebral cortex
thalamus and globus pallidus via central branches
Term
PCA infarct
Definition
1.visual field defects (occipital)
2.contralateral hemiparesis or contralateral hemianesthesia if thalamus and internal capsule are affected
Term
Cerebrum-medial surface blood supply
Definition
ACA
Term
Cerebrum-lateral surface blood supply
Definition
MCA
Term
Cerebrum-superior surface of temporal lobe blood supply
Definition
MCA
Term
Cerebrum-inferior surface of temporal lobe blood supply
Definition
PCA
Term
Cerebellum blood supply
Definition
Superior Cerebellar artery
PICA
AICA
Term
Thalamus blood supply
Definition
Pcomm
PCA
Basilar
Term
Basal Ganglia blood supply
Definition
ACA
MCA
both by their branches the lenticulostriate arteries
Term
Internal capsule blood supply
Definition
ACA
MCA
both by their branches the lenticulostriate arteries
Term
Optic chiasm blood supply
Definition
ACA
Term
Optic tract blood supply
Definition
Anterior choroidal arteries
PCA
Term
Optic radiations blood supply
Definition
MCA
PCA
Term
Midbrain blood supply
Definition
PCA
Superior cerebellar
Basilar
Term
Pons blood supply
Definition
basilar
AICA
Superior cerebellar artery
Term
Medulla blood supply
Definition
Vertebral Artery
Anterior spinal artery
PICA
Posterior spinal artery
Term
What vessels affect CNVI function
Definition
AICA and Labyrinthine b/c VI runs btwn them
Term
What vessels affect CNIII function
Definition
PCA and superior cerebellar because CNIII runs btwn them
Term
The inferior frontal gyrus is divided into 3 subdivisions by
Definition
the anterior and ascending rami of the lateral fissure
Term
Cingulate gyrus function
Definition
1. emotional processing of pain
2. contains supplementary motor area where complex movements are planned and executed
Term
Cingulate sulcus function
Definition
cortical areas are involved in initial stages of movement generation
Term
Cerebral peduncles
Definition
stalks are bundles of nerve fibers that make up the two haves of the midbrain
Term
Cerebral peduncle location
Definition
visible as narrow vertical grooves and elevations just above the pons and extending into the cerebrum
Term
Interpeduncular fossa
Definition
part of subarachnoid space located btwn the cerebral peduncles
Term
Interpeduncular fossa location
Definition
located on the ventral side of the brain stem
Term
Interpeduncular fossa contents
Definition
contains mamillary bodies and oculomotor nerves
Term
Medulla pyramids location
Definition
elongated elevations on the anterior surface of the medulla on either side of the midline
Term
Medulla pyramids function
Definition
ipsilateral fiber tracts carrying motor info from the primary motor cortex to the spinal cord
Term
Pyramidal decussation
Definition
region where the pyramidal fibers cross the midline of the medulla located at the inferior end of the medulla just superior to the spinal cord
Term
Medulla olives
Definition
elevations just lateral to the pyramids
Term
Superior colliculi function
Definition
visual system relay and reflexes
Term
inferior colliculi function
Definition
auditory system relay and reflexes
Term
Anterior commissure location
Definition
bundle of nerve fibers crosses the midline near the anterior end of the 3rd ventricle
Term
Anterior commisure function
Definition
connects temporal lobes as well as the olfactory bulbs
Term
Posterior commissure
Definition
bundle of nerve fibers just inferior ot the pineal body
Term
Posterior commissure marks what
Definition
the junction of the diencephalon anteriorly with the mesencephalon posteriorly
Term
Posterior commissure function
Definition
connects parts of the midbrain
Term
Pineal gland secretes what
Definition
melatonin
Term
Hypothalamus influences the secretion of what
Definition
pituitary gland
Term
Light microscopy microscope appearance of astrocytes vs oligodendrocytes
Definition
astrocytes have larger paler nuclei while oligodendrocytes have smaller darker nuclei
Term
ependymal cell shape for lab
Definition
cuboidal or low columnar in shape and they can be ciliated
Term
endoneurium
Definition
packing of loose vascular supporting tissue that surrounds each individual nerve fiber and its investing schwann cell
Term
fascicles
Definition
bundle of nerve fibers several of which make up a peripheral nerve
Term
perinerium
Definition
layer of flat epithelial cells that invests the condensed layer of collagenous tissue surrounding a fascicles
Term
epinerium
Definition
layer of loose collagenous tissue that binds multiple fascicles together and is condensed peripherally to form a strong cylindrical sheath
Term
can a nerve contain both myelinated and unmyelinated fibers in it
Definition
yes
Term
can a given schwann cell associate with both myelinated and unmyelinated fibers
Definition
no
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